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[Presented at HWO25 "Towards the Habitable Worlds Observatory: Visionary Science and Transformational Technology"] A primary goal of the Habitable Worlds Observatory (HWO) is to detect and measure the abundance of biosignature molecules, such as water (H2O) an…
datacite
Ruffio, Jean-Baptiste
2025
置信度 0.66
HWO25
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[Presented at HWO25 "Towards the Habitable Worlds Observatory: Visionary Science and Transformational Technology"] A primary goal of the Habitable Worlds Observatory (HWO) is to detect and measure the abundance of biosignature molecules, such as water (H2O) an…
datacite
Ruffio, Jean-Baptiste
2025
置信度 0.66
HWO25
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Traditional exoplanet screening frameworks typically rely on scalar habitability metrics or equilibrium-centered criteria. The present work introduces a layered persistence geometry framework designed to evaluate exoplanet systems under bounded adaptive, occup…
datacite
Atalebe, Stephen
2026
置信度 0.66
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Traditional exoplanet screening frameworks typically rely on scalar habitability metrics or equilibrium-centered criteria. The present work introduces a layered persistence geometry framework designed to evaluate exoplanet systems under bounded adaptive, occup…
datacite
Atalebe, Stephen
2026
置信度 0.66
-
The information fields framework proposes a five-stage transduction cascade through which the field's organizational signal propagates from the subatomic level to conscious representation. White Papers I through VIII established the physical formalism of the c…
datacite
de Lima Azevedo, Erico, Korotkov, Konstantin G, Bazzo, Maria Luiza, Schveitzer, Mariana
2026
置信度 0.66
information fieldstransduction cascadeFroehlich condensatesDavydov solitonsbiophotons
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The information fields framework proposes a five-stage transduction cascade through which the field's organizational signal propagates from the subatomic level to conscious representation. White Papers I through VIII established the physical formalism of the c…
datacite
de Lima Azevedo, Erico, Korotkov, Konstantin G, Bazzo, Maria Luiza, Schveitzer, Mariana
2026
置信度 0.66
information fieldstransduction cascadeFroehlich condensatesDavydov solitonsbiophotons
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datacite
Alçiçek, Hülya, Tucker, Maurice E.
2026
置信度 0.66
-
datacite
Alçiçek, Hülya, Tucker, Maurice E.
2026
置信度 0.66
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This dataset supports the manuscript "Crater-scale lipid compositional gradients at Hverfjall, Iceland: Implications for biosignature redistribution and sampling in a Mars analogue crater". It contains data from a transect across the Hverfjall tuff ring, north…
datacite
Nauny, Philippe
2026
置信度 0.66
HverfjallMars analoguebiosignaturesATPlipid biomarkers
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preprints
2023
置信度 0.74
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preprints
2023
置信度 0.74
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preprints
2022
置信度 0.74
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preprints
2023
置信度 0.74
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preprints
2023
置信度 0.74
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preprints
2023
置信度 0.74
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preprints
2023
置信度 0.74
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preprints
2023
置信度 0.74
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preprints
2021
置信度 0.74
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preprints
2021
置信度 0.74
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preprints
2022
置信度 0.74
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preprints
2022
置信度 0.74
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preprints
2021
置信度 0.74
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preprints
2020
置信度 0.74
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preprints
2023
置信度 0.74
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preprints
2019
置信度 0.74
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preprints
2021
置信度 0.74
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preprints
2020
置信度 0.74
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preprints
2020
置信度 0.74
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preprints
2020
置信度 0.74
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preprints
2020
置信度 0.74
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preprints
2021
置信度 0.74
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preprints
2021
置信度 0.74
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preprints
2022
置信度 0.74
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preprints
2021
置信度 0.74
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crossref
James W. Baurley, Christopher S. McMahan, Carolyn M. Ervin, Bens Pardamean 等
2018-02-04T19:48:00Z
置信度 0.70
-
crossref
V Anaparti, I Smolik, X Meng, N Mookherjee 等
2017-09-19T16:40:14Z
置信度 0.70
-
ABSTRACT It is widely anticipated that the James Webb Space Telescope (JWST) will be transformative for exoplanet studies. It has even been suggested that JWST could provide the first opportunity to search for biosignatures in an alien atmosphere using transmi…
crossref
Thomas Mikal-Evans
2021-11-18T20:14:35Z
置信度 0.70
-
crossref
Mark van Zuilen, Dylan Wilmeth, Sami Nabhan, Moritz Liesegang 等
2023-12-11T11:28:26Z
置信度 0.70
-
373 Background: Microvesicles are principally derived either from the endosomal pathway (as exosomes) or shed directly from the plasma membrane. They are between 40-500 nm in diameter and are secreted by most cell types, including tumor cells. In circulation, …
crossref
D. Spetzler, T. Tinder, S. Kankipati, M. Maheshwari 等
2017-02-23T18:48:23Z
置信度 0.70
-
crossref
Xinchuan Huang, David Schwenke
2024-05-07T16:33:58Z
置信度 0.70
-
crossref
L.A. Melim, R. Liescheidt, D.E. Northup, M.N. Spilde 等
2009-12-07T11:47:12Z
置信度 0.70
-
crossref
Md Ehsanur Rahman, Tyseer Ninad, Md Anwarul Islam Aion, Md Rafin Haque 等
2026-02-18T21:13:38Z
置信度 0.70
-
Psychiatry remains in a permanent state of crisis, which fragmented psychiatry from the field of medicine. The crisis in psychiatry is evidenced by the many different competing approaches to psychiatric illness including psychodynamic, biological, molecular, p…
preprints
Drozdstoy Stoyanov, Michael Maes
2020
置信度 0.74
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Endometriosis is a multifactorial disease with poorly understood etiology, and reflecting an evolutionary nature where genetic alterations accumulate throughout pathogenesis. Our objective was to characterize the heterogeneous pathological process using parsim…
crossref
Mones Abu-Asab, Ming Zhang, Dennis Amini, Nihad Abu-Asab 等
2011-12-13T21:01:49Z
置信度 0.70
-
Abstract Biosignature gas research has been growing in recent years thanks to next-generation space- and ground-based telescopes. Methanol (CH 3 OH) has many advantages as a biosignature gas candidate. First, CH 3 OH’s hydroxyl group (OH) has a unique spectral…
crossref
Jingcheng Huang, Sara Seager, Janusz J. Petkowski, Zhuchang Zhan 等
2022-06-28T19:36:12Z
置信度 0.70
-
Abstract Direct-imaging observations of terrestrial exoplanets will enable their atmospheric characterization and habitability assessment. Considering Earth, the key atmospheric signatures for the biosphere are O 2 and the photochemical product O 3 . However, …
crossref
Mario Damiano, Renyu Hu, Bertrand Mennesson
2023-09-15T05:08:42Z
置信度 0.70
-
crossref
J. J. McGough, J. T. McCracken, A. L. Cho, E. Castelo 等
2014-05-06T00:08:06Z
置信度 0.70
-
Abstract With the recent discoveries of terrestrial planets around active M-dwarfs, destruction processes masking the possible presence of life are receiving increased attention in the exoplanet community. We investigate potential biosignatures of planets havi…
crossref
Markus Scheucher, J. L. Grenfell, F. Wunderlich, M. Godolt 等
2018-08-06T13:19:25Z
置信度 0.70
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Abstract Breast cancer (BC) is a leading cause of mortality among women. Comorbidity with mood disorders is a condition either disregarded or underdiagnosed in BC patients, but that might ultimately jeopardize health trajectories. This is supported by evidence…
europepmc
Alessandra Berry, Letizia Giona, Barbara Collacchi, Sara Capoccia 等
2025
置信度 0.80
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Abstract A planet’s atmospheric constituents (e.g., O 2 , O 3 , H 2 O v , CO 2 , CH 4 , and N 2 O) can provide clues to its surface habitability, and may offer biosignature targets for remote life detection efforts. The plethora of rocky exoplanets found by re…
crossref
Howard Chen, Eric T. Wolf, Ravi Kopparapu, Shawn Domagal-Goldman 等
2018-11-15T18:44:17Z
置信度 0.70
-
Metal complexes of porphyrins and porphyrin-type compounds are ubiquitous in all three domains of life, with hemes and chlorophylls being the best-known examples. Their diagenetic transformation products are found as geoporphyrins, in which the characteristic …
pubmed
Hannes Lukas Pleyer, Ralf Moeller, Akira Fujimori, Stefan Fox 等
2022 Jul
置信度 0.82
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crossref
Laura M. Barge, Laura E. Rodriguez, Jessica M. Weber, Bethany P. Theiling
2021-12-13T15:46:48Z
置信度 0.70
-
europepmc
Georgios V. Thomaidis, Konstantinos Papadimitriou, Sotirios Michos, Evangelos Chartampilas 等
2023
置信度 0.80
-
ABSTRACT Being the backbone element of deoxyribonucleic acid, phosphorus is a key component in the search for life in the Universe. To aid in its detection, we present line emissivity ratios for the five lowest-lying forbidden [P ii] transitions, namely those …
crossref
Kevin Hoy, Sultana N Nahar, Anil K Pradhan
2023-02-23T00:35:33Z
置信度 0.70
-
crossref
Leonie Venter, Zander Lindeque, Peet Jansen van Rensburg, Francois van der Westhuizen 等
2014-05-31T07:02:21Z
置信度 0.70
-
crossref
Xinfang Huang, Yanzhi Guo, Chunde Bao, Nan Shen
2011-07-22T14:53:00Z
置信度 0.70
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crossref
Yashu Liu, Lynn Yieh, Tao Yang, Wilhelmus Drinkenburg 等
2016-08-23T02:24:40Z
置信度 0.70
-
Iron-oxidizing bacteria occupy a distinct environmental niche. These chemolithoautotrophic organisms require very little oxygen (when neutrophilic) or outcompete oxygen for access to Fe(II) (when acidophilic). The utilization of Fe(II) as an electron donor mak…
crossref
Melissa A. Merrill Floyd, Amy J. Williams, Andrej Grubisic, David Emerson
2018-07-25T11:28:27Z
置信度 0.70
-
crossref
H. R. Chang
2017-02-24T02:41:10Z
置信度 0.70
-
The inability to unambiguously distinguish the biogenicity of microfossil-like structures in the ancient rock record is a fundamental predicament facing Archean paleobiologists and astrobiologists. Therefore, novel methods for discriminating biological from no…
crossref
Craig P. Marshall, Alison Olcott Marshall, Jade B. Aitken, Barry Lai 等
2017-11-14T14:23:29Z
置信度 0.70
-
Abstract We have developed a novel, versatile, multiplexed exosome-based diagnostic platform that can identify highly specific and sensitive disease biosignatures. This platform has been used to identify a plasma-based exosome biosignature for prostate cancer …
crossref
Christine D. Kuslich, Traci Pawlowski, Jeff Kimbrough, Ta Deng 等
2011-02-25T18:14:05Z
置信度 0.70
-
crossref
Adriano Guido, Matteo Sposato, Giuseppe Palladino, Alessandro Vescogni 等
2021-10-14T18:57:05Z
置信度 0.70
-
Uncovering and understanding the chemical and fossil record of ancient life is crucial to understanding how life arose, evolved, and distributed itself across Earth. Potential signs of ancient life, however, are often challenging to establish as definitively b…
crossref
Andrew Gangidine, Jeff R. Havig, David A. Fike, Clive Jones 等
2019-12-20T09:49:37Z
置信度 0.70
-
crossref
Jinpeng Yang, Zhixiong Jiao, Zhenrun Zhan, Xu Tang 等
2024-04-05T18:38:22Z
置信度 0.70
-
crossref
Dániel Apai, Tom D. Milster, Dae Wook Kim, Alex Bixel 等
2019-07-30T10:13:31Z
置信度 0.70
-
Non-traditional trace metals are increasingly utilized to evaluate potential microbial processes in the search for evidence of ancient life. Recent investigations of modern terrestrial hot spring silica deposits (sinter), as analogs for early life on Earth or …
crossref
Michael C. Rowe, Tak Kunihiro, Ryoji Tanaka, Nghiem V. Dao 等
2026-03-14T02:48:06Z
置信度 0.70
-
Thermococcales, a major order of hyperthermophilic archaea inhabiting iron- and sulfur-rich anaerobic parts of hydrothermal deep-sea vents, are known to induce the formation of iron phosphates, greigite (Fe 3 S 4 ) and abundant quantities of pyrite (FeS 2 ), i…
crossref
Chloé Truong, Sylvain Bernard, Pierre Le Pape, Guillaume Morin 等
2023-05-25T04:18:28Z
置信度 0.70
-
Abstract The icy moons of Saturn and Jupiter are high priority locations in which to search for biomarkers of life elsewhere in our solar system. In particular, the ice plumes that jet out through the ice surface at Enceladus provide an enticing opportunity to…
crossref
Richard A. Mathies, James S. New, Matin Golozar, Anna L. Butterworth
2021-08-13T12:03:50Z
置信度 0.70
-
crossref
Sebastián Moschen, Janet Higgins, Julio A. Di Rienzo, Ruth A. Heinz 等
2016-06-06T04:47:36Z
置信度 0.70
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Background: The overlapping clinical presentations of limb-girdle muscular dystrophy (LGMD) and idiopathic inflammatory myopathy (IIM) make clinical diagnosis challenging. This study provides a comprehensive evaluation of the distributions and characteristics …
europepmc
Wen-Chi Hsu, Yu-Ching Lin, Hai-Hua Chuang, Kun-Yun Yeh 等
2021
置信度 0.80
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We describe the design of an instrument, the OxR (for Oxygen Release), for the enzymatically specific and non-enzymatic detection and quantification of the reactive oxidant species (ROS), superoxide radicals (O2•−), and peroxides (O22−, e.g., H2O2) on the surf…
crossref
Christos D. Georgiou, Christopher P. McKay, Richard C. Quinn, Electra Kalaitzopoulou 等
2019-08-27T11:13:30Z
置信度 0.70
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Methane (CH 4 ) is a simple molecule that, due to its radiative forcing, wields an outsized impact on planetary heat balance. Methane is formed by diverse abiotic pathways across a range of pressures and temperatures. Biological methanogenesis for anaerobic re…
crossref
Jennifer B. Glass, Sarah M. Hörst
2025-02-04T15:00:59Z
置信度 0.70
-
Multiple myeloma (MM) patients have highly variable overallsurvival (OS) ranging from few weeks to more than ten years. Discovering an early biosignature to stratify short-term from long-term survivors offers the prospect of treating at-risk patients. Machine …
crossref
Muhammad Kashif, Yijie Zhou, Vincent Luong, Katarina Uttervall 等
2023-12-01T15:36:34Z
置信度 0.70
-
pubmed
Cillian T. Forde, Surya K. Karri, Adam M. H. Young, Christopher S. Ogilvy 等
2013-07-15T14:16:26Z
置信度 0.82
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ABSTRACT The majority of potentially habitable planets detected to date are likely quite different to Earth, for example, being larger in radius and mass, differing rotation rates and with host star spectra unlike the Sun. Therefore, the first alien life detec…
crossref
Arwen E Nicholson, Nathan J Mayne
2026-07-09T11:57:14Z
置信度 0.70
-
crossref
Pengyu Zheng, Yong Yi, Ye Luo
2025-03-12T13:52:43Z
置信度 0.70
-
crossref
Svetlana Shkolyar, Evan J. Eshelman, Jack D. Farmer, David Hamilton 等
2018-04-06T10:00:05Z
置信度 0.70
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crossref
Bernard J. Rauscher, Edgar R. Canavan, Samuel H. Moseley, John E. Sadleir 等
2016-08-17T22:31:35Z
置信度 0.70
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crossref
Jesper Lindahl, Miranda Stiernborg, Filip Ventorp, Klara Suneson 等
2025-04-09T09:48:19Z
置信度 0.70
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crossref
Andrew Szentgyorgyi, David J. Erskine, Philip S. Muirhead, Andrew M. Vanderburg
2018-07-06T16:41:34Z
置信度 0.70
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crossref
Monique von Molendorff, Novel Chegou, Tracey Jooste
2024-03-01T12:12:11Z
置信度 0.70
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Abstract e Eridani , the fifth-closest Sun-like star, hosts at least three planets and could possibly harbor more. However, the veracity of the planet candidates in the system and its full planetary architecture remain unknown. Here we analyze the planetary ar…
crossref
Ritvik Basant, Jeremy Dietrich, Dániel Apai
2022-06-16T07:50:46Z
置信度 0.70
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Abstract Background and rationale As an adjunct to coronary intervention, the Liquid Biopsy System (LBS, PlaqueTec, UK) enables accurate intracoronary blood sampling at discrete sites simultaneously. We investigated variation between local coronary and remote …
europepmc
Diane Proudfoot, Bruna Gigante, Nick E.J. West, Stephen P. Hoole 等
2023
置信度 0.80
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crossref
M.R.M. Izawa, Neil R. Banerjee, G.R. Osinski, R.L. Flemming 等
2011-07-18T16:00:57Z
置信度 0.70
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Background: Several host inflammatory markers have been proposed as biomarkers for diagnosis and treatment response in Tuberculosis (TB), but few studies compare their utility in different demographic, ethnic, and TB endemic settings. Methods: Fifty-four host …
europepmc
Bih H. Chendi, Candice I. Snyders, Kristian Tonby, Synne Jenum 等
2021
置信度 0.80
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Abstract Major Depressive Disorder (MDD) has heterogeneous manifestations, leading to difficulties in predicting the evolution of the disease and in patient's follow-up. We aimed to develop a machine learning algorithm that identifies a biosignature to provide…
europepmc
Nicolas Ricka, Gauthier Pellegrin, Denis A. Fompeyrine, Bertrand Lahutte 等
2023
置信度 0.80
-
crossref
Laura K. Baumgartner, Christophe Dupraz, Daniel H. Buckley, John R. Spear 等
2009-12-07T11:47:12Z
置信度 0.70
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Abstract Major depressive disorder (MDD) is a leading cause of morbidity with a lifetime prevalence of 10%. There is increasing evidence suggesting synaptic dysfunction and impaired integrity of certain brain circuits in MDD. Here we investigate the cerebrospi…
crossref
MHD Rami Al Shweiki, Patrick Oeckl, Petra Steinacker, Peggy Barschke 等
2020-05-19T05:45:12Z
置信度 0.70
-
Jezero Crater on Mars is a paleolacustrine environment where Mg-carbonates may host evidence of ancient life. To elucidate the environmental and mineralogical controls on biosignature preservation, we examined samples from five terrestrial analogs: Lake Salda …
crossref
Teanna M. Burnie, Ian M. Power, Carlos Paulo, Hülya Alçiçek 等
2023-03-21T15:43:40Z
置信度 0.70
-
crossref
Tereza Varnali, Howell G.M. Edwards
2013-05-02T16:56:13Z
置信度 0.70
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<p>The presence of extinct or extant life on extraterrestrial Solar System Bodies is a high priority topic in space science. Reliable detection of signatures of life poses many challenges, including the requirement for flight-capable instrumentat…
crossref
Nikita Jennifer Boeren, Kristina Anna Kipfer, Niels Frank Willem Ligterink, Coenraad Pieter de Koning 等
2022-03-28T07:47:53Z
置信度 0.70
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Protein aggregation cardiomyopathy is a life-threatening manifestation of a multisystem disorder caused by the exchange mutation in the gene encoding the human small heat shock protein αB-crystallin (hR120GCryAB). Genetic studies in mice have established cardi…
crossref
Namakkal S. Rajasekaran, Matthew A. Firpo, Brett A. Milash, Robert B. Weiss 等
2008-07-16T03:34:27Z
置信度 0.70
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crossref
Dilini Rathnayake, Thashi Chang, Preethi Udagama
2019-04-06T07:02:41Z
置信度 0.70
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crossref
Anthony T. Wong, William A. Hoey, Maxwell Martin, Carlos Soares 等
2022-01-03T21:30:33Z
置信度 0.70
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crossref
David Blake, Richard Walroth, Thomas Bristow, Philippe Sarrazin 等
2021-05-27T17:47:49Z
置信度 0.70
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crossref
C. Kuslich, T. L. Pawlowski, T. Deng, T. Tinder 等
2017-02-24T02:41:10Z
置信度 0.70
-
Abstract Serpentinization is a geological process involving the interaction of water and ultramafic rock, the chemical byproducts of which can serve as an energy source for microbial communities. Although serpentinite systems are known to host active microbial…
crossref
Jon Lima-Zaloumis, Anna Neubeck, Magnus Ivarsson, Maitrayee Bose 等
2022-10-07T12:05:14Z
置信度 0.70
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Abstract Saturn's Moon Titan receives volatiles into the top of its atmosphere—including atomic oxygen—sourced from cryovolcanoes on Enceladus. Similar types of atmosphere exchange from one body to another, such as O 2 and O 3 sourced from TRAPPIST‐1 d, could …
crossref
Ryan C. Felton, Sandra T. Bastelberger, Kathleen E. Mandt, Adrienn Luspay‐Kuti 等
2022-03-14T16:46:15Z
置信度 0.70
-
crossref
Andreas Schuh, Michael Morimoto, Piotr Kaszuba, Kevin Hammond 等
2023-11-14T18:48:28Z
置信度 0.70
-
europepmc
Georgios V. Thomaidis, Konstantinos Papadimitriou, Sotirios Michos, Evangelos Chartampilas 等
2023
置信度 0.80