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With advances in commercial space launch capabilities and reduced costs to orbit, humans may arrive on Mars within a decade. Both to preserve any signs of past (and extant) martian life and to protect the health of human crews (and Earth's biosphere), it will …
pubmed
Glass B, Bergman D, Parro V, Kobayashi L 等
2023
置信度 0.82
-
europepmc
2024
置信度 0.80
-
europepmc
2022
置信度 0.80
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europepmc
2025
置信度 0.80
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europepmc
2026
置信度 0.80
-
A continuing frustration for origin of life scientists is that abiotic and, by extension, pre-biotic attempts to develop self-sustaining, evolving molecular systems tend to produce more dead-end substances than macromolecular products with the necessary potent…
europepmc
2025
置信度 0.80
-
Sources and sinks of methane within an advanced serpentinization-influenced system were investigated at the Coast Range Ophiolite Microbial Observatory (CROMO) in Lower Lake, California. Subsurface water-rock reactions at CROMO contribute to unique, high pH gr…
europepmc
2025
置信度 0.80
-
Abstract Suicide is the second leading cause of death for American adolescents and young adults and is transdiagnostic. Suicide risk is impacted by genetic and both distal and proximal environmental factors, particularly stress exposures. This review encompass…
europepmc
Ran Barzilay, Katherin Sudol, Nikolaos P. Daskalakis, Maura B. Dupont 等
2026
置信度 0.80
-
europepmc
2024
置信度 0.80
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europepmc
2026
置信度 0.80
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europepmc
2024
置信度 0.80
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europepmc
2025
置信度 0.80
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europepmc
2025
置信度 0.80
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europepmc
2025
置信度 0.80
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europepmc
2024
置信度 0.80
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europepmc
2024
置信度 0.80
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europepmc
2024
置信度 0.80
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Abstract The objective of this study is to validate a placebo pill response predictive model—a biosignature —that classifies chronic pain patients into placebo responders ( predicted-PTxResp ) and nonresponders ( predicted-PTxNonR ) and test whether it can dis…
europepmc
Etienne Vachon-Presseau, Taha B. Abdullah, Sara E. Berger, Lejian Huang 等
2021-08-25T21:02:50Z
置信度 0.80
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Life emerged on Earth in an ultramafic world under anaerobic conditions and conditioned by particular environmental characteristics for which no record remains. Molecular clocks suggest that the Last Universal Common Ancestor, LUCA, lived in a well-established…
europepmc
2025
置信度 0.80
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europepmc
2025
置信度 0.80
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europepmc
2024
置信度 0.80
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europepmc
2024
置信度 0.80
-
The long-term presence of humans in space depends on reducing reliance on Earth's resupply of materials and resources. In situ resource utilization (ISRU) represents a sustainable approach to support human activities in space by converting local materials into…
europepmc
2026
置信度 0.80
-
europepmc
2024
置信度 0.80
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europepmc
2024
置信度 0.80
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europepmc
2025
置信度 0.80
-
Homochirality is a generic and unique property of all biochemical life and it is considered a universal and agnostic biosignature. Upon interaction with unpolarized light, homochirality induces fractional circular polarization in the light that is scattered fr…
pubmed
Patty CHL, Pommerol A, Kühn JG, Demory BO 等
2022
置信度 0.82
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europepmc
2024
置信度 0.80
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europepmc
2024
置信度 0.80
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europepmc
2025
置信度 0.80
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europepmc
2024
置信度 0.80
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europepmc
2024
置信度 0.80
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europepmc
2026
置信度 0.80
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europepmc
2024
置信度 0.80
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europepmc
2026
置信度 0.80
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europepmc
2026
置信度 0.80
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europepmc
2025
置信度 0.80
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europepmc
2024
置信度 0.80
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europepmc
2024
置信度 0.80
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europepmc
2026
置信度 0.80
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europepmc
2024
置信度 0.80
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europepmc
2025
置信度 0.80
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europepmc
2024
置信度 0.80
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europepmc
2024
置信度 0.80
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europepmc
2023
置信度 0.80
-
Low-molecular-mass organic chemicals are widely discussed as potential indicators of life in extraterrestrial habitats. However, demarcation lines between biotic chemicals and abiotic chemicals have been difficult to define. Here, we have analyzed the potentia…
pubmed
Abrosimov R, Moosmann B
2024
置信度 0.82
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europepmc
2025
置信度 0.80
-
europepmc
2026
置信度 0.80
-
The NASA Mars 2020 Perseverance rover is currently exploring Jezero crater, a Noachian-Hesperian locality that once hosted a delta-lake system with high habitability and biosignature preservation potential. Perseverance conducts detailed appraisals of rock tar…
pubmed
Hickman-Lewis K, Moore KR, Hollis JJR, Tuite ML 等
2022
置信度 0.82
-
europepmc
2024
置信度 0.80
-
europepmc
2025
置信度 0.80
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europepmc
2025
置信度 0.80
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europepmc
2024
置信度 0.80
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europepmc
2024
置信度 0.80
-
# ONTOLOGIA MONOLITICA DI ATLANTIDE# Autore: Sistema AI esperto del Paradigma Sardo-Corso-Atlantideo# Fonte: Paradigma Sardo Corso Atlantideo (PSCA) di Luigi Usai# Data: 17 Aprile 2026# Licenza: CC BY-SA 4.0# Descrizione: Ontologia completa per il concetto di …
datacite
Usai, Luigi
2026
置信度 0.66
-
# ONTOLOGIA MONOLITICA DI ATLANTIDE# Autore: Sistema AI esperto del Paradigma Sardo-Corso-Atlantideo# Fonte: Paradigma Sardo Corso Atlantideo (PSCA) di Luigi Usai# Data: 17 Aprile 2026# Licenza: CC BY-SA 4.0# Descrizione: Ontologia completa per il concetto di …
datacite
Usai, Luigi
2026
置信度 0.66
-
This equation establishes the absolute sovereignty of ordered will across the entire conical fabric of the cosmos: $$\mathcal{L}_{Vortex}^{(1155)} = \oint_{\mathcal{V}_{cone}} \left[ \mathcal{G}_{\Omega} \left( \Phi_{Spiral}^{\mu\nu} \cdot \frac{\partial \math…
datacite
HAMZAH, SEYED RASOUL
2026
置信度 0.66
-
This equation establishes the absolute sovereignty of ordered will across the entire conical fabric of the cosmos: $$\mathcal{L}_{Vortex}^{(1155)} = \oint_{\mathcal{V}_{cone}} \left[ \mathcal{G}_{\Omega} \left( \Phi_{Spiral}^{\mu\nu} \cdot \frac{\partial \math…
datacite
HAMZAH, SEYED RASOUL
2026
置信度 0.66
-
Microbial motility is a reliable biosignature of extant life, serving as a measurable indicator of active metabolism, structural integrity, and environmental responsiveness — a relationship recognized since Leeuwenhoek’s earliest observations and regularly use…
datacite
Snyder, Carl, Santos, Berke, Sumrall, Louis, Nadeau, Jay
2026
置信度 0.66
FOS: Biological sciencesFOS: Environmental biotechnologyFOS: Other natural sciencesHolographic microscopyMicrobial taxis
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This equation establishes the absolute sovereignty of ordered will across the entire conical fabric of the cosmos: $$\mathcal{L}_{Vortex}^{(1155)} = \oint_{\mathcal{V}_{cone}} \left[ \mathcal{G}_{\Omega} \left( \Phi_{Spiral}^{\mu\nu} \cdot \frac{\partial \math…
datacite
HAMZAH, SEYED RASOUL
2026
置信度 0.66
-
crossref
Catheryn H. Ryan, Mariek E. Schmidt, Gordon R. Osinski, Erica A. Massey
2024-03-11T23:27:55Z
置信度 0.70
-
Abstract Basaltic hydrovolcanic environments on Earth produce abundant glass (sideromelane), which readily alters and acts as an important source of chemical energy for lithotrophic microorganisms; as such, these sites are significant for potential origins-of-…
crossref
Catheryn H. Ryan, Mariek E. Schmidt, Gordon R. Osinski, Erica A. Massey
2024-01-27T00:51:31Z
置信度 0.70
-
Future missions to icy ocean worlds (OW) such as Europa and Enceladus will evaluate the habitability of, and search for, potential biosignatures from these worlds. These missions will benefit substantially from autonomous science methods to process high volume…
crossref
Lily A Clough, Victoria Da Poian, Jonathan D Major, Lauren M Seyler 等
2024-08-12T15:42:29Z
置信度 0.70
-
crossref
Chester E. Harman, Shawn Domagal-Goldman
2018-06-14T05:12:51Z
置信度 0.70
-
Detecting biosignature gases on exoplanet atmosphere with near-future space telescopes is one of the most promising methods of detecting life beyond Earth. However, only a handful of biosignature gases are discussed today, and some can also be made by non-livi…
crossref
Zhuchang Zhan
2019-06-28T14:34:06Z
置信度 0.70
-
ABSTRACT Carbonate rocks retain a well preserved record of biologically associated structures at the outcrop to millimeter scale; however, microscale features such as cellular fossils are rarely represented. The lack of microscale textural information in ancie…
crossref
Jon Lima-Zaloumis, Jack D. Farmer, Elizabeth Trembath-Reichert
2024-04-09T16:56:30Z
置信度 0.70
-
Abstract To assess whether life existed on Mars, it is crucial to identify geochemical biosignatures that are relevant to specific Martian environments. In this paper, thermochemical modeling was used to investigate fluid chemistries and secondary minerals tha…
crossref
Simone Cogliati, Michael C. Macey
2024-02-01T10:30:59Z
置信度 0.70
-
ABSTRACT Due to their fast precipitation rate, sulfate evaporites represent excellent repositories of past life on Earth and potentially on other solid planets. Nevertheless, the preservation potential of biogenic remains can be compromised by extremely fast e…
europepmc
Luca Pellegrino, Marcello Natalicchio, Andrea Cotellucci, Andrea Genre 等
2024
置信度 0.80
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Introduction Multiple myeloma (MM) is a hematological malignancy of bone marrow plasma cells. Clinically, it is manifested with a spectrum of symptoms including focal/bone lesions, hypercalcemia, anemia, and renal dysfunction. Bone disease (BD) in MM is charac…
crossref
Muhammad Kashif, Niki Throumpari, Katarina Uttervall, Kristin Roseth Aass 等
2024-12-06T02:09:19Z
置信度 0.70
-
Abstract Telescope missions are currently being designed that will make direct imaging of habitable exoplanets possible in the near future, and studies are needed to quantify the detectability of biosignature features in the planet’s reflectance spectrum. We s…
crossref
Connor O. Metz, Nancy Y. Kiang, Geronimo L. Villanueva, M. N. Parenteau 等
2024-10-17T17:20:51Z
置信度 0.70
-
<div> Includes an expanded database with age, composition, setting, location, and structure name(s) for 45 volcanic fields; GIS data compatible with Esri ArcGIS Pro and Google Earth data of all 716 volcanic structures in database; map attribute table wit…
crossref
Catheryn H. Ryan, et al.
2023-12-14T17:59:11Z
置信度 0.70
-
europepmc
Pengfei Zhao, Dian Meng, Zunkai Hu, Yining Liang 等
2024
置信度 0.80
-
Abstract Introduction: Radiation therapy (RT) is a standard component of treatment for most patients with early-stage, hormone receptor-positive, invasive breast cancer (BC) following breast-conserving surgery (BCS). RT recommendations are primarily based on c…
crossref
Troy Bremer, Karuna Mittal, Chirag Shah, Frank Vicini 等
2024-05-02T07:13:49Z
置信度 0.70
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This paper presents developments in stationary phase coatings for microelectromechanical system gas chromatography (MEMS GC). Specifically, we present the coating of MEMS GC separation columns with a chiral stationary phase for the separation of amino acid ena…
crossref
Ryan C. Blase, Mark J. Libardoni, Christopher R. Glein, Kelly E. Miller 等
2024-05-07T17:35:58Z
置信度 0.70
-
Abstract Cardiopoiesis-primed human stem cells exert sustained benefit in treating heart failure despite limited retention following myocardial delivery. To assess potential paracrine contribution, the secretome of cardiopoiesis conditioned versus naïve human …
europepmc
Armin Garmany, D Kent Arrell, Satsuki Yamada, Ryounghoon Jeon 等
2024
置信度 0.80
-
crossref
Y. Zissiadis, K. Kirkham, A. Driver, L. Donnelly 等
2024-03-22T11:11:08Z
置信度 0.70
-
Abstract Schizophrenia (SCZ) is a chronic, severe, and complex psychiatric disorder that affects all aspects of personal functioning. While SCZ has a very strong biological component, there are still no objective diagnostic tests. Lately, special attention has…
europepmc
Makrina Karaglani, Agorastos Agorastos, Maria Panagopoulou, Eleni Parlapani 等
2024
置信度 0.80
-
Acute kidney injury is a common and complex complication that has high morality and the risk for chronic kidney disease among survivors. The accuracy of current AKI biomarkers can be affected by water retention and diuretics. Therefore, we aimed to identify a …
europepmc
Chih-Hsiang Chang, Cheng-Chia Lee, Yung-Chang Chen, Pei-Chun Fan 等
2024
置信度 0.80
-
crossref
Salahudeen Mirza, Alexandre Rubinstein, Christopher Busby, Rohit Jha 等
2024-04-29T05:38:46Z
置信度 0.70
-
Abstract The search for a second instance of life is one of the greatest problems of modern science. Outside of creating an artificial origin of life on Earth, the primary targets for the search for life are planets inside or outside the solar system. Realisti…
crossref
Harrison B. Smith, Lana Sinapayen
2026-04-09T12:28:28Z
置信度 0.70
-
crossref
Alexander M. Alyushin, Sergey V. Dvoryankin
2024-03-14T09:46:10Z
置信度 0.70
-
crossref
Gideon Yoffe, Fabian Klenner, Barak Sober, Yohai Kaspi 等
2026-05-11T09:11:27Z
置信度 0.70
-
Introduction: Studies display an increased cardiovascular (CV) risk in psoriasis, but the underlying mechanisms and prevention strategies are not known. We investigated platelet aggregation and the platelet transcriptome as one potential mechanism to explain C…
crossref
Kamelia Drenkova, Filipp Kazatsker, Matthew Muller, Florencia Schlamp 等
2024-11-14T12:06:52Z
置信度 0.70
-
crossref
Liza Das, Rama Walia, Anil Bhansali, Pinaki Dutta 等
2019-11-07T05:45:00Z
置信度 0.70
-
Abstract The first potential exoplanetary biosignature detections are likely to be ambiguous due to the potential for false positives: abiotic planetary processes that produce observables similar to those anticipated from a global biosphere. Here we propose a …
crossref
Michaela Leung, Edward W. Schwieterman, Mary N. Parenteau, Thomas J. Fauchez
2022-10-10T15:51:17Z
置信度 0.70
-
crossref
R.A. Rabinovitch, P.W. Whitworth, P.I. Borgen, K. Mittal 等
2024-09-27T18:43:07Z
置信度 0.70
-
Abstract Post-Acute COVID-19 Syndrome (PACS) has been defined as symptoms persisting after clearance of a COVID-19 infection. We have previously demonstrated that alterations in DNA methylation (DNAm) status persists in individuals who recovered from a COVID-1…
preprints
Frida Nikesjö, Shumaila Sayyab, Lovisa Karlsson, Eirini Apostolou 等
2022
置信度 0.74
-
Abstract. Methane-related carbonates from Hydrate Ridge typically show several macroscopically distinguishable phases, namely whitish aragonite, lucent aragonite, and gray micrite. The relationship of these phases to particular microorganisms or biogeochemical…
crossref
T. Leefmann, J. Bauermeister, A. Kronz, V. Liebetrau 等
2010-04-29T09:55:13Z
置信度 0.70
-
Abstract We propose the mathematical notion of information gain as a way of quantitatively assessing the value of biosignature missions. This makes it simple to determine how mission value depends on design parameters, prior knowledge and input assumptions. We…
crossref
Benjamin Fields, Sohom Gupta, McCullen Sandora
2023-08-04T08:47:52Z
置信度 0.70
-
crossref
Jack T. O'Malley-James, Lisa Kaltenegger
2018-09-11T16:44:06Z
置信度 0.70
-
ABSTRACT Upcoming biosignature searches focus on indirect indicators to infer the presence of life on other worlds. Aside from just signalling the presence of life, however, some biosignatures can contain information about the state that a planet’s biosphere h…
crossref
McCullen Sandora, Joseph Silk
2020-05-06T19:16:54Z
置信度 0.70
-
Abstract We deploy a newly generated set of geometric albedo spectral grids to examine the detectability of methane (CH 4 ) in the reflected-light spectrum of an Earth-like exoplanet at visible and near-infrared (NIR) wavelengths with a future exoplanet imagin…
crossref
Natasha Latouf, Michael D. Himes, Avi M. Mandell, Michael Dane Moore 等
2024-12-26T09:18:16Z
置信度 0.70
-
Abstract Several studies have identified biomarkers for tuberculosis (TB) diagnosis based on blood cell transcriptomics. Here, we instead studied epigenomics in the lung compartment by obtaining induced sputum from subjects included in a TB contact tracing. CD…
preprints
Jyotirmoy Das, Nina Idh, Isabelle Pehrson, Jakob Paues 等
2021
置信度 0.74
-
crossref
Saugata Datta, Jennifer G. Blank, Richard J. Leveille, Duane Moser
2016-10-20T18:06:14Z
置信度 0.70
-
Identifying organic molecular biosignatures for life is challenging. Most current analytical methods were developed on Earth sediments rich in total organic carbon (TOC), and these methods struggle when dilute organic matter is situated within reactive, minera…
crossref
Stephen Larter, Ben Tutolo, Christopher Tino, Lloyd Snowdon 等
2025-11-01T16:07:44Z
置信度 0.70
-
crossref
Alexander M. Alyushin, Mihail V. Alyushin, Sergej V. Dvoriankin
2022-06-14T16:41:43Z
置信度 0.70
-
crossref
Agnès Cousin, Olivier Gasnault, Valérie Mousset, Magali Bouyssou
2026-04-01T09:13:31Z
置信度 0.70
-
Following a brief summary of some fundamentals in carbonate sedimentology (sedimentary petrography) that highlights the significance of organic matter, some examples of biocrystals in carbonate grains/particles, such as bioclasts or ooids, are provided as an i…
crossref
Bruno Granier
2020-11-21T06:51:40Z
置信度 0.70
-
Abstract Future exoplanet direct imaging missions, such as HabEx and LUVOIR, will select target stars to maximize the number of Earth-like exoplanets that can have their atmospheric compositions characterized. Because one of these missions’ aims is to detect b…
crossref
Noah W. Tuchow, Jason T. Wright
2020-12-21T17:14:50Z
置信度 0.70
-
crossref
Aria Vitkova, Tuan H. Vu, James Lambert
2026-01-16T14:18:06Z
置信度 0.70