-
crossref
Jonathan Robert Belanich, Tuomas Oskari Kilpeläinen
2026-05-08T22:00:56Z
置信度 0.70
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crossref
Yoshihiro Ohmori
2026-04-23T05:45:04Z
置信度 0.70
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Shahwar Fatima Ansari, Mohamed Anas Mohamed, Anjela Davis Panattuparambil, Ajeesh Padinjattethil Sasidharan 等
2026-08-04T06:38:52Z
置信度 0.70
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Background Hepatocellular carcinoma (HCC) carries a dismal prognosis, yet the contribution of deubiquitination—an essential posttranslational regulator—to its progression remains poorly defined. Methods Single‐cell RNA‐seq profiles of 13 treatment‐naïve HCC tu…
crossref
Xuening Lv, Chaozhou Chen, Shuxian Zhang, Feng Liang 等
2026-01-08T06:15:37Z
置信度 0.70
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crossref
Zhengming Guo, Wei Zhang
2026-03-04T10:36:04Z
置信度 0.70
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crossref
Tiffany Tu, Alejandro Ochoa
2026-07-27T15:51:08Z
置信度 0.70
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crossref
Madison Caballero, Behrang Mahjani
2026-03-31T04:19:03Z
置信度 0.70
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Background Immune checkpoint blockade (ICB) has reshaped the approach to treating a broad spectrum of cancers, including bladder cancer (BLCA). However, a substantial fraction of BLCA patients still exhibit resistance despite high programmed death‐ligand 1(PD‐…
crossref
Zexun Deng, Yifan Li, Yuyong Shen, Ming Zhou
2026-04-06T11:52:11Z
置信度 0.70
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crossref
Tahani El Ayari, Najoua Trigui El Menif
2026-01-08T08:26:42Z
置信度 0.70
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Background. Our recent findings indicate that the rough form of the Mycobacterium abscessus complex (MABC) is associated with worse clinical outcomes compared to the smooth variant. The glycopeptidolipid (GPL) locus has been considered vital for this transitio…
crossref
Rajender Kumar, Clara Braian, Gabrielle Fröberg, Lina Davies Forsman 等
2026-05-06T15:15:42Z
置信度 0.70
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crossref
2026-02-17T21:06:04Z
置信度 0.70
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crossref
Haifang Dai, Yueheng Lv, Zihao Liu, Lijie Li
2026-01-03T07:17:24Z
置信度 0.70
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Objective Acute liver failure (ALF) is a severe condition with high mortality, where programmed cell death (PCD) plays a critical yet not fully understood role. This study aimed to identify key PCD‐related genes and explore their potential as biomarkers and th…
crossref
Guangli Liu, Huili Wu, Wenxiang Shi, Chenjie Qiu
2026-03-19T18:07:23Z
置信度 0.70
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crossref
2026-08-20T08:18:33Z
置信度 0.70
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Background Regular blood donation has been associated with lower cardiovascular risk in some studies, possibly through mechanisms involving reduced iron stores and oxidative stress. Objective The study investigated the association between blood donation freque…
crossref
Collince Odiwuor Ogolla, Bernard Guyah, Apollo O. Maima
2026-08-17T07:35:33Z
置信度 0.70
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crossref
Pavel Grasgruber, Martin Sebera
2026-02-06T22:05:48Z
置信度 0.70
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crossref
2026-02-17T21:06:04Z
置信度 0.70
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Flooding is a dominant constraint to rice production in lowland and floodplain ecosystems, where stress intensity, timing, and duration vary widely across agroecological zones. This review synthesizes current knowledge on flooding typologies affecting rice, in…
crossref
Abdoul-Razak Oumarou Mahamane, Junior S. Kamara, Moise Hubert Byiringiro, Alpha Sow
2026-04-03T09:05:47Z
置信度 0.70
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crossref
Lina Baz
2026-02-27T02:44:26Z
置信度 0.70
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The aggressive clinical course and limited treatment avenues for key bone malignancies, specifically osteosarcoma, Ewing′s sarcoma, and giant cell tumor of bone, are heavily dictated by their intricate tumor microenvironment (TME). To decode this cellular hete…
crossref
Lihe Pang, Ye Hua, Zhaofei Chen, Guoya Wu
2026-06-05T02:26:17Z
置信度 0.70
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Carcinoembryonic antigen–related cell adhesion molecule 1 (CEACAM1) is a multifunctional immunomodulatory protein involved in both immune activation and immune suppression across diverse cancer types. However, its biological significance and clinical relevance…
crossref
Ziqi Cao, Minjue Shan, Yadong Guo, Mengmei Zhang 等
2026-04-30T12:14:43Z
置信度 0.70
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Background Lung adenocarcinoma (LUAD), the most prevalent form of nonsmall cell lung cancer, poses significant diagnostic and therapeutic challenges due to its high mortality rate and complex pathophysiology. Despite advances in understanding LUAD’s molecular …
crossref
Yang Yang, Jun Yang, Deyang Liu, Xiaolu Fang 等
2026-03-31T09:38:08Z
置信度 0.70
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Background Osteosarcoma (OS) is characterized by a highly heterogeneous tumor microenvironment (TME) that frequently limits the efficacy of immunotherapy. Identifying molecular drivers of immune escape (IE) is essential for improving therapeutic outcomes. Meth…
crossref
Simin Liu, Hong Yan, Wei Ku, Guo Liu
2026-05-22T09:59:33Z
置信度 0.70
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crossref
Fei Shen, Shanshan Guo
2026-01-19T08:45:54Z
置信度 0.70
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crossref
Changyou Liu
2026-04-15T23:02:23Z
置信度 0.70
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crossref
2026-03-31T17:36:58Z
置信度 0.70
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Abstract The universe of possible nucleotide sequences expands combinatorially with sequence length, vastly exceeding the fraction sampled by real genomes. Yet genomic sequences exhibit reproducible compositional symmetries and recurrent structural motifs, ind…
crossref
Vitaly Kuryavyi
2026-07-04T05:45:10Z
置信度 0.70
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Abstract The domestic dog ( Canis lupus familiaris ) is a powerful model for genetic studies of complex disease, but canine genotype data are distributed across independent studies using incompatible genotyping platforms, genome builds, strand conventions, and…
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David M. Brundage
2026-04-16T06:05:17Z
置信度 0.70
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crossref
2026-04-01T10:03:02Z
置信度 0.70
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crossref
Mangi Kim
2026-07-08T07:19:40Z
置信度 0.70
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crossref
2026-02-02T06:57:19Z
置信度 0.70
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crossref
Xuping Zhou, Tao Peng, Jin Yu, Shanshan Dong 等
2025-07-26T15:03:31Z
置信度 0.70
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crossref
Tarikul Huda Mazumder, Arif Uddin
2026-06-06T04:06:00Z
置信度 0.70
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crossref
I.I. Ajayi, O.J. Olawuyi
2026-07-20T08:55:28Z
置信度 0.70
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crossref
Xihong Lan, Qiaoxing Liang, Jinhua He, Jiayi Wu 等
2026-01-22T16:35:32Z
置信度 0.70
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Abstract A computational kernel is defined by four properties: initialization from raw input, a fixed instruction set, a process table with memory organization, and inter-component signal dispatch. Here we show that the human genome satisfies all four. Applyin…
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Jasmine Levy
2026-04-15T21:10:15Z
置信度 0.70
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crossref
2026-03-04T11:34:21Z
置信度 0.70
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crossref
HONG-BEUM KIM, HEE-JEONG LEE, SANG-GON PARK
2026-03-02T09:20:15Z
置信度 0.70
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crossref
Sidra Khursheed, Muhammad Zeeshan Ahmed, Saira Khursheed, Zeeshan Mutahir 等
2026-02-13T06:40:24Z
置信度 0.70
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Mikhail Volodarskiy, Mikhail Rayko
2026-03-04T10:35:04Z
置信度 0.70
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crossref
2026-07-08T22:04:46Z
置信度 0.70
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Abstract Nitrogen fixing Rhizobia play an important role in legume growth and sustainable agriculture, and genome based analyses have become essential for understanding the genetic basis of their symbiotic traits and functional potential. Here, Rhizobium anhui…
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Volkan Eroğlu, Asiye Esra Eren Eroğlu, İhsan Yaşa
2026-05-07T01:05:28Z
置信度 0.70
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crossref
Corinna Langebrake, Miriam Liedvogel
2026-03-16T23:03:18Z
置信度 0.70
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crossref
2026-04-15T22:11:15Z
置信度 0.70
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This review explores how human genetic variation, from single nucleotide polymorphisms (SNPs) to structural alterations, continues to shape disease biology, including examples from population studies and SNP-mediated epigenetic regulation. The introduction out…
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Kamila Aliyeva, Nazaket Guseynova, Rena Mamedova
2026-06-21T21:13:11Z
置信度 0.70
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crossref
Khalid Shaikh, Rohit Thanki, Sejal Shah
2026-05-06T05:02:39Z
置信度 0.70
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crossref
Ayon Pal, Madhumita G. Chaki
2026-04-01T03:04:21Z
置信度 0.70
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crossref
Amy Garcia
2026-04-30T12:20:02Z
置信度 0.70
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S.K. Abdul Rahaman, Aman Sisodia, C.H. Ananda Kumar, Padmavathi Sakinala 等
2026-05-28T12:55:47Z
置信度 0.70
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Michael Mannstadt, Marc N. Wein
2026-03-27T09:12:57Z
置信度 0.70
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crossref
Aruna Pal, Keshav K. Singh
2026-08-21T10:09:42Z
置信度 0.70
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crossref
Jiali Cai, Ruiqi Wang, Yipeng Li, Wentao Gong 等
2026-06-22T16:26:58Z
置信度 0.70
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Abstract Splice-altering variants cause an estimated 15-30% of genetic diseases, yet computational tools lose accuracy outside the canonical GT-AG dinucleotides, leaving intronic variants of uncertain significance (VUS) hard to interpret. Here we present MetaS…
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Xiaoming Liu
2026-07-27T10:45:12Z
置信度 0.70
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crossref
Liz Simon
2026-05-26T11:10:16Z
置信度 0.70
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crossref
Aruna Pal, Keshav K. Singh
2026-08-21T10:09:42Z
置信度 0.70
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crossref
2008-05-23T14:37:37Z
置信度 0.70
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crossref
David K. Scoville, Christopher M. Schaupp, Terrance J. Kavanagh
2024-08-12T18:09:43Z
置信度 0.70
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crossref
Sheel Yadav, Wanchha Maurya, Ratna Kumari, Sandhya Sharma 等
2026-06-04T01:13:43Z
置信度 0.70
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crossref
Surajit Pathak, Antara Banerjee
2026-04-03T20:10:21Z
置信度 0.70
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crossref
Sirikul Thummajitsakul, Rattiporn Kosuwin, Sunisa Krainara, Wittaya Kaewsri 等
2026-08-29T15:32:21Z
置信度 0.70
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crossref
2026-02-04T15:59:34Z
置信度 0.70
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crossref
Muhammad Atif, Hammad Ahmed Abbasi, Muhammad Naveed Anjum
2026-07-24T07:01:44Z
置信度 0.70
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crossref
Joshua Hack, Mohammad Nazim
2026-02-28T07:52:05Z
置信度 0.70
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crossref
Ryo Ootsuki
2026-08-11T03:35:13Z
置信度 0.70
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crossref
Qinqin Sun, Jinqing Xiao, Jinfeng Huo
2026-04-01T06:09:11Z
置信度 0.70
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crossref
Congcong Wang, Peng Wan, Xiaoyan Liu, Yan Yao 等
2026-06-03T09:18:19Z
置信度 0.70
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crossref
Bevin Nishanth. J, Kishore Vijayakumar, M. Sandhiya, Suji Somasundaram
2026-07-27T15:49:52Z
置信度 0.70
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Background Cuprotosis is an emerging form of copper‐dependent programmed cell death, while low‐grade gliomas (LGGs) represent a common subtype of primary brain tumors. Methods Datasets from The Cancer Genome Atlas and TargetScan were utilized to identify cupro…
crossref
Zhaoliang Xue, Zhengfei Song, Lianjie Mo, Shuxu Yang
2026-01-29T15:14:45Z
置信度 0.70
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crossref
Hamid Sahebalam, Mohsen Gholizadeh
2026-04-06T06:37:20Z
置信度 0.70
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Osteosarcoma is a highly aggressive bone tumor with a complex tumor microenvironment (TME) that contributes to its progression and therapeutic resistance. In this study, we integrated single‐cell RNA sequencing (scRNA‐seq) and bulk RNA‐seq datasets to characte…
crossref
Jiamiao Li, Wei Wang, Li Li, Kangjun Yu
2026-03-09T05:37:05Z
置信度 0.70
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crossref
Ben R. Hopkins, Artyom Kopp
2026-03-11T15:09:41Z
置信度 0.70
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crossref
Xiaoyan Ma, Yanqiu Liu, Xia Xu, Hua Wang 等
2026-05-27T04:07:47Z
置信度 0.70
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crossref
Tomasz Grzyb, Justyna Szulc
2026-06-24T04:05:18Z
置信度 0.70
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crossref
Nikita Bindal, Sujata Mohanty
2026-05-02T02:28:31Z
置信度 0.70
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Background Yogurt is reported to maintain the balance of gut microbiota and prevent disease, but the causal relationship remains unclear. Methods We selected data from UK Biobank and MiBioGen to perform Mendelian randomization analysis. MR Egger, inverse varia…
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Mengqi Yang, Liping Wang, Peng Zhou, Jiazeng Xia
2026-03-08T19:41:09Z
置信度 0.70
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Qingmei Wang, Fei Lin, Xueying Wang, Weiqun Guan 等
2026-07-08T03:09:00Z
置信度 0.70
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crossref
Wenjia Li, Jingkun Zhang, Yongxin Xu, Wenjing Li 等
2026-02-13T08:13:24Z
置信度 0.70
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Medicinal plants serve as invaluable sources of bioactive compounds, yet the molecular basis of their secondary metabolite biosynthesis remains largely unexplored. Piper chaba Hunter, an important but understudied member of the Piperaceae family, is known for …
crossref
Deeksha Singh, Shivangi Mathur, Rajiv Ranjan
2026-06-27T09:34:16Z
置信度 0.70
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Shalini Majumder, Ekarsi Lodh, Tiasha De, Tapan Chowdhury
2026-04-24T11:33:58Z
置信度 0.70
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Background Hepatocellular carcinoma (HCC) ranks among the world′s most lethal cancers, with the majority of cases diagnosed at advanced stages. Accurate prognostic assessment is therefore essential for HCC management. This study utilized DNA methylation (MDGs)…
crossref
Geyang Hu, Liang Zhou, Jie Zhang
2026-01-27T14:42:57Z
置信度 0.70
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Background Health developments are based on family‐specific health traditions, which play a central role as a foundation of individuals’ growth and development in Southeast Asia. Families can influence disease susceptibility and promote well‐being by encouragi…
crossref
Robiul Islam Akash, Mohammad Anamul Haque, Nahid Sultana, Mohammad Ohid Ullah
2026-05-30T10:23:21Z
置信度 0.70
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crossref
Temesgen Begna, Werkissa Yali, Temesgen Teressa, Hayilu Gichile
2026-07-09T13:03:32Z
置信度 0.70
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crossref
Oliver Brown, Andressa Oliveira de Lima, Yvonne Drechsler, R. David Hawkins
2026-02-23T16:18:56Z
置信度 0.70
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crossref
Dherya Guleria, Ravi Raj Pal, Navjot Kaur Sandhu
2026-06-04T15:28:21Z
置信度 0.70
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crossref
SAMUELE GRAZIANO, BARBARA HÖLLBACHER, ULRICH H. WEIDLE
2026-06-29T14:05:16Z
置信度 0.70
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crossref
Brown Beckley, Vincent Amarh
2026-02-06T01:13:59Z
置信度 0.70
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crossref
2008-05-23T14:37:37Z
置信度 0.70
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Reply to 'Genome engineering for conservation might be a game changer but only with the incorporation of Indigenous voices' in Nature Reviews Biodiversity
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Stephen D. Turner
2026-01-12T11:00:21Z
置信度 0.70
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Abstract Background Mango ( Mangifera indica L.) is a globally significant fruit over the world. The precise identification of germplasm resources is of great significance for the breeding of new mango cultivars. Traditional methods based on phenotypic charact…
crossref
Feng Liu, Chunyuan Wu, Jingping Liu, Quansheng Yao 等
2026-07-17T23:03:56Z
置信度 0.70
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crossref
2026-07-13T11:25:00Z
置信度 0.70
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crossref
Marcelo A. Marti
2026-08-21T14:23:04Z
置信度 0.70
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crossref
Santosh Sushma Pinninti, Suman Govindaraju, Himaja Nallagatla
2025-12-05T23:36:40Z
置信度 0.70
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crossref
Devavarapu Kasi Viswa Prasad, Imran Ali Khan
2025-12-05T23:36:40Z
置信度 0.70
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crossref
MEHEK SUMAR, TIMOTHY P. FLEMING, ROSS M. BREMNER, NARENDRA V. SANKPAL
2026-06-29T14:05:16Z
置信度 0.70
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crossref
Nguyen Quoc Khanh Le
2026-03-23T07:20:22Z
置信度 0.70
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crossref
Anu Shibi Anilkumar, Ramakrishnan Veerabathiran
2026-07-08T08:23:58Z
置信度 0.70
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Abstract Background Transcript-resolved models of RNA enable functional interrogation of RNA biology by linking processing, structure, localisation, and regulatory interactions to specific RNA molecules. Across coding and noncoding transcriptomes, such models …
crossref
Natalia Benova, Rene Kuklinkova, Emanuela Ibenye, James R. Boyne 等
2026-08-11T01:04:06Z
置信度 0.70
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crossref
2026-07-02T12:56:19Z
置信度 0.70
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crossref
Poonam Kumari, Alka Rana, Kushal Thakur, Kumari Ruchika 等
2026-03-10T08:14:02Z
置信度 0.70
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crossref
2026-07-02T12:56:18Z
置信度 0.70