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• Andampindambrahmandam (APB): Universal Research Database Engine for Cross-Scale Physics and Omics v 0.8
  Andampindambrahmandam (APB)Genome-Based Quantum Computing Through Particle Language ModelsCopyright © 2026 Coding Photon Pvt Ltd. All Rights Reserved. Published for academic visibility and collaboration inquiries only. Commercial use requires written permissio…
  datacite Sankaramanchi, Raghavendra Rao 2026 置信度 0.66
• AI-Driven Diagnostics: Regulatory Challenges and Strategic Implications for Medical Device Manufacturers
  Artificial intelligence is increasingly used in medical diagnostics, especially in radiology, laboratory medicine, dermatology, and genomics, where it promises greater efficiency and improved diagnostic quality. At the same time, AI creates specific risks, par…
  datacite Amir Al-Munajjed, Maurice Ehlers 2026 置信度 0.66 Medical devicesDigital healthOther health sciences not elsewhere classified
• AI-Driven Diagnostics: Regulatory Challenges and Strategic Implications for Medical Device Manufacturers
  Artificial intelligence is increasingly used in medical diagnostics, especially in radiology, laboratory medicine, dermatology, and genomics, where it promises greater efficiency and improved diagnostic quality. At the same time, AI creates specific risks, par…
  datacite Amir Al-Munajjed, Maurice Ehlers 2026 置信度 0.66 Medical devicesDigital healthOther health sciences not elsewhere classified
• Cell Maps for Artificial Intelligence - U2OS Cell Map
  <h3>Description</h3> <p>This dataset is the U2OS Cell Map Release of Cell Maps for Artificial Intelligence (CM4AI; CM4AI.org), the Functional Genomics Grand Challenge in the NIH Bridge2AI program. It provides an AI-ready, provenance-tracked r…
  datacite Leah V. Schaffer, Mengzhou Hu, Gege Qian, Kyung-Mee Moon 等 2026 置信度 0.66 Medicine, Health and Life SciencesAIaffinity purificationAP-MSartificial intelligence
• Interdisciplinary approaches in modern zoology
  Modern zoology has undergone a profound disciplinary transformation: questions that were once the exclusive domain ofnatural history and field biology now draw equally on molecular genetics, computational data science, physics-inspiredmodelling, social science…
  datacite Dr. Felix Petrov, Dr. Clara Nowak, Dr. Lukas Horvath 2026 置信度 0.66 interdisciplinary research; modern zoology; conservation social science; landscape genomics; One Health; natural capital; bibliometrics; research collaboration; disciplinary integration; Horizon Europe
• Interdisciplinary approaches in modern zoology
  Modern zoology has undergone a profound disciplinary transformation: questions that were once the exclusive domain ofnatural history and field biology now draw equally on molecular genetics, computational data science, physics-inspiredmodelling, social science…
  datacite Dr. Felix Petrov, Dr. Clara Nowak, Dr. Lukas Horvath 2026 置信度 0.66 interdisciplinary research; modern zoology; conservation social science; landscape genomics; One Health; natural capital; bibliometrics; research collaboration; disciplinary integration; Horizon Europe
• Data and code from: The Great Dividing Range as a driver of genetic divergence in a low-dispersing dragonfly
  Across complex landscapes, genetic structure can arise through a combination of geographic, ecological, and historical processes. In mountain systems, isolation by distance (IBD), environment (IBE), and resistance (IBR) represent three such mechanisms, but are…
  datacite Goodman, Aaron, Tolman, Ethan, Beatty, Christopher, Blair, Mary 等 2026 置信度 0.66 FOS: Biological sciencesFOS: Natural sciencesGenomicsEntomologyPopulation genetics
• Comparative Genomic Insights into Pangenome Diversity and Functional Adaptation of Akkermansia and Faecalibacterium as Gut-Associated Next-Generation Probiotics: A Systematic Review
  This systematic review aimed to comprehensively synthesize current evidence and how comparative genomics has been applied to characterize pangenome diversity and functional adaptation, in the gut-associated next-generation probiotics (NGP) genera Akkermansia a…
  datacite La Arlan, Riris Delima Purba, Rani Dwi Lestari, Fami Israyusnita 等 2026 置信度 0.66 Medicine and Health SciencesLife SciencesAkkermansia muciniphila comparative pangenomics Faecalibacterium prausnitzii functional genomic gut microbiota microbiome therapeutics whole-genome sequencing.systematic review
• Supplementary Data and Scripts for "How many are you? Open data and bioinformatics reveal species misidentification and potential introgression in Chordodes (Phylum Nematomorpha)"
  Supplementary data and scripts for "Open data and bioinformatics reveal species misidentification in Chordodes (Phylum Nematomorpha)". The same scripts and data have been used for the presentation "Open data for understanding potential issues in species identi…
  datacite De Vivo, Mattia 2026 置信度 0.66 BioinformaticsPhylogenomicsNematomorpha
• Supplementary Data and Scripts for "How many are you? Open data and bioinformatics reveal species misidentification and potential introgression in Chordodes (Phylum Nematomorpha)"
  Supplementary data and scripts for "Open data and bioinformatics reveal species misidentification in Chordodes (Phylum Nematomorpha)". The same scripts and data have been used for the presentation "Open data for understanding potential issues in species identi…
  datacite De Vivo, Mattia 2026 置信度 0.66 BioinformaticsPhylogenomicsNematomorpha
• Chronic inflammation and multiple dimensions of aging among women in the Philippines
  Chronic systemic inflammation is a robust predictor of all-cause mortality, as well as age-related increases in cardiometabolic diseases and declines in physical and cognitive abilities [1, 2]. Concentrations of inflammatory biomarkers typically increase with …
  datacite Thomas McDade 2025 置信度 0.66 Medicine and Health Sciences
• Updated risk stratification for lower-grade (grade 2 and 3) IDH-mutant diffuse gliomas
  Background: The definition of a "low-grade, high-risk diffuse glioma" was established decades ago and is based largely on clinical factors such as age, tumor size, histology and qualitative extent of tumor resection. Our understanding of tumor genomics and pro…
  datacite Philipp Karschnia, Nico Teske, Jörg-Christian Tonn, Martin van den Bent 等 2026 置信度 0.66 Medical SciencesNeurosciencesMedicine and Health SciencesMedical SpecialtiesOncology
• Improved Iso-Seq-based genome annotations for Australian wild rice species O. rufipogon and O. meridionalis
  This dataset contains improved genome annotation files generated for two Australian wild rice species, Oryza rufipogon and Oryza meridionalis. The annotations were generated by integrating existing reference genome annotations with Iso-Seq-derived transcript m…
  datacite Nurmansyah, Furtado, Agnelo, Henry, Robert 2026 置信度 0.66
• Improved Iso-Seq-based genome annotations for Australian wild rice species O. rufipogon and O. meridionalis
  This dataset contains improved genome annotation files generated for two Australian wild rice species, Oryza rufipogon and Oryza meridionalis. The annotations were generated by integrating existing reference genome annotations with Iso-Seq-derived transcript m…
  datacite Nurmansyah, Furtado, Agnelo, Henry, Robert 2026 置信度 0.66
• AI Meets Multiomics Sequencing: The Technology Ecosystem for Precision Medicine
  This paper examines the convergence of artificial intelligence, multiomics sequencing, digital health technologies, and standards-based governance within the emerging field of precision medicine. It presents the Nebusis® Precision Care System™, a healthcare ec…
  datacite Alvarado Martinez, Celso 2025 置信度 0.66 Precision MedicinePrecision MedicineMultiomicsMultiomicsGenomics
• AI Meets Multiomics Sequencing: The Technology Ecosystem for Precision Medicine
  This paper examines the convergence of artificial intelligence, multiomics sequencing, digital health technologies, and standards-based governance within the emerging field of precision medicine. It presents the Nebusis® Precision Care System™, a healthcare ec…
  datacite Alvarado Martinez, Celso 2025 置信度 0.66 Precision MedicinePrecision MedicineMultiomicsMultiomicsGenomics
• AI Meets Multiomics Sequencing: The Technology Ecosystem for Precision Medicine
  This paper examines the convergence of artificial intelligence, multiomics sequencing, digital health technologies, and standards-based governance within the emerging field of precision medicine. It presents the Nebusis® Precision Care System™, a healthcare ec…
  datacite Alvarado Martinez, Celso 2025 置信度 0.66 Precision MedicineMultiomicsGenomicsArtificial IntelligenceHealthcare Informatics
• AI Meets Multiomics Sequencing: The Technology Ecosystem for Precision Medicine
  This paper examines the convergence of artificial intelligence, multiomics sequencing, digital health technologies, and standards-based governance within the emerging field of precision medicine. It presents the Nebusis® Precision Care System™, a healthcare ec…
  datacite Alvarado Martinez, Celso 2025 置信度 0.66 Precision MedicineMultiomicsGenomicsArtificial IntelligenceHealthcare Informatics
• Untangling cryptic diversity in New Zealand skinks – a genome-wide analysis of two species complexes
  While anthropogenic activity is driving major declines in global biodiversity, our understanding surrounding the number of species that exist on Earth remains remarkably incomplete, limiting our ability to accurately quantify and manage these losses. New Zeala…
  datacite Davis, Angus Sonny 2026 置信度 0.66 GenomicsEvolutionary biologyBiogeography and phylogeography
• Artificial Intelligence for Genomic Science: A Scoping Review of Concepts, Architectures, Applications, and Open Challenges
  This OSF project supports the scoping review Artificial Intelligence for Genomic Science: Concepts, Architectures, Applications, and Open Challenges. The review maps how AI, spanning traditional machine learning, deep neural networks, graph methods, and large …
  datacite Rodrigues, Wellington, Aristóteles Góes-Neto 2026 置信度 0.66 Physical Sciences and MathematicsMedicine and Health SciencesLife SciencesEducationEngineering
• TumorGene project
  High-throughput, whole-genome sequencing data from human patient samples. The material was generated for research that focuses on human tumor susceptibility as well as somatic cancer genomics. The data is stored in an industry-standard file format (FASTQ). The…
  datacite Aaltonen, Lauri 2026 置信度 0.66 high-throughput sequencingwhole-genome sequencinghuman tumor susceptibilitycancer genomics
• Butterfly taxa discovery via genomic analysis
  Expanding a genomics-guided assessment of butterfly taxonomy, we integrate phylogenetic evidence from all protein-coding genes with morphological considerations to refine our understanding of butterfly systematics and discover new taxa. As a result, 2 subgener…
  datacite Zhang, Jing, Cong, Qian, Shen, Jinhui, Song, Leina 等 2026 置信度 0.66
• Butterfly taxa discovery via genomic analysis
  Expanding a genomics-guided assessment of butterfly taxonomy, we integrate phylogenetic evidence from all protein-coding genes with morphological considerations to refine our understanding of butterfly systematics and discover new taxa. As a result, 2 subgener…
  datacite Zhang, Jing, Cong, Qian, Shen, Jinhui, Song, Leina 等 2026 置信度 0.66
• Sheaf-Theoretic Approach to Multiscale Pathophysiological Mapping: A Topological Framework for Clinical Data Integration and Disease Modeling
  English (opzionale, ma raccomandato per Zenodo): This preprint introduces a methodological proposal for the systematic mapping of the human organism and its pathologies using the mathematical formalism of Sheaf Theory [1, 2]. To address the increasing complexi…
  datacite Usai, Luigi 2026 置信度 0.66 HomeostasisMathematical MedicineNeurosymbolic AITopological Data AnalysisPathophysiological Mapping
• 1st Czech PhD Bioinformatics Conference
  This book of abstracts presents research showcased at the 1st Czech PhD Bioinformatics Conference (Telč, March 27–28, 2025), highlighting current advances in bioinformatics and related interdisciplinary fields across Czech research institutions. The contributi…
  datacite Charles University Bioinformatics 2025 置信度 0.66 BioinformaticsFOS: Computer and information sciencesArtificial intelligenceComputational BiologyBiomedical Data Analysis
• 1st Czech PhD Bioinformatics Conference
  This book of abstracts presents research showcased at the 1st Czech PhD Bioinformatics Conference (Telč, March 27–28, 2025), highlighting current advances in bioinformatics and related interdisciplinary fields across Czech research institutions. The contributi…
  datacite Charles University Bioinformatics 2025 置信度 0.66 BioinformaticsFOS: Computer and information sciencesArtificial intelligenceComputational BiologyBiomedical Data Analysis
• Archaic ancestry inference in imputed ancient human genomes
  Archaic ancestry inference in imputed ancient human genomes Capodiferro M.R.1+*, Planche L.2+*, Breslin E.M.1, Ongaro L.1, Ávila-Arcos M.C.3, Jay F.2, Cassidy L.M.1, Huerta-Sanchez E. 1,4* 1 Smurfit Institute of Genetics, Trinity College Dublin, D02 CX56 Dubli…
  datacite Capodiferro, Marco Rosario, Planche, Léo, Breslin, Emily M., Ongaro, Linda 等 2026 置信度 0.66 Archaic Introgression, Imputation, Ancient DNA, Selection
• Archaic ancestry inference in imputed ancient human genomes
  Archaic ancestry inference in imputed ancient human genomes Capodiferro M.R.1+*, Planche L.2+*, Breslin E.M.1, Ongaro L.1, Ávila-Arcos M.C.3, Jay F.2, Cassidy L.M.1, Huerta-Sanchez E. 1,4* 1 Smurfit Institute of Genetics, Trinity College Dublin, D02 CX56 Dubli…
  datacite Capodiferro, Marco Rosario, Planche, Léo, Breslin, Emily M., Ongaro, Linda 等 2026 置信度 0.66 Archaic Introgression, Imputation, Ancient DNA, Selection
• One State, Five Waves, Ten Dimensions: A Comprehensive Review of SARS-CoV-2 Genomic Surveillance in Goa, India (2020–2025) with a Futuristic Roadmap
  This review synthesises the complete findings of nine original research papers on SARS-CoV-2 genomic surveillance in Goa, India (Kamat et al., 2026a–i), representing the most comprehensive multi-dimensional genomic analysis of SARS-CoV-2 for any Indian state d…
  datacite Kamat, Nandkumar, Albuquerque, Marina, Pinto, Samantha Isabella 2026 置信度 0.66 SARS-CoV-2; review; genomic surveillance; Goa; India; five waves; molecular clock; PANGO lineages; vaccine epitopes; surveillance infrastructure; One Health; futuristic roadmap; GISAID; INSACOG
• One State, Five Waves, Ten Dimensions: A Comprehensive Review of SARS-CoV-2 Genomic Surveillance in Goa, India (2020–2025) with a Futuristic Roadmap
  This review synthesises the complete findings of nine original research papers on SARS-CoV-2 genomic surveillance in Goa, India (Kamat et al., 2026a–i), representing the most comprehensive multi-dimensional genomic analysis of SARS-CoV-2 for any Indian state d…
  datacite Kamat, Nandkumar, Albuquerque, Marina, Pinto, Samantha Isabella 2026 置信度 0.66 SARS-CoV-2; review; genomic surveillance; Goa; India; five waves; molecular clock; PANGO lineages; vaccine epitopes; surveillance infrastructure; One Health; futuristic roadmap; GISAID; INSACOG
• Additional file 1 of Comparative genomics reveal signatures of ecological specialization in the striped ambrosia beetle Trypodendron lineatum
  Additional file 1: Supplementary Table 1. Summary of beetle species included in comparative genomics and orthology analyses. For each species, taxonomic family, GenBank accession number, protein sequence source, and inclusion status in ortholog analysis are in…
  datacite Montes-Ortiz, Zaide, Powell, Daniel, Vogel, Heiko, Löfstedt, Christer 等 2026 置信度 0.66 GeneticsFOS: Biological sciences
• Additional file 1 of Comparative genomics reveal signatures of ecological specialization in the striped ambrosia beetle Trypodendron lineatum
  Additional file 1: Supplementary Table 1. Summary of beetle species included in comparative genomics and orthology analyses. For each species, taxonomic family, GenBank accession number, protein sequence source, and inclusion status in ortholog analysis are in…
  datacite Montes-Ortiz, Zaide, Powell, Daniel, Vogel, Heiko, Löfstedt, Christer 等 2026 置信度 0.66 GeneticsFOS: Biological sciences
• BETTER-B: Transcriptomic data (fastq files & count files) of the hemocytes of Apis mellifera (from 1-day old nurse bees and L5-larvae)
  In March 2024, honey bees (A. mellifera carnica) were collected by removing closed brood frames with ready-to-emerge honey bees from the UGENT apiary (51°1’29”N, 3°42’42”E). These frames were incubated in a temperature chamber at 34°C until emergence. Honey be…
  datacite Braeckman, Merel, De Smet, Lina, de Graaf, Dirk 2025 置信度 0.66 HemocytesTranscriptome
• BETTER-B: Transcriptomic data (fastq files & count files) of the hemocytes of Apis mellifera (from 1-day old nurse bees and L5-larvae)
  In March 2024, honey bees (A. mellifera carnica) were collected by removing closed brood frames with ready-to-emerge honey bees from the UGENT apiary (51°1’29”N, 3°42’42”E). These frames were incubated in a temperature chamber at 34°C until emergence. Honey be…
  datacite Braeckman, Merel, De Smet, Lina, de Graaf, Dirk 2025 置信度 0.66 HemocytesTranscriptome
• Multi-omics approaches to understand depression associated Alzheimer's disease
  Depression and Alzheimer’s disease (AD) are commonly comorbid in the elderly, and an increasing body of evidence indicates that depression in late-life could be a prodromal manifestation and a risk factor on its own in AD. There is some similarity in the patho…
  datacite Mediterranean Journal of Medicine and Medical Sciences 2026 置信度 0.66 Pharmacology
• Multi-omics approaches to understand depression associated Alzheimer's disease
  Depression and Alzheimer’s disease (AD) are commonly comorbid in the elderly, and an increasing body of evidence indicates that depression in late-life could be a prodromal manifestation and a risk factor on its own in AD. There is some similarity in the patho…
  datacite Mediterranean Journal of Medicine and Medical Sciences 2026 置信度 0.66 Pharmacology
• India's Food Culture: 6 Ancient Nutritional Principles That Became Modern Science
  This article examines six ancient Indian nutritional principles as documented in the Charaka Samhita, Taittiriya Upanishad, Bhagavad Gita, and Ashtanga Hridaya, and evaluates the modern scientific evidence confirming each principle's validity. The six principl…
  datacite Rout, Narayan 2026 置信度 0.66 India ancient food culture nutritional principlesRitu Bhoga Hita Bhoga Mita Bhoga AyurvedaAnnam Brahma Taittiriya Upanishad food philosophyAhara Vidhi Charaka Samhita eight principles eatingAgni digestive fire gut microbiome modern science
• India's Food Culture: 6 Ancient Nutritional Principles That Became Modern Science
  This article examines six ancient Indian nutritional principles as documented in the Charaka Samhita, Taittiriya Upanishad, Bhagavad Gita, and Ashtanga Hridaya, and evaluates the modern scientific evidence confirming each principle's validity. The six principl…
  datacite Rout, Narayan 2026 置信度 0.66 India ancient food culture nutritional principlesRitu Bhoga Hita Bhoga Mita Bhoga AyurvedaAnnam Brahma Taittiriya Upanishad food philosophyAhara Vidhi Charaka Samhita eight principles eatingAgni digestive fire gut microbiome modern science
• Single-cell amplified genomes (SAGs) collected during CTD casts in the Eastern Tropical Pacific Ocean on R/V Atlantis cruise AT50-08 during February-March 2023
  This dataset describes assembled genomes of single-cell amplified genomes (SAGs) used in Zhao et al., ISME 2025. Water samples were collected during conductivity–temperature–depth (CTD) casts from an oxygen minimum zone in the Eastern Tropical Pacific Ocean, w…
  datacite Kostas Konstantinidis 2026 置信度 0.66
• Genotypic and phenotypic features of 23 Egyptian patients with tuberous sclerosis complex
  Abstract Background Tuberous sclerosis complex (TSC) is a multisystem disease caused by pathogenic variants in TSC1 or TSC2 genes. Although features of TSC have been described in various populations, genetic data from Egypt remain scarce. This study aimed to c…
  datacite Othman, Amr A., Sadek, Abdelrahim A., Aladawy, Mohammed A., Aziz, Shereen Philip 等 2026 置信度 0.66 GeneticsFOS: Biological sciences
• Genotypic and phenotypic features of 23 Egyptian patients with tuberous sclerosis complex
  Abstract Background Tuberous sclerosis complex (TSC) is a multisystem disease caused by pathogenic variants in TSC1 or TSC2 genes. Although features of TSC have been described in various populations, genetic data from Egypt remain scarce. This study aimed to c…
  datacite Othman, Amr A., Sadek, Abdelrahim A., Aladawy, Mohammed A., Aziz, Shereen Philip 等 2026 置信度 0.66 GeneticsFOS: Biological sciences
• Fungal Primacy, Host HOCl Collapse, and the Redox Bridge: A Systematic Evidence Synthesis Integrating Mycobiome Dysbiosis, Hierarchical Infection, and the Translational Reinterpretation of Exogenous ClO₂
  The human mycobiome has been systematically excluded from microbiome research by >99% of studies using 16S rRNA (bacterial‑only) sequencing. We propose the Fungal Primacy Hypothesis (FPH): chronic low‑grade fungal dysbiosis (Candida, Aspergillus, Kazachstania)…
  datacite Fortes, B. A. C. 2026 置信度 0.66 Mycobiome dysbiosis, Fungal Primacy Hypothesis, HOCl, chlorine dioxide ClO2, Th2/Treg, MPO-halide system, RcrB, redox reboot, systematic evidence synthesis
• Fungal Primacy, Host HOCl Collapse, and the Redox Bridge: A Systematic Evidence Synthesis Integrating Mycobiome Dysbiosis, Hierarchical Infection, and the Translational Reinterpretation of Exogenous ClO₂
  The human mycobiome has been systematically excluded from microbiome research by >99% of studies using 16S rRNA (bacterial‑only) sequencing. We propose the Fungal Primacy Hypothesis (FPH): chronic low‑grade fungal dysbiosis (Candida, Aspergillus, Kazachstania)…
  datacite Fortes, B. A. C. 2026 置信度 0.66 Mycobiome dysbiosis, Fungal Primacy Hypothesis, HOCl, chlorine dioxide ClO2, Th2/Treg, MPO-halide system, RcrB, redox reboot, systematic evidence synthesis
• Data and code from: Using landscape genomics to define species distributions, delineate seed zones, and predict genomic offset to future climate for the interior spruce hybrid complex (<em>Picea glauca, Picea engelmannii</em>, and their hybrids
  Understanding how tree species adapt to climate is crucial for forest management under climate change. This study employs landscape genomics to investigate climate adaptation in the interior spruce complex (Picea glauca, P. engelmannii, and their hybrids) acro…
  datacite Ye, Zhengyang, Aitken, Sally, Rieseberg, Loren, Wang, Tongli 2026 置信度 0.66 FOS: Agriculture, forestry, and fisheriesFOS: Earth and related environmental sciencesFOS: Earth and related environmental sciencesFOS: Environmental biotechnologyFOS: Environmental biotechnology
• Single-center Experience with Comprehensive Genomic Profiling Using Circulating Tumor DNA for Metastatic Colorectal Cancer.
  Comprehensive genomic profiling (CGP) using circulating tumor DNA (ctDNA) has recently become available in Japan, but its clinical utility in daily practice remains unclear. We retrospectively evaluated 19 patients with metastatic colorectal cancer (mCRC) who …
  pubmed Ito K, Kataoka K, Muroi Y, Koba M 等 2026 置信度 0.82
• Diagnostic value of metagenomic next-generation sequencing in deep neck space infections: a retrospective study of 32 patients.
  Deep neck space infections (DNSI) are rapidly progressive suppurative conditions in which early identification of causative pathogens is critical for clinical decision-making. This study evaluated the diagnostic performance and clinical utility of metagenomic …
  pubmed Wang Z, Yang H, Liu J, Li X 2026 置信度 0.82
• Evolution of fruit functional traits provides insights into the drivers of cycle-cup oaks (Quercus section Cyclobalanopsis) diversification in evergreen broadleaf forests.
  The impact of key traits on lineage diversity remains a central focus in macroevolutionary research. Seeds, encapsulated within fruits, carry the complete genetic blueprint of their species, and the capacity of their adaptive evolution to diverse environmental…
  pubmed Yang LH, Jaganathan GK, Liang SD, Zheng SS 等 2026 Jul 置信度 0.82
• Practices and perceptions of antibiotic use in canine breeding: a survey among breeders and veterinarians.
  Antibiotic use in canine breeding, particularly prior to mating, is frequently discussed in practice despite increasing awareness of antimicrobial stewardship and the recognition that the canine vaginal tract naturally harbors a microbiome. Diagnostic uncertai…
  pubmed Spanoghe L, Quaaden A, Lannoo J, Banchi P 等 2026 置信度 0.82
• Graph in Graph (GiG): A novel graph AI framework for integrating and interpreting medical and omics data.
  Medical records and omics data are rapidly becoming standard in healthcare settings, which characterize the whole-person from dysfunctional molecules to phenotypes, and thus offer potential for precise disease diagnosis and target discovery. Whereas, it remain…
  pubmed Zhang H, Lu Y, Fang K, Xu Z 等 2026 Jul 24 置信度 0.82
• Village-level surveillance of neonatal disease with integrated real-time dashboards and quality-control in Uganda.
  Neonatal mortality remains disproportionately high in sub-Saharan Africa, where an estimated 27 neonatal deaths per 1,000 live births occur annually. Infections, including sepsis and meningitis, account for a substantial proportion of these deaths, while neura…
  pubmed Paulson JN, Whalen AJ, Tindimwebwa S, Hansen J 等 2026 Jul 23 置信度 0.82
• Circulating Mitochondrial DNA Measures Across Malignancies: Diagnostic Accuracy and Prognostic Associations.
  Circulating mitochondrial DNA is being investigated as a liquid-biopsy biomarker because of its high copy number and release during cellular stress. However, diagnostic estimates vary across tumor types and assays, and prognostic studies have measured both cel…
  pubmed Zhang Z, Jiang Y, Gong Y, Xie H 等 2026 Aug 置信度 0.82
• Transposable elements in the era of data science EMBO course: a call for open, accessible, and collaborative TE resources.
  This community letter represents a collective outcome from the EMBO Practical Course "Transposable Elements in the Era of Data Science" held at the Rosalind Franklin Institute from 12 to 16 May 2025, Didcot, United Kingdom ( https://meetings.embo.org/event/25-…
  pubmed Paschoal AR, de Goes FR, Makałowski W, Karakülah G 等 2026 Jul 31 置信度 0.82
• From potential to practice: a UK national roadmap to implement pathogen whole-genome sequencing in infection prevention and control.
  Whole-genome sequencing has substantially advanced the understanding of infection transmission but remains underused in everyday infection prevention and control. The UK pioneered genomic medicine through the 100&#x2009;000 Genomes Project, tuberculosis survei…
  pubmed Price JR, Otter JA, Snell LB, Eyre DW 等 2026 Jul 31 置信度 0.82
• Genomic insights into flooding tolerance of Distylium chinense in the water-level fluctuation zone of the Three Gorges Reservoir.
  The intensification of climate change has led to frequent extreme flooding events, which threaten plant growth and food security. Studying the molecular mechanisms underlying plant flooding resistance is crucial for germplasm improvement. Distylium chinense, a…
  pubmed Xia C, Ding B, Zhang X, Zhang X 等 2026 Aug 置信度 0.82
• Genetically predicted cognitive performance and risk of meniscal derangement: A 2-sample Mendelian randomization study.
  The causal relationship between cognitive performance and meniscal derangement is unclear. This study aims to investigate the potential genetic association between cognitive performance and meniscal derangement. We conducted a 2-sample Mendelian randomization …
  pubmed Li C, Zhang M, Yin J, Cao D 等 2026 Jul 31 置信度 0.82
• Loss of lncRNA AK015322 increases sperm morphological abnormalities and impairs motility in mice.
  Infertility has long been a major health concern worldwide, with male infertility accounting for approximately half of all cases. In recent years, increasing evidence has shown that long non-coding RNAs (lncRNAs) are involved in the regulation of spermatogenes…
  pubmed Zhu Q, Pan S, Li X, An C 等 2026 Jul 31 置信度 0.82
• UCHL1-mediated deubiquitination of PARK7 suppresses ferroptosis and enhances tumor progression in triple-negative breast cancer.
  Triple-negative breast cancer (TNBC) has a poor prognosis due to the lack of targeted treatment. Previous studies have shown that the deubiquitinase UCHL1 is significantly upregulated in TNBC tissues and positively correlated with shorter overall survival in p…
  pubmed Chen S, Liang N, Zhang Y, Li Z 等 2026 Jul 31 置信度 0.82
• Acute and Chronic Leukemia in Sub-Saharan Africa: A Systematic Review.
  The four primary subgroups of leukemia include chronic myeloid leukemia (CML), acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), and chronic lymphocytic leukemia (CLL). Very little is known about the regional variation of leukemia and subtypes …
  pubmed Ayirebi AA, Twumasi S, Olaga LK, Sackey B 等 2026 Aug 置信度 0.82
• Hemp Flower Oil and Occupational Pain Management in Farming Communities: A Systematic Review.
  Musculoskeletal pain is a major concern for agricultural workers worldwide. However, access to safe and non-opioid pain relief measures is limited in resource-scarce settings. Hemp flower oil, a rich source of cannabinoids and terpenes, has been recognised as …
  pubmed Kaye T, Komane B 2026 置信度 0.82
• Pacificoceanicola niger sp. nov. and Pacificoceanicola algae sp. nov., isolated from the brown alga Saccharina japonica, with the reclassification of Tropicibacter oceani as Pacificoceanicola oceani comb. nov.
  Two Gram-stain-negative, non-motile and oval-shaped bacterial strains, designated 2E107 T and 2E233 T , were isolated from the brown alga Saccharina japonica collected in Rongcheng, Weihai, China (122&#xb0; 33' E 37&#xb0; 15' N). The two strains shared 98.0% 1…
  pubmed Wang L, Sun C, Wang S, Liu T 等 2026 Jul 置信度 0.82
• Advanced Imaging and Biomarker Discovery for Early Diagnosis in Skull Base Pathology.
  Early detection of skull base (SB) tumors and inflammatory lesions remains difficult because of deep location, complex anatomy, and subtle clinical prodromes. This study systematically evaluates contemporary advanced imaging techniques and emerging molecular b…
  pubmed Gupta K, Gupta S 2026 Sep 置信度 0.82
• Genetic Polymorphisms Associated with Obesity in Southeast Asian Populations: A Systematic Review without Meta-Analysis.
  Obesity is a growing global public health challenge, with genetic factors playing a crucial role in its development. This review synthesises findings from Southeast Asian studies to investigate the association between gene polymorphisms and obesity risk across…
  pubmed Vijakumaran U, Abdul Murad NA, Abdul Jalal MI, Fong CS 等 2025 Dec 置信度 0.82
• Modeling production curves in a strawberry breeding program to optimize early season productivity.
  Florida and California produce 98% of U.S. strawberries, with Florida growers' profitability depending on high yields early in the season (November-January), when prices are the highest in the U.S. market. This study aims to model the cumulative Marketable Yie…
  pubmed Kaur S, Sleper J, Dalid C, Garcia-Abadillo J 等 2026 置信度 0.82
• Farm-to-fork microbial safety of fresh leafy green vegetables: Navigating the gap between experimental interventions and industrial scale-up.
  The increasing global consumption of minimally processed leafy greens has frequently positioned them as vehicles for foodborne pathogens, imposing a heavy economic burden on healthcare systems. Although farm-to-fork transmission pathways have been documented e…
  pubmed Ndraha N, Aditya S, Damayanti E, Frediansyah A 等 2026 Jul 30 置信度 0.82
• Development and Usability Testing of an Information Needs-Based Chatbot for Individuals With Pathogenic Variants in BRCA Genes in Korea: A Methodological Study.
  Korean individuals with BRCA pathogenic/likely pathogenic (P/LP) variants have limited access to genetic counseling due to shortages of genetic professionals and lack of reimbursement. Despite the growing interest in digital health interventions, few digital c…
  pubmed Park SY, Kim Y, Katapodi MC, Kim S 2026 Aug 置信度 0.82
• Limited, outbreak-biased and unevenly reported: genomic insights into vancomycin-resistant Enterococcus faecium in Germany as reported between 2015 and 2025.
  Whole-genome sequencing (WGS) has improved our understanding on epidemiology and transmission of vancomycin-resistant Enterococcus faecium (VRE). However, regional differences in strain distribution patterns remain poorly reported. In this narrative review, we…
  pubmed Rath A, Schneider-Brachert W 2026 Jul 30 置信度 0.82
• Single-cell spatial mapping of human kidney development implicates the microenvironment in guiding cell fate decisions.
  Evolution has used cell-cell communication as a strategy to coordinate organ development, enabling the reproducible generation of intricate structures. Classically, these interactions have been studied one at a time in model organisms, limiting our understandi…
  pubmed Levinsohn J, Grindel S, Dumoulin B, Abedini A 等 2026 Aug 置信度 0.82
• Cross-species variant-to-function analyses implicate MEIS1 in conferring sleep abnormalities and impaired cerebellar development.
  Genome-wide association studies (GWAS) have identified numerous loci for insomnia, yet functional validation of effector genes remains limited because most risk variants lie in noncoding regions, and the true causal gene is not known. Here, we use prior human …
  pubmed Zimmerman AJ, Almeraya Del Valle E, Pahl MC, Doldur-Balli F 等 2026 Aug 13 置信度 0.82
• Resolving the subcellular redox landscape of Coenzyme Q.
  Coenzyme Q (CoQ) is an essential electron carrier and lipophilic antioxidant whose biological functions depend on its redox state. However, accurate measurement of reduced and oxidized CoQ is hindered by rapid ex vivo oxidation during sample preparation and an…
  pubmed Kim TH, Nguyen CTN, Jang D, Lee SB 等 2026 Jul 30 置信度 0.82
• Real-World Feasibility Assessment of Short-Course Preoperative Endocrine Therapy Using the Ki67 Biomarker in an Australian Cohort of Patients With Estrogen Receptor-Positive Early Breast Cancer.
  Preoperative endocrine therapy (ET) can be used in the lead-up to surgery in estrogen receptor positive (ER+) early breast cancer (eBC), without delaying surgery. Preoperative ET (pET) may not yield clinically significant tumor shrinkage, unlike conventional n…
  pubmed Nilsen OJ, Williams DS, Tsao CS, White S 等 2026 Aug 置信度 0.82
• Beyond the scales: Marine archaeogenomics for the conservation and restoration of fisheries.
  Protection and restoration of marine environments are essential for food security and climate change mitigation. Yet historical and archaeological research have shown that conservation and management often rely on arbitrary ecological baselines in ecosystems a…
  pubmed Atmore LM, Star B 2026 Jul 30 置信度 0.82
• CRP-dependent DNA anchoring and membrane sequestration define a dual mechanism for MtlR-mediated regulation.
  Mannitol is a widely distributed sugar alcohol and a primary carbon source for diverse microbial communities, serving as a substrate for producing high-value metabolites. In Gammaproteobacteria, the conserved mtl operon is essential for mannitol metabolism, en…
  pubmed Lee SH, Kim Y, Kim G, Choe M 等 2026 Jul 17 置信度 0.82
• XXYLT1 and Mendelian Retinal Dystrophy.
  Substantial unexplained heritability remains for pathogenic inherited retinal disease (IRD) variants. Application of genome-wide association studies (GWAS) could help identify causal genes in rare diseases.
  pubmed Kraatari-Tiri M, Ishtiaq H, Tyrmi J, Lin S 等 2026 Jul 30 置信度 0.82
• Breast and Ovarian Cancer Among Individuals Undergoing BRCA1 and BRCA2 Testing.
  Pathogenic variants in BRCA1 and BRCA2 confer substantial risks of breast and ovarian cancer; however, risk for female individuals undergoing testing, particularly those with variants of uncertain significance (VUS) or negative results, remain poorly defined.
  pubmed Dossa F, Metcalfe K, Ante Z, Liu N 等 2026 Jul 1 置信度 0.82
• Emerging biomarkers in breast fibroadenoma: implications for differential diagnosis, malignant transformation, and precision medicine.
  Fibroadenoma is the most common benign fibroepithelial lesion of the breast; it occurs most frequently in adolescents and women of reproductive age. While fibroadenoma is considered a non-invasive lesion with a good prognosis, some fibroadenomas may show rapid…
  pubmed Ravi N, Sankar R, Mathavan A, Rayala SK 等 2026 Jul 30 置信度 0.82
• Automated Deauville Score computation from baseline [¹⁸F]FDG PET/CT predicts progression-free survival in multiple myeloma: a radiogenomic framework.
  Deauville Score (DS) assessment from [ 18 F]FDG PET/CT in multiple myeloma (MM) relies on visual interpretation, limiting reproducibility. This study aimed to develop an automated pipeline for standardised DS computation, evaluate the prognostic value of DS at…
  pubmed Peluso S, Polizzi S, Pagnini L, Tarozzi M 等 2026 Jul 30 置信度 0.82
• Cell-cell communication in bacteria: new insights and future trends.
  pubmed Venturi V, Leoni L 2026 Jul 置信度 0.82
• Machine learning-driven evaluation of protein kinase D3 as a co-diagnostic biomarker in hepatocellular carcinoma.
  To elucidate the diagnostic value and clinical relevance of protein kinase D3 (PRKD3) in hepatocellular carcinoma (HCC), we analyzed data retrieved from The Cancer Genome Atlas (TCGA) database, which revealed high expression of PRKD3 in HCC tissues. Subsequent…
  pubmed Li J, Zhao Y, Ma Y, Xie B 等 2026 Jun 20 置信度 0.82
• The evolving landscape of African swine fever: the game-changing impact of recombinant genotype I/II on Asia-Pacific control strategies.
  The emergence of genotype I/II recombinant African swine fever virus (rASFV) in the Asia-Pacific region represents a significant shift in the molecular epidemiology of the ongoing ASF panzootic. Following the PRISMA-ScR framework, this study synthesizes source…
  pubmed Hsu JC, Schambow RA, Huang YL, Chuong VD 等 2026 置信度 0.82
• Enhancing genomic prediction of wheat resistance to fusarium head blight through integration of passive resistance traits.
  Fusarium head blight (FHB) is one of the most devastating wheat diseases worldwide. Wheat resistance to FHB is controlled by multiple small-effect genes involved in active and passive resistance mechanisms. Complex resistance can be successfully managed using …
  pubmed Gorash A, Syed S, Brazauskas G 2026 置信度 0.82
• The Application and Advancement of Herbal Medicine in Gastrointestinal Cancers: A Bibliometrix Visualization and Pan-cancer Analysis.
  Herbal medicine has emerged as an important area of investigation in gastrointestinal cancers owing to its multitarget therapeutic potential and growing integration with modern oncology. However, the rapid expansion of the literature has resulted in a fragment…
  pubmed Zhao L, Wang H, Jiang Y, Zhao Z 等 2026 Jul 30 置信度 0.82
• VAF-tumor content graph: a simple visual framework for interpreting hereditary cancer variants and supporting genetic counseling in tumor-only sequencing.
  Comprehensive genomic profiling (CGP) using tumor-only sequencing detects pathogenic or likely pathogenic (P/LP) variants in hereditary cancer susceptibility genes (HCSGs). However, interpreting the biological origin and clinical significance of detected varia…
  pubmed Kashima M, Tsubamoto H, Ueda T, Kinjo C 等 2026 Jul 29 置信度 0.82
• Translating genomic data into healthcare practice with the Singapore National Precision Medicine program.
  The Singapore National Precision Medicine (NPM) program is a three-phase whole-of-nation effort designed to develop scalable, evidence-based solutions for precision health tailored to Asia's diverse populations. Here we present NPM phase II (2020-2025), highli…
  pubmed Seow SW, Mina T, Hebrard M, Sadhu N 等 2026 Aug 置信度 0.82
• Enabling data-driven decision-making for innovative health care and delivery in Africa.
  The information age, fueled by globalization and technological advancements, has transformed the data landscape, impacting decision-making, management, governance, and policy intervention across various sectors. The health sectors are no exception, experiencin…
  pubmed Agamah FE, Anyanful A, Ryabinina O, Twum J 等 2025 Dec 16 置信度 0.82
• MuTATE: an interpretable multi-endpoint machine learning framework for automated molecular subtyping in cancer.
  Effective and interpretable molecular subtyping is critical for cancer risk stratification and treatment, yet existing methods face key limitations. Traditional models cannot jointly model multiple clinical endpoints, limiting prognostic utility, while machine…
  pubmed Ayton SG, Pavlicova M, Robles-Espinoza CD, Fuentes-Aguilar RQ 等 2025 Jul 3 置信度 0.82
• Retrospective evaluation of caregiver-administered buccal midazolam for pediatric status epilepticus in a regional core hospital in Japan.
  Status epilepticus (SE) is a frequent pediatric neurological emergency in which rapid seizure control is needed to prevent neurological injury. Buccal midazolam (Buc-MDL) is a noninvasive first-line benzodiazepine for prehospital pediatric SE; nonetheless, rea…
  pubmed Akiba T, Shimada S, Matsuda S, Hamahara A 等 2026 Jul 23 置信度 0.82
• Comparative in silico analysis of Apis mellifera immune responses to Varroa destructor and Tropilaelaps mercedesae: Common and mite-specific molecular signatures.
  Parasitic mites Varroa destructor and Tropilaelaps mercedesae represent major threats to global honey bee (Apis mellifera) health and productivity, yet comparative molecular insights into host responses remain limited. To address this, we systematically compil…
  pubmed Kiani R, Davoodi P 2026 Jul 24 置信度 0.82
• Epilepsy with fever-sensitivity in patients with ATP6V0C pathogenic variants.
  Fever can trigger seizures in several early-onset epilepsies. SCN1A-related epilepsies, including Dravet Syndrome, are the best characterised conditions in this spectrum, but a growing number of genes implicated in fever-sensitive epilepsies have emerged. We a…
  pubmed Tanganelli FMA, Di Feo MF, Madia F, Chiarella L 等 2026 Sep 置信度 0.82
• A comprehensive map of missense trafficking variants in rhodopsin and their response to pharmacologic correction.
  Rhodopsin ( RHO ) missense variants are a leading cause of autosomal dominant retinitis pigmentosa (adRP), a progressive retinal degeneration. Interpreting RHO variant pathogenicity is challenging, and understanding their disease mechanisms is essential for de…
  pubmed Manian KV, Ludwig CH, Zhao Y, Abell NS 等 2026 Jul 31 置信度 0.82
• Genomic Testing Uptake Among Medicare Beneficiaries With Cancer.
  Genomic testing plays a central role in precision oncology by guiding targeted therapies. Medicare established national coverage determinations (NCDs) for next-generation sequencing (NGS) in 2018 and 2020, yet population-level adoption patterns remain underexa…
  pubmed Kang SY, Zhang R, Kim C, Schwartz MD 等 2026 Jul 1 置信度 0.82
• Global Burden of Elevated LDL-C: Findings From the Global Burden of Disease Study 2023.
  Elevated low-density lipoprotein cholesterol (LDL-C) is a modifiable risk factor for cardiovascular disease, the leading cause of premature death worldwide. Assessing the LDL-C-related burden is critical for guiding prevention and treatment strategies.
  pubmed GBD 2023 LDL Cholesterol Collaborators, Razo C, DeCleene NK, Johnson CO 等 2026 Aug 25 置信度 0.82
• abCRISPR: deep learning-based design of abasic gRNA sequences for specific CRISPR-Cas9 genome editing.
  CRISPR-Cas9 has become a widely used tool for genome editing. However, its off-target cleavage caused by partial sequence matches with guide RNAs (gRNAs) remains a critical limitation. Recently, abasic gRNAs (&#xd8;X&#xd8;) have been developed to enhance targe…
  pubmed Kim GD, Gu D, Park M, Chi SW 2026 置信度 0.82
• Retinal proteome changes mirror brain pathology and reveal synaptic and cytoskeletal dysfunction in Alzheimer's disease.
  Visual dysfunction is increasingly recognized as an important feature of Alzheimer's disease, and substantial retinal changes have been documented across multiple studies. Yet the molecular changes underlying retinal neurodegeneration and which retinal protein…
  pubmed Santiago J, Pocevičiūtė D, Sällberg T, Önnerfjord P 等 2026 Jul 29 置信度 0.82
• Progerin Hinders Autophagy Flux at Its Final Stages in Hutchinson-Gilford Progeria Syndrome Cells, Preventing Its Own Autophagic Degradation.
  In Hutchinson-Gilford progeria syndrome (HGPS), dysfunctional autophagy results in the accumulation of progerin, a lamin A mutant variant that alters a plethora of processes, inducing senescence and driving premature aging. Therefore, the elimination of proger…
  pubmed García-Aguirre I, Reyes-Martínez JA, Unzueta J, Guevara-Namorado F 等 2026 Aug 置信度 0.82
• Single-cell profiling reveals immunometabolic remodeling with T-cell dysfunction in HIV-1 infected people.
  Immunometabolism plays a vital role in the immunopathogenesis of people living with human immunodeficiency virus type 1 (HIV-1) (PLWH). However, the precise relationship between metabolic profiles and T-cell dysfunction in this population remains unclear. This…
  pubmed Zhao JF, Zhen C, Wang YY, Zhou MJ 等 2026 Apr 置信度 0.82
• Unraveling chikungunya's viral tapestry through molecular mechanisms and clinical insights.
  Chikungunya fever (CHIKF) is an arthropod-borne viral disease caused by the chikungunya virus (CHIKV). Patients typically present with fever and symmetric distal polyarthralgia, which may progress to chronic joint sequelae. This review was conducted to systema…
  pubmed Xu H, Gao X, Huang S, Wang H 等 2026 Jan 置信度 0.82
• Emerging zoonotic threats: HKU5-CoV-2 and the CBRNE approach to pandemic prevention.
  The emergence of HKU5-CoV-2, a novel lineage in the Merbecovirus subgenus, represents a potential zoonotic threat with significant implications for global health. This bat-derived virus, which is phylogenetically similar to the Middle East respiratory syndrome…
  pubmed Ludovici GM, Tassi PA, Iannotti A, Russo C 等 2026 Jan 置信度 0.82
• Functional cure for chronic hepatitis B: A state of immune control over cccDNA persistence.
  Functional (clinical) cure is considered a desirable therapeutic endpoint of antiviral therapy for chronic hepatitis B (CHB). Recent studies have detected transcriptionally active covalently closed circular DNA (cccDNA) and integrated hepatitis B virus (HBV) D…
  pubmed Zhao K, Wu L, Wu Y, Jiang Q 等 2026 Apr 置信度 0.82
• Transcript Identification Using Arrayed Hydrogels with TrapFISH.
  3' single-cell transcriptomics aims to uncover transcript abundance across numerous cells to deepen our understanding of cellular diversity. However, sequencing capacity is often a bottleneck in these experiments, limiting the number of cells that can be profi…
  pubmed Morse DB, Toprakcioglu Z, Denduluri-Marthi A, Brenton JD 等 2025 Sep 17 置信度 0.82
• Literature horizon scan for new scientific data on plants, microorganisms and animals, and their products obtained by new genomic techniques (March 2026).
  The European Food Safety Authority has issued several scientific opinions on plants, microorganisms and animals obtained through certain new genomic techniques (NGTs), following requests received by the European Commission. These scientific opinions provided c…
  pubmed European Food Safety Authority (EFSA), Ardizzone M, Barizzone F, Bonatti M 等 2026 Jul 置信度 0.82