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Shikha Thakur, Rajender Kumar, Lokesh Thakur, Sanjeev Thakur
2025-10-14T01:52:48Z
置信度 0.70
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2026-03-31T17:37:04Z
置信度 0.70
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Anna Docherty, Melek Chaouch, Na Cai
2025-10-04T00:56:24Z
置信度 0.70
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Hui-Ling Guo, Meng-Zhi Tian, Xian Ri, Yi-Fang Chen
2024-10-09T19:45:04Z
置信度 0.70
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Runyang Zhou, Xi Peng, Yao Teng, Sian Liu 等
2025-01-22T08:07:49Z
置信度 0.70
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Caiping Chen, Li Xue, Chao Han, Wanxin Wu 等
2025-02-23T15:11:44Z
置信度 0.70
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This chapter introduces the Basic Local Alignment Search Tool (BLAST), a heuristic program developed to perform rapid local sequence alignments in large databases. It outlines the four phases of BLAST—word generation, database scanning, hit extension, and alig…
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Jamil Momand, Eliot Bush
2026-03-27T12:57:12Z
置信度 0.70
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Xiaoli Li, Ding Cui, Yang Liu
2025-09-16T21:55:08Z
置信度 0.70
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Abstract Background Linked-reads improve de novo assembly, haplotype phasing, structural variant (SV) detection, and other applications through highly-multiplexed genome partitioning and barcoding. Whole genome assembly and assembly-based variant detection bas…
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Can Luo, Brock A. Peters, Xin Maizie Zhou
2025-03-18T05:22:44Z
置信度 0.70
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2025-05-21T09:17:16Z
置信度 0.70
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Amir Hasan Taghiloofar, Gülsüm Boztaş, Emine Bayram
2025-11-02T07:31:53Z
置信度 0.70
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Abstract Recent developments in PacBio high-fidelity (HiFi) sequencing technologies have transformed genomic research, with circular consensus sequencing now achieving 99.9% accuracy for long (up to 25 kb) single-molecule reads. This method circumvents biases …
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Bo Wang, Peng Jia, Shenghan Gao, Huanhuan Zhao 等
2025-02-07T12:34:05Z
置信度 0.70
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Abstract The George W. Beadle Award honors individuals who have made outstanding contributions to the community of genetics researchers as a whole and led an exemplary research career. The 2025 awardee is Sudhir Kumar from Temple University, who has not only p…
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Sudhir Kumar
2025-05-20T07:36:08Z
置信度 0.70
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This study obtained four immunological subtypes exhibiting substantial difference in the tumor microenvironment (TME), immune-related pathways, tumor mutational burden, drug sensitivity, and intratumor microbiome. Furthermore, we developed a novel prognostic m…
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Yi Zhou, Lixun Chai, Yuyao Wang, Hongguang Zhang
2025-06-25T11:41:51Z
置信度 0.70
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Ander Díaz-Navarro, Xindi Zhang, Wei Jiao, Bo Wang 等
2025-08-12T14:56:39Z
置信度 0.70
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Naseer Mohammad, Ankur Dahayat, Anuj Maran, Yogeshwar Mishra 等
2025-04-30T04:36:51Z
置信度 0.70
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2025-04-29T17:51:38Z
置信度 0.70
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Yikai Wang, Weibing Shuang
2025-03-10T12:37:44Z
置信度 0.70
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2026-01-07T05:58:26Z
置信度 0.70
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2026-01-07T05:58:26Z
置信度 0.70
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Ugur Temel, Onur Derdiyok
2025-07-01T14:47:55Z
置信度 0.70
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2025-09-21T17:44:39Z
置信度 0.70
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Aswetha Iyer, S. Murugan
2025-03-06T17:01:04Z
置信度 0.70
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2025-05-21T13:17:13Z
置信度 0.70
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2025-09-21T17:44:39Z
置信度 0.70
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2026-01-07T05:58:26Z
置信度 0.70
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2026-01-07T05:58:26Z
置信度 0.70
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2026-01-07T05:58:26Z
置信度 0.70
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2026-01-07T05:58:26Z
置信度 0.70
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This study investigates the promoter region and regulatory elements of chicken insulin‐like growth factor (IGF) and vasoactive intestinal polypeptide (VIP) genes associated with reproductive traits. Several in silico tools, such as Neural Network Promoter Pred…
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Bosenu Abera, Hunduma Dinka, Hailu Dadi, Habtamu Abera
2025-05-26T11:35:59Z
置信度 0.70
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Louise Lyons
2025-01-23T19:17:21Z
置信度 0.70
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Prasann Kumar, Padmanabh Dwivedi
2025-01-31T19:21:24Z
置信度 0.70
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Dan Zhang, Chao Yuan, Xuejiao An, Tingting Guo 等
2024-12-03T00:50:09Z
置信度 0.70
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crossref
2024-11-01T11:38:01Z
置信度 0.70
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Skin, as the body’s primary environmental interface, is continuously exposed to various environmental stressors that significantly impact its genomic integrity and accelerate aging processes. This mini review summarizes current knowledge of the molecular mecha…
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Tran Thuy Duong, Do Tien Son
2025-09-16T08:52:10Z
置信度 0.70
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Wenxin Li, Xinyu Zhang, Jiamin Song, Ling Yang 等
2025-01-05T01:59:37Z
置信度 0.70
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Abstract Forensic DNA analysis plays a pivotal role in personal identification, kinship assessment, and criminal investigations, with Short Tandem Repeat (STR) typing via capillary electrophoresis (CE) long established as the gold standard. However, CE-based S…
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Sharlize Pedroza Matute, Sasitaran Iyavoo
2025-05-28T06:00:51Z
置信度 0.70
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2026-02-04T15:59:31Z
置信度 0.70
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Rajesh Pamanji, Ragothaman Prathiviraj, Yashwanth Bomma, Ashok Sundar Venkateswaran 等
2025-05-27T19:39:40Z
置信度 0.70
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2025-08-04T15:38:23Z
置信度 0.70
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Pooja Garg, Dalveer Singh, Priya Upadhyay, Anamika Kashyap 等
2025-12-08T09:14:24Z
置信度 0.70
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Suddha Chatterjee
2025-02-28T15:32:34Z
置信度 0.70
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Prasann Kumar, Padmanabh Dwivedi
2025-01-31T19:22:02Z
置信度 0.70
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2026-01-07T05:58:26Z
置信度 0.70
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crossref
2025-05-21T13:17:16Z
置信度 0.70
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Abstract Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a well-conserved enzyme across Archaea, Bacteria, and Eukarya, known not only for its canonical role in glycolysis, but also for diverse moonlighting functions including transcription regulation, hos…
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Sk. Sarif Hassan, Debaleena Nawn, Nabanita Mukherjee, Arunava Goswami 等
2025-07-10T15:00:30Z
置信度 0.70
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2026-01-07T05:58:26Z
置信度 0.70
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Bihan Liu, Yuxi Zhang, Chunlong Zhang, Dan Tian
2024-10-09T17:35:46Z
置信度 0.70
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2024-11-15T04:07:03Z
置信度 0.70
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crossref
2026-01-07T05:58:26Z
置信度 0.70
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2008-05-23T14:37:37Z
置信度 0.70
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crossref
2026-01-07T05:58:26Z
置信度 0.70
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Abstract Deep learning sequence models trained on personalized genomics can improve variant effect prediction, however, applications of these models are limited by computational requirements for storing and reading large datasets. We address this with GenVarLo…
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David Laub, Aaron Ho, Jeff Jaureguy, Adam Klie 等
2025-01-17T07:25:49Z
置信度 0.70
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2026-01-07T05:58:26Z
置信度 0.70
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crossref
2025-04-30T04:36:51Z
置信度 0.70
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crossref
2026-02-04T15:59:33Z
置信度 0.70
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A pan-genome is a compilation of the common and unique genomes found in a given species. It incorporates the genetic information from all of the genomes sampled, producing a big and diverse set of genetic material. Pan-genomic analysis has various advantages o…
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Akansha Sarawad, Spoorti Hosagoudar, Prachi Parvatikar
2024-07-04T11:15:49Z
置信度 0.70
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2026-01-07T05:58:26Z
置信度 0.70
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crossref
2026-02-04T15:59:33Z
置信度 0.70
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Yoong Khean Khoo, Suci Wulandari, Marya Getchell, La Moe 等
2025-02-27T15:36:24Z
置信度 0.70
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crossref
Senjie Lin
2025-06-23T09:29:30Z
置信度 0.70
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Siyuan Shen, Renxuan Luo, Zhenhua Shao
2025-11-12T19:45:34Z
置信度 0.70
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crossref
2025-02-07T05:26:25Z
置信度 0.70
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Abstract Motivation Inference of candidate upstream regulators via motif enrichment analysis is a common step in the interpretation of genomic data. However, redundancy in motif databases can negatively impact predictive value, especially when relying on regre…
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Orsolya Lapohos, Gregory J. Fonseca
2025-08-01T21:35:13Z
置信度 0.70
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Daolei Zhang, Yujun Gan, Liang Le, Li Pu
2024-02-03T03:27:51Z
置信度 0.70
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Paolo Provero
2025-03-12T16:14:56Z
置信度 0.70
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crossref
Astrid Marchal, Vanessa Sancho-Shimizu, Laurent Abel, Jean-Laurent Casanova 等
2025-01-18T19:05:55Z
置信度 0.70
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crossref
2025-02-07T05:26:25Z
置信度 0.70
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Abstract Intrauterine adhesion (IUA) refer to persistent inflammation and fibrosis due to damaged or infected endometrium and eventually lead to dysfunction. This study aimed to explore the therapeutic effects of exosomes (Exos) derived from placental mesenchy…
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Lin Liang, Huidong Liu, Shaowei Wang
2025-03-27T11:08:15Z
置信度 0.70
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Polina Ukraintceva, Artem Bondaryuk, Rodion Sakhabeev
2025-11-12T07:56:45Z
置信度 0.70
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Background: Osteosarcoma (OS) is a highly aggressive bone tumor characterized by poor prognosis and frequent metastasis. Despite advances in treatment, the survival rate remains low. This study investigates the role of deubiquitinase (DUB) genes in OS to ident…
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Meng Zhang, Chunxin Cheng, Gang Liu
2025-08-18T07:23:13Z
置信度 0.70
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crossref
2025-09-20T00:42:18Z
置信度 0.70
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crossref
2026-01-07T05:58:26Z
置信度 0.70
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Background: The prognosis for lung adenocarcinoma (LUAD) is poor, and the recurrence rate is high. Thus, to evaluate patients’ prognoses and direct therapy choices, new prognostic markers are desperately needed. Methods: First, gene modules associated with LUA…
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Tian Zhang, Han Zhou
2025-03-23T12:29:25Z
置信度 0.70
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crossref
2025-02-20T06:56:11Z
置信度 0.70
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crossref
2025-02-20T06:56:11Z
置信度 0.70
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Background Ageing contributes to the onset of various diseases. It is accompanied by malfunctioning and deterioration of the body systems. Identifying the biomarkers for the prediction, diagnosis, management, or prognosis of ageing and biological ageing was th…
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Oluwafemi G. Oluwole, Ngalla Jillani, Afolake Arowolo, Solomon Umukoro
2025-10-31T07:05:50Z
置信度 0.70
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Background: Hepatocellular carcinoma (HCC) is a major cause of cancer mortality, with limited treatment options due to its high heterogeneity. SPP1 + tumor‐associated macrophages are emerging as key regulators of the tumor immune microenvironment and disease p…
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Suyang Yue, Qin Ding, Shanzhong Tan
2025-09-12T18:48:19Z
置信度 0.70
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Tess K. Fallon, Kristin A. Knouse
2025-02-24T11:41:15Z
置信度 0.70
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Albert Thembinkosi Modi
2024-11-30T16:34:43Z
置信度 0.70
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crossref
Joel Vizueta, Vadim A. Pisarenco, Julio Rozas
2025-08-19T08:13:14Z
置信度 0.70
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crossref
Subhayan Sur, Jayanta K. Pal, Soumya Shekhar, Palak Bafna 等
2025-03-30T13:22:04Z
置信度 0.70
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crossref
Mohammad Faizan, Anjuman Hussain, Pravej Alam
2025-09-26T05:44:33Z
置信度 0.70
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Liping Yin, Xiaofei Huang, Beibei Zhang, Qiyong Zhu 等
2025-01-14T03:22:49Z
置信度 0.70
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Even though there is strong evidence that exercise improves breast cancer patients′ quality of life, treatment tolerance, and survival, disparate research initiatives and uneven clinical acceptance underscore the need for a thorough synthesis of trends, partne…
crossref
Jian Li, LiYing Qiang, MingYue Jiao, BinBin Zhang
2025-10-23T11:35:00Z
置信度 0.70
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Objectives: The purpose of this study was to investigate the role of the ITGB1/FAK/AKT pathway in NRG‐1 in mediating the axonal growth of dorsal root ganglion neurons in Type I diabetic rats and to explore the mechanism of neuronal axonal regeneration. Result:…
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Peng Zhan, Hewei Xiong, Hongmei Zheng
2025-09-23T10:01:59Z
置信度 0.70
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Kritika Chugh, Zhenyu Xuan
2025-11-07T12:49:19Z
置信度 0.70
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Abstract Transcription factor (TF) chromatin immunoprecipitation followed by sequencing (ChIP-seq) is essential for identifying genome-wide TF-binding sites (TFBSs), and the collected datasets offer a variety of opportunities for downstream analyses such as in…
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Saeko Tahara, Haruka Ozaki
2025-09-30T01:01:34Z
置信度 0.70
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crossref
2025-02-20T06:56:11Z
置信度 0.70
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crossref
2025-02-20T06:56:11Z
置信度 0.70
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crossref
SATU NAHKURI, ULRICH H. WEIDLE
2025-08-29T18:40:10Z
置信度 0.70
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Bulbul Ahmed, Subham Dutta, Kousik Atta, Mritunjoy Barman
2025-07-15T21:31:36Z
置信度 0.70
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crossref
2025-02-07T05:26:25Z
置信度 0.70
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crossref
Shan Li, Yang Liu, Xun Wu, Qiuning Zhang 等
2025-07-25T05:04:32Z
置信度 0.70
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crossref
2025-02-07T05:26:25Z
置信度 0.70
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Abstract The major Bcl-2 family allows the evolutionarily conserved homology domain. Also, the domain can promote or block apoptosis. So, apoptosis is analytical in cancer growth and significant for therapy. In response to intracellular injury, several molecul…
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Shouhartha Choudhury
2025-06-24T13:49:13Z
置信度 0.70
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2025-09-17T17:15:31Z
置信度 0.70
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Nika Mansouri Ghiasi, Onur Mutlu
2025-12-05T05:42:09Z
置信度 0.70
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crossref
Alex Nehemia
2025-04-19T22:27:29Z
置信度 0.70
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crossref
Muin J. Khoury, Colleen M. McBride, Martina C. Cornel
2025-07-28T16:02:53Z
置信度 0.70