基因技术工具 · 全部实体（第 61 / 100 页）

本页收录第 6001–6100 条，共 10000 条 · 返回 基因技术工具 首页

• Oligodendrocyte senescence in Alzheimer's disease: multi-omics analysis code and curated result tables
  Analysis code and result tables for a multi-omics study of oligodendrocyte cellular senescence in Alzheimer's disease. The archive contains 53 analysis scripts (Python/R/shell), 7 publication figure scripts, 135 result tables (curated summary tables plus inter…
  datacite Luo, Zehua 2026 置信度 0.66 Alzheimer's diseasecellular senescenceoligodendrocytessplicing QTLMendelian randomization
• THE DYNAMIC GENOME THEORY OF HUMAN GENETICS (Volume 2)
  PREFATORY NOTE Volume II continues the integrated examination of human genetics established in Volume I. Whereas the first volume concentrated primarily on foundational principles and molecular organization, this volume extends the analysis toward functional g…
  datacite Karimi Baghmaleki, Majid 2026 置信度 0.66
• THE DYNAMIC GENOME THEORY OF HUMAN GENETICS (Volume 2)
  PREFATORY NOTE Volume II continues the integrated examination of human genetics established in Volume I. Whereas the first volume concentrated primarily on foundational principles and molecular organization, this volume extends the analysis toward functional g…
  datacite Karimi Baghmaleki, Majid 2026 置信度 0.66
• Explainable Multi-Modal Deep Learning Frame-work for Intelligent Healthcare Diagnosis
  Opacity in deep learning models poses a significant challenge in adopting AI models in healthcare as decisions need to be transparent. In this study, we propose XAI-MedFusion, a deep learning explainable multi-modal framework to enable intelligence in the diag…
  datacite Ramya S, I. R. Suganya 2026 置信度 0.66
• Explainable Multi-Modal Deep Learning Frame-work for Intelligent Healthcare Diagnosis
  Opacity in deep learning models poses a significant challenge in adopting AI models in healthcare as decisions need to be transparent. In this study, we propose XAI-MedFusion, a deep learning explainable multi-modal framework to enable intelligence in the diag…
  datacite Ramya S, I. R. Suganya 2026 置信度 0.66
• ClinGen Cardiomyopathy Expert Panel Specifications to the ACMG/AMP Variant Interpretation Guidelines for MYL3 Version 1.0
  This is a ClinGen Criteria Specification approved by the ClinGen Clinical Domain Working Group Oversight Committee and the ClinGen Variant Curation Expert Panel Review Committee. Usage subject to the Clinical Genome Resource's Terms of Use (https://clinicalgen…
  datacite Cardiomyopathy Variant Curation Expert Panel 2024 置信度 0.66 humanbiologygenomicsvariantvariant classification
• ClinGen Cardiomyopathy Expert Panel Specifications to the ACMG/AMP Variant Interpretation Guidelines for MYL3 Version 1.0
  This is a ClinGen Criteria Specification approved by the ClinGen Clinical Domain Working Group Oversight Committee and the ClinGen Variant Curation Expert Panel Review Committee. Usage subject to the Clinical Genome Resource's Terms of Use (https://clinicalgen…
  datacite Cardiomyopathy Variant Curation Expert Panel 2024 置信度 0.66 humanbiologygenomicsvariantvariant classification
• GEAR Genomics: a user-friendly, open-source web platform enabling interactive genomic analysis for molecular biologists
  The GEAR web applications are hosted at www.gear-genomics.com. This repository provides a GEAR web application snapshot for all the tools included in the publication.
  datacite Untergasser, Andreas, Fritz, Markus Hsi-Yang, Benes, Vladimir, Rausch, Tobias 2026 置信度 0.66 web-servergear-genomicsgenomicssanger-sequencingpcr
• GEAR Genomics: a user-friendly, open-source web platform enabling interactive genomic analysis for molecular biologists
  The GEAR web applications are hosted at www.gear-genomics.com. This repository provides a GEAR web application snapshot for all the tools included in the publication.
  datacite Untergasser, Andreas, Fritz, Markus Hsi-Yang, Benes, Vladimir, Rausch, Tobias 2026 置信度 0.66 web-servergear-genomicsgenomicssanger-sequencingpcr
• Reporting Item Standards for Education and Evaluation of Genomics ('RISE2 Genomics')
  This checklist was part of the Australian Genomics Workforce & Education Toolkit (https://www.australiangenomics.org.au/tools-and-resources/reporting-standards/) A lack of standards for reporting genomics education and evaluation limited replication of genomic…
  datacite Nisselle, Amy, Janinski, Monica, Martyn, Melissa, Dawson McClaren, Belinda 等 2026 置信度 0.66
• Reporting Item Standards for Education and Evaluation of Genomics ('RISE2 Genomics')
  This checklist was part of the Australian Genomics Workforce & Education Toolkit (https://www.australiangenomics.org.au/tools-and-resources/reporting-standards/) A lack of standards for reporting genomics education and evaluation limited replication of genomic…
  datacite Nisselle, Amy, Janinski, Monica, Martyn, Melissa, Dawson McClaren, Belinda 等 2026 置信度 0.66
• Fig. 11 in Genomics helps resolve allopatric COI (Cytochrome c oxidase subunit I) divergences in selected alpine Lepidoptera and allows for a taxonomic revision of the Symmoca signella species-complex (Autostichidae)
  Fig. 11. SYMMOCa SCHMidi sp. n., adult. Austria,Tyrol, female paratype. (LSID: urn:lsid:zoobank.org:act:048B5FCA-19DE-434B-8DC9- 212800E52BED).
  datacite Joshi, Mukta, Huemer, Peter, Espeland, Marianne, Mutanen, Marko 2026 置信度 0.66 BiodiversityTaxonomy
• Fig. 11 in Genomics helps resolve allopatric COI (Cytochrome c oxidase subunit I) divergences in selected alpine Lepidoptera and allows for a taxonomic revision of the Symmoca signella species-complex (Autostichidae)
  Fig. 11. SYMMOCa SCHMidi sp. n., adult. Austria,Tyrol, female paratype. (LSID: urn:lsid:zoobank.org:act:048B5FCA-19DE-434B-8DC9- 212800E52BED).
  datacite Joshi, Mukta, Huemer, Peter, Espeland, Marianne, Mutanen, Marko 2026 置信度 0.66 BiodiversityTaxonomy
• Supplementary material for Genomic drivers of coat pattern in West African leopards
  This deposit accompanies my research internship report "Genomic drivers of coat pattern in West African leopards." It contains the figures, the SLURM job scripts, and the raw tree files behind the analysis, so that anyone can trace every reported result back t…
  datacite Abdullah Al Asek 2026 置信度 0.66 Genomics
• Supplementary material for Genomic drivers of coat pattern in West African leopards
  This deposit accompanies my research internship report "Genomic drivers of coat pattern in West African leopards." It contains the figures, the SLURM job scripts, and the raw tree files behind the analysis, so that anyone can trace every reported result back t…
  datacite Abdullah Al Asek 2026 置信度 0.66 Genomics
• Temporal genomics Donax trunculus
  Clam fisheries along the Spanish coast have declined unevenly, while stock management often follows political rather than biological boundaries. To inform conservation and fishery management, this study used temporal seascape genomics to assess population stru…
  datacite Benestan, Laura 2026 置信度 0.66
• Temporal genomics Donax trunculus
  Clam fisheries along the Spanish coast have declined unevenly, while stock management often follows political rather than biological boundaries. To inform conservation and fishery management, this study used temporal seascape genomics to assess population stru…
  datacite Benestan, Laura 2026 置信度 0.66
• Developing a Mind Genomics Conceptual Framework for Public Health Nutrition Messaging on Ultra-Processed Food Consumption
  Ultra-processed foods (UPFs) have become an increasingly important public health nutrition concern worldwide because of their growing contribution to contemporary diets and their consistent association with adverse health outcomes. However, evidence indicates …
  datacite Howard Moskowitz 2026 置信度 0.66 Ultra-processed foods, Mind Genomics, Public health nutrition, Nutrition communication, Food literacy, Socioeconomic determinants.
• Developing a Mind Genomics Conceptual Framework for Public Health Nutrition Messaging on Ultra-Processed Food Consumption
  Ultra-processed foods (UPFs) have become an increasingly important public health nutrition concern worldwide because of their growing contribution to contemporary diets and their consistent association with adverse health outcomes. However, evidence indicates …
  datacite Howard Moskowitz 2026 置信度 0.66 Ultra-processed foods, Mind Genomics, Public health nutrition, Nutrition communication, Food literacy, Socioeconomic determinants.
• DNA Sequence Context and Genome Stability: Molecular Determinants of Mutation and DNA Repair
  Genome stability depends on continuous interaction between DNA damage, mutation formation, and repair.Local DNA sequence context shapes both processes in ways that remain incompletely understood. CpGdinucleotides, repetitive tracts, GC-rich regions, and non-B …
  datacite Mariam Fatima 2026 置信度 0.66 Sequence Analysis, DNAGenomicsDNA RepairDNA Repair/geneticsMutation
• Oligodendrocyte senescence in Alzheimer's disease: multi-omics analysis code and curated result tables
  Analysis code and result tables for a multi-omics study of oligodendrocyte cellular senescence in Alzheimer's disease. The archive contains 53 analysis scripts (Python/R/shell), 7 publication figure scripts, 135 result tables (curated summary tables plus inter…
  datacite Luo, Zehua 2026 置信度 0.66 Alzheimer's diseasecellular senescenceoligodendrocytessplicing QTLMendelian randomization
• Genetics: A Comprehensive Treatise on the Molecular Foundations of Heredity
  A comprehensive scholarly treatise on the molecular and cellular foundations of genetics. Published by the Scottish Science Society Press, Edinburgh, this work provides a rigorous treatment of Mendelian genetics, molecular genetics, gene regulation, genomics, …
  datacite Montgomery, Richard Murdoch 2026 置信度 0.66 geneticsmolecular geneticsgenomicsepigeneticsgene regulation
• Genetics: A Comprehensive Treatise on the Molecular Foundations of Heredity
  A comprehensive scholarly treatise on the molecular and cellular foundations of genetics. Published by the Scottish Science Society Press, Edinburgh, this work provides a rigorous treatment of Mendelian genetics, molecular genetics, gene regulation, genomics, …
  datacite Montgomery, Richard Murdoch 2026 置信度 0.66 geneticsmolecular geneticsgenomicsepigeneticsgene regulation
• samplesheet-parser: A Python library for parsing, validating, converting, and merging Illumina SampleSheet V1 and V2 files
  Open-source Python library providing format auto-detection, bidirectional V1/V2 conversion, structural and index validation, sheet diffing, and cross-project merging for Illumina SampleSheet files.
  datacite Kasaraneni, Chaitanya Krishna 2026 置信度 0.66 bioinformaticsIlluminaSampleSheetBCLConvertdemultiplexing
• Implementation of a flexible Oxford Nanopore sequencing platform for microbial genomics
  Oxford Nanopore sequencing technology is slowly revolutionising the entire microbiology field. Its ease of use and cost effective approaches coupled with long reads sequencing represent an essential and powerful tool. In the present thesis I have implemented a…
  datacite PINZAUTI, DAVID 2021 置信度 0.66
• Analysis code and input files for manuscript "Integrative phylogenomics uncovers hidden diversity and repeated cave colonizations in Dinaric pseudoscorpions"
  Analysis scripts and workflows for population genomic, demographic, and morphometric analyses. Includes Python and R code for dPCA, isolation by distance, geometric morphometrics, sexual dimorphism analysis, and Stairway Plot 2 demographic inference.
  datacite Hlebec, Dora, Enguídanos García, Alba, Machata, Marita, Arnedo, Miquel A. 2026 置信度 0.66 population genomicsddRAD-seqphylogenomicsgeometric morphometricsStairway Plot
• Analysis code and input files for manuscript "Integrative phylogenomics uncovers hidden diversity and repeated cave colonizations in Dinaric pseudoscorpions"
  Input files, analysis scripts and workflows for population genomic, demographic, and morphometric analyses. Includes Python and R code for dPCA, isolation by distance, geometric morphometrics, sexual dimorphism analysis, and Stairway Plot 2 demographic inferen…
  datacite Hlebec, Dora, Enguídanos García, Alba, Machata, Marita, Arnedo, Miquel A. 2026 置信度 0.66 population genomicsddRAD-seqphylogenomicsgeometric morphometricsStairway Plot
• Analysis code and input files for manuscript "Integrative phylogenomics uncovers hidden diversity and repeated cave colonizations in Dinaric pseudoscorpions"
  Input files, analysis scripts and workflows for population genomic, demographic, and morphometric analyses. Includes Python and R code for dPCA, isolation by distance, geometric morphometrics, sexual dimorphism analysis, and Stairway Plot 2 demographic inferen…
  datacite Hlebec, Dora, Enguídanos García, Alba, Machata, Marita, Arnedo, Miquel A. 2026 置信度 0.66 population genomicsddRAD-seqphylogenomicsgeometric morphometricsStairway Plot
• THE DYNAMIC GENOME THEORY OF HUMAN GENETICS (Volume 1)
  Human genetics has undergone a profound transformation over the course of the modern scientific era. What began largely as the study of inheritance and observable traits has developed into a vast interdisciplinary field encompassing molecular genetics, genomic…
  datacite Karimi Baghmaleki, Majid 2026 置信度 0.66
• THE DYNAMIC GENOME THEORY OF HUMAN GENETICS (Volume 1)
  Human genetics has undergone a profound transformation over the course of the modern scientific era. What began largely as the study of inheritance and observable traits has developed into a vast interdisciplinary field encompassing molecular genetics, genomic…
  datacite Karimi Baghmaleki, Majid 2026 置信度 0.66
• The diffuse-glioma interventional-trial landscape - molecular-era representation, global access, discontinuation, and eligibility restrictiveness: a scoping review and evidence-gap map.
  Scoping-review protocol (JBI methodology; PRISMA-ScR reporting). Review type. Scoping review (Arksey & O'Malley; Levac et al.; JBI 2020), reported per PRISMA-ScR. Descriptive charting and evidence-mapping only - no hypothesis testing, no meta-analysis, no …
  datacite Alexandru-Constantin Stan 2026 置信度 0.66 Laboratory and Basic Science Research Life SciencesMedical SciencesBioinformaticsOther Life SciencesDiseases
• breast-nac-reactome-workflow: A public-cohort Reactome pathway workflow for interpretable breast cancer neoadjuvant response prediction
  Reproducible release package for the manuscript: A Public-Cohort Reactome Pathway Workflow for Interpretable Prediction of Breast Cancer Neoadjuvant Response: A Retrospective Computational Study. The package includes processed non-identifiable result tables, f…
  datacite Li, Yafang, Zhao, Lina, Yang, Yiyi, Bian, Zihao 等 2026 置信度 0.66 breast cancerneoadjuvant therapypathological complete responseReactomepathway-level modeling
• breast-nac-reactome-workflow: A public-cohort Reactome pathway workflow for interpretable breast cancer neoadjuvant response prediction
  Reproducible release package for the manuscript: A Public-Cohort Reactome Pathway Workflow for Interpretable Prediction of Breast Cancer Neoadjuvant Response: A Retrospective Computational Study. The package includes processed non-identifiable result tables, f…
  datacite Li, Yafang, Zhao, Lina, Yang, Yiyi, Bian, Zihao 等 2026 置信度 0.66 breast cancerneoadjuvant therapypathological complete responseReactomepathway-level modeling
• samplesheet-parser: A Python library for parsing, validating, converting, and merging Illumina SampleSheet V1 and V2 files
  Open-source Python library providing format auto-detection, bidirectional V1/V2 conversion, structural and index validation, sheet diffing, and cross-project merging for Illumina SampleSheet files.
  datacite Kasaraneni, Chaitanya Krishna 2026 置信度 0.66 bioinformaticsIlluminaSampleSheetBCLConvertdemultiplexing
• Scholar and Zenodo Pipeline Validation Post
  This temporary post validates the combined Genomics x AI Google Scholar metadata and Zenodo DOI pipeline on a feature branch.
  datacite Editors, Genomics X AI 2026 置信度 0.66 workflowdoischolartesting
• Scholar and Zenodo Pipeline Validation Post
  This temporary post validates the combined Genomics x AI Google Scholar metadata and Zenodo DOI pipeline on a feature branch.
  datacite Editors, Genomics X AI 2026 置信度 0.66 workflowdoischolartesting
• Human Disease-Protein Mapping Dataset (HDPM-Dataset) from UniProt
  This dataset provides a structured mapping between human pathologies and their associated proteins, extracted from the UniProt bioinformatics portal. The collection comprises a randomly selected sample of 2,000 human diseases obtained from the official UniProt…
  datacite Trujillo de León, Said, Vilalta Welgraven, Thomas 2026 置信度 0.66 bioinformaticsuniprotproteinshuman diseasesweb scraping
• Human Disease-Protein Mapping Dataset (HDPM-Dataset) from UniProt
  This dataset provides a structured mapping between human pathologies and their associated proteins, extracted from the UniProt bioinformatics portal. The collection comprises a randomly selected sample of 2,000 human diseases obtained from the official UniProt…
  datacite Trujillo de León, Said, Vilalta Welgraven, Thomas 2026 置信度 0.66 bioinformaticsuniprotproteinshuman diseasesweb scraping
• Fluorescence-Activated Cell Sorting Depletes Macrophages and Triggers Inflammation in the Single-Cell Immune Landscape of Human Atherosclerosis.
  Atherosclerosis is characterised by a maladaptive immune response. Our understanding of this immune process has been advanced by using single-cell RNA sequencing (scRNA-seq) performed on human carotid plaques. The most widely used scRNA-seq platform utilises a…
  datacite Case, Ayden G, O'Brien, James W, Charlier, Fiona TW, Al-Hadithi, Ali BAK 等 2025 置信度 0.66 atherosclerosisimmunityinflammationmacrophages
• geisbert-lab/viral-genomics: v1.0
  First release to create DOI
  datacite Jackie Turcinovic 2026 置信度 0.66
• geisbert-lab/viral-genomics: v1.0
  First release to create DOI
  datacite Jackie Turcinovic 2026 置信度 0.66
• VitisGP:Vitis vinifera Genotype-Phenotype dataset
  VitisGP integrates genotype and phenotype information from three source cohorts and provides fixed feature ordering, prediction tasks, and grouped evaluation splits to facilitate reproducibility, and constitutes the frozen dataset release used for the experime…
  datacite Anonymous, Anonymous 2026 置信度 0.66 GenomicsPolymorphism, Single Nucleotide/geneticsMachine LearningWineClimate Change
• VitisGP:Vitis vinifera Genotype-Phenotype dataset
  VitisGP integrates genotype and phenotype information from three source cohorts and provides fixed feature ordering, prediction tasks, and grouped evaluation splits to facilitate reproducibility, and constitutes the frozen dataset release used for the experime…
  datacite Anonymous, Anonymous 2026 置信度 0.66 GenomicsPolymorphism, Single Nucleotide/geneticsMachine LearningWineClimate Change
• vartracker
  Track the persistence (or loss) of mutations during longitudinal sequencing. vartracker summarises VCFs and generates reports for longitudinal passaging experiments.
  datacite Foster, Charles 2026 置信度 0.66 bioinformaticsgenomicsmutation trackinglongitudinal analysisSARS-CoV-2
• vartracker
  Track the persistence (or loss) of mutations during longitudinal sequencing. vartracker summarises VCFs and generates reports for longitudinal passaging experiments.
  datacite Foster, Charles 2026 置信度 0.66 bioinformaticsgenomicsmutation trackinglongitudinal analysisSARS-CoV-2
• Digital Practical Manual: SBTTP-552 Laboratory Course in Genomics and Proteomics
  This digital practical manual covers 7 laboratory practicals for M.Sc. Biotechnology II Year students under SBTTP-552: Genomics and Proteomics, SRTMU Nanded. Topics include proteomics tools, structural predictions, phylogenetic analysis, BLAST, and sequence al…
  datacite Hajare, Sunil Tulshiram 2026 置信度 0.66 Genomics, Proteomics, Bioinformatics, BLAST, Phylogenetics, SRTMU, Practical Manual, Biotechnology
• Digital Practical Manual: SBTTP-552 Laboratory Course in Genomics and Proteomics
  This digital practical manual covers 7 laboratory practicals for M.Sc. Biotechnology II Year students under SBTTP-552: Genomics and Proteomics, SRTMU Nanded. Topics include proteomics tools, structural predictions, phylogenetic analysis, BLAST, and sequence al…
  datacite Hajare, Sunil Tulshiram 2026 置信度 0.66 Genomics, Proteomics, Bioinformatics, BLAST, Phylogenetics, SRTMU, Practical Manual, Biotechnology
• Using Realist Evaluation to Examine a Graduate Precision Health Program
  Precision health applies personalized data to improve outcomes (1) but ambiguity about what “precision” means may limit its reach. Current initiatives often emphasize data and measurement (genomics, digital health, predictive analytics) without equal attention…
  datacite Singh, Aanya, Patocka, Catherine 2025 置信度 0.66 PrecisionGraduate ProgramRealist
• Large-scale cross-cancer fine-mapping of the 5p15.33 region reveals multiple independent signals
  Genome-wide association studies (GWAS) have identified thousands of cancer risk loci revealing many 102 risk regions shared across multiple cancers. Characterizing the cross-cancer shared genetic basis can increase our understanding of global mechanisms of can…
  datacite Dennis, Joe, Easton, Douglas, Pharoah, Paul 2021 置信度 0.66 31 Biological Sciences3105 GeneticsColo-Rectal CancerBreast CancerGenetics
• GRPC (Genomics reproductib pipeline core ) "bioinformatique"
  Clés test (24h) demandable par mail :ouvrilnoah5@gmail.com Aperçu Le GRPC-Ω est une infrastructure génomique souveraine conçue pour le traitement de données de séquençage de nouvelle génération (NGS). Contrairement aux pipelines conventionnels, le GRPC-Ω repos…
  datacite Ouvril, Noah 2026 置信度 0.66 GenomicsNGS pipelineBioinformatique
• GRPC (Genomics reproductib pipeline core ) "bioinformatique"
  Clés test (24h) demandable par mail :ouvrilnoah5@gmail.com Aperçu Le GRPC-Ω est une infrastructure génomique souveraine conçue pour le traitement de données de séquençage de nouvelle génération (NGS). Contrairement aux pipelines conventionnels, le GRPC-Ω repos…
  datacite Ouvril, Noah 2026 置信度 0.66 GenomicsNGS pipelineBioinformatique
• ChemoSymEvo: lineage-specific metabolic retention in chemosynthetic symbionts
  Reproducible comparative-genomics workflow, compact derived data, and manuscript source materials supporting a lineage-stratified analysis of genome reduction and sulfur-energy architecture in marine chemosynthetic symbionts.
  datacite Li, Si 2026 置信度 0.66 chemosymbiosiscomparative genomicsgenome reductionreverse dissimilatory sulfite reductasesulfur oxidation
• ChemoSymEvo: lineage-specific metabolic retention in chemosynthetic symbionts
  Reproducible comparative-genomics workflow, compact derived data, and manuscript source materials supporting a lineage-stratified analysis of genome reduction and sulfur-energy architecture in marine chemosynthetic symbionts.
  datacite Li, Si 2026 置信度 0.66 chemosymbiosiscomparative genomicsgenome reductionreverse dissimilatory sulfite reductasesulfur oxidation
• Mapping implementation outcomes and delivery models of population-level genomics-informed breast and ovarian cancer risk assessment: scoping review
  The objective of this scoping review is to map population genomics-informed breast and ovarian cancer risk assessment programs, describe intervention characteristics and synthesize implementation outcome evidence. Population-level breast cancer risk assessment…
  datacite Olivia Braniff, Sibel Saya, Catherine Kennedy, Sharne Limb 等 2027 置信度 0.66 Medicine and Health Sciencesbreast cancergenomicsovarian cancerrisk stratification
• TF-DWGNet v1.0 (NAR GAB Publication Release)
  This release corresponds to the version of TF-DWGNet used in the published manuscript on NAR Genomics and Bioinformatics (2026) Preferred citation: If you use the TF-DWGNet idea or code in your research, please cite the associated publication: Yang, T., & Chen…
  datacite Yang, Tiantian 2026 置信度 0.66
• TF-DWGNet v1.0 (NAR GAB Publication Release)
  This release corresponds to the version of TF-DWGNet used in the published manuscript on NAR Genomics and Bioinformatics (2026) Preferred citation: If you use the TF-DWGNet idea or code in your research, please cite the associated publication: Yang, T., & Chen…
  datacite Yang, Tiantian 2026 置信度 0.66
• Benboubker et al_Elucidating the mechanism underlying the synergistic effect of ODCDLD1 using the Swiss Target Prediction tool and functional genomics
  Suppelmentary files to Benboubker et al. "Optimized multidrug therapy remodels the tumor microenvironment and enhances antitumor immunity in microsatellite-stable colorectal cancer".
  datacite Nowak-Sliwinska, Patrycja, Iwaszkiewicz, Justyna 2026 置信度 0.66
• Benboubker et al_Elucidating the mechanism underlying the synergistic effect of ODCDLD1 using the Swiss Target Prediction tool and functional genomics
  Suppelmentary files to Benboubker et al. "Optimized multidrug therapy remodels the tumor microenvironment and enhances antitumor immunity in microsatellite-stable colorectal cancer".
  datacite Nowak-Sliwinska, Patrycja, Iwaszkiewicz, Justyna 2026 置信度 0.66
• ITHindex: An integrated web-based platform for intratumor heterogeneity evaluation.
  Intratumor heterogeneity (ITH) is a critical factor influencing cancer progression, therapeutic response, and the development of drug resistance. Despite its importance, the lack of a definitive gold standard for ITH quantification has hindered consistent clin…
  pubmed Liu Y, Jiang Y, Xie W, Duan F 等 2026 Aug 置信度 0.82
• Machine Learning approaches for the detection of disease-causing variants in whole-genome data need to address the expression of functional genes.
  Gene-dosage combinations have been recognised as leading factors of disease. Given that those combinations may include dozens of genes, it is hypothesised that machine learning (ML) approaches may be useful in the classification of cases and controls and the i…
  pubmed Mapstone C, Handl J, Talavera D 2026 置信度 0.82
• From Infection Control to Healthcare System Resilience: Lessons Learned from SARS-CoV-2 Research in Healthcare Workers.
  The COVID-19 pandemic placed unprecedented pressure on healthcare systems and exposed healthcare workers (HCWs) to biological hazards, organizational pressures, and psychological strain. Evidence generated during the emergency shows that HCW protection cannot …
  pubmed Naddeo N, Faraci G 2026 Sep-Oct 置信度 0.82
• Machine learning-based classification model to distinguish tumor and tumor-free samples using synthetic plasma proteomic dataset.
  Tumor-Specific Peptides (TSPs) and Tumor-associated Overexpressed Proteins (TOPs) are promising biomarkers for cancer diagnosis and monitoring. TSPs arise from somatic mutations unique to tumor cells. Their detection in plasma through mass spectrometry-based p…
  pubmed Feizyab S, Bonetti G, Macchia A, Donato K 等 2026 Sep-Oct 置信度 0.82
• Plotgardener App: a graphical interface for publication-ready genomic visualization.
  Plotgardener is an R package used for generating high-quality genomic visualizations. Despite its broad range of functions and versatility, its reliance on code presents a barrier for many potential users. To address this, we developed a macOS desktop applicat…
  pubmed Vemuri RS, Berhanu A, Kenney GE, Parker SM 等 2026 Aug 28 置信度 0.82
• Biological Age Associates with Longitudinal Frailty-Related Functional Decline: The Health and Retirement Study.
  Epigenetic clocks have emerged as markers of biological aging. Understanding their association with age-related functional decline may provide insights into DNA-mediated mechanisms underlying frailty-related functional decline and reveal which clocks best asso…
  pubmed Prapiadou S, Kimball TN, Tan BYQ, Tack RWP 等 2026 Aug 28 置信度 0.82
• Bias in Genome-Wide Association Test Statistics Due to Omitted Interactions.
  Over the past two decades, genome-wide association studies (GWAS) enabled the discovery of thousands of variants associated with many complex human traits. However, conventional GWAS are still widely performed with linear models with the assumption that the ge…
  pubmed Yelmen B, Güler MN, Kollo T, Möls M 等 2026 Aug 28 置信度 0.82
• Short Sleep Duration Is Positively Associated With Traditional and Non-Traditional Markers of Adiposity and Cardiometabolic Risk in Individuals at Secondary Healthcare: A Cross-Sectional Study.
  This study aimed to investigate the associations between short and long sleep duration and traditional and non-traditional markers of adiposity and cardiometabolic risk. This is a cross-sectional study that enrolled secondary data of 937 men and women ≥…
  pubmed E Oliveira NMC, Filgueiras MS, Zanirate GA, Cândido FG 等 2026 Sep 15 置信度 0.82
• Differential Transcriptomic and Adhesion Responses of Human Periodontal Ligament Cells to Cyclic and Static Hydrostatic Pressure.
  Periodontal ligament (PDL) cells are continuously exposed to in vivo dynamic mechanical forces; however, how distinct temporal patterns of hydrostatic pressure (HP) regulate their mechanobiological responses remains unclear. This study aimed to elucidate …
  pubmed Miyano T, Kaku M, Sera T 2026 Sep 15 置信度 0.82
• Metrology of Nanoscale Objects Using Nanopores.
  Solid-state nanopore serves as a versatile tool for single-particle analysis of nanoscale objects, enabling the measurement of their geometrical and physicochemical properties with molecular precision. When a bias drives an analyte to translocate through …
  pubmed Li K, Yooprasertchuti K, Agrawal I, Marjanović T 等 2026 置信度 0.82
• Waist-to-height ratio as a practical indicator for screening pediatric metabolic dysfunction-associated steatotic liver disease in diverse populations and genetic backgrounds.
  Metabolic dysfunction-associated steatotic liver disease (MASLD) is the leading chronic liver disease in children and adolescents; this parallels the global obesity epidemic. The contribution of genetic susceptibility to pediatric MASLD, and its interaction wi…
  pubmed Liu YF, Wang YX, Li L, Shi D 等 2026 Aug 28 置信度 0.82
• The central role of the β-cell in diabetes: from monogenic forms to type 1, type 2, and gestational diabetes.
  Diabetes encompasses a heterogeneous group of metabolic disorders characterized by hyperglycemia resulting from inadequate insulin secretion and/or impaired insulin action. A central, common feature across all major forms of diabetes is the loss of functional …
  pubmed Chen Z, Pang H 2026 Aug 28 置信度 0.82
• The organellar biology of aging: A mitochondrial vantage.
  Aging is a progressive, multi-scale decline in physiological function driven by the accumulation of cellular and molecular damage. Mitochondrial dysfunction has emerged as an established hallmark of aging owing to its critical involvement in bringing about agi…
  pubmed Pala M, Nayak A, Rath B 2026 Aug 28 置信度 0.82
• Genome mining guided identification of new furo[3,2-c]pyridones phaeopyridones A-C from the endophytic fungus Phaeobotryon negundinis 12020.
  Three pairs of new furo[3,2-c]pyridone derivative racemates, named (±)-phaeopyridones A-C (1-3), together with two new compounds, berkeleyamide E (4), and phaeopyranone (5), were isolated from the endophytic fungus Phaeobotryon negundinis 12020, along wit…
  pubmed Ye K, Shi J, Wu H, Wang S 等 2026 Aug 28 置信度 0.82
• Myostatin in fish: current understanding of its characterization, function, and signaling pathways.
  Myostatin (Mstn), a secretory protein from the transforming growth factor-β (TGF-β) superfamily, is mostly present in skeletal muscle across vertebrates. The mstn gene exhibits a conserved genomic structure consisting of three exons and two introns…
  pubmed Wang Y, Deng L, Li T, Liu L 等 2026 Aug 28 置信度 0.82
• Detailed re-analysis of satellitome mapping facilitated by the telomere-to-telomere (T2T) assembly of bread wheat genome.
  The satellitome of Triticum aestivum cv. Chinese Spring consists of 36 satellite DNA (satDNA) families that were previously molecularly characterized and chromosomally mapped. The recent release of a complete gap-free telomere-to-telomere (T2T) assembly of the…
  pubmed Garrido-Ramos MA, Prieto P 2026 Aug 28 置信度 0.82
• Characterization of disomic alien addition lines from an intersubgeneric cross between Glycine max and G. tomentella and phenotypic variation within those lines and their progenies.
  Disomic alien addition lines (DAALs, 2n = 42) were obtained from an intersubgeneric cross between Glycine max [L.] Merr. cv. Dwight (2n = 40, G1G1) and Glycine tomentella Hayata (PI 441001, 2n = 78, D3D3CC). These DAAL…
  pubmed Wang S, Singh R, Battu G, Belaffif M 等 2026 Aug 28 置信度 0.82
• Development of a rapid antiviral screening assay based on GFP reporter virus of bovine enterovirus.
  In recent years, bovine enterovirus (BEV) has been increasingly associated with diarrhea in cattle in China, posing new challenges for disease control in the cattle industry. However, the mechanisms underlying BEV pathogenesis and virulence remain poorly under…
  pubmed Zhang Y, Li X, Yao H, Ji C 等 2026 Aug 28 置信度 0.82
• Complete telomere-to-telomere genome assembly of Guazuma ulmifolia uncovers evolutionary mechanisms, drought adaptation, and flavonoid biosynthesis.
  The first T2T reference genome of Guazuma ulmifolia is reported, which serves as a core genomic resource for stress adaptation research and stress-tolerant breeding in cacao wild relatives. Climate change, particularly increased incidence of drought, poses a m…
  pubmed Dorjee T, Cui Y, Liu B, Richardson JE 等 2026 Aug 28 置信度 0.82
• Genome characterization of two novel mitoviruses and a negative-sense single-stranded RNA mycovirus from the phytopathogenic fungus Clarireedia jacksonii.
  Clarireedia jacksonii is a phytopathogenic fungus responsible for dollar spot disease in turfgrass worldwide. In this study, we characterized the complete genome sequences of three novel mycoviruses isolated from C. jacksonii isolate MBCT-836 using next-genera…
  pubmed Sakuta K, Mabuchi T, Urayama SI, Netsu O 等 2026 Aug 28 置信度 0.82
• Comparative transcriptomics reveals hormone signaling and MADS-box genes in divergent development of inflorescences and tendrils in grapevine lateral shoots.
  Hormone signaling and MADS-box genes regulate grapevine tendril and inflorescence growth divergence, offering molecular insights for managing tendril growth. Grapevine (Vitis vinifera L.) tendrils and inflorescences are homologous organs; however, their diverg…
  pubmed Ni Y, Bian Y, Xie Z, Li Y 2026 Aug 28 置信度 0.82
• Human pegivirus 1 in healthy blood donors and in acute febrile patients from Mato Grosso, Midwestern Brazil.
  The association between Human Pegivirus 1 (HPgV-1, Pegivirus hominis, family Hepaciviridae) with disease etiology remains unclear, yet this virus is widely distributed among people exposed to contaminated blood. This study aimed to identify the prevalence and …
  pubmed Pavan E, Carrasco MM, Pavón JAR, Marin L 等 2026 Aug 28 置信度 0.82
• Nuclear diversity in Charophyceae revealed by fluorescence staining and its implications for genome size estimation.
  We established a protocol for reliable nuclear visualization in Charophyceae, revealed diverse nuclear organization across cell types and species, and identified suitable cells for genome size estimation via flow cytometry. Charophyceae are multicellular green…
  pubmed Böhm J, Peters J, Herburger K, Schubert H 2026 Aug 28 置信度 0.82
• Construction of a novel reporter strain indicating inhibition of cell wall biosynthesis.
  The WalRK two-component system monitors cell wall biosynthesis, and its activity decreases when biosynthesis is inhibited. As WalRK is essential for many Gram-positive bacteria, including Staphylococcus aureus and Bacillus subtilis, directly inhibiting WalK wo…
  pubmed Karcher ML, Siskowski A, Müller C, Engel L 等 2026 Aug 28 置信度 0.82
• Unveiling the interactions between design optimization, modeling strategies, and spatial analysis in genomic selection.
  Partially-replicated designs are more efficient than fully-replicated ones. They can be further enhanced through optimization and present positive synergy with fully-efficient models and 2D P-splines. In plant breeding, traditional field trials rely on balance…
  pubmed Fernández-González J, Comadran Trabal J, Haquin B, Allard A 等 2026 Aug 28 置信度 0.82
• Approximating prediction error variances and reliabilities in a multiple-trait genomic prediction model using Monte Carlo sampling.
  We evaluated four existing Monte Carlo-based methods for approximating prediction error variances and reliabilities in a multiple-trait genomic prediction model. All four methods yielded consistent approximations of the exact values. Genomic prediction models,…
  pubmed Heikkilä A, Strandén I, Lidauer MH, Nordhausen K 等 2026 Aug 28 置信度 0.82
• Afirma Xpression Atlas Alteration Status Is Associated with Malignancy Risk in Indeterminate Thyroid Nodules.
  Molecular testing with the Afirma Genomic Sequencing Classifier (GSC) is commonly used to refine the diagnosis of thyroid nodules with indeterminate cytology. The Afirma Xpression Atlas (XA) is a whole-transcriptome RNA-sequencing platform that reports express…
  pubmed Peng TD, Hughes EG, Kim J, Tseng CH 等 2026 Aug 28 置信度 0.82
• A capsid hinge region in European hepatitis E virus links mutations to genotype, virion surface properties, and environmental circulation.
  Hepatitis E virus (HEV) exhibits genetic diversity associated with distinct public health outcomes and circulation patterns across interconnected human and environmental reservoirs. Most studies have focused on genome-wide diversity, revealing relationships be…
  pubmed Kasmi S, Sautrey G, Hartard C, Quilès F 等 2026 Aug 28 置信度 0.82
• Semi-automated strain engineering and screening in the thermophilic fungus Myceliophthora thermophila for recombinant protein production.
  Thermophilic filamentous fungi are widely used for cellulase production at elevated temperatures; however, efficient recombinant protein production in these organisms remains limited because construction and screening of large transformant populations remain d…
  pubmed Gong C, Yang X, Zhao X, Gou F 等 2026 Aug 28 置信度 0.82
• Fine-scale structural diversification among closely related Legionella pneumophila isolates from a bath-associated environmental reservoir.
  Legionella pneumophila populations within environmental reservoirs can exhibit genomic diversity, complicating source attribution during outbreak investigations. Core genome single-nucleotide variant (cgSNV)-based approaches are widely used for identifying clo…
  pubmed Nakajima N, Jinnai M, Okamura A, Date Y 等 2026 Aug 28 置信度 0.82
• Complete genome sequence of Pasteurella multocida subsp. septica isolated from a sepsis patient in Thailand.
  Pasteurella multocida is a rare cause of human infection most often associated with animal bites or scratches. We report the complete genome sequence of Pasteurella multocida subsp. septica strain 0092 recovered from the blood culture of a sepsis patient in Na…
  pubmed Kinnonkok S, Tinthalang K, Rujidamp J, Khemla S 等 2026 Aug 28 置信度 0.82
• Genomes of cressdnaviricots and phixviricots in a freshwater lake sample from Arizona, USA.
  A viral metagenomic analysis of a 40 ml water sample from a small freshwater lake near Flagstaff, Arizona, USA, resulted in the identification of 295 circular viral genome sequences. Of these, 126 are members of Cressdnaviricota and 169 of Phixviricota phyla.
  pubmed Custer JM, Kraberger S, Levi G, Schmidlin K 等 2026 Aug 28 置信度 0.82
• Minimal organism JCVI-syn3.0, an engineered derivative of Mycoplasma mycoides, encodes an assortment of unrecognized membrane transporters and immunity factors.
  In 2016, researchers at the J. Craig Venter Institute produced JCVI-Syn3.0, a derivative of Mycoplasma mycoides subsp. capri Large Colony strain GM12 with a re-engineered, minimized genome. The minimal synthetic genome of 532 kbp encodes 473 genes, selected fr…
  pubmed Mushegian AR, Yamamoto PK, Torikai N, Arakawa K 2026 Aug 28 置信度 0.82
• Oxygenaging: A Physiological Framework for Geroscience.
  The stepwise movement of oxygen from the atmosphere to the mitochondria, the "oxygen cascade", is one of the most tightly regulated systems in physiology. Despite decades of mechanistic study, it has remained quite unexplored in Geroscience. This oversight sho…
  pubmed Donega S, Fishbein KW, Dominelli P, Herman AB 等 2026 Sep 置信度 0.82
• AGG repeat expansion and aggregation of BIN1 in multiple system atrophy.
  Multiple system atrophy is a fatal, sporadic α-synucleinopathy characterized by glial cytoplasmic inclusions in oligodendrocytes. No causative gene for multiple system atrophy has been identified to date. Whole-genome sequencing was performed for a patie…
  pubmed Kume K, Kurashige T, Itabashi T, Akagi A 等 2026 Aug 28 置信度 0.82
• Genetic Risk of Cardiovascular Disease Among People With No Standard Modifiable Risk Factors.
  pubmed Farah R, Sui Y, Jemma Cho SM, Natarajan P 等 2026 Aug 28 置信度 0.82
• Low-Normal Hemoglobin Concentrations and Clinical Outcomes in Heart Failure.
  The World Health Organization (WHO) defines anemia as hemoglobin concentration <12 g/dL in women and <13 g/dL in men. Although widely used clinically, these thresholds were based on distributions in healthy populations rather than on outcomes. Whether th…
  pubmed Chimura M, Pellicori P, Docherty K, Claggett BL 等 2026 Aug 28 置信度 0.82
• Genetically Mediated Differences in LDL Cholesterol and Risk of Venous Thromboembolism.
  Venous thromboembolism (VTE) is a common and clinically significant cardiovascular condition. Although low-density lipoprotein (LDL) cholesterol is causally linked to atherosclerotic disease, its role in VTE remains unclear. Meta-analyses of randomized trials …
  pubmed Sui Y, Kany S, Khurshid S, Supriami K 等 2026 Aug 4 置信度 0.82
• HFpEF-ABA Score and Finerenone in Patients With Heart Failure and Mildly Reduced or Preserved Ejection Fraction: Insights From the FINEARTS-HF Trial.
  The HFpEF-ABA score is a simple diagnostic tool developed to estimate the probability of heart failure with preserved ejection fraction (HFpEF) using age, body mass index, and history of atrial fibrillation.
  pubmed Ono R, Docherty KF, Henderson AD, Claggett BL 等 2026 Aug 27 置信度 0.82
• Pre-Cambrian origin of envelope-carrying retrotransposons in metazoans.
  Retrotransposons or endogenous retroviruses (ERVs) essentially carry open reading frames of gag and pol , which are utilized to selfishly replicate themselves in the host germline genome. One rare example of ERVs that additionally carry envelope genes is Ty3/g…
  pubmed Chary S, Hayashi R 2026 Aug 28 置信度 0.82
• Adaptive Variation Amid High Gene Flow Across a Broad Latitudinal Gradient in the Reef-Building Honeycomb Worm, Sabellaria alveolata.
  Climate change is already altering, and will continue to reshape, the persistence and spatial structure of marine populations. Understanding metapopulation connectivity and local adaptation is therefore critical for identifying both vulnerable populations and …
  pubmed Wilson EJ, Knights AM, Firth LB, Corporeau C 等 2026 Sep 置信度 0.82
• Mixed evidence that dosage sensitive genes drive global dosage compensation in flour beetles.
  Heteromorphic sex chromosomes create inherent gene dosage differences between males and females because one sex carries a single copy of the X chromosome while the other carries two. Many species have evolved mechanisms that equalize X-linked gene expression b…
  pubmed Pau SH, Ramesh B, Bracewell RR, Demuth JP 2026 Aug 28 置信度 0.82