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• Sensory Systems of Animals
  crossref Mark Hollins 2024-08-28T19:10:46Z 置信度 0.70
• The Important Role of Systems Biology in Neuroscience and Neurology and Its Associated Diseases
  crossref M. Haripriyaa, K. Suthindhiran 2024-05-16T19:01:51Z 置信度 0.70
• Role of noncoding RNAs in host-pathogen interactions: a systems biology approach
  crossref Kartavya Mathur, Ananya Gupta, Varun Rawat, Vineet Sharma 等 2024-02-23T09:05:28Z 置信度 0.70
• A COMPREHENSIVE REVIEW OF THE AYURVEDIC CONCEPT OF PRAKRITI AND ITS PARALLELS WITH MODERN PERSONALITY FRAMEWORKS
  Background: In Ayurvedic medicine, every individual is fundamentally unique based on their inherent physical and psychological constitution, a foundational concept known as Prakriti, which is definitively determined at the time of conception and remains unchan…
  datacite Dr. Raghu Krishna M. M.*1, Prof. Dr. Chhaju Ram Yadav2, Dr. Rashmi Prakash Gurao3 2026 置信度 0.66
• From Ward to Waterway: Tracking the Environmental Dissemination of blaCTX-M Resistance Genes in Sub-Saharan Africa.
  Background: blaCTX-M is the dominant extended-spectrum beta-lactamase gene in clinical Escherichia coli and Klebsiella pneumoniae across sub-Saharan Africa, with prevalence exceeding 97% in some Nigerian hospitals. However, the environmental release and dissem…
  datacite Chiamaka Juliet Okeke 2026 置信度 0.66 Medicine and Health SciencesLife SciencesAntimicrobial ResistanceESBLEnvironmental health
• Effect of Aloe Vera Gel Coating on Postharvest Quality and Shelf Life of Guava (Psidium guajava L.): A Systematic Review and Meta-Analysis
  Guava (Psidium guajava L.) is a climacteric fruit of significant economic importance known for its high content of vitamin C, minerals, carotenoids and polyphenolic compounds. Guava, however, has a high respiration rate and quick ripening, which is accelerated…
  datacite Laiba Razaq, Shaista Abbas, Farheen Shabbir, Ayesha Arshad 等 2026 置信度 0.66 Plant SciencesAgricultureLife Sciences(Psidium guajava L.)Aloe Vera
• Heavy-metal contamination in freshwater fish of the Indus River basin, Pakistan: a systematic review and meta-analysis of tissue burdens, spatiotemporal trends, and human-health risk
  Background: Freshwater fish from the Indus River basin are an important dietary protein source in Pakistan, yet the basin receives substantial industrial, agricultural and municipal effluent. Numerous single-site studies have quantified heavy-metal burdens in …
  datacite Muhammad Ammar 2026 置信度 0.66 Life SciencesEcology and Evolutionary BiologyIndus Riverfreshwater fishheavy metals
• Lower-Limb Functional Inter-Limb Asymmetry and Subsequent Lower-Limb Injury Risk in Athletes: A Systematic Review and Multilevel Meta-Analysis of Prospective Cohort Studies
  This systematic review and meta-analysis will evaluate whether baseline functional inter-limb asymmetry of the lower extremities is prospectively associated with subsequent lower-limb injury in athletes. Eligible studies will include prospective cohort studies…
  datacite 李浩南 2026 置信度 0.66 KinesiologySports MedicinePublic HealthMedicine and Health SciencesLife Sciences
• Experimental Models and Biological Outcomes of SIRT3–SIRT5 in Mammalian Aging and Cellular Senescence: A Scoping Review
  This scoping review aims to systematically map mammalian preclinical evidence on experimental models and biological outcomes involving SIRT3, SIRT4, and SIRT5 in biological aging and cellular senescence. It will include mammalian animal models and mammalian-de…
  datacite dwi nur ahsani, ika fidianingsih 2026 置信度 0.66 Medicine and Health SciencesLife SciencesSIRT3 SIRT4 SIRT5 mitochondrial sirtuins aging cellular senescence mammalian models preclinical research cell culture scoping review
• Search Strategy for Removal of Foreign Body Airway Obstruction
  This is the search strategy for a Structured Review on removal of foreign body airway obstruction conducted by the International Liaison Committee on Resuscitation's First Aid Task Force.
  datacite Bradley, Richard 2025 置信度 0.66 Medicine, Health and Life SciencesAirway Obstruction (TH, MO)First Aid (MT)Heimlich ManeuverRespiration, Artificial
• Cold, hot and contrast water immersion for post-exercise central and cognitive recovery: a scoping review of the thermal-direction × exposure-duration dissociation
  This project registers the protocol for a scoping review examining how three thermal water-immersion modalities - cold-water immersion (CWI), hot-water immersion (HWI) and contrast water therapy (CWT) - affect central nervous system and cognitive function duri…
  datacite Chengqiang Zhang 2026 置信度 0.66 KinesiologySports MedicineMedicine and Health SciencesLife SciencesMedical Specialties
• The use of large language models to support peer reviewers in emergency medicine journals: protocol for a prospective meta-analysis
  This prospective meta-analysis (PMA) will evaluate the effect of large language model (LLM) support for peer reviewers on the quality of peer-review reports in Emergency Medicine (EM) journals, compared with standard peer review without LLM support. The aim is…
  datacite William Kenneth Milne, David Nunan, Nicholas J DeVito 2026 置信度 0.66 Emergency MedicineScholarly CommunicationPhysical Sciences and MathematicsMedicine and Health SciencesLife Sciences
• TEXTBOOK OF BIOCHEMISTRY
  Welcome to Introduction to Biochemistry and Clinical Chemistry. This textbook has been meticulously designed to bridge the gap between fundamental biochemical principles and their practical applications in clinical diagnostics. Biochemistry is the language of …
  datacite Dr MAGESH MOHAN, Dr B VIJAYAKUMAR, Ms S NARMATHA, Dr C BUVANA 等 2026 置信度 0.66
• TEXTBOOK OF BIOCHEMISTRY
  Welcome to Introduction to Biochemistry and Clinical Chemistry. This textbook has been meticulously designed to bridge the gap between fundamental biochemical principles and their practical applications in clinical diagnostics. Biochemistry is the language of …
  datacite Dr MAGESH MOHAN, Dr B VIJAYAKUMAR, Ms S NARMATHA, Dr C BUVANA 等 2026 置信度 0.66
• Cyclic mechanical stretch and cardiac fibroblast activation in vitro: a systematic review and exploratory meta-analysis
  Title Cyclic mechanical stretch and cardiac fibroblast activation in vitro: a systematic review and exploratory meta-analysis Registration summary This registration describes a prospective protocol for an independent systematic review and exploratory meta-anal…
  datacite Dawen Wang 2026 置信度 0.66 BioinformaticsDiseasesMedicine and Health SciencesCardiovascular DiseasesLife Sciences
• Interactions between Nanoplastics and Heavy Metals in Freshwater Ecosystems: A Systematic Review of Adsorption Mechanisms, Combined Toxicity, and Ecological Risk
  This systematic review critically synthesizes experimental and observational evidence on nanoplastic–heavy metal interactions in freshwater ecosystems, focusing on adsorption, speciation, transport, bioavailability, combined toxicity, bioaccumulation, trophic …
  datacite Hana Bouguern 2026 置信度 0.66 Life Sciencesnanoplastics heavy metals freshwater ecosystems nanoplastic-metal interactions combined toxicity ecotoxicology adsorption bioavailability bioaccumulation Trojan horse effect oxidative stress environmental risk assessment freshwater pollution plastic pollution metal pollution environmental fate trophic transfer ecological risk systematic review PRISMA 2020
• Homeostasis in Input-Output Networks: Structure, Classification and Applications
  Homeostasis is concerned with regulatory mechanisms, present in biological systems, where some specific variable is kept close to a set value as some external disturbance affects the system. Mathematically, the notion of homeostasis can be formalized in terms …
  datacite Antoneli, Fernando, Golubitsky, Martin, Jin, Jiaxin, Stewart, Ian 2024 置信度 0.66 Molecular Networks (q-bio.MN)Combinatorics (math.CO)Dynamical Systems (math.DS)Biological Physics (physics.bio-ph)FOS: Biological sciences
• The Use of Physiological Biomarkers to Assess Occupational Stress Among Healthcare and Non-Healthcare Workers: A Scoping Review Protocol
  Occupational stress has emerged as an important public health and occupational health concern across diverse working environments globally. It may affect employees’ psychological well-being, physical health, work performance, productivity, and, in healthcare s…
  datacite Lufuno Makhado, ADIVHAHO SEMETHI, Thendo Gertie Makhado 2025 置信度 0.66 Medical SciencesPsychiatry and PsychologyPublic HealthMedicine and Health SciencesLife Sciences
• Circulating MOTS-c is not a comparable analyte: a systematic appraisal of measurement validity across human studies
  MOTS-c is a 16-amino-acid mitochondrial-derived peptide increasingly reported as a circulating biomarker across metabolic, cardiovascular, renal and respiratory disease. Almost all such clinical reports rely on commercial immunoassays whose analytical validity…
  datacite Brandon Thomas Mysliwiec 2026 置信度 0.66 BiochemistryPhysiologyMedicine and Health SciencesLife SciencesEndocrinology
• Scoping Review: The current scope of applications deploying computer vision in the assessment of children with neurodevelopmental disorders
  This scoping review aims to map the current landscape of how computer vision methods are applied in the assessment of children with neurodevelopmental conditions. It identifies the computer vision methods used, the features extracted, the targets of evaluation…
  datacite Fatima Karim, Azra Delpak, Navreen Kaur Sandhu, Zul Merali 等 2026 置信度 0.66 Medicine and Health SciencesLife SciencesSocial and Behavioral SciencesScoping review, Neurodevelopmental Disorders, Computer Vision, Adaptive Function, Assessment, Autism Spectrum Disorder, ADHD
• Effects of mangiferin and Mangifera indica leaf extract supplementation on metabolic and physiological parameters and sports performance.
  This scoping review will systematically map the available evidence on the effects of supplementation with mangiferin and Mangifera indica leaf extract on metabolic parameters, physiological responses, and sports performance. Mangiferin is a bioactive polypheno…
  datacite Giuseppe Potrick Stefani, Manuela Dreissig Pera 2026 置信度 0.66 Plant SciencesSports SciencesPhysiologyDietetics and Clinical NutritionNutrition
• Age-Related Variation in Alu and LINE-1 DNA Methylation in Humans: A Systematic Review
  This systematic review will examine age-related variation in aggregate Alu and LINE-1 DNA methylation in humans. Eligible evidence will include cross-sectional and longitudinal studies of healthy individuals and separately extractable healthy control participa…
  datacite jirapan thongsroy 2026 置信度 0.66 Medicine and Health SciencesLife SciencesAgingAlu elementsChronological age
• Research to examine and recommend future national infrastructures in research, development and experiments
  Samuel Neaman Institute won in 2019, a tender to perform research for the National Committee for Research Infrastructures of the MOLMOP in the Ministry of Science and Technology. The purpose of the study was to examine the needs for infrastructures for researc…
  datacite Daphne Getz, Vered Gilad, Sima Tziperfal 2019 置信度 0.66
• Linking Social Cognition to Quality of Life in Temporal Lobe Epilepsy: A Systematic Review
  Systematic review evaluating the relationship between social cognition (emotion recognition and theory of mind) and quality of life in adults with temporal lobe epilepsy who have not undergone epilepsy surgery. Note: This registration is retrospective — the se…
  datacite Jakub Žalud, Viktoria Ogurcakova, Jana Amlerova, Tomáš Nikolai 2026 置信度 0.66 Clinical PsychologyMedicine and Health SciencesCognitive PsychologySocial and Behavioral SciencesPsychology
• Associations Between Habitat Type and Species Composition and Relative Abundance of Medium- and Large-Sized Terrestrial Mammals in Ethiopia: A Systematic Review
  his systematic review will synthesize evidence on the association between habitat type and species composition and relative abundance of medium- and large-sized terrestrial mammals in Ethiopia. It will compare mammal assemblages across forest, woodland, grassl…
  datacite Yohans Ayalew 2026 置信度 0.66 Life SciencesEthiopia; terrestrial mammals habitat association; species composition; relative abundance; biodiversity; wildlife conservation; systematic review
• From microfluidics to hierarchical hydrogel materials
  Over the past two decades, microfluidics has made significant contributions to material and life sciences, particularly via the design of nano-, micro- and mesoscale materials such as nanoparticles, micelles, vesicles, emulsion droplets, and microgels. Unmatch…
  datacite Weigel, Niclas, Li, Yue, Fery, Andreas, Thiele, Julian 2023 置信度 0.66 540Cellular materialsHierarchical materialsHydrogelsMicrofluidics
• Preclinical Evidence for Phytochemicals as Cathepsin K Inhibitors in Osteoporosis Models: A Systematic Review
  Cathepsin K (CTSK) is a lysosomal cysteine protease predominantly expressed in osteoclasts and plays a crucial role in the degradation of type I collagen, the major organic component of the bone matrix. Excessive CTSK activity contributes to increased bone res…
  datacite Vo Duy Nhan, Reysan Cosas, Chanthawat Patikorn, Krittikan Chanpaisaeng 2026 置信度 0.66 Natural Products Chemistry and PharmacognosyMedical SciencesPharmacologyMedical Molecular BiologyPharmacy and Pharmaceutical Sciences
• Do texto histórico ao computador: metodoloxía e criterios de recompilación do Coruña Corpus
  Este poster ofrece unha descrición das características e os principios metodolóxicos do Coruña Corpus of English Scientific Writing (CC), un corpus a gran escala, diacrónico e especializado, deseñado para investigar a evolución do inglés científico no período …
  datacite Moskowich, Isabel, Crespo, Begoña 2026 置信度 0.66 Coruña CorpusLingüística de corpusrepresentatividadeequilibrioXML
• Do texto histórico ao computador: metodoloxía e criterios de recompilación do Coruña Corpus
  Este poster ofrece unha descrición das características e os principios metodolóxicos do Coruña Corpus of English Scientific Writing (CC), un corpus a gran escala, diacrónico e especializado, deseñado para investigar a evolución do inglés científico no período …
  datacite Moskowich, Isabel, Crespo, Begoña 2026 置信度 0.66 Coruña CorpusLingüística de corpusrepresentatividadeequilibrioXML
• Neuroimaging methods in Aromatherapy research of human studies: a scoping review protocol
  Aromatherapy has been increasingly investigated for its potential effects on cognition, emotion, stress, behavior, and clinical outcomes; however, the neurobiological mechanisms underlying these effects remain only partially understood. Several neuroimaging an…
  datacite Nathânia Frutuoso, Kinulpe Honorato Sampaio, Lourdes Godinho, Arthur Sales Honorio 2026 置信度 0.66 Medical SciencesCognitive NeuroscienceNeurosciencesMedicine and Health SciencesLife Sciences
• Determinants of tuberculosis preventive therapy initiation and completion among people living with HIV in sub-Saharan Africa: a systematic review and meta-analysis
  A systematic review and meta-analysis of the determinants of tuberculosis preventive therapy initiation and completion among adolescents and adults living with HIV in sub-Saharan Africa. Six databases were searched to 15 August 2026 with no language restrictio…
  datacite GODWIN ADJEI VECHEY, Joel Torvike, Pius Afrane, Millicent Edem Akpaka 等 2026 置信度 0.66 Immunology and Infectious DiseaseClinical EpidemiologyImmunology of Infectious DiseasePublic HealthMedicine and Health Sciences
• Injury severity and burden in adult Rugby Union 15s players during match and training exposure: a systematic review and meta-analysis
  This project will systematically review injury severity and injury burden in adult Rugby Union 15s players during match and training exposure. Where outcome definitions and precision data are sufficiently comparable, a meta-analysis will be conducted separatel…
  datacite 宋俊仁 2026 置信度 0.66 Medicine and Health SciencesLife SciencesRugby Union 15s、 injury severity、 injury burden、 match exposure、 training exposure、 systematic review、 meta-analysis、sports medicine
• Conserved Molecular Responses to Heat Stress in Cold-Water Fishes: A Systematic Review of Transcriptomic and Metabolomic Evidence
  This project presents a systematic review entitled **“Conserved Molecular Responses to Heat Stress in Cold-Water Fishes: A Systematic Review of Transcriptomic and Metabolomic Evidence.”** The review was undertaken to determine whether transcriptomic and metabo…
  datacite Asare Derrick 2026 置信度 0.66 Life SciencesClimate adaptationClimate warmingCold-water fishesComparative physiology
• Rol de las cucarachas sinantrópicas como vectores de parásitos de importancia médica en el ser humano: Protocolo de una revisión de alcance (scoping review)
  Esta revisión de alcance (scoping review) tiene como objetivo mapear la evidencia científica disponible sobre el rol de las cucarachas sinantrópicas como vectores de parásitos de importancia médica para el ser humano, considerando las especies de cucarachas y …
  datacite Sergio Altamirano Pinto, Renata Alonso, Valentina Paz Vargas González 2026 置信度 0.66 ParasitologyImmunology and Infectious DiseaseParasitic DiseasesDiseasesMedicine and Health Sciences
• Preclinical Efficacy of Recombinant Human Platelet-Derived Growth Factor-BB in Experimental Diabetic Wound Healing: A Systematic Review and Meta-analysis of Animal Studies
  This retrospective registration documents the finalized methodology of a systematic review and meta-analysis evaluating the preclinical efficacy of exogenously administered recombinant human platelet-derived growth factor-BB (rhPDGF-BB), including becaplermin …
  datacite José Luis Muñoz_Carrillo, Oscar Gutiérrez-Coronado, Edrei López Hernández, Rosalinda Gutiérrez Hernández 等 2026 置信度 0.66 Medicine and Health SciencesLife Sciencesanimal modelsbecaplermindiabetic wound healing
• The application, adaptation, and outcomes of Namaste Care for adults with advanced illness and their caregivers: a scoping review
  Project Overview and Background This scoping review investigates the implementation, adaptation, and outcomes of Namaste Care for adults with advanced, life-limiting illnesses and their caregivers across various end-of-life care settings. Namaste Care is a per…
  datacite Leung Lai Yin, Professor CHAN Yue Lai, Helen 2025 置信度 0.66 Medicine and Health SciencesGeriatric NursingNursingAdvanced illnessCaregivers
• Mechanisms of hippocampal CA2 pyramidal neuron resistance to seizure-induced injury and death: protocol for a systematic review and mechanistic evidence map
  This prospective registration describes the protocol for a systematic review and mechanistic evidence map of the mechanisms associated with the reported relative resistance of hippocampal CA2 pyramidal neurons to seizure-induced neuronal injury and death. The …
  datacite Bruno Ponciano da Silva, silene maria araujo de lima 2026 置信度 0.66 Medicine and Health SciencesLife SciencesMolecular and Cellular NeuroscienceNeuroscience and Neurobiologyepilepsy
• Métodos de tratamento de fezes de cães para obtenção de produto estável, sanitariamente seguro e com potencial de uso agronômico: revisão sistemática com mapeamento de escopo
  Este projeto consiste em uma revisão sistemática com mapeamento de escopo destinada a identificar, organizar e sintetizar as evidências científicas sobre métodos de tratamento de fezes de cães, incluindo compostagem, bokashi, fermentação e outras tecnologias r…
  datacite Núbia Soares Santos, Ariane Flávia do Nascimento 2027 置信度 0.66 Plant SciencesPhysical Sciences and MathematicsAgricultural ScienceEnvironmental EngineeringLife Sciences
• Near-Infrared Spectroscopy for Monitoring Industrial Cheese Ripening: A Scoping Review
  Background: Industrial cheese ripening involves dynamic changes in proteolytic, lipolytic, moisture, texture, and sensory properties that remain conventionally monitored using destructive, time-consuming reference methods. Near-infrared (NIR) spectroscopy offe…
  datacite Woska Pires da Costa, Ana Michell García Varela, Danyla Rafaela Oliveira Batista, Vania Silva Carvalho 等 2026 置信度 0.66 Physical Sciences and MathematicsFood ProcessingAnalytical ChemistryDairy ScienceLife Sciences
• Evaluation of the Management of Iron Tablet Supplementation Program for Adolescent Girls in Indonesia: A Scoping Review
  This project contains the protocol and supporting materials for the scoping review entitled “Evaluation of the Management of Iron Tablet Supplementation Program for Adolescent Girls in Indonesia: A Scoping Review.” The review aims to map and synthesize evidenc…
  datacite Noerfitri Noerfitri, Rohayati, Nanda Aula Rumana, Erni Astutik 等 2026 置信度 0.66 Public HealthNutritionMedicine and Health SciencesLife SciencesMental and Social Health
• DABEER (Special Issue on Routes, Roots and Remembered Homes) June 2026
  This issue examines how South Asian migration and diaspora have generated rich literary, cultural and intellectual traditions shaped by memory, belonging, displacement and transnational identity. Diasporic literature from the region engages deeply with questio…
  datacite Ahmad Naved, Yasir 2026 置信度 0.66 Arts & Humanities
• DABEER (Special Issue on Routes, Roots and Remembered Homes) June 2026
  This issue examines how South Asian migration and diaspora have generated rich literary, cultural and intellectual traditions shaped by memory, belonging, displacement and transnational identity. Diasporic literature from the region engages deeply with questio…
  datacite Ahmad Naved, Yasir 2026 置信度 0.66 Arts & Humanities
• THE SILENT PANDEMIC: THE PANDEMIC OF LONELINESS IN THE 21ST CENTURY
  ABSTRACT This paper imagines the phenomenon of loneliness, which has become one of the hallmarks of the 21 st century, not as a personal psychopathology, but as a social product, as an expression of the structural changes that characterise late modern societie…
  datacite UZUN, HASAN, SOCIOLOGICAL THEORY 2026 置信度 0.66
• THE SILENT PANDEMIC: THE PANDEMIC OF LONELINESS IN THE 21ST CENTURY
  ABSTRACT This paper imagines the phenomenon of loneliness, which has become one of the hallmarks of the 21 st century, not as a personal psychopathology, but as a social product, as an expression of the structural changes that characterise late modern societie…
  datacite UZUN, HASAN, SOCIOLOGICAL THEORY 2026 置信度 0.66
• Mapping the implementation of Wolbachia-based interventions for dengue control: a scoping review
  Dengue is the most widespread arboviral disease globally, and Wolbachia-based interventions have emerged as a promising biological approach to its control, in which Aedes aegypti mosquitoes carrying Wolbachia bacteria are released to reduce dengue transmission…
  datacite Septiara Putri, Eleanor Grieve, Olivia Wu 2026 置信度 0.66 Medicine and Health SciencesLife SciencesWolbachiadengueimplementation
• Conocimientos corporales en estudiantes enredados a través de plataformas digitales
  RESUMENLa relación cotidiana con las plataformas digitales ha conllevado a giros epistémicos con respecto al cuerpo humano(no)humano y los límites natural y artificial. Esto ha impactado en los distintos ámbitos de la vida, por lo tanto, no deja fuera a las y …
  datacite Carrillo, Claudia Fonseca 2026 置信度 0.66 Conocimientoscuerpoestudiantes escolaresplataformas digitalesagencia
• Conocimientos corporales en estudiantes enredados a través de plataformas digitales
  RESUMENLa relación cotidiana con las plataformas digitales ha conllevado a giros epistémicos con respecto al cuerpo humano(no)humano y los límites natural y artificial. Esto ha impactado en los distintos ámbitos de la vida, por lo tanto, no deja fuera a las y …
  datacite Carrillo, Claudia Fonseca 2026 置信度 0.66 Conocimientoscuerpoestudiantes escolaresplataformas digitalesagencia
• Child life and psychosocial preparation interventions for children with autism spectrum disorder undergoing invasive medical procedures: a scoping review mapping intervention components, sensory adaptations, and outcomes
  Children with autism spectrum disorder (ASD) frequently undergo invasive or high-stress medical procedures (venipuncture, injections, urinary catheterisation, dental treatment, anaesthetic induction, and diagnostic imaging) and experience disproportionately hi…
  datacite Qianqian He, Rong Hu, Haixia Wang 2026 置信度 0.66 Pediatric NursingMedicine and Health SciencesMedical SpecialtiesPediatricsSocial and Behavioral Sciences
• Blue-Carbon Stocks and Coastal-Protection Values of West and Central African Mangroves: A Systematic Review Protocol
  This systematic review synthesises quantitative evidence on carbon stocks and coastal-protection values of mangrove ecosystems in West and Central Africa (Mauritania to Angola), with tropical Atlantic and global comparators for benchmarking. Three questions st…
  datacite GARDAWHEH GAD BOE 2026 置信度 0.66 Marine BiologyPhysical Sciences and MathematicsOceanography and Atmospheric Sciences and MeteorologyLife SciencesEcology and Evolutionary Biology
• Studie: Global skalierbare Informationsmedizin durch die kostenlose aimeim App und Hybrid-Validierung über die aimeim Klinik Uruguay: Diffusionsmodell, Closed-Loop-Personalisierung und mikroskopisch-biologische Evidenzpfade
  Autor: Dieter W. Liedtke Jahre: 1970-2026 Lizenz: CC BY 4.0 Abstract Diese Studie entwickelt ein wissenschaftlich überprüfbares Modell zur globalen Verbreitung der kostenlosen aimeim App als mehrsprachiges (100+ Sprachen) Informations- und Gesundheitssystem un…
  datacite Liedtke, Dieter Walter 2026 置信度 0.66
• Studie: Global skalierbare Informationsmedizin durch die kostenlose aimeim App und Hybrid-Validierung über die aimeim Klinik Uruguay: Diffusionsmodell, Closed-Loop-Personalisierung und mikroskopisch-biologische Evidenzpfade
  Autor: Dieter W. Liedtke Jahre: 1970-2026 Lizenz: CC BY 4.0 Abstract Diese Studie entwickelt ein wissenschaftlich überprüfbares Modell zur globalen Verbreitung der kostenlosen aimeim App als mehrsprachiges (100+ Sprachen) Informations- und Gesundheitssystem un…
  datacite Liedtke, Dieter Walter 2026 置信度 0.66
• Experimental Therapeutics for Radiation-Induced Oral Mucositis: A Scoping Review of Preclinical Evidence and Translational Gaps
  This project contains the protocol and supporting materials for a scoping review of Experimental Therapeutics investigating radiation-induced oral mucositis. The scoping review aims to systematically review the available preclinical evidence, including animal …
  datacite SNEHA RAJA, Dr. JAYASUTHA JAYRAM, Dr. SATISH SRINIVAS KONDAVEETI, Dr. SUJATHA KUPPUSAMY 等 2026 置信度 0.66 Medicine and Health SciencesLife SciencesAnimal StudiesOral MucositisPreclinical Studies
• DEHP Migration from PVC Medical Devices and Toxicity: A Systematic Review — Data Extraction Tables
  Data extraction tables from a systematic review on DEHP migration from polyvinyl chloride (PVC) medical devices and its toxic effects. Includes in vivo migration studies (n=10), ex vivo migration studies (n=8), and toxicity studies (n=33). Registration: INPLAS…
  datacite DARY LUZ MENDOZA MEZA, Harley Gregorio Benavidez 2026 置信度 0.66 Medicine and Health SciencesLife SciencesDEHPPRISMA-2020PVC
• Extraterrestrial Aquaculture: Its Conceptual Foundations and Scope
  Extraterrestrial aquaculture (“space aquaculture”) is increasingly discussed as a distinct interdisciplinary research field at the intersection of aquatic biology, astrobiology, space systems engineering, and related space life and environmental sciences. This…
  datacite MUTAF, Aliye Bedriye, TÜRKER, Ali 2026 置信度 0.66 Astrobiologyextraterrestrial aquaculturecandidate species selectionrecirculating aquaculture systems (RAS)bioregenerative life support system (BLSS)
• Extraterrestrial Aquaculture: Its Conceptual Foundations and Scope
  Extraterrestrial aquaculture (“space aquaculture”) is increasingly discussed as a distinct interdisciplinary research field at the intersection of aquatic biology, astrobiology, space systems engineering, and related space life and environmental sciences. This…
  datacite MUTAF, Aliye Bedriye, TÜRKER, Ali 2026 置信度 0.66 Astrobiologyextraterrestrial aquaculturecandidate species selectionrecirculating aquaculture systems (RAS)bioregenerative life support system (BLSS)
• AI Appointment Scheduling Built Around Healthcare Operations
  A patient appointment call may sound simple, but the operational workflow behind it is not. This visual presentation from Gyan Solutions Health & Life Sciences explores how an AI-enabled appointment scheduling assistant can support real clinic operations. It i…
  datacite Allen, Nathan 2026 置信度 0.66 AI appointment schedulinghealthcare appointment schedulingvoice AIclinic schedulingpatient call automation
• Antioxidant Compounds in Microalgae and Cyanobacteria: A Sustainable Source of Bioactive Molecules.
  The search for antioxidant compounds from aquatic or marine environments to cope with the harmful effects of reactive oxygen species (ROS) is one of the major challenges in contemporary blue biotechnology. Among marine microorganisms, microalgae have emerged a…
  pubmed Gómez-Villegas P, Díaz-Santos E, Rengel R, Molina-Márquez A 等 2026 Aug 21 置信度 0.82
• Isolated Hypoglossal Nerve Palsy Associated with Internal Carotid Artery Dissection: A Systematic Review.
  Background : Isolated hypoglossal nerve palsy is a rare neurological condition with a broad differential diagnosis. Although neoplastic disorders are the most common cause, internal carotid artery dissection (ICAD) is an uncommon but clinically important and p…
  pubmed Frisina P, Panebianco V, Valentini F, Iacuzio A 等 2026 Aug 14 置信度 0.82
• Assessment of Upper Limb Function Using Virtual Reality Technologies in Adults with Neurological Disorders: A Systematic Review.
  Background: Virtual reality (VR) is increasingly being explored as a tool for upper limb (UL) assessment in adults with neurological disorders. This review synthesizes the available evidence on VR-based UL assessments by analyzing their psychometric properties…
  pubmed Bel-Lacoma J, Aguilera-Rubio Á, Cano-de-la-Cuerda R 2026 Jul 24 置信度 0.82
• Nicotinamide Mononucleotide Adenylyltransferase 1 and NAD(+) Homeostasis in Neuroprotection and Aging.
  Nicotinamide adenine dinucleotide (NAD + ) is a fundamental metabolic cofactor and signaling molecule that supports redox reactions, DNA repair, chromatin regulation, stress adaptation, inflammation, and neuronal maintenance. Age-associated NAD + decline has b…
  pubmed Sun Y, Li B, Qian Z 2026 Aug 21 置信度 0.82
• Application of Metabolomics in the Exploration of Bioactive Compounds and Drug Development from Medicinal Fungi.
  Medicinal fungi are important sources of natural medicines and are rich in a wide range of secondary metabolites with significant bioactivities, including terpenoids and alkaloids. As one of the core tools of systems biology, metabolomics has developed from si…
  pubmed Tong Y, Tang C, Jia B, Tang H 等 2026 Aug 16 置信度 0.82
• Application of Metabolomics in Defence Responses of Brassica Crops.
  Brassica crops, encompassing globally important vegetables and oilseeds, face severe threats from diverse biotic and abiotic stresses. Plant secondary metabolites constitute the chemical foundation of defence, and metabolomics has emerged as an effective syste…
  pubmed Li Y, Lu J 2026 Aug 10 置信度 0.82
• AI-Assisted Spatial Metabolic Engineering in Plants: Integrating Flux Design, Spatial Omics, and Synthetic Biology.
  Background: Plant synthetic biology reprograms metabolic networks for the sustainable production of high-value compounds. Recent computational advances incorporate machine learning to accelerate the design-build-test-learn (DBTL) cycle, enabling more predictab…
  pubmed Chen H, Yang J, Du M 2026 Jul 23 置信度 0.82
• Low-Molecular-Weight Polyols as Key Factors in Sulfur- and Borate-Mediated Protomembrane Formation Before the RNA World.
  The emergence of biological membranes was a critical step in the origin of cellular life because compartmentalization enabled molecular concentration, selective interactions, and increasingly complex chemical evolution. While fatty acids are widely considered …
  pubmed Dembitsky VM 2026 Aug 15 置信度 0.82
• Association Between Cross-Sectional Geometry and Cyclic Fatigue Resistance of Nickel-Titanium Endodontic Instruments: A Systematic Review.
  This systematic review aimed to evaluate whether cross-sectional geometry is associated with cyclic fatigue resistance of nickel-titanium (NiTi) endodontic instruments and to identify the geometric and materials-related features most frequently associated with…
  pubmed Kubatska M, Kensy J, Cygankiewicz J, Gajewska M 等 2026 Aug 12 置信度 0.82
• Biomimetic Dermal Substitutes for Skin Reconstruction: Advances in Scaffold Design, Biological Integration, and Clinical Performance.
  Reconstructive surgery still faces various challenges when dealing with the reconstruction of complex skin defects, regardless of their origin (e.g., trauma, burns). Split-thickness autologous skin grafts remain the gold standard; however, this technique comes…
  pubmed Zărnescu BMM, Lungu II, Niculescu AG, Scafa Udriște A 等 2026 Aug 12 置信度 0.82
• Advances in Key Genetic Elements and Strategies for High-Yield Heterologous Protein Expression in Komagataella phaffii.
  Komagataella phaffii has emerged as an important eukaryotic microbial cell factory for the production of industrial enzymes, biopharmaceuticals, and food-related proteins owing to its rapid growth, capacity for eukaryotic post-translational modifications, and …
  pubmed Han R, Hu R, Liu A, Yu X 等 2026 Aug 15 置信度 0.82
• Therapeutic Target Mapping to Advance Drug Repurposing for Cardiovascular Disease: A Perspective from an Explanted Heart Biobank.
  Background: Although cardiovascular disease (CVD) significantly impacts the quality of life of millions of patients worldwide, the high costs of developing new drugs and conducting clinical trials for CVD hinder therapeutic development in this field. Repurposi…
  pubmed Ng C, Singhera GK, Chang EC, Samra A 等 2026 Aug 3 置信度 0.82
• Cardiac Contractility Modulation and Arrhythmic Burden in Heart Failure: Mechanistic Rationale, Clinical Evidence, and Future Perspectives.
  Cardiac contractility modulation (CCM) is an implantable device-based therapy that delivers biphasic, non-excitatory electrical signals to the ventricular myocardium during the absolute refractory period. By enhancing contractile performance without inducing d…
  pubmed Palermi A, Saraullo S, Faustino M, Sacchetta D 等 2026 Aug 1 置信度 0.82
• Predicting circRNA-Drug Sensitivity Using Integrated Hybrid Graph and Molecular Features.
  Circular RNAs (circRNAs) are a class of covalently closed RNA molecules that exhibit high stability and play crucial roles in tumorigenesis and therapeutic response. Increasing evidence highlights their potential as biomarkers for drug sensitivity and resistan…
  pubmed Wang Y, Shen W, Li J, Hu J 等 2026 Aug 26 置信度 0.82
• The cGAS-STING pathway in inflammaging and neuroinflammation.
  Cytosolic DNA surveillance through the cGAS-STING axis is a central component of innate immune defense, coupling the detection of mislocalized DNA to downstream inflammatory responses. Beyond its established role in antiviral immunity, dysregulated cGAS-STING …
  pubmed Zhang C, Liu C, Zhao Y, Wang H 等 2026 Aug 21 置信度 0.82
• The intersection of chemokine signaling with the hallmarks of cancer in glioblastoma.
  Glioblastoma, IDH-wildtype, is characterized by diffuse invasion, profound immunosuppression, treatment resistance, and near-inevitable recurrence. Although canonical genetic alterations establish malignant capacity, they do not fully explain how glioblastoma …
  pubmed Chojak R, Turunen JR, Drewes NB, Koutah L 等 2026 Aug 26 置信度 0.82
• Synthetic transcriptional repression systems in plants.
  Transcriptional repression is a fundamental regulatory mechanism that enables precise control of gene expression in response to developmental signals and environmental stimuli. Synthetic biology can leverage this process within plants to engineer programmable …
  pubmed Clark LA, Pfotenhauer AC, Lenaghan SC, Stewart CN Jr 2026 Aug 26 置信度 0.82
• An aging essential 8: closing the gap between geroscience and the public it serves.
  Longevity science has advanced faster than the public's capacity to interpret it. Biological age tests, longevity clinics, and consumer wearables now reach millions of people, yet no shared framework exists to tell an individual what those numbers mean or what…
  pubmed Grimolizzi F 2026 Aug 26 置信度 0.82
• Connector Design and Pontic Span Length as Determinants of Mechanical Performance in Zirconia Fixed Dental Prostheses: A Systematic Review.
  Objectives : To systematically evaluate the influence of connector design and pontic span length on the mechanical performance of zirconia fixed dental prostheses (FDPs). Methods : A systematic review was conducted according to PRISMA 2020 guidelines (8). Elec…
  pubmed Ordoñez Balladares A, Chauca-Bajaña L, Adolfi D, Teulé-Trull M 等 2026 Aug 8 置信度 0.82
• A CSF-1R Ig4-5 Domain-Targeting Antibody for the Treatment of Idiopathic Pulmonary Fibrosis.
  Idiopathic pulmonary fibrosis (IPF) is closely associated with fibroblast proliferation, macrophage polarization, and the accumulation of extracellular matrix (ECM). Targeting CSF-1R can rebalance macrophages, reduce ECM deposition, and block pro-fibrotic sign…
  pubmed Luo W, Shao Z, Wang T, Lok K 等 2026 Aug 11 置信度 0.82
• Advances in Machine Learning-Assisted Optical Sensing Arrays for Disease Diagnosis.
  Optical sensing arrays have emerged as transformative tools for disease diagnosis, offering low-cost, rapid, and multiplexed fingerprint detection capabilities. However, the high-dimensional and complex data generated by these arrays pose significant challenge…
  pubmed Sun X, Sun H, Wang B, Lin H 2026 Jul 31 置信度 0.82
• Regulatory T Cell (Treg): Central Orchestrator of Immune Homeostasis.
  Regulatory T cells (Tregs) play a pivotal role in maintaining immune homeostasis by exerting precise control over immune activation, suppressing excessive responses, and facilitating tissue repair. These specialized CD4+ T cells, characterized by FOXP3 express…
  pubmed Salam MA, Al-Amin MY, Sudarshan K, Whalen N 等 2026 Aug 15 置信度 0.82
• From Neurovascular Compression to Neural Hyperexcitability: Integrating Microanatomy, Electrophysiology, and Computational Neuroscience to Understand Trigeminal Neuralgia and Hemifacial Spasm.
  Neurovascular compression syndromes (NVCS), including trigeminal neuralgia (TN) and hemifacial spasm (HFS), are characterized by disabling symptoms caused by vascular compression of cranial nerves. Although microvascular decompression is an established treatme…
  pubmed Okuhata H, Aihara M, Oya S, Nagai R 等 2026 Aug 10 置信度 0.82
• AI-Ready Multimodal Wearable Biosensors Beyond Glucose: Biofluid Sampling, Sensor Fusion, and Clinical Translation.
  Continuous glucose monitoring has established that a molecular signal can be repeatedly measured in daily life and translated into clinically meaningful action. The next frontier is broader: wearable biosensors that monitor metabolites, electrolytes, hormones,…
  pubmed Kızılkurtlu AA, Akpek A 2026 Aug 18 置信度 0.82
• Chemiresistive Gas Sensors for the Detection of Listeria monocytogenes Metabolite: Recent Progress and Challenges.
  Listeria monocytogenes (LM), one of the most virulent foodborne pathogens, poses a serious threat to public health due to its strong environmental adaptability and high pathogenicity. Rapid, sensitive, and real-time detection of LM is of great importance. Chem…
  pubmed Feng B, Wei J 2026 Aug 13 置信度 0.82
• Recent Progress in Nanoparticle-Based Biosensors for Monitoring Shigella spp. in Food Safety: A Critical Review.
  Shigella is a foodborne bacterial pathogen with a low infectious dose and significant public health impact. Culture-based and molecular techniques provide reliable identification but are time-consuming. Nanoparticle-based biosensors offer sensitive, selective,…
  pubmed Savas S, Gharibzahedi SMT 2026 Aug 11 置信度 0.82
• Tumor Microenvironment-on-a-Chip: Construction and Application in Traditional Chinese Medicine Anti-Tumor Therapy.
  Cancer is the second leading cause of death worldwide, and tumor heterogeneity remains a major obstacle to effective therapy. In vitro reconstruction of the tumor microenvironment (TME) is particularly challenging because of its complexity, dynamic nature, and…
  pubmed Sheng Y, Chen W, Zhang Z, Cui Z 等 2026 Jul 30 置信度 0.82
• MSC-Hydrogel Composite Systems for Knee Cartilage Repair and Osteoarthritis: A Systematic Review.
  Background: MSC-hydrogel composite systems were developed to overcome the poor cell retention and limited durability of conventional marrow stimulation and suspension-based MSC delivery. A rigorous synthesis of the clinical evidence is lacking. Objectives: To …
  pubmed Raimagambetov Y, Suiindik B, Makhmetova M, Saginova D 等 2026 Aug 13 置信度 0.82
• Flavanone Intake and Cardiometabolic Outcomes: A Synthesis of Meta-Analytic Evidence from Cohort and Clinical Studies.
  Flavanones, a subclass of flavonoids predominantly found in citrus fruits, have attracted growing interest for their potential role in cardiometabolic health. While evidence linking overall flavonoid intake to cardiometabolic benefits is relatively consistent,…
  pubmed Doaei S, Gil-Lespinard M, Elban Z, Gholamalizadeh M 等 2026 Aug 12 置信度 0.82
• How Do Oral Medications, Botulinum Toxin Use, and Treatment Burden Change after Deep Brain Stimulation for Dystonia?
  Deep brain stimulation (DBS) is an established therapy for dystonia; however, the long-term trajectory of adjunctive treatment burden, including oral medications and botulinum toxin (BoNT) injections, and the likelihood of achieving medication-free status rema…
  pubmed Kamo H, Leone E, Kumar R, Antilla C 等 2026 Aug 26 置信度 0.82
• Engineering peptides into antibodies-opportunities and strategies for therapeutic innovation.
  Peptides and antibodies occupy complementary therapeutic niches. Peptides offer compact size and high-affinity recognition of difficult targets, whereas antibodies provide exquisite specificity, long serum half-life, and effector functions. Here we review stra…
  pubmed Wang J, Romaniuk R, Svilenov HL 2026 Aug 26 置信度 0.82
• A developmental biologist's guide to mechanics.
  Developmental biology seeks to explain how living systems self-organize into functional, robust forms. While molecular and genetic approaches have revealed how biological information is encoded and processed, they often do not explain how this information is t…
  pubmed Cao J, Chiappori A, Landiech S, Clément R 等 2026 Aug 15 置信度 0.82
• Tumor-Associated Macrophages in the Chemoresistant Microenvironment of Gastric Cancer: Key Mechanisms and Intercellular Crosstalk.
  Gastric cancer (GC) remains a leading cause of cancer-related mortality, with chemoresistance posing a critical barrier to effective treatment. Tumor-associated macrophages (TAMs), particularly the immunosuppressive M2-polarized subset, are emerging as pivotal…
  pubmed Abdul-Rahman SY, Shareef A, Jyothi SR, Nayak PP 等 2026 Sep 置信度 0.82
• Estimating treatment effects in clinical studies of Alzheimer's disease: What are estimands and why do we need them?
  In clinical studies, it is scientifically important, and a regulatory expectation, that objectives be translated into key clinical questions by specifically defining treatment effects to be estimated. Estimands are part of a structured framework, as presented …
  pubmed Hendrix S, Mallinckrodt C, Abschneider RM, Atri A 等 2026 Aug 置信度 0.82
• Therapeutic gases and the Nrf2/Keap1 pathway: direct thiol modification vs. indirect modulation.
  The nuclear factor erythroid 2-related factor 2/Kelch-like Ech-associated protein 1 (Nrf2/Keap1) pathway is a central homeostatic module that integrates oxidant, electrophilic, inflammatory, and metabolic signals into adaptive transcriptional programs. In para…
  pubmed Xiao T, Xia C, Huang L, Li Y 等 2026 Aug 26 置信度 0.82
• Medicine's 'Basic' Mistake: How the Molecular Revolution Displaced an Entire Category of Inquiry.
  The integration of molecular biology in medicine represents a remarkable achievement of modern science. Nonetheless, the success of molecular methods reshaped medicine's epistemology over time such that biological explanation came to mean explanation exclusive…
  pubmed Horwitz RI, Concato J 2026 Aug 置信度 0.82
• What to Expect in 2026-2027: Important Health Economics and Outcomes Research Topics.
  An infographic titled 'What to Expect in 2026-2027: Important Health Economics and Outcomes Research (HEOR) Topics' outlines five key HEOR areas. 1. HEOR Models: AI is transforming HEOR with advanced data, but needs validation to avoid errors. 2. Real World Ev…
  pubmed Abraham I, Hiligsmann M, Lee KKC, Colombo GL 等 2026 置信度 0.82
• Evaluation of Depression in Adults With and Without Type 2 Diabetes Mellitus: A Comparative Study.
  Depression is a common psychiatric disorder frequently associated with type 2 diabetes mellitus (T2DM) and negatively impacts quality of life and disease outcomes.
  pubmed Hamza M, Chan S, Sharif MU, Ahmed N 等 2026 Jul 置信度 0.82
• Non-transport functions of motor proteins in corticogenesis.
  Cerebral cortex development is a tightly coordinated sequence of interconnected processes: proliferation of neural progenitors, neuronal migration, neurite differentiation, axonal pathfinding, and synaptogenesis. Traditionally, motor proteins-dyneins, kinesins…
  pubmed Mitina N, Medyanik A, Tarabykin V, Kondakova E 2026 置信度 0.82
• Biological treatments for asthma and chronic obstructive pulmonary disease.
  Asthma and chronic obstructive pulmonary disease (COPD) are highly prevalent heterogeneous airway diseases in which a subset of patients with severe disease have a disproportionate share of morbidity and mortality, largely through exacerbations. Major immunolo…
  pubmed Tejwani V, Siddharthan T, Majumdar U, Hatipoğlu U 等 2026 置信度 0.82
• From Fleming to Lifeline: theatre, narrative and public engagement in antimicrobial stewardship.
  Antimicrobial resistance (AMR) is a defining global health threat, yet public understanding of why antibiotic stewardship matters remains limited and statistical communication alone is rarely sufficient. Arts-based interventions offer a complementary route to …
  pubmed Elshenawy RA, Brown M 2026 Aug 置信度 0.82
• Genome-resolved insights into hydrocarbon-transforming and nitrate-reducing microbial communities from deep petroleum reservoir cores of the Nashpa Oil Field, Pakistan.
  Microbial communities from deep subsurface petroleum reservoirs are adapted to hydrocarbon-rich, oxygen-limited, and physicochemically extreme environments. However, genome-resolved knowledge of petroleum reservoir microbiomes from Pakistan remains largely une…
  pubmed Tayyaba S, Amin A, Zulfiqar S, Ahmed I 2026 置信度 0.82
• Bioactive components of medicinal-food homology substances alleviating constipation via gut microbiota modulation: a review.
  Functional constipation (FC) is a common gastrointestinal disorder with complex etiology. Clinically, it manifests as reduced bowel movement frequency, hard stools, straining during defecation, or incomplete evacuation, significantly impairing patients' qualit…
  pubmed Zhao X, Song Y, Zhu J, Ma B 等 2026 置信度 0.82
• From male PCOS to male endocrine-metabolic syndrome: a gender-neutral hypothesis.
  The proposed renaming of polycystic ovary syndrome (PCOS) as polyendocrine metabolic ovarian syndrome (PMOS) is an important step toward recognizing the systemic endocrine-metabolic nature of a condition historically misrepresented by ovarian cystic morphology…
  pubmed Nordio M, Barbaro D, Pavacci V 2026 置信度 0.82