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• Next-gen cloning and purification technologies to rapidly generate synthetic genes and proteins
  crossref Malathi Raman 2017-08-01T10:01:50Z 置信度 0.70
• Plant metabolism and synthetic biology
  crossref Zhihua Liao, Zhihua Zhou, Yanran Li, Yang Zhang 2023-08-16T21:09:33Z 置信度 0.70
• A synthetic protein-level neural network in mammalian cells
  Abstract Artificial neural networks provide a powerful paradigm for information processing that has transformed diverse fields. Within living cells, genetically encoded synthetic molecular networks could, in principle, harness principles of neural computation …
  crossref Zibo Chen, James M. Linton, Ronghui Zhu, Michael B. Elowitz 2022-07-11T20:45:19Z 置信度 0.70
• Treatment of Acute Myeloid Leukemia
  crossref Josep J Centelles 2015-01-05T11:27:45Z 置信度 0.70
• Synthetic mechanobiology
  crossref John T. Ngo 2026-04-20T15:03:25Z 置信度 0.70
• Easing the global burden of diarrhoeal disease: can synthetic biology help?
  crossref Prerna Vohra, Garry W. Blakely 2013-07-19T08:16:40Z 置信度 0.70
• Design and characterization of synthetic promoters
  crossref Boris Kirov, Slavil Peykov 2022-01-14T22:43:45Z 置信度 0.70
• Rational Design of Programmable Monodisperse Semi-Synthetic Protein Nanomaterials Containing Engineered Disulfide Functionality
  Abstract The reversible nature of disulfide functionality has been exploited to design intelligent materials such as nanocapsules, micelles, vesicles, inorganic nanoparticles, peptide and nucleic acid nanodevices. However, to our knowledge, there are no report…
  crossref Pavankumar Janardhan Bhandari, Britto S Sandanaraj 2021-02-07T23:20:14Z 置信度 0.70
• Emerging Policy Issues in Synthetic Biology
  crossref 2014-04-26T04:15:06Z 置信度 0.70
• Synthetic Condensed-Phase Signaling Expands Kinase Specificity and Responds to Macromolecular Crowding
  Abstract Liquid–liquid phase separation (LLPS) can concentrate biomolecules and accelerate reactions within membraneless organelles. For example, the nucleolus and PML-nuclear bodies are thought to create network hubs by bringing signaling molecules such as ki…
  crossref Dajun Sang, Tong Shu, Liam J. Holt 2021-12-14T11:29:28Z 置信度 0.70
• Spontaneous Emergence of Information in Simple Biological Systems
  crossref 2015-05-06T08:55:25Z 置信度 0.70
• Genomic encryption of digital data stored in synthetic DNA
  ABSTRACT Today, we can read human genomes and store digital data robustly in synthetic DNA. Here we report a strategy to intertwine these two technologies to enable the secure storage of valuable information in synthetic DNA, protected with personalized keys. …
  crossref Robert N. Grass, Reinhard Heckel, Christophe Dessimoz, Wendelin J. Stark 2019-11-08T10:24:51Z 置信度 0.70
• Capturing Full Cellular Regulation In silico using “Big” Data: A Frontier for Systems Biology Perspectives
  crossref Steven Sowa Jorge Vazquez-Anderson 2013-12-19T23:55:13Z 置信度 0.70
• A synthetic integral feedback controller for robust tunable regulation in bacteria
  Abstract We report on the first engineered integral feedback control system in a living cell. The controller is based on the recently published antithetic integral feedback motif [1] which has been analytically shown to have favorable regulation properties. It…
  crossref Gabriele Lillacci, Stephanie Aoki, David Schweingruber, Mustafa Khammash 2017-08-02T01:10:20Z 置信度 0.70
• A synthetic distributed genetic multi-bit counter
  Summary A design for genetically-encoded counters is proposed via repressor-based circuits. An N -bit counter reads sequences of input pulses and displays the total number of pulses, modulo 2 N . The design is based on distributed computation, with specialized…
  crossref Tianchi Chen, M. Ali Al-Radhawi, Christopher A. Voigt, Eduardo D. Sontag 2021-11-11T19:20:10Z 置信度 0.70
• Standardised Genetic Output Measurement
  crossref 2016-04-07T23:28:32Z 置信度 0.70
• Experimental tests of functional molecular regeneration via a standard framework for coordinating synthetic cell building
  Abstract The construction of synthetic cells from lifeless ensembles of molecules is expected to require integration of hundreds of genetically-encoded functions whose collective capacities enable self-reproduction in simple environments. To date the regenerat…
  crossref Eric Wei, Drew Endy 2021-03-05T15:13:15Z 置信度 0.70
• Vibe Coding Specificity Foundation Models
  Molecular recognition - the determination of which agent binds which target - governs adaptive immunity, gene regulation, signal transduction, RNA silencing, enzyme catalysis, and the selectivity of therapeutics. Determining binding specificity remains depende…
  crossref Sai T Reddy 2026-06-05T04:25:25Z 置信度 0.70
• Gene Discovery for Synthetic Biology
  crossref E.C. O’Neill, G. Saalbach, R.A. Field 2016-04-05T21:31:28Z 置信度 0.70
• Joint universal modular plasmids (JUMP): a flexible vector platform for synthetic biology
  Abstract Generation of new DNA constructs is an essential process in modern life science and biotechnology. Modular cloning systems based on Golden Gate cloning, using Type IIS restriction endonucleases, allow assembly of complex multipart constructs from reus…
  crossref Marcos Valenzuela-Ortega, Christopher French 2021-02-03T17:31:30Z 置信度 0.70
• Computational Proteomics
  crossref Debasree Sarkar, Sudipto Saha 2016-09-08T14:55:01Z 置信度 0.70
• Host-aware RNA-based control of synthetic microbial consortia
  Abstract Microbial consortia have been utilised for centuries to produce fermented foods and have great potential in applications such as therapeutics, biomaterials, fertilisers, and biobased production. Working together, microbes become specialized and perfor…
  crossref Alice Boo, Harman Mehta, Rodrigo Ledesma Amaro, Guy-Bart Stan 2023-05-16T01:05:18Z 置信度 0.70
• Yeast Synthetic Biology Approaches for the Production of Valuable Polyphenolic Compounds
  crossref Daniela Gomes, João Rainha, Ligia R. Rodrigues, Joana L. Rodrigues 2022-01-21T20:18:46Z 置信度 0.70
• Application of synthetic biology in age-related and neurodegenerative disease
  crossref Sourav Ghosh, Sayantan Kundu, Riya Jana, Biswajit Basu 等 2025-11-08T11:00:56Z 置信度 0.70
• Programming languages for synthetic biology
  crossref P. Umesh, F. Naveen, Chanchala Uma Maheswara Rao, Achuthsankar S. Nair 2011-02-19T00:58:59Z 置信度 0.70
• Systems and Synthetic Biology in Hydrocarbon Microbiology: Tools
  crossref Víctor de Lorenzo 2016-03-18T16:38:00Z 置信度 0.70
• Patenting Synthetic Biology: Weathering the Perfect Storm
  Synthetic biology carries with it endless promises for humankind. These Promises range from discoveries such as finding solutions to food shortage, procedures for energy production, and genetic codes that kill cancers. The emergence of synthetic biology howeve…
  crossref Michael Kalule 2015-09-09T19:01:01Z 置信度 0.70
• The Societal Impact of Synthetic Biology
  crossref Filippa Lentzos, Caitlin Cockerton, Susanna Finlay, R. Alexander Hamilton 等 2015-08-28T01:11:52Z 置信度 0.70
• Recent Advances in Synthetic Biology Applications of Pichia Species
  crossref Wan Sun, Yimeng Zuo, Zhanyi Yao, Jucan Gao 等 2022-01-21T20:18:46Z 置信度 0.70
• Synthetic Genetic Codes as the Basis of Synthetic Life
  crossref J. Tze‐Fei Wong, Hong Xue 2011-06-21T08:11:18Z 置信度 0.70
• A synthetic Notch (synNotch) system linking intratumoral immune-cancer cell communication to a synthetic blood biomarker assay
  ABSTRACT Introduction Cellular immunotherapy has greatly improved cancer treatment in recent years. For instance, chimeric antigen receptor (CAR) T-cell therapy has been proven highly effective in treating hematological malignancies, and many CAR cell designs …
  crossref YangHao Fu, TianDuo Wang, John A. Ronald 2023-09-27T00:55:17Z 置信度 0.70
• A Methodology to Annotate Systems Biology Markup Language Models with the Synthetic Biology Open Language
  crossref Nicholas Roehner, Chris J. Myers 2013-08-26T16:08:27Z 置信度 0.70
• Optimal Design of Robust Synthetic Biological Oscillators
  crossref Chia Hua Chuang Chun Liang Lin 2015-05-06T04:55:25Z 置信度 0.70
• Synthetic organisms and living machines
  crossref Anna Deplazes, Markus Huppenbauer 2009-10-08T22:50:37Z 置信度 0.70
• Computer-Aided Design of Synthetic Biological Constructs with the Synthetic Biology Software Suite
  crossref Katherine Volzing, Konstantinos Biliouris, Patrick Smadbeck, Yiannis Kaznessis 2013-09-09T16:24:22Z 置信度 0.70
• Synthetic Biology: Safety Issues
  crossref Xue Zhu, Dan Zhao, Kang Ning 2023-06-19T08:02:26Z 置信度 0.70
• The Regulation of Synthetic Biology by EU Law: Current State and Prospects
  crossref Gerd Winter 2014-09-27T04:08:50Z 置信度 0.70
• Synthetic Biology Regulatory Landscape
  crossref Abhinav Warrier, Rashi Diwan, Gayatri D. Lele, Srushti N. Tijare 等 2026-05-17T22:08:09Z 置信度 0.70
• Shuffling of DNA Cassettes in a Synthetic Integron
  crossref David Bikard, Didier Mazel 2013-08-30T20:48:21Z 置信度 0.70
• Application of cell-free system in synthetic biology
  crossref Bhupendra Gopalbhai Prajapati, Neelakanta Sarvashiva Kiran, Chandrashekar Yashaswini, Ankita Chatterjee 2025-11-08T11:00:56Z 置信度 0.70
• Synthetic Biology for the Development of Biodrugs and Designer Crops and the Emerging Governance Issues
  crossref Archana Chugh, Pooja Bhatia, Aastha Jain 2014-12-15T14:20:22Z 置信度 0.70
• Application of synthetic biology in infectious and communicable diseases
  crossref Sayantan Kundu, Shilpa Chatterjee, Biswajit Basu, Bhupendra Gopalbhai Prajapati 2025-11-08T11:00:56Z 置信度 0.70
• Synthetic Gene Regulation in Cyanobacteria
  crossref Cheryl M. Immethun, Tae Seok Moon 2018-08-08T07:12:49Z 置信度 0.70
• Applications of genome synthesis and editing in synthetic biology
  crossref Himel Mondal, Shaikat Mondal, Sairavi Kiran Biri, Shreya Sharma 2025-11-08T11:00:56Z 置信度 0.70
• Microbial synthetic biology for human therapeutics
  crossref Aastha Jain, Pooja Bhatia, Archana Chugh 2012-06-01T23:16:33Z 置信度 0.70
• Computer Aided Assembly and Verification of Synthetic Chromosomes
  crossref Giovanni Stracquadanio, Valentin Zulkower 2020-11-12T14:03:09Z 置信度 0.70
• Synthetic Biology: Diverse Layers of Live
  crossref Michael Bölker, Margret Engelhard, Nediljko Budisa 2016-04-15T09:10:13Z 置信度 0.70
• Synthetic Gene Circuit Analysis and Optimization
  crossref Irene Otero-Muras, Julio R. Banga 2020-11-12T14:03:09Z 置信度 0.70
• Synthetic Biology: Development Issues
  crossref Kang Ning, Yi Zhan, Dan Zhao 2023-06-19T08:02:26Z 置信度 0.70
• Chapter 1. Designer bases, base pairs, and genetic sets: biochemical and biological activity
  crossref Emily M. Harcourt, Eric T. Kool 2014-06-02T14:28:59Z 置信度 0.70
• Never‐Born RNAs: Versatile Modules for Chemical Synthetic Biology
  crossref Davide De Lucrezia, Fabrizio Anella, Cristiano Chiarabelli, Pier Luigi Luisi 2011-06-21T08:11:10Z 置信度 0.70
• Playing God? Synthetic biology as a theological and ethical challenge
  crossref Peter Dabrock 2009-10-08T22:50:37Z 置信度 0.70
• Modeling Subcellular Protein Recruitment Dynamics for Synthetic Biology
  crossref Kwabena A. Badu-Nkansah, Diana Sernas, Dean E. Natwick, Sean R. Collins 2022-10-13T08:04:43Z 置信度 0.70
• Designing de novo: interdisciplinary debates in synthetic biology
  crossref Ana Delgado, Manuel Porcar 2013-04-08T06:02:53Z 置信度 0.70
• Bringing it all together: Designing technologies, building worlds
  This chapter explores governance in synthetic biology through a case study of the Arsenic Biosensor Collaboration (ABC), illustrating the challenges of translating a project from lab to field. It examines how the researchers involved navigated regulatory frame…
  crossref Emma Frow, Robert Smith, Lalitha Sundaram 2026-08-04T16:44:40Z 置信度 0.70
• Synthetic Microbial Consortia and their Applications
  crossref Robert P. Smith, Yu Tanouchi, Lingchong You 2013-09-09T20:23:49Z 置信度 0.70
• Beyond directed evolution: Darwinian selection as a tool for synthetic biology
  crossref Manuel Porcar 2009-10-09T14:34:15Z 置信度 0.70
• Advances in CRISPR-Cas9 technology in synthetic biology
  crossref Swapnil Srivastava, Ritu Rani, Chetna Tyagi, Shivangi Tyagi 等 2026-05-29T12:09:26Z 置信度 0.70
• What exactly is synthetic biology?
  crossref Michael Gross 2011-08-22T23:04:42Z 置信度 0.70
• Synthetic Biology in Asia: New Kids on the Block
  crossref Matthew Wook Chang 2016-11-21T11:48:10Z 置信度 0.70
• Chapter 12. Disruptive innovation: channeling photosynthetic electron flow into light-driven synthesis of high-value products
  crossref Birger Lindberg Møller 2014-06-02T14:28:59Z 置信度 0.70
• Synthetic Genetic Codes Designed to Hinder Evolution
  ABSTRACT One challenge in engineering organisms is guaranteeing system behavior over many generations. Spontaneous mutations that arise before or during use can impact heterologous genetic functions, disrupt system integration, or change organism phenotype. He…
  crossref Jonathan Calles, Isaac Justice, Detravious Brinkley, Alexa Garcia 等 2019-07-08T16:05:12Z 置信度 0.70
• A Synthetic Defective Interfering SARS-CoV-2
  Viruses thrive by exploiting the cells they infect but must also produce viral proteins to replicate and infect other cells. As a consequence, they are also susceptible to exploitation by defective versions of themselves that do not produce such proteins. A de…
  crossref Shun Yao, Anoop Narayanan, Sydney Majowicz, Joyce Jose 等 2020-11-24T02:35:23Z 置信度 0.70
• Synthetic Biology: Case Studies
  crossref Pei Liu, Yi Zhan, Kang Ning 2023-06-19T08:02:26Z 置信度 0.70
• Identifying competition phenotypes in synthetic biochemical circuits
  Abstract Synthetic gene circuits require cellular resources, which are often limited. This leads to competition for resources by different genes, which alter a synthetic genetic circuit’s behavior. However, the manner in which competition impacts behavior depe…
  crossref M. Ali Al-Radhawi, Domitilla Del Vecchio, Eduardo D. Sontag 2022-03-24T00:10:16Z 置信度 0.70
• Design and Mathematical Analysis of Activating Amplifiers that Enable Modular Temporal Control in Synthetic Circuits
  ABSTRACT The ability to control mammalian cells such that they self-organize or enact therapeutic effects as desired has incredible implications. Not only would it further our understanding of native processes such as development and the immune response, but i…
  crossref Calvin Lam 2023-03-19T03:46:39Z 置信度 0.70
• Layered Feedback Control Overcomes Performance Trade-off in Synthetic Biomolecular Networks
  Abstract Layered feedback is an optimization strategy in feedback control designs widely used in electrical and mechanical engineering. Layered control theory suggests that the performance of controllers is bound by the universal robustness-efficiency tradeoff…
  crossref Chelsea Y. Hu, Richard M. Murray 2021-09-14T00:50:18Z 置信度 0.70
• Cell-free gene regulatory network engineering with synthetic transcription factors
  Abstract Gene regulatory networks are ubiquitous in nature and critical for bottom-up engineering of synthetic networks. Transcriptional repression is a fundamental function that can be tuned at the level of DNA, protein, and cooperative protein – protein inte…
  crossref Zoe Swank, Nadanai Laohakunakorn, Sebastian J. Maerkl 2018-09-04T14:55:18Z 置信度 0.70
• Long-distance communication in synthetic bacterial consortia through active signal propagation
  Abstract A synthetic cell-cell signaling circuit should ideally be (1) metabolically lightweight, (2) insulated from endogenous gene networks, and (3) excitable rather than oscillatory or bistable. To accomplish these three features, we propose a synchronized …
  crossref James M. Parkin, Richard M. Murray 2018-05-14T07:10:11Z 置信度 0.70
• Current Progress in Synthetic Genetic Networks
  crossref Amir Pandi, Heykel Trabelsi 2020-04-13T11:02:57Z 置信度 0.70
• Regulatable assembly of synthetic microtubule architectures using engineered MAP-IDR condensates
  Summary Microtubules filaments are assembled into higher-order structures and machines critical for cellular processes using microtubule-associated proteins (MAPs). However, the design of synthetic MAPs that direct the formation of new structures in cells is c…
  crossref Chih-Chia Chang, Scott M. Coyle 2023-03-15T01:35:13Z 置信度 0.70
• Synthetic Cells
  crossref Paola Albanese, Roberto Barbaro, Fabio Mavelli, Emiliano Altamura 2026-05-17T22:41:51Z 置信度 0.70
• Design of a genetic layered feedback controller in synthetic biological circuitry
  Abstract Feedback control is the key to achieve robust performances for many engineered systems. However, its application in biological contexts is still largely unexplored. In this work, we designed, analyzed and simulated a layered controller functioning at …
  crossref Chelsea Y. Hu, Richard M. Murray 2019-05-24T14:05:18Z 置信度 0.70
• A selectable system to evaluate synthetic gene optimization features
  Abstract Heterologous gene expression – transferring genes from a natural cell or origin to another host cell, often across species – is a fundamental technique in biological research as well as biotechnological and pharmaceutical manufacturing. Optimization o…
  crossref Brevin A. Smider, Jacob Gil, Vaughn V. Smider 2019-10-31T15:19:51Z 置信度 0.70
• 1. Life by Design
  crossref 2022-11-05T17:26:52Z 置信度 0.70
• Synthetic gene networks recapitulate dynamic signal decoding and differential gene expression
  Abstract Cells live in constantly changing environments and employ dynamic signaling pathways to transduce information about the signals they encounter. However, the mechanisms by which dynamic signals are decoded into appropriate gene expression patterns rema…
  crossref Dirk Benzinger, Serguei Ovinnikov, Mustafa Khammash 2021-01-09T11:21:39Z 置信度 0.70
• A framework for the modular and combinatorial assembly of synthetic gene circuits
  ABSTRACT Synthetic gene circuits emerge from iterative design-build-test cycles. Most commonly, the time-limiting step is the circuit construction process. Here, we present a hierarchical cloning scheme based on the widespread Gibson assembly method and make t…
  crossref Javier Santos-Moreno, Yolanda Schaerli 2019-04-19T02:55:12Z 置信度 0.70
• Recent Advances, Challenges, and Opportunities in Synthetic Genomes
  crossref Vijai Singh 2020-04-13T11:02:57Z 置信度 0.70
• Emergent properties in complex synthetic bacterial promoters
  Summary Regulation of gene expression in bacteria results from the interplay between transcriptional factors (TFs) at target promoters, and how the arrangement of binding sites determines the regulatory logic of promoters is not well known. Here, we generated …
  crossref Lummy Maria Oliveira Monteiro, Letícia Magalhães Arruda, Rafael Silva-Rocha 2017-06-21T01:10:11Z 置信度 0.70
• Design and Implementation of Synthetic Oscillators
  crossref Boris Kirov, Slavil Peykov 2026-05-18T00:28:57Z 置信度 0.70
• Development of synthetic biotics as treatment for human diseases
  Abstract Advances in synthetic biology have allowed the generation of strains of bacteria that are genetically altered to have specific therapeutic benefits. These synthetic biotics, also widely referred to as engineered living therapeutics, have tremendous po…
  crossref Aoife M Brennan 2022-01-30T21:41:45Z 置信度 0.70
• Systems and synthetic biology-aided biosynthesis pathway design
  crossref Xinrui Zhao 2020-07-24T07:18:54Z 置信度 0.70
• Genome-Scale Metabolic Modeling of Escherichia coli and Its Chassis Design for Synthetic Biology Applications
  crossref Bashir Sajo Mienda, Andreas Dräger 2020-11-12T14:03:09Z 置信度 0.70
• Design Principles of Synthetic Biological Oscillators
  crossref Ashish Panghalia, Vikram Singh 2020-04-13T11:02:57Z 置信度 0.70
• Cell-free synthetic biology: Engineering in an open world
  crossref Yuan Lu 2017-03-02T23:47:23Z 置信度 0.70
• Synthetic Networks
  crossref Gholamreza Abdi, Kirtan Dave, Unnati Panchal, Saloni Gautam 2026-05-17T22:25:32Z 置信度 0.70
• Trichome Transcripts as Efficiency Control for Synthetic Biology and Molecular Farming
  crossref Richard Becker, Christian Görner, Pavel Reichman, Nico Dissmeyer 2022-02-21T16:15:57Z 置信度 0.70
• The Societal Impact of Synthetic Biology
  crossref Filippa Lentzos, Caitlin Cockerton, Susanna Finlay, R. Alexander Hamilton 等 2019-01-21T03:10:23Z 置信度 0.70
• Getting Ready for Synthetic Biology
  crossref 2008-10-17T13:08:50Z 置信度 0.70
• Application of Yeast Synthetic Biology for the Production of Citrus Flavors
  crossref Karim Farmanpour-Kalalagh, Arman Beyraghdar Kashkooli, Alireza Babaei 2022-01-21T20:18:46Z 置信度 0.70
• The Eugene Language for Synthetic Biology
  crossref Lesia Bilitchenko, Adam Liu, Douglas Densmore 2013-01-16T16:47:51Z 置信度 0.70
• Shaping the science–industry–policy interface in synthetic biology
  crossref Sibylle Gaisser, Thomas Reiss 2009-10-08T18:50:37Z 置信度 0.70
• Computational Tools for Applying Multi-level Models to Synthetic Biology
  crossref Roberta Bardini, Gianfranco Politano, Alfredo Benso, Stefano Di Carlo 2018-10-01T16:24:30Z 置信度 0.70
• Synthetic Dyes in Biology, Medicine and Chemistry
  crossref 2016-08-03T22:50:17Z 置信度 0.70
• RNA Synthetic Biology
  crossref Vijai Singh 2026-02-07T04:06:10Z 置信度 0.70
• The art of trans-boundary governance: the case of synthetic biology
  crossref Joy Y. Zhang 2012-08-27T11:28:13Z 置信度 0.70
• New Genetic Codes
  crossref 2016-04-07T23:28:32Z 置信度 0.70
• BRCA1, PARP, and 53BP1: conditional synthetic lethality and synthetic viability
  crossref A. Aly, S. Ganesan 2011-01-30T22:17:53Z 置信度 0.70
• Professionalization as a governance strategy for synthetic biology
  crossref Lorna Weir, Michael J. Selgelid 2009-10-08T18:50:37Z 置信度 0.70
• New Frontiers and Applications of Synthetic Biology
  crossref 2022-01-14T18:02:35Z 置信度 0.70