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• Study: AI7KE+ – A non-limited Artificial Intelligence as a system compatible with Natural Intelligence (NI) from an evolutionary ethics perspective
  A world model of Holistic Information Theory (GIT) with i = E, Dimension 0, Super-nothing and the seven languages of the laws of nature – with interdisciplinary follow-up studies (Physics · Medicine · Genetics · Biology · Sociology) Author: Dieter LiedtkeYear:…
  datacite Dieter Liedtke 2026 置信度 0.66
• Study: AI7KE+ – A non-limited Artificial Intelligence as a system compatible with Natural Intelligence (NI) from an evolutionary ethics perspective
  A world model of Holistic Information Theory (GIT) with i = E, Dimension 0, Super-nothing and the seven languages of the laws of nature – with interdisciplinary follow-up studies (Physics · Medicine · Genetics · Biology · Sociology) Author: Dieter LiedtkeYear:…
  datacite Liedtke, Dieter Walter 2026 置信度 0.66
• Study: AI7KE+ – A non-limited Artificial Intelligence as a system compatible with Natural Intelligence (NI) from an evolutionary ethics perspective
  A world model of Holistic Information Theory (GIT) with i = E, Dimension 0, Super-nothing and the seven languages of the laws of nature – with interdisciplinary follow-up studies (Physics · Medicine · Genetics · Biology · Sociology) Author: Dieter LiedtkeYear:…
  datacite Liedtke, Dieter Walter 2026 置信度 0.66
• Active Vitalism Paradigm
  Abstract Current models for long-duration interstellar transit and planetary colonization remain constrained by the "Chariot Paradigm"—a reliance on static structural integrity and continuous external management. This paper introduces the Active Vitalism Parad…
  datacite Kasiulevicius, Egidijus, Kasiulevicius, Azuolas, Kasiuleviciute, Saule, Kasiuleviciene, Ausra 2026 置信度 0.66
• Active Vitalism Paradigm
  Abstract Current models for long-duration interstellar transit and planetary colonization remain constrained by the "Chariot Paradigm"—a reliance on static structural integrity and continuous external management. This paper introduces the Active Vitalism Parad…
  datacite Kasiulevicius, Egidijus, Kasiulevicius, Azuolas, Kasiuleviciute, Saule, Kasiuleviciene, Ausra 2026 置信度 0.66
• paralogSL: Paralog-Based Synthetic Lethality Prioritization via Delta Dependency
  A lightweight R package for prioritizing paralog-based synthetic lethality (SL) candidates through Delta Dependency analysis. Computes DD scores from DepMap Chronos gene-effect data, identifies candidate paralog-SL pairs using HGNC gene family annotations, and…
  datacite Mo, Qingqing, Zhu, Tao 2026 置信度 0.66 synthetic lethalityparalog compensationcancer dependency mapdrug target discoverycomputational biology
• Optimizing RNA yield using deep neural networks coupled to massively parallel screening
  Messenger RNA (mRNA)-based therapeutics have emerged as a powerful platform for vaccines, protein replacement therapies, and cancer immunotherapy. A critical bottleneck in mRNA development is manufacturing large quantities of RNA economically, as measured by R…
  datacite Zheng, Dinghai, Hong, Justin, Wang, Jun, Villain, Adrien 等 2026 置信度 0.66 Genomics (q-bio.GN)Biomolecules (q-bio.BM)FOS: Biological sciences
• paralogSL: Paralog-Based Synthetic Lethality Prioritization via Delta Dependency
  A lightweight R package for prioritizing paralog-based synthetic lethality (SL) candidates through Delta Dependency analysis. Computes DD scores from DepMap Chronos gene-effect data, identifies candidate paralog-SL pairs using HGNC gene family annotations, and…
  datacite Mo, Qingqing, Zhu, Tao 2026 置信度 0.66 synthetic lethalityparalog compensationcancer dependency mapdrug target discoverycomputational biology
• paralogSL: Paralog-Based Synthetic Lethality Prioritization via Delta Dependency
  A lightweight R package for prioritizing paralog-based synthetic lethality (SL) candidates through Delta Dependency analysis. Computes DD scores from DepMap Chronos gene-effect data, identifies candidate paralog-SL pairs using HGNC gene family annotations, and…
  datacite Mo, Qingqing, Zhu, Tao 2026 置信度 0.66 synthetic lethalityparalog compensationcancer dependency mapdrug target discoverycomputational biology
• Engineered bacterial therapeutics from synthetic biology to clinical translation: A multi-database scientometric analysis, 2000–2026
  Engineered bacterial therapeutics integrate programmable strain engineering with biomedical functions such as sensing, delivery, immune modulation, microbiome intervention, and disease management. This study conducted a multi-database bibliometric analysis to …
  datacite Hanyu Zhou, Jiaqi He, Jiabin Chen, Shuyu Ge 等 2026 置信度 0.66 Space ScienceMicrobiologyBiotechnologyInformation Systems not elsewhere classifiedScience Policy
• Engineered bacterial therapeutics from synthetic biology to clinical translation: A multi-database scientometric analysis, 2000–2026
  Engineered bacterial therapeutics integrate programmable strain engineering with biomedical functions such as sensing, delivery, immune modulation, microbiome intervention, and disease management. This study conducted a multi-database bibliometric analysis to …
  datacite Hanyu Zhou, Jiaqi He, Jiabin Chen, Shuyu Ge 等 2026 置信度 0.66 Space ScienceMicrobiologyBiotechnologyInformation Systems not elsewhere classifiedScience Policy
• ARTICLE XI: The Avicenna Protocol The Speciation Horizon: Cyber-Biological Ectothermy, Macroscopic Quantum Coherence, and the Emergence of Homo Synchronis
  Orthodox evolutionary biology and clinical medicine operate under the assumption that human development is a slow, random accumulation of mutations, treating dynamic cyber-biological threats with primitive, static pharmacology. Consequently, the human macro-or…
  datacite shariatpanahi, Seyed Mahyar 2026 置信度 0.66 Trans-Disciplinary Axiomatic Synthesis; Cyber-Biological Ectothermy; Nano-Twin Protectorate; Quantum Biology; Speciation Horizon; Macroscopic Quantum Coherence; Informational Thermodynamics; Homo Synchronis.
• ARTICLE XI: The Avicenna Protocol The Speciation Horizon: Cyber-Biological Ectothermy, Macroscopic Quantum Coherence, and the Emergence of Homo Synchronis
  Orthodox evolutionary biology and clinical medicine operate under the assumption that human development is a slow, random accumulation of mutations, treating dynamic cyber-biological threats with primitive, static pharmacology. Consequently, the human macro-or…
  datacite shariatpanahi, Seyed Mahyar 2026 置信度 0.66 Trans-Disciplinary Axiomatic Synthesis; Cyber-Biological Ectothermy; Nano-Twin Protectorate; Quantum Biology; Speciation Horizon; Macroscopic Quantum Coherence; Informational Thermodynamics; Homo Synchronis.
• Introduction to Biology: A Generative Approach
  Introduction to Biology: A Generative Approach is an open biology textbook with forty-four chapters, ranging from systems science and chemical foundations through cells, metabolism, genetics, microbiology, physiology, evolution, and ecology. Organized as Unit …
  datacite Friedman, Daniel Ari 2026 置信度 0.66 BiologyBiologyReproductive biologyDevelopmental biologyStructural biology
• Introduction to Biology: A Generative Approach
  Introduction to Biology: A Generative Approach is an open biology textbook with forty-four chapters, ranging from systems science and chemical foundations through cells, metabolism, genetics, microbiology, physiology, evolution, and ecology. Organized as Unit …
  datacite Friedman, Daniel Ari 2026 置信度 0.66 BiologyBiologyReproductive biologyDevelopmental biologyStructural biology
• Detection of Governance Transitions in High-Dimensional Systems via Constraint Emergence Metrics
  This work introduces a general framework for detecting regime transitions in high-dimensional systems using a scalar metric termed the Constraint Score. The method combines three components derived from sliding-window principal component analysis: information …
  datacite Morris, Jamie 2026 置信度 0.66
• Detection of Governance Transitions in High-Dimensional Systems via Constraint Emergence Metrics
  This work introduces a general framework for detecting regime transitions in high-dimensional systems using a scalar metric termed the Constraint Score. The method combines three components derived from sliding-window principal component analysis: information …
  datacite Morris, Jamie 2026 置信度 0.66
• Data and code associated with the publication: Reaction enhancement via product scavenging and phase separation-driven pathway canalization
  Simulation codes and raw data (gel images and microscope images) for the paper entitled “Reaction enhancement via product scavenging and phase separation-driven pathway canalization”. The repository serves researchers, primarily in the field of phase separatio…
  datacite Kang, Byunghwa, Lee, Heonjoon, Kengmana, Eli, Yea, Jie Yi 等 2026 置信度 0.66 ChemistryMedicine, Health and Life SciencesribozymeDNAzymescavenger
• A Universal Complexity Functional: A Cross-Domain, Measurable Definition of Natural Complexity
  General Evolution Principle; Universal Condensation Principle
  datacite Aleksandrov, Atanas Georgiev 2026 置信度 0.66 General Evolution PrincipleUniversal Condensation Principleuniversal complexitycomplexity functionalcondensed degrees of freedom
• A Universal Complexity Functional: A Cross-Domain, Measurable Definition of Natural Complexity
  General Evolution Principle; Universal Condensation Principle
  datacite Aleksandrov, Atanas Georgiev 2026 置信度 0.66 General Evolution PrincipleUniversal Condensation Principleuniversal complexitycomplexity functionalcondensed degrees of freedom
• Aero Shadow
  Yes. The Aero Shadow is meaningfully better than a stock Storm Shadow in every performance category. StructuralThe stock Storm Shadow uses a conventional metal airframe at 1,300 kg. The Aero Shadow replaces it with a skeletonized carbon-flex fuselage, cutting …
  datacite lee, francis 2026 置信度 0.66
• Aero Shadow
  The Revised Real-World Spec Sheet Feature Fictional Version Real-World Engineering Solution Power Source 12 V / 10 Ah Battery Engine-Driven High-Output Alternator Stealth Ionized Plasma Shroud DRFM Electronic Jamming + Radar Absorbent Skin Propulsion Pneumatic…
  datacite lee, francis 2026 置信度 0.66
• Aero Shadow
  Yes. The Aero Shadow is meaningfully better than a stock Storm Shadow in every performance category. StructuralThe stock Storm Shadow uses a conventional metal airframe at 1,300 kg. The Aero Shadow replaces it with a skeletonized carbon-flex fuselage, cutting …
  datacite lee, francis 2026 置信度 0.66
• Aero Shadow
  Yes. The Aero Shadow is meaningfully better than a stock Storm Shadow in every performance category. StructuralThe stock Storm Shadow uses a conventional metal airframe at 1,300 kg. The Aero Shadow replaces it with a skeletonized carbon-flex fuselage, cutting …
  datacite lee, francis 2026 置信度 0.66
• Aero Shadow
  Based on the document, the Dark Wind Heavy hypersonic upgrade outperforms existing missiles like Russia's 3M22 Zircon by utilizing a Laser-Induced Directed Energy Air Spike (DEAS) to bypass the standard atmospheric drag and thermal limits that restrict current…
  datacite lee, francis 2026 置信度 0.66
• Aero Shadow
  Yes. The Aero Shadow is meaningfully better than a stock Storm Shadow in every performance category. StructuralThe stock Storm Shadow uses a conventional metal airframe at 1,300 kg. The Aero Shadow replaces it with a skeletonized carbon-flex fuselage, cutting …
  datacite lee, francis 2026 置信度 0.66
• Aero Shadow
  The Revised Real-World Spec Sheet now both missile work Feature Fictional Version Real-World Engineering Solution Power Source 12 V / 10 Ah Battery Engine-Driven High-Output Alternator Stealth Ionized Plasma Shroud DRFM Electronic Jamming + Radar Absorbent Ski…
  datacite lee, francis 2026 置信度 0.66
• Multiplexed Acoustic-Optic Epigenetics: Biological Rhythm Synchronization and the Phase-Locked Encoding of Constraint Topology
  Abstract Current models of epigenetics and chronobiology acknowledge the importance of temporal synchronization but lack a unified physical mechanism for how macroscopic biological rhythms (e.g., circadian, cardiac, respiratory) encode high-dimensional environ…
  datacite Nickolas Patrick Joseph Schoff 2026 置信度 0.66 BiologyBiologyDevelopmental biologyStructural biologyMolecular biology
• Physical Learning in Engineered Bacteria through Autonomous Weight Updates
  Training physical neural networks (PNNs) directly in their substrate, without external algorithms, remains a central challenge for neuromorphic computing and synthetic biology. Synthetic gene circuits can implement logic gates and even neural network architect…
  datacite Jaramillo, Alfonso 2026 置信度 0.66 physical learningneuromorphic computingSynthetic Biology
• Physical Learning in Engineered Bacteria through Autonomous Weight Updates
  Training physical neural networks (PNNs) directly in their substrate, without external algorithms, remains a central challenge for neuromorphic computing and synthetic biology. Synthetic gene circuits can implement logic gates and even neural network architect…
  datacite Jaramillo, Alfonso 2026 置信度 0.66 physical learningneuromorphic computingSynthetic Biology
• Enzyme Kinetics and Molecular Motors. Biological Phase Engineering. Applications with GRTOE
  The EBio series — Biological Phase Engineering, see under Related works at the end of this page the ordered links to the continuation articles, the simulation articles with real data, and Volume 7 of the conceptual revision, proposes and develops a biophysical…
  datacite Jonatan P. Camargo 2025 置信度 0.66 BiologyBiology/standardsBiology/methods
• Enzyme Kinetics and Molecular Motors. Biological Phase Engineering. Applications with GRTOE
  The EBio series — Biological Phase Engineering, see under Related works at the end of this page the ordered links to the continuation articles, the simulation articles with real data, and Volume 7 of the conceptual revision, proposes and develops a biophysical…
  datacite Jonatan P. Camargo 2025 置信度 0.66 BiologyBiology/standardsBiology/methods
• Information Field Density as a Testable Cross-Scale Organizing Quantity for Chemical and Biological Order
  Living systems are usually described by separate theories for bonding, energy flow, replication, repair, selection and failure. I propose information field density, denoted rho_I, as an operational cross-scale organizing quantity whose basal carrier is connect…
  datacite ARIKAN, FURKAN 2026 置信度 0.66 information field density molecular geometry biological organization origin of life synthetic cells systems biology chirality aging disease biological phase transition
• Information Field Density as a Testable Cross-Scale Organizing Quantity for Chemical and Biological Order
  Living systems are usually described by separate theories for bonding, energy flow, replication, repair, selection and failure. I propose information field density, denoted rho_I, as an operational cross-scale organizing quantity whose basal carrier is connect…
  datacite ARIKAN, FURKAN 2026 置信度 0.66 information field density molecular geometry biological organization origin of life synthetic cells systems biology chirality aging disease biological phase transition
• Designing Microporous Annealed Particle (MAP) Scaffolds with Stable, Functional Porosity for Cell Integration in Challenging Clinical Applications
  Regenerative engineering combines stem cell therapies with materials science and developmental biology for clinical translation to regenerate complex tissues and organ systems and restore function. Biomaterials are integral to regenerative engineering therapie…
  datacite Flanagan, Clare 2026 置信度 0.66 regenerative engineeringbiomaterialshydrogels
• A Constructibility Theorem for Protein-Only Turing-Complete Computation: Sequential-Head Reduction via NAND-Cooperative Networks and Protein-Templated Memory Primitives
  We construct a formal computational model — the Protein Computational Substrate (PCS) — whose primitives are restricted to protein-mediated operations on a passive DNA medium. We prove two principal results: (i) any PCS satisfying five explicit axioms (NAND un…
  datacite Jang, Eunjoon 2026 置信度 0.66 Turing-completenessconstructibilityprotein computationNAND networkssequential head
• A Constructibility Theorem for Protein-Only Turing-Complete Computation: Sequential-Head Reduction via NAND-Cooperative Networks and Protein-Templated Memory Primitives
  We construct a formal computational model — the Protein Computational Substrate (PCS) — whose primitives are restricted to protein-mediated operations on a passive DNA medium. We prove two principal results: (i) any PCS satisfying five explicit axioms (NAND un…
  datacite Jang, Eunjoon 2026 置信度 0.66 Turing-completenessconstructibilityprotein computationNAND networkssequential head
• Basis-Free Pattern Architecture: Public Papers, Formal Converters, and Computational Appendices
  The following are follow-up papers based on the formulas from [The Artificial Hypothesis (AH) Subsumes the Riemann Hypothesis (RH): A Grand Closure via Emergent Brane Dynamics and Phase Stagnation Signatures] **The progress of the related patent is as follows:…
  datacite kim, minsu 2026 置信度 0.66 transformer interpretabilityrepresentation geometryintrinsic dimensionalityphase stagnationlarge language models
• Basis-Free Pattern Architecture: Public Papers, Formal Converters, and Computational Appendices
  The following are follow-up papers based on the formulas from [The Artificial Hypothesis (AH) Subsumes the Riemann Hypothesis (RH): A Grand Closure via Emergent Brane Dynamics and Phase Stagnation Signatures] **The progress of the related patent is as follows:…
  datacite kim, minsu 2026 置信度 0.66 transformer interpretabilityrepresentation geometryintrinsic dimensionalityphase stagnationlarge language models
• Data from: Why architecture matters: Controlling gene expression through design
  This dataset contains the experimental measurements and derived quantitative summaries underlying the data figures and promoter-characterization table in the manuscript “Why Architecture Matters: Controlling Gene Expression Through Design.” The primary data fi…
  datacite Lewis, Mitchell, Gupta, Abhilasha 2026 置信度 0.66 FOS: Biological sciencesFOS: Health sciencesFOS: Chemical sciencesGene regulationGene regulatory networks
• A Synthetic Biology Approach to The Production of Polyhydroxyalkanoates
  datacite All Sciences Academy 2026 置信度 0.66
• A Synthetic Biology Approach to The Production of Polyhydroxyalkanoates
  datacite All Sciences Academy 2026 置信度 0.66
• The Universal Framework of Recursive Emergence
  Introduction: The Universal Framework of Recursive Emergence The complexity of reality, from the assembly of genetic sequences to the evolution of spacetime, is not an arbitrary phenomenon. At its foundation lies a universal framework—a recursive and self-sust…
  datacite kulik, Dean Kulik 2025 置信度 0.66
• The Universal Framework of Recursive Emergence
  Introduction: The Universal Framework of Recursive Emergence The complexity of reality, from the assembly of genetic sequences to the evolution of spacetime, is not an arbitrary phenomenon. At its foundation lies a universal framework—a recursive and self-sust…
  datacite kulik, Dean Kulik 2025 置信度 0.66
• 和学《圆⊙满》生命起源统一闭环理论——基因因子(病毒)的必然性、唯一性与科学验证|周红军(笔名:红君)
  本文为周红军(笔名红君)和学《圆⊙满》体系下的研究论文:《生命起源统一闭环理论 —— 基因因子(病毒)的必然性、唯一性与科学验证》。针对 RNA 世界假说、蛋白质优先假说、代谢优先假说等现有生命起源假说存在假设过多、逻辑链条断裂、缺少唯一过渡中间态、可证伪性不足等局限,本文提出基因因子理论,将基因因子定义为蛋白质外壳结合可复制核酸片段的类病毒结构化单元,论证其是非生命物质过渡到细胞生命的唯一必经中间态。本理论满足九大科学评判标准,依托病毒学、基因组学、分子生物学、演化生物学、古生物学、医学、合成生物学多维度证据,统…
  datacite Zhou, Hongjun 2026 置信度 0.66
• 和学《圆⊙满》生命起源统一闭环理论——基因因子(病毒)的必然性、唯一性与科学验证|周红军(笔名:红君)
  本文为周红军(笔名红君)和学《圆⊙满》体系下的研究论文:《生命起源统一闭环理论 —— 基因因子(病毒)的必然性、唯一性与科学验证》。针对 RNA 世界假说、蛋白质优先假说、代谢优先假说等现有生命起源假说存在假设过多、逻辑链条断裂、缺少唯一过渡中间态、可证伪性不足等局限,本文提出基因因子理论,将基因因子定义为蛋白质外壳结合可复制核酸片段的类病毒结构化单元,论证其是非生命物质过渡到细胞生命的唯一必经中间态。本理论满足九大科学评判标准,依托病毒学、基因组学、分子生物学、演化生物学、古生物学、医学、合成生物学多维度证据,统…
  datacite Zhou, Hongjun 2026 置信度 0.66
• Engineered Bioremediation through Extremophilic Fungi
  This comprehensive report presents a complete technical specification for the development, deployment, andlong-term monitoring of Strain Matrix E-990, a genetically engineered hybrid extremophilic fungal straincombining Pleurotus ostreatus with Geomyces pannor…
  datacite Jensen, Dr. Brent Allen 2026 置信度 0.66 bioremediationextremophilic fungisynthetic biologymycoremediationPleurotus ostreatus
• Engineered Bioremediation through Extremophilic Fungi
  This comprehensive report presents a complete technical specification for the development, deployment, andlong-term monitoring of Strain Matrix E-990, a genetically engineered hybrid extremophilic fungal straincombining Pleurotus ostreatus with Geomyces pannor…
  datacite Jensen, Dr. Brent Allen 2026 置信度 0.66 bioremediationextremophilic fungisynthetic biologymycoremediationPleurotus ostreatus
• Gene Meta-Operational Mathematics: From Iteration of Genetic Operations to Operations on Operations
  This work systematically extends the full apparatus of meta-operational mathematics to the domain of genetic operations, establishing a new discipline: Gene Meta-Operational Mathematics. We define a hierarchical framework: Level 0 (elements of a base space of …
  datacite liu, shifa 2026 置信度 0.66 gene meta-operations, bornological convergence, operad, Hopf operad, non- commutative geometry, path integral, collapse dynamics, categorical duality, superdo- mains, synthetic biology.
• Gene Meta-Operational Mathematics: From Iteration of Genetic Operations to Operations on Operations
  This work systematically extends the full apparatus of meta-operational mathematics to the domain of genetic operations, establishing a new discipline: Gene Meta-Operational Mathematics. We define a hierarchical framework: Level 0 (elements of a base space of …
  datacite liu, shifa 2026 置信度 0.66 gene meta-operations, bornological convergence, operad, Hopf operad, non- commutative geometry, path integral, collapse dynamics, categorical duality, superdo- mains, synthetic biology.
• ICU, CC, and CAI values of the wild-type, vaccine, and vaccine candidate sequences derived from the Human Protein Atlas, KAZUSA, and CoCoPUTs datasets from A multi-objective sequence engineering framework for rational genetic vaccine design
  Supplementary_Tables_S4.xlsx
  datacite Je Hun Moon, Seo-Young Park, Kok Siong Ang, Yoon Ki Kim 等 2026 置信度 0.66 Synthetic biology
• ICU, CC, and CAI values of the wild-type, vaccine, and vaccine candidate sequences derived from the Human Protein Atlas, KAZUSA, and CoCoPUTs datasets from A multi-objective sequence engineering framework for rational genetic vaccine design
  Supplementary_Tables_S4.xlsx
  datacite Je Hun Moon, Seo-Young Park, Kok Siong Ang, Yoon Ki Kim 等 2026 置信度 0.66 Synthetic biology
• Supplementary material from "A multi-objective sequence engineering framework for rational genetic vaccine design"
  Genetic vaccine performance is determined not only by the delivery platforms and antigen choice but also by the coding sequence that influences antigen expression, innate immune sensing, transcript stability and sequence-associated risks. However, the design p…
  datacite Je Hun Moon, Seo-Young Park, Kok Siong Ang, Yoon Ki Kim 等 2026 置信度 0.66 Synthetic biology
• Intelligent Design of 14-3-3 Docking Proteins Utilizing Synthetic Evolution Artificial Intelligence (SYN-AI)
  The ability to write DNA code from scratch will allow for the discovery of new and interesting chemistries as well as allowing the rewiring of cell signal pathways. Herein, we have utilized synthetic evolution artificial intelligence (SYN-AI) to intelligently …
  crossref Leroy K. Davis 2019-03-24T00:15:13Z 置信度 0.70
• Tools for engineering coordinated system behaviour in synthetic microbial consortia
  Abstract Advancing synthetic biology to the multicellular level requires the development of multiple orthogonal cell-to-cell communication channels to propagate information with minimal signal interference. The development of quorum sensing devices, the corner…
  crossref Nicolas Kylilis, Guy-Bart Stan, Karen M Polizzi 2017-12-12T01:10:19Z 置信度 0.70
• The Synthetic Biology Open Language
  crossref Chris Myers, Kevin Clancy, Goksel Misirli, Ernst Oberortner 等 2014-12-08T14:39:11Z 置信度 0.70
• Synthetic Biology
  crossref 2018-05-12T09:12:31Z 置信度 0.70
• Modelling Methodologies for Systems Biology
  crossref Vikram Singh 2014-12-15T14:20:22Z 置信度 0.70
• Synthetic Circuits for the Detection of Bacteria
  crossref Monisa Anwer, Ajay Kumar 2026-05-17T22:16:55Z 置信度 0.70
• Three overlooked key functional classes for building up minimal synthetic cells
  Abstract Assembly of minimal genomes revealed many genes encoding unknown functions. Three overlooked functional categories account for some of them. Cells are prone to make errors and age. As a first key function, discrimination between proper and changed ent…
  crossref Antoine Danchin 2021-04-21T16:43:19Z 置信度 0.70
• Synthetic mammalian pattern formation driven by differential diffusivity of Nodal and Lefty
  Abstract Pattern formation is fundamental for embryonic development. Although synthetic biologists have created several patterns, a synthetic mammalian reaction-diffusion pattern has yet to be realized. TGF-β family proteins Nodal and Lefty have been proposed …
  crossref Ryoji Sekine, Tatsuo Shibata, Miki Ebisuya 2018-07-20T15:40:02Z 置信度 0.70
• Crosstalk between diverse synthetic protein degradation tags in <i>Escherichia coli</i>
  Abstract Recently, a synthetic circuit in E. coli demonstrated that two proteins engineered with LAA tags targeted to the native protease ClpXP are susceptible to crosstalk due to competition for degradation between proteins. To understand proteolytic crosstal…
  crossref Nicholas C. Butzin, William H. Mather 2017-05-13T01:10:14Z 置信度 0.70
• Light-activated assembly of connexon nanopores in synthetic cells
  Abstract During developmental processes and wound healing, activation of living cells occurs with spatiotemporal precision and leads to rapid release of soluble molecular signals, allowing communication and coordination between neighbors. Non-living systems ca…
  crossref Ahmed Sihorwala, Alexander Lin, Jeanne C. Stachowiak, Brian Belardi 2022-12-16T22:10:13Z 置信度 0.70
• Synthetic lipid-containing scaffolds enhance production by co-localizing enzymes
  Abstract Subcellular organization is critical for isolating, concentrating, and protecting biological activities. Natural subcellular organization is often achieved using co-localization of proteins on scaffold molecules, thereby enhancing metabolic fluxes and…
  crossref Cameron Myhrvold, Jessica K. Polka, Pamela A. Silver 2016-05-07T10:09:25Z 置信度 0.70
• Design of a Synthetic sRNA-based Feedback Filter Module
  Summary Filters are widely used in engineering to reduce noise and/or the magnitude of a signal of interest. Feedback filters, or adaptive filters, are preferred if the signal noise distribution is unknown. One of the main challenges in Synthetic Biology remai…
  crossref Nicolas Delalez, Aivar Sootla, George H. Wadhams, Antonis Papachristodoulou 2018-12-22T00:15:14Z 置信度 0.70
• Synthetic pluripotent bacterial stem cells
  Abstract A defining property of stem cells is their ability to differentiate via asymmetric cell division, in which a stem cell creates a differentiated daughter cell but retains its own phenotype. Here, we describe a synthetic genetic circuit for controlling …
  crossref Sara Molinari, David L. Shis, James Chappell, Oleg A. Igoshin 等 2018-10-08T10:04:52Z 置信度 0.70
• Use of synthetic proteins and future trends: The example of calstabin
  crossref Jean A Boutin 2016-09-21T13:11:14Z 置信度 0.70
• Synthetic Biology Meets Machine Learning
  crossref Brendan Fu-Long Sieow, Ryan De Sotto, Zhi Ren Darren Seet, In Young Hwang 等 2022-10-13T08:04:43Z 置信度 0.70
• Synthetic Phage for the Detection of Bacteria
  crossref Anuj Yadav, Ajay Kumar 2026-05-17T22:44:18Z 置信度 0.70
• Directed evolution of synthetic coexistence: a new path towards ecosystem design?
  crossref Sonja Billerbeck 2020-11-25T01:34:54Z 置信度 0.70
• Enzyme Systems and Their Logic
  crossref Jacques Ricard 2015-01-05T06:27:45Z 置信度 0.70
• Analysis of plant enzymes as consumable parts for synthetic biology
  crossref Nathan Tivendale 2020-09-30T08:58:12Z 置信度 0.70
• Synthetic Circuits for the Detection of Viruses
  crossref Dharmisha Solanki, Vijai Singh 2026-05-17T22:40:07Z 置信度 0.70
• Introduction
  crossref Pengcheng Fu 2009-09-22T20:46:30Z 置信度 0.70
• Engineering cellular communication between light-activated synthetic cells and bacteria
  Abstract Gene-expressing compartments assembled from simple, modular parts, are a versatile platform for creating minimal synthetic cells. In a manner synonymous with natural cells, these life-like assemblies utilise information encoded in DNA within the compa…
  crossref Jefferson M. Smith, Denis Hartmann, Michael J. Booth 2022-07-23T01:55:12Z 置信度 0.70
• Applications of Engineered Synthetic Ecosystems
  crossref Harris H. Wang, Michael T. Mee, George M. Church 2013-09-09T16:22:49Z 置信度 0.70
• Synthetic multistability in mammalian cells
  Abstract In multicellular organisms, gene regulatory circuits generate thousands of molecularly distinct, mitotically heritable states, through the property of multistability. Designing synthetic multistable circuits would provide insight into natural cell fat…
  crossref Ronghui Zhu, Jesus M. del Rio-Salgado, Jordi Garcia-Ojalvo, Michael B. Elowitz 2021-02-11T13:55:41Z 置信度 0.70
• iGEM: The Competition on Synthetic Biology
  crossref Yi Zhan, Kang Ning, Dan Zhao 2023-06-19T08:02:26Z 置信度 0.70
• Yeast synthetic minimal biosensors for evaluating protein production
  Abstract The unfolded protein response (UPR) is a highly conserved cellular response in eukaryotic cells to counteract endoplasmic reticulum (ER) stress, typically triggered by unfolded protein accumulation. In addition to its relevance to human diseases like …
  crossref Kai Peng, Heinrich Koukamp, Isak S. Pretorius, Ian T. Paulsen 2020-11-04T19:00:14Z 置信度 0.70
• From noise to synthetic nucleoli: can synthetic biology achieve new insights?
  crossref Marta Ciechonska, Alice Grob, Mark Isalan 2016-01-04T12:00:17Z 置信度 0.70
• The development of synthetic biology: a patent analysis
  crossref Davy van Doren, Stefan Koenigstein, Thomas Reiss 2013-08-21T07:12:24Z 置信度 0.70
• Modular Design of Synthetic Gene Circuits with Biological Parts and Pools
  Synthetic gene circuits can be designed in an electronic fashion by displaying their basic components-Standard Biological Parts and Pools of molecules-on the computer screen and connecting them with hypothetical wires. This procedure, achieved by our add-on fo…
  crossref Mario Andrea Marchisio 2014-12-08T14:39:11Z 置信度 0.70
• Synthetic biology: lessons from the history of synthetic organic chemistry
  crossref Brian J Yeh, Wendell A Lim 2007-08-20T20:59:11Z 置信度 0.70
• Teaching Mammalian Cells to Make New, Useful Things
  This chapter clarifies why some medicines and compounds are produced in mammalian cells rather than in bacteria or yeasts. It provides examples of biologics that can be produced in mammalian cells and lists challenges associated with producing them that are un…
  crossref Jamie Billington, Anna Mastela, Susan J. Rosser 2023-09-15T07:31:45Z 置信度 0.70
• The Sixth International Meeting on Synthetic Biology (SB6.0) Special Issue Editorial
  crossref Yizhi Cai, Tom Ellis 2014-03-21T04:04:26Z 置信度 0.70
• 4th International Conference on Biomolecular Engineering Tackles New Challenges with Synthetic Biology
  crossref Kevin V. Solomon 2013-02-15T05:01:56Z 置信度 0.70
• Rational Metabolic Pathway Prediction and Design: Computational Tools and Their Applications for Yeast Systems and Synthetic Biology
  crossref Pedro A. Saa 2022-01-21T20:18:46Z 置信度 0.70
• Synthetic biology gains momentum in Europe
  crossref David Gilbert, Alfonso Jaramillo, Natalio Krasnogor, Victor de Lorenzo 2010-10-04T08:57:14Z 置信度 0.70
• Aspects of the political economy of development and synthetic biology
  crossref Rachel Wellhausen, Gautam Mukunda 2009-10-08T22:50:37Z 置信度 0.70
• Standardization in Synthetic Biology
  crossref Kristian M. Müller, Katja M. Arndt 2011-11-15T07:12:30Z 置信度 0.70
• Modeling Challenges in the Synthetic Biology of Secondary Metabolism
  crossref Rainer Breitling, Fiona Achcar, Eriko Takano 2013-05-09T15:45:49Z 置信度 0.70
• Infrastructure: An often invisible but critical part of governance
  This chapter examines how infrastructure plays a fundamental role in shaping science, technology, and daily practice in the evolving field of synthetic biology. It explains how well-functioning infrastructure often enables progress by operating in the backgrou…
  crossref Emma Frow, Robert Smith, Lalitha Sundaram 2026-08-04T16:44:41Z 置信度 0.70
• Synthetic biology, engineering biology, market expectation
  ‘Engineering biology’ is being increasingly adopted as a term by organisations that seek to deliver benefits from ‘synthetic biology’. However, are ‘engineering biology’ and ‘synthetic biology’ different words with the same meaning or do they signal important …
  crossref Lionel Clarke 2020-12-03T21:10:56Z 置信度 0.70
• Synthetic Biology: Modulating the MAP Kinase Module
  crossref Lee Bardwell 2011-04-13T07:48:17Z 置信度 0.70
• Application of xenonucleotide in synthetic biology
  crossref Rajdip Goswami, Sourin Saha, Asim Halder, Nilanjan Sarkar 等 2025-11-08T11:00:56Z 置信度 0.70
• Application of synthetic biology in lifestyle diseases
  crossref Piyali Khamkat, Bramhajit Chatterjee, Vivek Barik, Swarupananda Mukherjee 等 2025-11-08T11:00:56Z 置信度 0.70
• Synthetic Biology: Data Resources, Web Services, and Visualizations
  crossref Yuzhu Zhang, Yi Zhan 2023-06-19T08:02:26Z 置信度 0.70
• From systems biology to synthetic biology
  crossref George M Church 2005-03-29T09:57:42Z 置信度 0.70
• Design of synthetic epigenetic circuits exhibiting positive feedback, memory effects and reversible switching
  crossref Albert Jeltsch 2017-08-01T10:01:50Z 置信度 0.70
• Synthetic Life with Alternative Nucleic Acids as Genetic Materials
  DNA, the fundamental genetic polymer of all living organisms on Earth, can be chemically modified to embrace novel functions that do not exist in nature. The key chemical and structural parameters for genetic information storage, heredity, and evolution have b…
  crossref Peng Nie, Yanfen Bai, Hui Mei 2020-08-03T07:45:57Z 置信度 0.70