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openalex
Elizabeth L. Bell, William Finnigan, Scott P. France, Anthony P. Green 等
2021-06-24
置信度 0.72
BiocatalysisBiochemical engineeringComputer scienceSynthetic biologyNanotechnology
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High Resolution Image Download MS PowerPoint Slide Lipases are a group of enzymes capable of catalyzing the hydrolysis of triacylglycerides into free fatty acids during lipid metabolism. In the presence of short-chain alcohols, some of these enzymes can cataly…
openalex
Jeng Yeong Chow, Kimberly Li Shi Choo, Yan Ping Lim, Lay Hiang Ling 等
2021-09-23
置信度 0.72
BiodieselTrioleinBiodiesel productionTransesterificationLipase
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The success of AlphaFold in protein structure prediction highlights the power of data-driven approaches in scientific research. However, developing machine learning models to design and engineer proteins with desirable functions is hampered by limited access t…
openalex
Lihao Fu, Yuan Gao, Yongcan Chen, Yanjing Wang 等
2024-11-07
置信度 0.72
Cloud computingCapeSynthetic biologyComputational biologyBiology
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Biofoundries provide an integrated infrastructure to enable the rapid design, construction, and testing of genetically reprogrammed organisms for biotechnology applications and research. Many biofoundries are being built and a Global Biofoundry Alliance has re…
openalex
Freemont, Paul S., Patron, Nicola J, Carrasco, Jose A., Herrgård, Markus J. 等
2019-05-09
置信度 0.72
AllianceBusinessPolitical scienceGenetically engineeredKey (lock)
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Biomass refining methods aim to convert these feedstocks into valuable bio-based chemicals and fuels through conventional processes. In this way, the refining of sugars and lignin is essential for the development of sustainable processes. The sugars-first appr…
openalex
Lucas Ramos, Jesus Jimenez Ascencio, James Villar, Mónica Ma. Cruz‐Santos 等
2026-02-13
置信度 0.72
BiorefiningBioproductsRefining (metallurgy)Biomass (ecology)Biofuel
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europepmc
2025
置信度 0.80
-
Extensive reference on the integration of biofoundry techniques with lignocellulose biorefinery processes Biofoundry Techniques for Biotechnology Applications presents concepts, perspectives, and technical advancements on thermochemical and biochemical pathway…
openalex
2026-02-13
置信度 0.72
BiorefineryBiomanufacturingBioprocessEngineeringBiotechnology
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Abstract This article examines the convergence of synthetic biology and artificial intelligence (SynBioAI), focusing on co-evolving biosecurity threats as a novel security problem. Advances in genome-editing, CRISPR, AI-powered protein design, and automated bi…
openalex
Nik Hynek
2025-09-01
置信度 0.72
FrontierConvergence (economics)Political scienceEconomicsLaw
-
openalex
Nilmani Singh, Junyu Chen, Jingxia Lu, Aurosish Sharma 等
2025-01-01
置信度 0.72
WorkflowData scienceComputer scienceEngineeringApplications of artificial intelligence
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International proponent literature legitimates biofoundries (the automated infrastructure of synthetic biology) through democratization rhetoric. That register has bifurcated since 2015 and faced a parallel strategic-asset register since 2022. How Korean stake…
openalex
Joonhyung Bae, Dae-hee Lee
2026-05-20
置信度 0.72
DemocratizationFraming (construction)Critical discourse analysisPolitical scienceBase erosion and profit shifting
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In recent years, the design–build–test–learn (DBTL) cycle has become a key concept in strain engineering. Modern biofoundries enable automated DBTL cycling using robotic devices. However, both highly automated facilities and semi-automated facilities encounter…
openalex
Lorena Hägele, Brian F. Pfleger, Ralf Takors
2024-09-03
置信度 0.72
RoboticsArtificial intelligenceComputer scienceComputational biologyEngineering
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Biofoundries significantly enhance the efficiency of microbial strain development for protein production by incorporating advanced genetic engineering, high-throughput screening, and automation. The development of alternative proteins, such as single-cell prot…
openalex
Simab Kanwal, Sher Zaman Safi, Aphichart Karnchanatat, Piroonporn Srimongkol
2026-02-13
置信度 0.72
Metabolic engineeringBacillus subtilisSynthetic biologyBiochemical engineeringBiotechnology
-
The goal of achieving greenhouse gas emissions neutrality has intensified the search for fuels and chemicals from renewable sources. In this context, lignocellulosic biomass increasingly contributes to the transition to a bioeconomy. This chapter delves into t…
openalex
Yaimé Delgado‐Arcaño, Alisson Dias da Silva Ruy, Leila Maria Aguilera Campos, Oscar Daniel Valmaña‐García
2026-02-13
置信度 0.72
Biomass (ecology)Lignocellulosic biomassGreenhouse gasLife-cycle assessmentBiofuel
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crossref
Mingyan Tian, Sarah Sterman
2026-07-13T15:29:49Z
置信度 0.70
-
openalex
Alex Hoose, Richard Vellacott, Marko Storch, Paul S. Freemont 等
2023-01-23
置信度 0.72
Synthetic biologyDNA sequencingDNADNA synthesisComputational biology
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Isotopically non-stationary metabolic flux analysis (INST $^{13}$C-MFA) provides unique insights into cellular physiology but is typically limited by low throughput and high experimental costs. Here, we present a miniaturized and automated workflow that integr…
arxiv
Jochen Nießer, Anton Stratmann, Martin Beyß, Wolfgang Wiechert 等
2026-05-24T16:27:40Z
置信度 0.78
q-bio.QM
-
Precision fermentation relies on microbial cell factories to produce sustainable food, pharmaceuticals, chemicals, and biofuels. Specialized laboratories such as biofoundries are advancing these processes using high-throughput bioreactor platforms, which gener…
arxiv
Txell Amigó, Shawn Zheng Kai Tan, Angel Luu Phanthanourak, Sebastian Schulz 等
2026-02-18T09:29:30Z
置信度 0.78
q-bio.OTcs.AIcs.CL
-
crossref
2022-10-21T04:06:38Z
置信度 0.70
-
crossref
2023-11-09T14:00:18Z
置信度 0.70
-
crossref
2024-07-08T08:30:26Z
置信度 0.70
-
crossref
2025-05-07T09:50:48Z
置信度 0.70
-
crossref
Di Liu
2024-09-11T20:18:29Z
置信度 0.70
-
crossref
Sahana Ghosh
2025-08-07T12:52:18Z
置信度 0.70
-
europepmc
2025
置信度 0.80
-
crossref
2024-02-08T05:50:15Z
置信度 0.70
-
Abstract Biofoundries are automated high-throughput facilities specialising in the design, construction and testing of engineered/synthetic DNA constructs (plasmids), often from genetic parts. A critical step of this process is assessing the fidelity of the as…
crossref
Peter Vegh, Sophie Donovan, Susan Rosser, Giovanni Stracquadanio 等
2023-09-21T00:00:16Z
置信度 0.70
-
crossref
2022-02-15T15:45:15Z
置信度 0.70
-
crossref
A Kondo
2025-07-07T19:26:50Z
置信度 0.70
-
crossref
Sandeep Dinday
2026-06-17T08:04:46Z
置信度 0.70
-
Abstract Glycosyltransferases (GTs) are a large family of enzymes that catalyze glycosidic linkages formation between chemically diverse donor and acceptor molecules to regulate diverse cellular processes across all domains of life. Despite their importance, t…
crossref
Ruili Fang, Lan Na, Charles J. Corulli, Pradeep K. Prabhakar 等
2026-03-17T21:35:12Z
置信度 0.70
-
crossref
Dipendra Wagle, Pedro Arce, Andrea Arce-Trigatti, Robby Sanders
2025-08-21T20:42:46Z
置信度 0.70
-
crossref
Samatha Paladugu, Sarepalli Sai Sathwik, Mamatha Potu
2026-02-13T21:19:58Z
置信度 0.70
-
crossref
Samatha Paladugu, Sarepalli Sai Sathwik, Sreelatha Beemagani
2026-02-13T21:19:58Z
置信度 0.70
-
crossref
Andreza A. Longati, Christian de Oliveira Martins, Gabriel Baioni, Adilson José da Silva 等
2026-02-13T21:19:58Z
置信度 0.70
-
crossref
Fabricio M. Gomes, Messias Borges Silva, Giovani Maltempi‐Mendes, Anuj Kumar Chandel
2026-02-13T21:19:58Z
置信度 0.70
-
europepmc
2025
置信度 0.80
-
crossref
Carlos Lopez‐Ortiz, Alan Chavez‐Hita Wong, Aldo Sosa, Nagamani Balagurusamy
2026-02-13T21:19:58Z
置信度 0.70
-
Abstract Background Efficient conversion of plant biomass to commodity chemicals is an important challenge that needs to be solved to enable a sustainable bioeconomy. Deconstruction of biomass to sugars and lignin yields a wide variety of low molecular weight …
crossref
George L. Peabody, Joshua R. Elmore, Jessica Martinez-Baird, Adam M. Guss
2019-12-23T03:02:18Z
置信度 0.70
-
crossref
José Daniel Cano Montoya, Diego Hernandez, Josman Velasco
2026-02-13T21:19:58Z
置信度 0.70
-
crossref
Shruti Ahlawat, Somya Gupta, Ritika Yadav, Krishna Kant Sharma
2026-02-13T21:19:58Z
置信度 0.70
-
Abstract Glycans are complex carbohydrates that exhibit extraordinary structural complexity and stereochemical diversity while playing essential roles in many biological processes, including immune regulation, pathogen recognition, and cell communication. In h…
crossref
Chin Huang, Natarajan Kannan, Kelley W Moremen
2025-08-28T11:18:44Z
置信度 0.70
-
crossref
Sounak Maitra, Muskaan Sethi, Prisha Inani, Palak Shrivastava 等
2026-02-13T21:19:58Z
置信度 0.70
-
Production of fuels and chemicals from renewable lignocellulosic feedstocks is a promising alternative to petroleum-derived compounds. Due to the complexity of lignocellulosic feedstocks, microbial conversion of all potential substrates will require substantia…
crossref
Julie E. Chaves, Gerald N. Presley, Joshua K. Michener
2019-04-24T03:14:28Z
置信度 0.70
-
crossref
Yan Chen, Deepanwita Banerjee, Aindrila Mukhopadhyay, Christopher J Petzold
2020-01-08T16:41:07Z
置信度 0.70
-
crossref
Katarina Mihajlovski, Nevena Ilić, Galina Jevđenović, Marija Milić
2026-02-13T21:19:58Z
置信度 0.70
-
europepmc
2025
置信度 0.80
-
crossref
Lucas Ramos, Carina Prado, Maria Teresa Ferreira Ramos Raimundo, Uirajá C. M. Ruschoni 等
2026-02-13T21:19:58Z
置信度 0.70
-
Abstract Non-model microorganisms often possess complex phenotypes that could be important for the future of biofuel and chemical production. They have received significant interest the last several years, but advancement is still slow due to the lack of a rob…
crossref
Lauren A. Riley, Adam M. Guss
2021-01-25T12:06:05Z
置信度 0.70
-
europepmc
2026
置信度 0.80
-
crossref
Danielle Matias Rodrigues, Paula Zaghetto de Almeida, Allan H. Félix de Mélo, Juliana Velasco de Castro Oliveira 等
2026-02-13T21:19:58Z
置信度 0.70
-
europepmc
2026
置信度 0.80
-
crossref
Yuankai Huo, Ruining Deng, Quan Liu, Agnes B. Fogo 等
2021-02-10T20:42:42Z
置信度 0.70
-
Abstract Low efficiency of DNA integration into the chromosome limits multiplexed bacterial genetic engineering. We address this by establishing multiplexed Serine recombinase-Assisted Genome Engineering (mSAGE), enabling simultaneous, site-specific insertion …
crossref
Jay D. Huenemann, Austin L. Carroll, Joshua R. Elmore, Gara N. Dexter 等
2025-07-12T04:05:16Z
置信度 0.70
-
Bacteria sense and respond to their environments using a sophisticated array of sensors and regulatory networks to optimize their fitness and survival in a constantly changing environment. Understanding how these regulatory and sensory networks work will provi…
crossref
Peter E. Larsen, Sarah Zerbs, Philip D. Laible, Frank R. Collart 等
2018-06-18T11:06:39Z
置信度 0.70
-
europepmc
2026
置信度 0.80
-
crossref
Lucia Ambrosio, Jacqueline S. Williams, Alfredo Gutierrez, Emily A. Swanson 等
2020-11-10T11:21:21Z
置信度 0.70
-
europepmc
2025
置信度 0.80
-
In this work we demonstrate the endcapping of a poly(beta-amino ester) of polysarcosine, a widely established PEG-alternative, and show its ability as a non-viral vector for self-amplifying mRNA.
crossref
Hulya Bayraktutan, Rafał J. Kopiasz, Amr Elsherbeny, Magda Martinez Espuga 等
2024-04-11T08:40:41Z
置信度 0.70
-
crossref
Jeffrey J Czajka, Burak Okumuş, Mattheos AG Koffas, Mark Blenner 等
2020-09-29T04:14:35Z
置信度 0.70
-
europepmc
2026
置信度 0.80
-
crossref
Jacob Beal, Brian Teague, John T. Sexton, Sebastian Castillo-Hair 等
2022-02-14T07:47:17Z
置信度 0.70
-
Abstract Efficient conversion of pentose sugars remains a significant barrier to the replacement of petroleum-derived chemicals with plant biomass-derived bioproducts. While the oleaginous yeast Rhodosporidium toruloides (also known as Rhodotorula toruloides )…
crossref
Samuel T. Coradetti, Paul A. Adamczyk, Di Liu, Yuqian Gao 等
2023-08-03T06:02:09Z
置信度 0.70
-
Abstract Under nutrient starvation conditions, many microorganisms such as Pseudomonas putida store excess carbon in medium-chain-length polyhydroxyalkanoate ( mcl -PHA) granules. Biosynthesis of PHAs from the fatty acid biosynthetic pathway requires PhaG, whi…
crossref
A. R. Ola Pasternak, Walter T. Woodside, Eugene Kuatsjah, Sekgetho C. Mokwatlo 等
2025-12-19T04:10:31Z
置信度 0.70
-
crossref
Naresh Pandey, Steffi A. Davison, Malathy Krishnamurthy, Daniel S. Trettel 等
2022-09-21T20:42:52Z
置信度 0.70
-
crossref
Andrea Harrison, Josie G. Eder, Priscila M. Lalli, Nathalie Munoz 等
2024-07-16T20:52:11Z
置信度 0.70
-
europepmc
2025
置信度 0.80
-
crossref
Shoaib Raza Khan, Md Muzahid Khan, Kartika Srivastava, Hongyue Jin 等
2025-05-18T10:23:08Z
置信度 0.70
-
crossref
Jeffrey J. Czajka, Deepanwita Banerjee, Thomas Eng, Javier Menasalvas 等
2022-09-13T03:12:21Z
置信度 0.70
-
europepmc
2025
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
Tricyclic sesquiterpenes are bioactive natural products with broad applications in pharmaceuticals, fragrances, and sustainable aviation biofuels. However, the repertoire of characterized tricyclic sesquiterpene synthases (tSTSs) remains limited. To systematic…
pubmed
Kim SE, Cho YR, Lee HJ, Lee SY 等
2026
置信度 0.82
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
Precision fermentation enables the sustainable synthesis of value-added products by engineering microorganisms into specialized cell factories. Unlike traditional fermentation, food-grade precision fermentation operates within a highly regulated framework rela…
pubmed
Shin J
2026
置信度 0.82
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2025
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80