中医药工具 · 全部实体（第 48 / 100 页）

本页收录第 4701–4800 条，共 10000 条 · 返回 中医药工具 首页

• MODERN SCIENTIFIC FOUNDATIONS OF THE USE OF MEDICINAL PLANTS IN TRADITIONAL CHINESE MEDICINE
  This review examines the modern scientific basis of medicinal plants used in Traditional Chinese Medicine (TCM), focusing on their bioactive constituents, pharmacological properties, safety aspects, and recent advances in scientific research.
  datacite Makhmudkhonova, Naimakhon, Nurimova, Lola, Ilkhomova, Feruza 2026 置信度 0.66
• THERAPEUTIC PROPERTIES OF CURCUMA LONGA (TURMERIC)
  Curcuma longa (commonly known as turmeric) is one of the most widely used medicinal plants in traditional medicine systems such as Ayurveda, Traditional Chinese Medicine, and Unani medicine. Modern scientific research has confirmed numerous pharmacological act…
  datacite Мangliyeva Marjona Rashid qizi 2026 置信度 0.66 Curcuma longa, turmeric, curcumin, antioxidant, anti-inflammatory, medicinal plants, phytotherapy.
• THERAPEUTIC PROPERTIES OF CURCUMA LONGA (TURMERIC)
  Curcuma longa (commonly known as turmeric) is one of the most widely used medicinal plants in traditional medicine systems such as Ayurveda, Traditional Chinese Medicine, and Unani medicine. Modern scientific research has confirmed numerous pharmacological act…
  datacite Мangliyeva Marjona Rashid qizi 2026 置信度 0.66 Curcuma longa, turmeric, curcumin, antioxidant, anti-inflammatory, medicinal plants, phytotherapy.
• De-identified outpatient prescription dataset of a TCM master (Prof. ZHAO Hanqing M.D., Ph.D., 2025): 335 prescriptions with 5,951 herb-level records
  Background: Complete outpatient herbal prescription records of Professor Zhao Hanqing , January–December 2025, TCM Internal Medicine department, Heniantang Clinic. Contents: 5,951 herb-level records; 335 prescriptions; 122 de-identified patients; 438 unique he…
  datacite ZHAO, Hanqing 2026 置信度 0.66 traditional Chinese medicineprescription datasetherb co-prescriptionde-identified clinical data
• Effects of containing serum from Hedysari Radix and Astragali Radix before and after honey-processing paired with vinegar-processed Curcumae Rhizoma on the proliferation, migration and invasion of lung cancer cells-Original Data
  The data includes Cisplatin concentration screening, clone formation rate, migration and invasion, cycle, etc.
  datacite ma ding cai 2026 置信度 0.66 Traditional chinese medicineClone formation ratemigration and invasioncycle
• A COMPREHENSIVE REVIEW ON PHYTOCHEMISTRY AND PHARMACOLOGICAL ACTIVITIES OF GINKGO BILOBA
  Ginkgo biloba, often referred to as the maidenhair tree, is among the oldest living plant species and has been widely utilized in traditional medicine, especially within Chinese health practices. Herbal remedies remain significant in contemporary medicine beca…
  datacite Smrutiranjan Dash, Aastha Agrawal 2026 置信度 0.66 Gingko BilobaPhytochemicalPharmacologicalMorphological
• A COMPREHENSIVE REVIEW ON PHYTOCHEMISTRY AND PHARMACOLOGICAL ACTIVITIES OF GINKGO BILOBA
  Ginkgo biloba, often referred to as the maidenhair tree, is among the oldest living plant species and has been widely utilized in traditional medicine, especially within Chinese health practices. Herbal remedies remain significant in contemporary medicine beca…
  datacite Smrutiranjan Dash, Aastha Agrawal 2026 置信度 0.66 Gingko BilobaPhytochemicalPharmacologicalMorphological
• Review Article on Pharmacognostic and Pharmacological Study and The Various Activity of Curculigo Capitulata
  Curculigo Capitulata (Lour.) O. kuntze is a perennial medicinal herb that is found in tropical regions of Asia, Africa, Australia, and the Americas. It is a member of the Hypoxidaceae family (often categorized under Amaryllidaceae). The herb has long been used…
  datacite Nishant Sharma1, Naveen Kumar*2, Abhishek Soni1, Vineet Kapoor1 2026 置信度 0.66 Osteoporosis; Curculigo capitulata; Hypoxidaceae; ethnomedicine; phytochemistry; norlignans; phenolic glycosides; pharmacological activity
• Review Article on Pharmacognostic and Pharmacological Study and The Various Activity of Curculigo Capitulata
  Curculigo Capitulata (Lour.) O. kuntze is a perennial medicinal herb that is found in tropical regions of Asia, Africa, Australia, and the Americas. It is a member of the Hypoxidaceae family (often categorized under Amaryllidaceae). The herb has long been used…
  datacite Nishant Sharma1, Naveen Kumar*2, Abhishek Soni1, Vineet Kapoor1 2026 置信度 0.66 Osteoporosis; Curculigo capitulata; Hypoxidaceae; ethnomedicine; phytochemistry; norlignans; phenolic glycosides; pharmacological activity
• ANTI-DIABETIC ACTIVITY OF ANDROGRAPHIS PANICULATA
  Abstract Andrographis paniculata is a well-known medicinal herb extensively used in traditional systems of medicine, including Ayurveda, Siddha, Unani, and Traditional Chinese Medicine. The plant is recognized for its broad spectrum of pharmacological properti…
  datacite Dr. Ganesh Guguloth 2026 置信度 0.66 Andrographis paniculatadiabetes mellitusandrographolidemedicinal plantsantioxidant activity
• ANTI-DIABETIC ACTIVITY OF ANDROGRAPHIS PANICULATA
  Abstract Andrographis paniculata is a well-known medicinal herb extensively used in traditional systems of medicine, including Ayurveda, Siddha, Unani, and Traditional Chinese Medicine. The plant is recognized for its broad spectrum of pharmacological properti…
  datacite Dr. Ganesh Guguloth 2026 置信度 0.66 Andrographis paniculatadiabetes mellitusandrographolidemedicinal plantsantioxidant activity
• Forging Peace between Europe and Russia: Healing Historical Trauma for Mutual Prosperity and Happiness
  Preface: A Shared Heritage of Cooperation In the year 1051, a remarkable woman arrived in Paris to begin a new chapter in European history. Anna Yaroslavna, the highly educated daughter of Kyivan Rus Grand Prince Yaroslav the Wise, stepped from her carriage to…
  datacite Hoicka, David 2025 置信度 0.66 mediationEuropetraumaHistorical Traumarussia
• Forging Peace between Europe and Russia: Healing Historical Trauma for Mutual Prosperity and Happiness
  Preface: A Shared Heritage of Cooperation In the year 1051, a remarkable woman arrived in Paris to begin a new chapter in European history. Anna Yaroslavna, the highly educated daughter of Kyivan Rus Grand Prince Yaroslav the Wise, stepped from her carriage to…
  datacite Hoicka, David 2025 置信度 0.66 mediationEuropetraumaHistorical Traumarussia
• The Mediating Effect of Sleep Quality Between Pain and Life Satisfaction Among Chinese Older Adults: Evidence from CHARLS 2020.
  With the accelerating trend of population aging, increasing attention has been paid to the health status and quality of life among older adults. However, the underlying mechanisms linking pain and life satisfaction remain not fully elucidated. This research in…
  pubmed Ren P, Du Z, Zhang W, Gao T 等 2026 置信度 0.82
• Influence of Oral Collagen Peptides on Skin Biophysical Properties in Humans: A Narrative Review.
  The skin not only provides protection and sensory functions for the body, but healthy skin also enhances self-esteem. Moreover, altered cutaneous function contributes to the development of extracutaneous disorders. Therefore, great efforts have been made to id…
  pubmed Lei D, Zhang G, Guo T, Zhang L 等 2026 置信度 0.82
• Efficacy and safety of microfragmented adipose tissue versus platelet-rich plasma, hyaluronic acid and saline for knee osteoarthritis.
  To compare the efficacy and safety of intra-articular microfragmented adipose tissue (MFAT) injection with platelet-rich plasma (PRP), hyaluronic acid (HA), and saline injection for knee osteoarthritis treatment.
  pubmed Zhao D, Chen SC, Liu ZT, Huang ZX 等 2026 置信度 0.82
• Case Report: A rare case of multiple gastrointestinal autoimmune disorders mimicking autoimmune polyglandular syndrome type 3B.
  Autoimmune polyglandular syndrome type 3 (APS-3) encompasses autoimmune thyroid disease and other autoimmune disorders. APS-3B involving gastrointestinal autoimmune diseases. In this case, due to the coexistence of multiple autoimmune diseases including ulcera…
  pubmed Zhang Z, Xie Y, Zhang T, Li X 等 2026 置信度 0.82
• A biomarker-guided framework for corticosteroid treatment stratification in acute exacerbation of idiopathic pulmonary fibrosis.
  Acute exacerbation of idiopathic pulmonary fibrosis is a fatal acute-on-chronic respiratory event with limited evidence-based treatment options. Systemic corticosteroids remain widely used, yet their benefit in unselected patients is uncertain, and indiscrimin…
  pubmed Chen Q, Zhang Y, Li J, Zhu Q 等 2026 置信度 0.82
• Favorable response to second-line sirolimus regardless of STAT3/5b status in acquired pure red cell aplasia: A retrospective study from a single center.
  Cyclosporine A (CsA) is the standard first-line treatment for acquired pure red cell aplasia (PRCA), but outcomes vary. Effective salvage strategies for CsA-refractory patients, particularly those with complex secondary subtypes, remain inadequately defined. A…
  pubmed Sun Z, Jia X, Shen Y, Yang X 等 2026 置信度 0.82
• BDE47 exposure in lung adenocarcinoma: prognostic biomarkers, immune dysregulation, and mechanistic insights from toxicogenomic and docking studies.
  Growing evidence links 2, 2', 4, 4'-tetrabromodiphenyl ether (BDE47), a common environmental pollutant, to various health risks. This study examines the shared genetic markers between BDE47 exposure and lung adenocarcinoma, analyzes their biological roles, and…
  pubmed Zhao M, Wu X, Mao Y, Wu M 等 2026 Sep 置信度 0.82
• GLGZG improves post-stroke spastic paralysis in rats through regulating BDNF/TrkB signaling.
  Stroke is the second leading cause of disability and death worldwide and imposes a significant burden on society. Post-stroke spastic paralysis (PSP) is one of the most common sequelae of stroke, severely affecting patients' limb function and rehabilitation an…
  pubmed Gao L, Jia Y, Zhou LL, Hong W 等 2026 Sep 置信度 0.82
• Targeting the CD47-SIRPα Axis in Atherosclerosis: From Pathogenesis to Therapeutic Implications.
  Atherosclerosis (AS), the pathological basis of cardiovascular diseases, remains a leading global cause of mortality. Its pathogenesis involves chronic inflammation, impaired clearance of apoptotic cells (efferocytosis), and lipid dysregulation within the arte…
  pubmed Sun C, Hu L, Yuan Y, Zhou K 等 2026 置信度 0.82
• Borneol-based nanoparticles encapsulating Doxorubicin/Sodium tanshinone IIA sulfonate enhance the effect of anti-glioma and alleviate cardiotoxicity.
  Clinical treatment of brain glioma remains challenging due to chemotherapeutic resistance, cardiotoxicity and the presence of blood-brain barrier (BBB). Advanced nanoplatforms that can cross the BBB efficiently and target brain glioma with lower cardiotoxicity…
  pubmed Ye X, Li J, Song Q, He J 等 2026 Oct 置信度 0.82
• Targeting eEF1A1 With Baicalein to Block eEF1A1/Prdx4 Interaction for Treating Sepsis-Mediated Lung Injury.
  Sepsis is a systemic inflammatory response syndrome triggered by an uncontrolled host response to infection, which causes acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Baicalein (Bai) is one of the major active components of Scutellar…
  pubmed Chang J, Zhang HL, Zhu QM, Hui SW 等 2026 Aug 24 置信度 0.82
• Body mass index-related heterogeneity in diaphragm thickening fraction response to exercise training in stable chronic obstructive pulmonary disease.
  Diaphragmatic dysfunction contributes to exercise intolerance in COPD, but whether BMI shapes baseline function and response to exercise remains unclear. This secondary analysis characterized BMI-related diaphragmatic phenotypes and whether diaphragm thickenin…
  pubmed Wang Y, Bao Y, Deng X, Duan H 等 2026 置信度 0.82
• A 1:1 matched-pair comparative study of minimally invasive elastic Poller wire augmentation vs. standard augmentative plating for hypertrophic femoral non-union after intramedullary nailing.
  The primary cause of hypertrophic non-union following femoral intramedullary nailing (IMN) is mechanical instability rather than the depletion of biological activity. Although standard augmentative plating can provide excellent stability, it typically necessit…
  pubmed Zhao J, Zhang Z, Lin J, Feng G 等 2026 置信度 0.82
• Pro-inflammatory diet in pregnancy associated with increased risk of abnormal perinatal outcomes: evidence from dietary inflammatory index in the UK biobank.
  This study aimed to investigate the association between a pro-inflammatory diet in pregnancy, assessed via the Dietary Inflammatory Index (DII), and abnormal perinatal outcomes (APOs), including miscarriage and stillbirth. Leveraging the UK Biobank cohort, we …
  pubmed Sheng L, He W, Wang F, Weng X 等 2026 置信度 0.82
• Commentary: Acupoint glucocorticoid injection combined with focused ultrasound for granulomatous lobular mastitis: a retrospective study.
  pubmed Zhu L, Shen S 2026 置信度 0.82
• Network pharmacology-based prediction and experimental validation of the anti-hyperuricemic effects of oolong tea polyphenols.
  This study aimed to identify candidate therapeutic targets of oolong tea polyphenols (TP) against hyperuricemia (HUA) using network pharmacology and bioinformatics, and to validate the predicted molecular mechanism through in vivo experimentation.
  pubmed Lin F, Lu D, Chen J, Liu X 等 2026 置信度 0.82
• Multifaceted mechanisms of unconventional T cells in ischemia-reperfusion injury.
  Ischemia-reperfusion injury (IRI) constitutes a common pathological basis for organ dysfunction across various critical clinical conditions, including ischemic stroke, myocardial infarction, and organ transplantation. This review focuses on the functions of un…
  pubmed Li J, Lin P, Yuan M, Wang Y 等 2026 置信度 0.82
• Multidimensional feature fusion in longitudinal physical examination data: a machine learning framework for classification of type 2 diabetes.
  Machine learning-based risk classification of type 2 diabetes mellitus (T2DM) has become a prevailing research direction in intelligent healthcare. Nevertheless, current studies suffer from two key limitations. First, most existing models are built on cross-se…
  pubmed Zhou Y, Sun B, Cai X, Qi J 2026 置信度 0.82
• Exploring dynamic changes in metabolic profiles of Artemisia argyi leaves across different growth stages via plant metabolomics.
  Artemisia argyi Levl. et Vant is a traditional Chinese medicinal herb with considerable medicinal value. A. argyi Levl. et Vant. leaves (AAL) have exhibited diverse biological activities that are tightly associated with their chemical components. During growth…
  pubmed Zhong Y, Ren Y, Zhang J, Liu J 等 2026 置信度 0.82
• Engeletin alleviates MSU-induced inflammatory and tubular injury in vitro by targeting TLR4 and NFKB1.
  The possible mechanisms of engeletin in hyperuricemic nephropathy (HN) has remained obscured; consequently, this investigation seeks to illuminate both the therapeutic potential and the mechanistic underpinnings of engeletin within the context of HN in vitro. …
  pubmed Han R, Wu C, Liang X, Xiang X 等 2026 Oct 置信度 0.82
• Embodied robots in rehabilitation-oriented interventions for older adults with disability or cognitive impairment: a scoping review.
  Robots are increasingly used in later-life care. However, existing reviews often combine applications such as companionship, telepresence, medication support, monitoring, psychosocial support, traditional AI, and rehabilitation within a single body of evidence…
  pubmed Xu W, Zhou X, Zeng Y, Han S 等 2026 置信度 0.82
• Research progress on the classification and clinical response strategies for "complex ductoscopy operating procedure".
  To systematically review the literature on ductoscopy-related operative failures, establish a classification system for "Complex Ductoscopy Operating Procedure (CDOP)", and propose standardized clinical response strategies.
  pubmed Zheng J, Tang Y, Gao Y, Sun Y 等 2026 置信度 0.82
• Effect of music-guided breathing training combined with singing on pulmonary rehabilitation in COPD patients: a randomized controlled trial protocol.
  Pulmonary rehabilitation (PR) is effective for improving symptoms and functional status in patients with chronic obstructive pulmonary disease (COPD), particularly respiratory training. However, its effectiveness is often compromised by poor adherence. Music t…
  pubmed Xue Y, Wang Z, Yuan Z, He X 等 2026 置信度 0.82
• Serum sCD163 as a potential biomarker for predicting poor functional outcome at 3 months in acute ischemic stroke without reperfusion: a prospective study.
  Neuroinflammation plays a critical role in the prognosis of acute ischemic stroke (AIS). Soluble CD163 (sCD163), a marker of monocyte/macrophage activation, has been linked to stroke severity, but its independent prognostic value and clinical utility remain un…
  pubmed Yan M, Shao L, Li Z, Liu C 2026 置信度 0.82
• Development of camellia oil-based beverage and its anti-atherosclerotic effects in ApoE(-/-) mice.
  Atherosclerosis remains a leading cause of cardiovascular morbidity and mortality worldwide. Although camellia oil exhibits promising anti-atherosclerotic properties, its direct consumption is often limited by its strong flavor and greasy texture.
  pubmed Zhang W, Yang N, Wen B, Qin L 等 2026 置信度 0.82
• Graves' disease following immunosuppression withdrawal and SARS-CoV-2 infection in a failed kidney allograft recipient: a case report on immune reconstitution.
  Immune recovery after withdrawal of long-term immunosuppression may unmask autoimmune disease, but thyroid autoimmunity in patients with failed kidney allografts remains poorly characterized. We report a 29-year-old man with kidney allograft failure who develo…
  pubmed Yang N, Wu X, Zhao L, Hu S 等 2026 置信度 0.82
• Does ovarian stimulation accelerate the progression of BI-RADS categories? a propensity score matching-based retrospective cohort study.
  To investigate whether controlled ovarian stimulation (COS), as part of assisted reproductive technology (ART), accelerates the progression of BI-RADS categories.
  pubmed Wang T, Ren J, Qi Z, Zhao S 等 2026 置信度 0.82
• Type 2 diabetes mellitus is associated with distinct post-treatment metabolic profiles in pulmonary tuberculosis.
  Type 2 diabetes mellitus (T2DM) is a major risk factor for pulmonary tuberculosis (PTB), exacerbates disease severity and reduces the efficacy of anti-tuberculosis therapy. Previous studies have shown that T2DM is associated with exacerbated metabolic disturba…
  pubmed Li X, He Z, Gao Q, Hou Z 等 2026 置信度 0.82
• Effect of rapid antiretroviral therapy initiation on loss to follow-up, virologic failure, and immunologic failure among people living with HIV under the treat-all policy in China: a retrospective cohort study (2016-2023).
  Since 2016, China has fully implemented the Treat-All policy, which eliminated the CD4 cell count threshold and ensures timely antiretroviral therapy (ART) for all people living with HIV (PLWH). This study aimed to evaluate the impact of rapid ART initiation (…
  pubmed Ao S, Zheng Y, Yang L, Nie Z 等 2026 置信度 0.82
• Early cardia neoplasms in the upper gastrointestinal tract have a higher detection rate under sedation: a retrospective cohort study based on the Chinese population.
  Esophagogastroduodenoscopy (EGD) is a standard method for upper gastrointestinal (UGI) tumor screening. However, differing opinions persist regarding the impact of sedation on the detection rate of early adenocarcinoma of the gastric cardia (EGCA). This study …
  pubmed Chen X, Zhou S, Feng M, Shi C 等 2026 置信度 0.82
• Sex inequality in disease burden attributable to smoking, secondhand smoke and chewing tobacco: A systematic analysis for the Global Burden of Disease Study 2023.
  Despite extraordinary progress in global tobacco control and prevention, smoking, secondhand smoke (SHS) and chewing tobacco continue to profoundly impact public health, affecting males and females differently. Existing studies have not systematically characte…
  pubmed Li S, Xu Z, Morgan B, Li D 等 2026 Sep 置信度 0.82
• ReliST: A model-agnostic risk layer for spatial transcriptomics deconvolution.
  Spatial transcriptomics deconvolution maps cell-type abundance across tissue, but most outputs do not indicate which local predictions can be trusted. We developed ReliST, a model-agnostic risk layer that preserves base predictions while assigning spot-level r…
  pubmed Zhang X, He L, Peng Y, Li Y 等 2026 置信度 0.82
• Circular Loop Ligation for Securing Endobronchial Valve in the Treatment of Bronchial Stump Fistula.
  Bronchial stump fistula (BSF), which is located on the bronchial stump following pulmonary resection, represents a distinct subtype of bronchopleural fistula (BPF). Although the endobronchial valve (EBV) has been used to treat BPF, few clinical studies involve…
  pubmed Wang L, Xu J, He Z, Xin S 等 2026 置信度 0.82
• Integrative Single-Cell and Spatial Transcriptomics Identifies CRIP1(+) Prehypertrophic Chondrocytes as Inflammatory Hubs and a Valuable Diagnostic Biomarker for Osteoarthritis.
  Osteoarthritis (OA) is a prevalent degenerative joint disease characterized by progressive cartilage destruction, yet the heterogeneity of transitional chondrocyte states and their contributions to pathogenesis remain incompletely understood. In this study, we…
  pubmed Xie Z, Wang Y, Liu J, Li H 等 2026 置信度 0.82
• A Crown Ether-Based LCST Molecule With Cation Size Selective Matching Capability for Efficient Management of Solar Radiation.
  Supramolecular matter exhibiting a lower critical solution temperature (LCST) represents a typical class of thermo-responsive systems with controllable phase separation performance, and they have attracted widespread attention. Herein, we report a novel crown …
  pubmed Chen S, Tao Y, Wang M, Du G 等 2026 Aug 25 置信度 0.82
• Pogostemon cablin essential oil: a food-grade natural product attenuating heatstroke-induced multi-organ injury via intestinal barrier reinforcement and macrophage polarization modulation.
  Climate change-induced heatstroke (HS) presents a critical global public health threat, necessitating the development of preventive strategies using natural, food-derived resources. Pogostemon cablin (patchouli) is a medicinal and edible dual-purpose resource …
  pubmed Li R, Liu L, Chen X, Wang Z 等 2026 Aug 25 置信度 0.82
• Reduced-exposure neuromuscular blockade strategies for total laparoscopic hysterectomy within an ERAS pathway: a randomized controlled trial.
  Neuromuscular blocking agents (NMBAs) facilitate tracheal intubation and laparoscopic exposure, but residual neuromuscular blockade remains a perioperative concern. We evaluated whether reducing NMBA exposure during total laparoscopic hysterectomy within an En…
  pubmed Fan Q, Ge L, Kong L, Wu Z 等 2026 Jul 23 置信度 0.82
• Design, Synthesis, and Structure-Activity Relationship Studies of Novel 3CL(pro) Inhibitors.
  The SARS-CoV-2 3C-like protease (3CL pro ) is an essential enzyme for coronavirus replication and remains an attractive antiviral target due to its high sequence conservation among coronaviruses. Based on a previously identified catechol-containing covalent 3C…
  pubmed Feng Y, Wang F, Liu D, Yan Q 等 2026 Aug 27 置信度 0.82
• Integrated bulk and single-cell transcriptomic analyses identify senescence-related hub genes and microenvironmental remodeling in sarcopenia.
  Increasing evidence indicates that cellular senescence, metabolic dysfunction, stromal remodeling, and immune perturbation collectively contribute to disease progression. However, senescence-related biomarkers with diagnostic potential and microenvironmental r…
  pubmed Chen Y, Ma K, Huang T, Gao J 等 2026 Aug 26 置信度 0.82
• The International Chinese Young Scholars Alliance for the Study of the Liver: facilitating global collaboration.
  pubmed Li W, Cao Z, Yeo YH, Shang Y 等 2026 Aug 25 置信度 0.82
• Research Progress of Diabetes-related Glaucoma: Mechanisms, Impacts and Management Strategies.
  Diabetes mellitus (DM), a highly prevalent metabolic disorder, is increasingly recognised for its significant association with glaucoma, a leading cause of irreversible vision loss. This review systematically synthesises recent advances in understanding DM-rel…
  pubmed He L, Liu J, Yu Y, Hu C 等 2026 Aug 25 置信度 0.82
• A bioorthogonal nanoconcentrisome system for epigenetic and immunometabolic reprogramming of tissue regeneration in aged female rats.
  Stem cell-based therapies show promise for tissue regeneration but are limited by therapeutic instability, particularly in aged tissues. Here, multi-omics profiling of regenerating bone reveals marked depletion of S-adenosylmethionine (SAM), indicating epigene…
  pubmed Zhao L, Zhang Z, Zheng L, Liang Y 等 2026 Jul 23 置信度 0.82
• Corrigendum to "Task-oriented incivility and its impact on nursing students' safety behaviors in intensive care units: A qualitative study" [Nurse Educ. Today 166 (2026) 107178].
  pubmed Li S, Zhu F, Ye C, Xin X 等 2026 Aug 25 置信度 0.82
• [Clinical study of Ilizarov technique combined with "joystick technique" in treatment of fourth brachymetatarsia].
  To evaluate the effectiveness and safety of Ilizarov technique combined with the "joystick technique" for the treatment of fourth brachymetatarsia.
  pubmed Liang J, Feng E, Guan H, Chen P 等 2026 Aug 15 置信度 0.82
• [Development of a nomogram prediction model for re-tear after arthroscopic repair of massive rotator cuff tears].
  To investigate the clinical and imaging factors affecting the re-tear after arthroscopic repair in massive rotator cuff tears, and to develop a nomogram prediction model.
  pubmed Yang Z, Ruan W, Pan W, Li D 等 2026 Aug 15 置信度 0.82
• Olaparib as the first-line maintenance therapy in advanced-stage epithelial ovarian cancer patients with BRCA mutations - Real-world experience from Taiwan.
  Advanced epithelial ovarian cancer frequently recurs despite good response to first-line treatment, making maintenance therapy essential. Olaparib, a poly (ADP-ribose) polymerase (PARP) inhibitor, demonstrated significant benefit in BRCA-mutated disease in the…
  pubmed Tang WJ, Chang SH, Chang CB, Chen WC 等 2026 Sep 置信度 0.82
• Efficacy and safety of glucagon-like peptide-1 receptor agonists for diabetic cardiomyopathy: a protocol for systematic review and meta-analysis.
  Diabetic cardiomyopathy (DCM) is an important contributor to heart failure and death in patients with diabetes. Current management strategies mainly focus on glycaemic control and symptomatic treatment with limited disease-specific therapeutic options availabl…
  pubmed Tang B, Yu Y, Tang Y, Yu R 等 2026 Aug 25 置信度 0.82
• Fuzheng Buxue Dietary Therapy-Preconditioned MSC-Derived Extracellular Vesicles Promote Hematopoietic Recovery in Chemotherapy-Induced Myelosuppression.
  BackgroundChemotherapy-induced myelosuppression (CIM) is a common dose-limiting toxicity that compromises chemotherapy continuity and patient outcomes. In the bone marrow microenvironment, mesenchymal stromal cell-derived extracellular vesicles (MSC-EVs) act a…
  pubmed Yin M, Dong H, Tu W, Yan S 等 2026 Jan-Dec 置信度 0.82
• Serum Pharmacochemistry Combined With Network Pharmacology to Explore Potential Bioactive Components and Mechanisms of Pomegranate Peel in the Treatment of Colorectal Cancer.
  Pomegranate peel (PP) is a traditional Chinese medicinal material. PP has multiple biological activities such as anti-inflammatory and anticancer activities. Although biological activity investigations of PP are growing, few studies have focused on its chemica…
  pubmed Yisimayili Z, Yimamu G, Aimaiti R, Aikemu M 等 2026 置信度 0.82
• Neferine improves sleep quality in chronically sleep-deprived mice by antagonizing OXRs in noradrenergic and serotonergic neurons.
  Orexin receptors (OXRs) have emerged as promising therapeutic targets for insomnia. Our preliminary research suggested that neferine (NEF)-a bisbenzylisoquinoline alkaloid derived from Nelumbinis plumula-is a potential antagonist of OXRs in vitro. However, it …
  pubmed Wang Y, Fang J, He J, Xiao N 等 2026 Aug 25 置信度 0.82
• Integrated metabolomics and proteomics revealed the comprehensive mechanism of Sijunzi decoction and its active components in improving multi-system dysfunction induced by spleen deficiency syndrome.
  Sijunzi decoction (SJZD) is a classic formula in traditional Chinese medicine (TCM) for the treatment of spleen deficiency syndrome (SDS). The chemical composition of SJZD mainly consists of polysaccharides (SJZDP), oligosaccharides (SJZD-OGS), and small-molec…
  pubmed Chen X, Pu Z, Liu Y, Zhang Z 等 2026 Aug 25 置信度 0.82
• Xijiao Dihuang decoction attenuates microglia/macrophage-mediated inflammatory response in cerebral injury by modulating the PI3K/Akt/HIF-1α/NLRP3 axis.
  Xijiao Dihuang Decoction (XJDH), originating from Beiji Qianjin Yaofang (Thousand Gold Prescriptions for Emergencies) compiled by Sun Simiao during the Tang Dynasty (652 AD), is a classical Traditional Chinese Medicine (TCM) formula comprising Cornu Bubali (su…
  pubmed Fang M, Yang J, Gao M, Zhao Y 等 2026 置信度 0.82
• ZiBuPiYin recipe mediates BDNF/TrkB/CREB regulation of synaptic plasticity: Key role of SYT1 acetylation modification.
  ZiBuPiYin recipe (ZBPYR) has been verified to ameliorate insulin resistance, alleviate neuroinflammation, mitigate oxidative stress, and remodel gut microbiota in type 2 diabetes mellitus (T2DM) rats, thereby exerting definite therapeutic efficacy against diab…
  pubmed Xu K, Zhao W, Tang J, Zhang Y 等 2026 置信度 0.82
• Jiu-Wei-Yong-An decoction alleviates atopic dermatitis by suppressing TLR4/MyD88/NF-κB signaling pathway.
  Jiu-Wei-Yong-An (JWYA) decoction is a clinical traditional Chinese medicine prescription for atopic dermatitis (AD). Its anti-inflammatory and anti-pruritic activities have been previously confirmed, yet the underlying molecular mechanism remains unclear.
  pubmed Zhang H, Gu Q, Meng Y, Chen T 等 2026 置信度 0.82
• Dual metabolic and mood-modulating effects of Schisandra chinensis lignans in hyperlipidemic rats: involvement of hepatic PPAR signaling and restoration of central GABAergic signaling.
  Schisandra chinensis (Turcz.) Baill., a traditional Chinese medicinal material documented in the Chinese Pharmacopoeia, has been used for centuries for tranquilizing and hepatoprotective purposes. Its dibenzocyclooctadiene lignans exhibit lipid-regulating prop…
  pubmed Li J, Zhao Y, Chen Z, Wang Y 等 2026 Aug 25 置信度 0.82
• Multimodal MRI signatures and concurrent myelin remodeling alterations in the anterior cingulate cortex correlate with the antidepressant-like effects of 18β-glycyrrhetinic acid in CSDS mice.
  The anterior cingulate cortex (ACC) regulates emotion, and its dysfunction is associated with depression. 18β-glycyrrhetinic acid (18β-GA) exerts robust antidepressant effects; however, its roles in neural circuit remodeling of the ACC and underlyi…
  pubmed Li Y, Ran Y, Ning W, Yao M 等 2026 Aug 25 置信度 0.82
• Spatially restricted antigen expression by an ionizable lipid nanoparticle enhances mRNA vaccine immunity against Pseudomonas aeruginosa.
  Pseudomonas aeruginosa is a major cause of hospital-acquired infections, yet no licensed vaccine is available. Although mRNA-LNP vaccines offer a flexible platform for antibacterial immunization, conventional formulations are primarily optimized for gene expre…
  pubmed Zhang N, Sun Z, Fan L, Miao Y 等 2026 Aug 25 置信度 0.82
• β-sitosterol inhibited hypoxia-related colorectal cancer metastasis by regulating HIF-1α/VEGF pathway.
  This study aimed to investigate how β-sitosterol (SIT) suppresses hypoxia-driven metastasis and angiogenesis in colorectal cancer.
  pubmed Dai L, Meng P, Hu J, Dou H 等 2026 Aug 25 置信度 0.82
• Closed-loop insulin delivery for glycaemic control in hospitalised and perioperative adults: A systematic review and meta-analysis of randomised controlled trials.
  We evaluated whether closed-loop insulin delivery improves glycaemic control in hospitalised and perioperative adults. PubMed/MEDLINE, Embase, CENTRAL, and ClinicalTrials.gov were searched from inception to 29 June 2026 for randomised controlled trials compari…
  pubmed Zhong J, Zhao C, Shuai X, Wang H 等 2026 Aug 25 置信度 0.82
• Interpreting lipoprotein(a) risk across the MASLD disease spectrum.
  pubmed Li D, Hu S, Wu M 2026 Aug 25 置信度 0.82
• Altered brain functional network segregation and integration in patients with insomnia disorder.
  Insomnia disorder (ID) is frequently accompanied by depressive symptoms, complicating clinical management. However, alterations in interregional brain interactions associated with depressive symptoms in patients with ID remain unclear. We enrolled 40 healthy c…
  pubmed Wang H, Ye G, Chen H, Li H 等 2026 Aug 25 置信度 0.82
• High-strength conductive PVA/lignosulfonate/tannic acid/Cu(2+) hydrogel for multifunctional wound dressing.
  Hydrogel wound dressings have evolved from passive moisture barriers into intelligent platforms integrating multiple therapeutic functions. However, reconciling electrical conductivity, mechanical strength, and biocompatibility remains challenging. Herein, we …
  pubmed Wang Y, Li Y, Shi F, Fu Y 等 2026 Aug 25 置信度 0.82
• The protein extracted from fermented Zanthoxylum bungeanum seeds mitigates DSS-induced ulcerative colitis by orchestrating inflammatory cytokine modulation, counteracting oxidative stress, and safeguarding gut microbiota homeostasis.
  Zanthoxylum bungeanum seeds (ZBS) are protein-rich by-products with limited high-value utilization, and fermentation may provide an effective strategy to improve the functional properties and bioactivity of their proteins. In this study, fermented ZBS protein …
  pubmed Gu X, Xu G, Lu X, Mektrirat R 等 2026 Aug 25 置信度 0.82
• Prognostic model based on calcium-related genes predicts prognosis and reveals the immune landscape of acute myeloid leukemia.
  Acute myeloid leukemia (AML) exhibits heterogeneous outcomes and lacks reliable prognostic markers. As a critical regulator of cell fate, calcium signaling's prognostic value in AML requires investigation. This study aims to construct a calcium-related gene (C…
  pubmed Duan J, Zhang H, Chu J, Duan X 2026 Aug 25 置信度 0.82
• Efficacy and Safety of High Tibial Osteotomy Combined with Mesenchymal Stem Cells for Knee Osteoarthritis: A Systematic Review and Meta-Analysis.
  This study aimed to systematically review the clinical efficacy of high tibial osteotomy (HTO) combined with mesenchymal stem cells (MSCs) in the treatment of knee osteoarthritis (KOA) and to provide an updated summary of current evidence and identify gaps in …
  pubmed Zhang W, Ma Y, Lu F, Liang W 等 2026 Aug 25 置信度 0.82
• Mechanism of isoferulic acid in Bai-He-Gu-Jin-Tang inhibiting non-small cell lung cancer by suppressing epidermal growth factor receptor-mediated phosphoinositide 3-kinase/protein kinase B pathway.
  Chemoresistance to paclitaxel (PTX) significantly compromises the prognosis of non-small cell lung cancer (NSCLC) patients. Although Bai-He-Gu-Jin-Tang (BHGJT) shows efficacy against lung diseases, its therapeutic components and mechanisms involved in reversin…
  pubmed Xiao X, Liu F, Ou H, Fang G 等 2026 Aug 20 置信度 0.82
• Ginsenoside Rb1 alleviates isoproterenol- and transverse aortic constriction-induced cardiac fibrosis by suppressing monocyte recruitment via targeting Raf1.
  A major pathological event in heart failure (HF) is cardiac fibrosis induced by pressure overload, and infiltration of monocytes is essential in this scenario. Nevertheless, there are no targeted therapies. Ginsenoside Rb1 (Rb1), a major active component of Pa…
  pubmed Zhao BY, Chen FK, Weng DZ, Li AQ 等 2026 置信度 0.82
• Hongqi Shenmai Decoction ameliorates post-myocardial infarction heart failure by preserving mitochondrial cardiolipin homeostasis via attenuation of EGFR/JAK2-STAT3 signaling.
  Post-myocardial infarction heart failure (post-MI HF) is driven by adverse ventricular remodeling and mitochondrial dysfunction. Cardiolipin is essential for mitochondrial integrity, but its upstream regulation in failing myocardium remains unclear. Whether Ho…
  pubmed Bo H, Liu D, Zhai C, Chen Z 等 2026 置信度 0.82
• Puerarin alleviates memory deficits through the modulation of D‑serine-mediated N-methyl-D-aspartate receptor activity in presenilin 1/2 conditional double knockout mice.
  Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive cognitive decline, the formation of amyloid-β plaques and neurofibrillary tangles, and synaptic dysfunction. Puerarin (PUE), an isoflavone C-glycoside extracted from Pu…
  pubmed Gao W, Hu K, Yang G, Pan J 等 2026 Aug 18 置信度 0.82
• TGF-β1 promotes fibrosis of the ligamentum flavum by inducing FGF-2 release and activating the P38 MAPK pathway to regulate collagen synthesis.
  Ligamentum flavum hypertrophy (LFH) is a primary pathogenic factor of lumbar spinal canal stenosis (LSCS), characterized by fibroblast proliferation and extracellular matrix (ECM) remodeling. While transforming growth factor-β1 (TGF-β1) is a key re…
  pubmed Lu Q, Ye Y, Xie T, Wang X 等 2026 Aug 18 置信度 0.82
• Associations of salinity and microplastics with microbial community assembly and functional potential in saline-alkali soils.
  Soil salinization and microplastic (MP) pollution are important pressures on saline-alkali ecosystems, yet their associations with soil microbial communities along natural salinity gradients remain unclear. We investigated low (LS), medium (MS), and high-salin…
  pubmed Ding C, Hu W, Yang X, Mo G 等 2026 Aug 21 置信度 0.82
• Pyruvate carboxylase promotes progression of endometriosis by activating the AKT pathway.
  Does pyruvate carboxylase drive the progression of endometriosis, and, if so, what is the underlying mechanism?
  pubmed Wu Y, Ye X, Jin O, Liu B 等 2026 Jul 29 置信度 0.82
• Validation of intratumoral necrosis as a prognostic marker in PDAC: Correlation with pathological findings and preoperative MDCT assessment.
  To validate the prognostic significance of intratumoral necrosis in patients with pancreatic ductal adenocarcinoma (PDAC) and evaluate the diagnostic accuracy of preoperative multidetector computed tomography (MDCT) in detecting necrosis.
  pubmed Dong QJ, Zheng F, Zhang CL, Li XG 等 2026 Aug 25 置信度 0.82
• Logic-gated nanoregulators: A paradigm shift from drug delivery to pre-programmed multi-target immunotherapy.
  Cancer immunotherapy has reshaped oncology, yet its broad application is constrained by an immunosuppressive tumor microenvironment and the systemic toxicities of conventional treatments. This review traces the evolution of nanomedicine from a passive drug del…
  pubmed Wu Y, Tang F, Lee J, Liang Y 等 2026 Aug 17 置信度 0.82
• Beta-ketothiolase deficiency: two novel ACAT1 variants and a retrospective study of 76 cases in China.
  Beta-ketothiolase deficiency (BKTD) is a rare genetic metabolic disorder caused by variants in the ACAT1 gene. It can induce severe metabolic acidosis, which may be life-threatening. This study reports two critically ill children with newly diagnosed BKTD and …
  pubmed Deng X, Li X, Liu H, Wang T 等 2026 Aug 19 置信度 0.82
• Comparison and validation of two proposed modifications to the current lymph node classification for esophageal squamous cell carcinoma.
  Accurate lymph node (LN) classification is crucial for prognostic evaluation and individualized management in esophageal squamous cell carcinoma (ESCC).
  pubmed Fu L, Yuan L, Jin D, Yi H 等 2026 Aug 22 置信度 0.82
• Social participation as a modifiable social determinant of health: A systematic review and dose-response meta-analysis of all-cause mortality in older adults.
  To examine the association between social participation and all-cause mortality among older adults, evaluate associations across different types of social participation, and explore the dose-response relationship between monthly participation frequency and mor…
  pubmed Xiao Y, Liu R, Xu X, Liu L 等 2026 Aug 25 置信度 0.82
• Association between hyperhomocysteinemia and frailty in older adults with acute ischemic stroke: A cross-sectional study.
  Frailty is common among patients with acute ischemic stroke (AIS) and is associated with adverse health outcomes. Although hyperhomocysteinemia (Hhcy) is a recognized biomarker in AIS, its association with frailty remains unclear. This study aimed to examine t…
  pubmed Wang S, Wu Y, Jia H, Xu J 等 2026 Aug 25 置信度 0.82
• Exploring the potential mechanisms of Tangzukang Ointment against diabetic foot ulcers based on network pharmacology prediction and molecular docking approach.
  Tangzukang Ointment (T-Ointment) is formulated by adding ingredients such as Astragalus, Angelica sinensis, Cinnamomi Cortex, and Coix seed to the traditional formula ErMiao Pill. This ointment has the effects of clearing heat and removing dampness, warming th…
  pubmed Tang S, Zhu L, Wu X, Zhu J 等 2026 Aug 18 置信度 0.82
• Total glucosides of paeony ameliorate cognitive impairment by promoting ketogenesis and modulating Glu-AMPAR signaling.
  Impaired cerebral energy metabolism and synaptic dysfunction are closely associated with cognitive decline in Alzheimer's disease (AD). Although total glucosides of paeony (TGP) have demonstrated neuroprotective properties, whether TGP protects synaptic functi…
  pubmed Hu G, Gong S, Yan S, Rong L 等 2026 Aug 25 置信度 0.82
• Non-coding RNAs in pancreatitis: from mechanisms to therapeutics.
  Pancreatitis is a complex inflammatory condition of the pancreas and can be classified into acute pancreatitis (AP) and chronic pancreatitis (CP). The pathogenesis of the disease remains unclear, and effective preventive or therapeutic strategies are currently…
  pubmed Du Z, Shao W, Ou C, Zhang W 等 2026 Aug 25 置信度 0.82
• eIF3A Promotes the Warburg Effect in Cervical Cancer through m(6)A-dependent Translational Regulation of ENO1.
  Eukaryotic translation initiation factors (eIFs) play a crucial role in tumor progression; however, which eIFs are most significant in cervical cancer (CC) remains unclear. In this study, eIF3A and eIF4E were found to be highly expressed in CC and associated w…
  pubmed Cai L, Jiang Y, Gu L, Li F 等 2026 Aug 17 置信度 0.82
• IBRV induces mitochondrial apoptosis via the ER-mitochondrial calcium axis mediated by unfolded protein response in MDBK cells.
  Infectious bovine rhinotracheitis virus (IBRV), also known as bovine herpesvirus 1 (BoHV-1), is a globally important pathogen causing severe cattle diseases and substantial economic losses. However, the molecular mechanism by which IBRV induces host cell apopt…
  pubmed Wei Y, Wang X, Kou W, Yu W 等 2026 Aug 25 置信度 0.82
• The letter to editor regarding "Association of NRF-2 changes in plasma and pericardial fluid with renal injury in patients undergoing cardiac surgery".
  pubmed Chen J 2026 置信度 0.82
• DangGuiSiNi Decoction and QiShenYiQi Pills Ameliorate Hyperpermeability and Edema Induced by Cold Exposure.
  Limb frostbite caused by cold exposure is a prevalent injury in winter. However, effective therapies remain limited, particularly for cold-induced edema. This study evaluated the therapeutic potential of DangGuiSiNi Decoction (DSD), QiShenYiQi Pills (QSYQ), an…
  pubmed Li H, Chen FK, Li AQ, Weng DZ 等 2026 Aug 置信度 0.82
• Chemical ingredients and molecular mechanisms underlying Yiqi Xingnao oral liquid in alleviating cerebral ischemic stroke based on UHPLC-Q-TOF-MS/MS and integrated network pharmacology.
  Ischemic stroke is a worldwide problem associated with substantial morbidity, disability and mortality. Yiqi Xingnao oral liquid (YQXN), derived from Buyanghuanwu Decoction, is clinically effective but mechanistically unclear. This study aimed to identify bloo…
  pubmed Huang W, Leng F, Wang C, Gao J 等 2026 Aug 3 置信度 0.82
• Ferroptosis: significance to zoonotic diseases and therapeutic prospects.
  Ferroptosis is a distinct modality of programmed cell death driven by iron-dependent lipid peroxidation, exerting a pivotal regulatory influence on the infection dynamics and immune responses associated with zoonoses. This article systematically elucidates the…
  pubmed Tian L, Cheng X, Ni J, Yang R 等 2026 Dec 置信度 0.82