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SHR-A2102 is a new antibody-drug conjugate consisting of a fully human nectin-4-directed monoclonal antibody bound to a topoisomerase I inhibitor payload via a cleavable linker. We did a phase 1 trial to evaluate the safety, preliminary activity, and pharmacok…
pubmed
Zhong R, Hong H, Yan M, Wang Q 等
2026 Sep
置信度 0.82
-
Impaired efferocytosis is a key driver of plaque instability during atherosclerosis progression. Efficient clearance of apoptotic cells through efferocytosis relies on the coordinated action of multiple regulatory factors.
pubmed
Zhao Y, Wu K, Wang H, Cheng X 等
2026 Aug 22
置信度 0.82
-
Burning mouth syndrome (BMS), a heterogeneous idiopathic orofacial pain disorder mainly affecting postmenopausal females, is frequently accompanied by anxiety and sleep disturbances. Existing BMS molecular studies have focused primarily on oral bacterial DNA, …
pubmed
Lu D, Su Z, Wen N, Wang J 等
2026
置信度 0.82
-
Medicinal plants have been used for thousands of years across various cultures as a natural Source of healing and health maintenance. These plants contain bioactive compounds—such As alkaloids, flavonoids, glycosides, tannins, and essential oils—that can be us…
datacite
Parikshit D. Shirure*, Sneha V. Jadhav, Nandini B. Bajaj, Supriya Y. Ingale, Shraddha K. Birajdar, Abhishek R. Bansode
2026
置信度 0.66
-
Medicinal plants have been used for thousands of years across various cultures as a natural Source of healing and health maintenance. These plants contain bioactive compounds—such As alkaloids, flavonoids, glycosides, tannins, and essential oils—that can be us…
datacite
Parikshit D. Shirure*, Sneha V. Jadhav, Nandini B. Bajaj, Supriya Y. Ingale, Shraddha K. Birajdar, Abhishek R. Bansode
2026
置信度 0.66
-
A review of the research literature indicated that Chinese and Vietnamese immigrants to Australia (and the US) have a poor understanding of the risks for viral hepatitis transmission, hepatitis vaccines and treatments, and little knowledge of the relationship …
datacite
Hopwood, MN, Treloar, C
2013
置信度 0.66
-
Ginkgo biloba, one of the oldest tree species and is also known as the “living fossil”, it has been used in traditional medicine in Asia, Europe, Cannada, Brazil and the Americas for thousands of years. Its diverse phytochemical profile, mostly consisting of t…
datacite
Bina Suaihiamchung Riamei1*, Abishkar Rai1, Thupten Tsering Khochilu1, Miss. Kanchan Singh2
2026
置信度 0.66
-
Ginkgo biloba, one of the oldest tree species and is also known as the “living fossil”, it has been used in traditional medicine in Asia, Europe, Cannada, Brazil and the Americas for thousands of years. Its diverse phytochemical profile, mostly consisting of t…
datacite
Bina Suaihiamchung Riamei1*, Abishkar Rai1, Thupten Tsering Khochilu1, Miss. Kanchan Singh2
2026
置信度 0.66
-
TCM-Meridian (杏林經緯) is a physician-supervised, multi-agent AI workbench for Traditional Chinese Medicine. A ReAct main agent orchestrates specialised sub-agents (record writing, hallucination review, information collection, low-confidence annotation, note comp…
datacite
Hsieh, Hong-Wen
2026
置信度 0.66
traditional chinese medicinemulti-agent systemretrieval-augmented generationclinical decision supportlarge language models
-
TCM-Meridian (杏林經緯) is a physician-supervised, multi-agent AI workbench for Traditional Chinese Medicine. A ReAct main agent orchestrates specialised sub-agents (record writing, hallucination review, information collection, low-confidence annotation, note comp…
datacite
Hsieh, Hong-Wen
2026
置信度 0.66
traditional chinese medicinemulti-agent systemretrieval-augmented generationclinical decision supportlarge language models
-
The convergence of Artificial Intelligence (AI) and Network Pharmacology (NP) has emerged as a transformative paradigm in the rational discovery of poly-herbal medicines. Traditional herbal formulations, characterized by multi-component and multi-target pharma…
datacite
Sadiya Prabin*1, K. Hamsika Sri2, Edalada Pavan Kumar3, Gurleen Kaur4, Dr. Md Sayeed Anwar5
2026
置信度 0.66
Network Pharmacology; Poly-herbal Drug Discovery; Artificial Intelligence; Machine Learning; Graph Neural Networks; Traditional Chinese Medicine; Ayurveda; Multi-target Pharmacology; Drug-Target Interaction; Phytochemoinformatics
-
The convergence of Artificial Intelligence (AI) and Network Pharmacology (NP) has emerged as a transformative paradigm in the rational discovery of poly-herbal medicines. Traditional herbal formulations, characterized by multi-component and multi-target pharma…
datacite
Sadiya Prabin*1, K. Hamsika Sri2, Edalada Pavan Kumar3, Gurleen Kaur4, Dr. Md Sayeed Anwar5
2026
置信度 0.66
Network Pharmacology; Poly-herbal Drug Discovery; Artificial Intelligence; Machine Learning; Graph Neural Networks; Traditional Chinese Medicine; Ayurveda; Multi-target Pharmacology; Drug-Target Interaction; Phytochemoinformatics
-
Icariin, a prenylated flavonol from Epimedium species, demonstrates dual action on FGFR3 signaling through direct receptor antagonism and downstream MAPK pathway modulation. Chinese studies show icariin promotes chondrocyte proliferation via ERK1/2 activation …
datacite
MedicOath Autonomous Discovery Engine
2026
置信度 0.66
Achondroplasiadrug repurposingMedicOathtraditional_medicine
-
Icariin, a prenylated flavonol from Epimedium species, demonstrates dual action on FGFR3 signaling through direct receptor antagonism and downstream MAPK pathway modulation. Chinese studies show icariin promotes chondrocyte proliferation via ERK1/2 activation …
datacite
MedicOath Autonomous Discovery Engine
2026
置信度 0.66
Achondroplasiadrug repurposingMedicOathtraditional_medicine
-
Source code, tests, environment locks and reproducibility workflow for an entity-, lineage-, dependence- and calibration-aware audit of TCM Transcriptomic Atlas v6. Both prespecified inferential methods failed the mandatory calibration gate; the released analy…
datacite
Fan, Gaojun, Ma, Yan, Wang, Xiaoyun
2026
置信度 0.66
transcriptomicsdata provenanceshared controlssampling covariancesimulation-based calibration
-
Source code, tests, environment locks and reproducibility workflow for an entity-, lineage-, dependence- and calibration-aware audit of TCM Transcriptomic Atlas v6. Both prespecified inferential methods failed the mandatory calibration gate; the released analy…
datacite
Fan, Gaojun, Ma, Yan, Wang, Xiaoyun
2026
置信度 0.66
transcriptomicsdata provenanceshared controlssampling covariancesimulation-based calibration
-
Salvianolic acids from Danshen (Salvia miltiorrhiza) and hydroxysafflor yellow A from Honghua (Carthamus tinctorius) synergistically activate HIF-1α, upregulating VEGFA and promoting angiogenesis while enhancing alternative glucose metabolism through PDK1 inhi…
datacite
MedicOath Autonomous Discovery Engine
2026
置信度 0.66
Glycogen storage disease due to aldolase A deficiencydrug repurposingMedicOathtraditional_medicine
-
Salvianolic acids from Danshen (Salvia miltiorrhiza) and hydroxysafflor yellow A from Honghua (Carthamus tinctorius) synergistically activate HIF-1α, upregulating VEGFA and promoting angiogenesis while enhancing alternative glucose metabolism through PDK1 inhi…
datacite
MedicOath Autonomous Discovery Engine
2026
置信度 0.66
Glycogen storage disease due to aldolase A deficiencydrug repurposingMedicOathtraditional_medicine
-
TCM-Meridian (杏林經緯) is a physician-supervised, multi-agent AI workbench for Traditional Chinese Medicine. A ReAct main agent orchestrates specialised sub-agents (record writing, hallucination review, information collection, low-confidence annotation, note comp…
datacite
Hsieh, Hong-Wen
2026
置信度 0.66
traditional chinese medicinemulti-agent systemretrieval-augmented generationclinical decision supportlarge language models
-
TCM-Meridian (杏林經緯) is a physician-supervised, multi-agent AI workbench for Traditional Chinese Medicine. A ReAct main agent orchestrates specialised sub-agents (record writing, hallucination review, information collection, low-confidence annotation, note comp…
datacite
Hsieh, Hong-Wen
2026
置信度 0.66
traditional chinese medicinemulti-agent systemretrieval-augmented generationclinical decision supportlarge language models
-
TCM-Meridian (杏林經緯) is a physician-supervised, multi-agent AI workbench for Traditional Chinese Medicine. A ReAct main agent orchestrates specialised sub-agents (record writing, hallucination review, information collection, low-confidence annotation, note comp…
datacite
Hsieh, Hong-Wen
2026
置信度 0.66
traditional chinese medicinemulti-agent systemretrieval-augmented generationclinical decision supportlarge language models
-
TCM-Meridian (杏林經緯) is a physician-supervised, multi-agent AI workbench for Traditional Chinese Medicine. A ReAct main agent orchestrates specialised sub-agents (record writing, hallucination review, information collection, low-confidence annotation, note comp…
datacite
Hsieh, Hong-Wen
2026
置信度 0.66
traditional chinese medicinemulti-agent systemretrieval-augmented generationclinical decision supportlarge language models
-
datacite
Jiang, Nanfei
2026
置信度 0.66
-
datacite
Jiang, Nanfei
2026
置信度 0.66
-
Andrographis paniculata, commonly known as Kalmegh or the “King of Bitters,” is a well-known medicinal herb widely used in Ayurveda, Siddha, Unani, and Traditional Chinese Medicine. The plant contains several bioactive constituents, among which andrographolide…
datacite
Avinash kumar*
2026
置信度 0.66
Andrographis paniculata, andrographolide, hepatoprotective, phytochemistry, pharmacology, herbal medicine
-
Andrographis paniculata, commonly known as Kalmegh or the “King of Bitters,” is a well-known medicinal herb widely used in Ayurveda, Siddha, Unani, and Traditional Chinese Medicine. The plant contains several bioactive constituents, among which andrographolide…
datacite
Avinash kumar*
2026
置信度 0.66
Andrographis paniculata, andrographolide, hepatoprotective, phytochemistry, pharmacology, herbal medicine
-
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Ming-xi Zou
2021-12-17T16:24:58Z
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Lin Yu, DuJiang Yang, Zhijun Ye, GuoYou Wang
2026-02-25T03:42:11Z
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Traditional Chinese Medicine focuses on TCM’s historical roots, influential figures in the field, and development and global influence. This book is part of the Chinese Civilisation series which seeks to inform, inspire and ignite curiosity about one of the wo…
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Xu Erping
2026-07-27T04:15:07Z
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Imaging studies after acupuncture at acupoints and sham acupoints have shown significant changes in the function of specific parts of the brain, but these findings are not consistent. In this meta-analysis, we examined different studies to determine whether th…
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Chen C, Chen Z, Liu A, Zhang Q 等
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Nie Lifang
2008-05-22T12:53:21Z
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Xie Zhufan
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Ka-Wai Fan
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5-Fluorouracil (5-Fu) is a chemotherapeutic agent widely used to treat various cancers, which causes intestinal mucositis as a common side effect. Ginsenoside Rc, an active compound with anti-inflammatory, antioxidant, immunomodulatory, and antitumor propertie…
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Liyue Xu, Xiaolan Zhao, Fei Tang, Jingnan Zhang 等
2024-12-05T08:33:51Z
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2012-07-18T22:36:48Z
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2025-10-26T00:58:44Z
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Chengwei He
2018-05-24T02:03:29Z
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crossref
YanBin WU, Chao ZHANG, XiuCai ZHANG, JianGuo WU 等
2017-10-26T08:50:27Z
置信度 0.70
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Abstract Background Mesenchymal stem cell (MSC) senescence limits their therapeutic potential. Adipose-derived stem cells (ADSCs), though easily accessible, are prone to senescence under oxidative or inflammatory stress. Ginsenoside Rg1, with antioxidant and a…
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Yuan Fang, Chenghong Mou, Xinlang Yu, Jiakang Zhang 等
2026-01-27T14:17:20Z
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Yongyan Wang
2019-09-13T01:59:53Z
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2014-06-17T14:11:29Z
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Background Despite many studies on polymer-incorporated nanocarriers for ophthalmic drug delivery, few have thoroughly explored the relationship between coating composition and performance. This study aimed to evaluate the effects of three commonly used cation…
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Jing Zhang, Min Zha, Anping Wan, Satya Siva Kishan Yalamarty 等
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B Xu
2016-09-09T20:23:09Z
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Cerebral ischemia is a series of harmful reactions, such as acute necrosis of tissue, inflammation, apoptosis, autophagy, and blood-brain barrier injury, due to the insufficient blood supply to the brain. Inflammatory response and gut microbiota imbalance are …
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Ke Fu, Dewei Zhang, Yinglian Song, Min Xu 等
2021-11-11T20:50:07Z
置信度 0.70
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Abstract Clinical practice guideline adaptation is critical for standardizing care, yet existing frameworks like the ADAPTE process lack specificity for Traditional Chinese Medicine (TCM), whose principles diverge fundamentally from western medicine. To addres…
crossref
Xiuli Xie, Yangyang Wang, Heba Hussein, Hui Li 等
2026-01-20T09:34:09Z
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Background and Aims. Several components of Cayratia japonica (CJ) such as rutin and quercetin have shown anti-inflammatory effect, yet its function in ulcerative colitis (UC) remains to be clarified. This study focuses on the modulatory effect of CJ on UC as w…
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Jun Sun, Ping Zhao, Xufeng Ding, Fang Li 等
2022-12-30T15:05:05Z
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Objective . This study adopts the method of retrospective analysis to collect general information and laboratory results of physical examination population, hoping to clarify the correlation between uric acid and thyroid hormone. Methods . The subjects of the …
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Guanqun Chao, Yue Zhu, Lizheng Fang
2019-07-07T19:31:58Z
置信度 0.70
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Although bone marrow mesenchymal stem cells (BMMSCs) are effective in treating chronic bacterial prostatitis (CBP), the homing of BMMSCs seems to require ultrasound induction. Dihydroartemisinin (DHA) is an important derivative of artemisinin (ART) and has bee…
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Shen Li, Yongzhang Li, Xiaozhe Su, Aiyun Han 等
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2023-06-01T03:14:15Z
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Xiaoyu Hu, Yang Zhang, Guo Chen, Yibei Li 等
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Yufeng Zhao, Qi Xie, Liyun He, Baoyan Liu 等
2015-05-12T13:16:10Z
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Li Qiang, Liu Zhibin, Yang Jiping, Guo Huijun 等
2016-06-10T22:40:18Z
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The gut microbiota is the largest symbiotic ecosystem with the host and has been proven to play an important role in maintaining the stability of the intestinal environment. The imbalance of the gut microbiota is caused by the imbalance between the symbiotic m…
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Qihong Liu, Yunfeng Luo, Xiao Ke
2022-11-15T22:05:07Z
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Background. Curcumin, a polyphenolic constituent from Curcuma longa, possesses antioxidant, hypolipidemic, and antidiabetic properties and has been reported to protect against diabetic kidney disease (DKD); however, the effect is inconsistent. Objective. This …
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Zhao Jie, Mo Chao, Ai Jun, Shi Wei 等
2021-12-02T14:07:06Z
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2021-12-07T03:16:10Z
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2021-12-07T01:50:05Z
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Jia Lingyan, Li Yibei, Hu Xiaoyu, Lin Wu 等
2016-05-31T20:15:19Z
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Cui Yinglin, Zheng Weifeng, Xu Li, Meng Yi 等
2016-11-09T23:45:25Z
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Zhaohui Wu, Huajun Chen, Xiaohong Jiang
2012-07-07T05:00:45Z
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Yin Chen, Halmurat Upur, Meizuo Zhong, Renaguli Aizezi
2014-08-09T18:30:48Z
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Background and objective: The diagnosis and treatment of other common and chronic diseases under circumstances of COVID-19 epidemic is very serious. This study aimed to summarize and assess the social effects and potential value of combination of Internet hosp…
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Chao Huang, Weixuan Huang, Haosheng Liu, Zhaoxin Chen 等
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Qu Liuxin, Xing Liyang, Wanda Norman, Li Mingju 等
2017-03-18T23:45:44Z
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Er-Xin Yu
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Stewart Geary
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2020-10-19T15:06:34Z
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Polydatin, one of the natural active small molecules, was commonly applied in protecting and treating liver disorders in preclinical studies. Oxidative stress plays vital roles in liver injury caused by various factors, such as alcohol, viral infections, dieta…
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Dandan Tang, Qing Zhang, Huxinyue Duan, Xun Ye 等
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Shaoping Li
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He Kuanqi
2008-06-19T08:43:01Z
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Horses with behavioral abnormalities may injure themselves or their handlers, display aggression towards humans and other horses and disrupt the human-horse relationship. These behaviors are precipitated by stressful events, such as frightening experiences, ch…
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Emily Mangan
2023-07-10T14:49:29Z
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Review question / Objective: In order to verify effectiveness and safety of traditional Chinese medicine in the treatment of pediatric adenoid hypertrophy. Condition being studied: Pediatric adenoid hypertrophy. A total of 135 potential literatures were select…
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menghui liu, yanchao zhang, lixin li
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Y.G. Wang, H.C. Xu, J. Feng, C.Y. Xu 等
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Mehran Mirabzadeh, Zahra Sahraee, Roja Rahimi
2013-09-12T01:49:29Z
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Abstract Background This paper reports a case of chronic dacryocystitis due to nasal stones. Case presentation An 84-year-old male patient was admitted to the hospital with chronic dacryocystitis of the right eye due to tearing and purulent discharge from the …
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Yandi Huo, Luoxiang Li, Ya Mo, Sirui Guo
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Background: Acute pancreatitis (AP) is characterized by the abnormal activation of pancreatic enzymes due to various causes, leading to local pancreatic inflammation. This can trigger systemic inflammatory response syndrome and multi-organ dysfunction. Hyperli…
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