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This study investigates how the interaction between gene expression time delay and domain size governs spatio-temporal pattern formation in a reaction-diffusion system. To investigate these phenomena, we utilize a modified version of the Schnakenberg model cal…
pubmed
Das N, Balázs I, Das B, Röst G
2026 Jun 11
置信度 0.82
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Cryopreservation is the storage of biological materials like cells, tissues, or even organs at cryogenic temperatures. This technology is a key enabler for biobanking, reproductive medicine, and cell therapy, and is positioned as a vital part of the future of …
pubmed
Wilczok D, Valdés-Hernández J, Bernales V, Aspuru-Guzik A 等
2026 Jul
置信度 0.82
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Acinetobacter baumannii is the major cause of healthcare-associated infections attributed to its remarkable ability to resist multiple antibiotics. The study aimed to characterize the clinical A. baumannii isolates, evaluate their antibiotic resistance pattern…
pubmed
Alruwaili M, Malik F, Khan Z, Munir M 等
2026 Jun 10
置信度 0.82
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Brucellosis is a globally important zoonotic disease caused by Brucella melitensis, the most virulent and clinically significant species affecting both humans and livestock. Unlike many Gram-negative pathogens, B. melitensis lacks conventional virulence factor…
pubmed
Kapoor J, Panda A, Rajagopal R, Kumar S 等
2026 Aug 10
置信度 0.82
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Iron accumulation in the substantia nigra (SN) is a hallmark of Parkinson's disease (PD). Quantitative susceptibility mapping (QSM) including source separation can generate maps of total susceptibility χ, paramagnetic or positive susceptibility [Formula:…
pubmed
Zhang C, Sisman M, Zhang Q, Skudin C 等
2026 Jun 10
置信度 0.82
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The legume family originated ca. 60-65 million years ago and soon diversified into at least six lineages (now extant subfamilies). The signal of whole genome duplications (WGD) is apparent in species sampled from all six subfamilies. The early diversification …
pubmed
Lee HO, Stai JS, Xu Q, Hewavithana T 等
2026 Jun
置信度 0.82
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Effective prevention of drowning and aquatic incidents requires timely and accurate surveillance supported by high-quality validated data. In Denmark, the use of the free-text fields in the Danish Prehospital Medical Record has proven effective in identifying …
pubmed
Ostenfeldt CK, Breindahl N, Graff C, Kragholm KH 等
2026 Jun 9
置信度 0.82
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In this study, multifunctional polymer-stabilized CuO-ZnO hybrid nanocomplexes were developed through a green synthesis approach and systematically evaluated for their antimicrobial and protein delivery potential. Bimetallic CuO-ZnO nanoparticles were biosynth…
pubmed
Isiksel E, Attar A, Aktaş E, Altikatoglu Yapaoz M
2026 Jun 9
置信度 0.82
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In primates, primary visual cortex (V1) circuits support early visual processing, whereas in the lateral prefrontal cortex (LPFC), they support higher-order computations. Here, we characterized the intrinsic electrophysiological (e)-properties and morphology o…
pubmed
Feyerabend M, Pommer S, Mestern S, Jimenez-Sosa MS 等
2026 Jun 9
置信度 0.82
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The human microbiota plays a pivotal role in health, with widespread alterations implicated in conditions ranging from inflammatory disorders to cancer. While correlation-based network analyses have illuminated ecological interactions within these communities,…
pubmed
Iacovacci J, Cannon N, McCulloch JA, Rancati T 等
2026 Jul 21
置信度 0.82
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Intestinal parasitic infections (IPIs) remain a significant public health challenge across Ethiopia, including the Tigray region, where school-age children (SAC) are particularly vulnerable. The La'elay Maichew district, characterized by rural agrarian and irr…
pubmed
Abrha Yanshet T, Gebrezgabiher G, Birmeka M
2026 Jun
置信度 0.82
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Platelets, a crucial source of liquid biopsy samples, play a significant role in the progression of various malignancies, including non-small cell lung cancer (NSCLC). However, specific biomarkers for early-stage NSCLC have not yet been identified. In this stu…
pubmed
Xu Z, Li W, Yu Y, Wu H 等
2026 Jun 8
置信度 0.82
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Sequence-to-function (S2F) models can evaluate arbitrary DNA sequences, yet they struggle to fully capture inter-individual variation in gene expression. We introduce SAGE-net, a scalable framework for training and evaluating S2F models using personal genomes.…
pubmed
Spiro AE, Tu X, Sheng Y, Sasse A 等
2026 Jul
置信度 0.82
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Targeted therapies such as small-molecule inhibitors act by blocking proteins essential for cancer cell survival, yet omics-based modeling of drug sensitivity often lacks mechanistic grounding. We present FORGE (Factorization Of Response and Gene Essentiality)…
pubmed
Bhattacharjee N, Peela SCM, Halder A, Mathew B 等
2026 Jun 8
置信度 0.82
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Shimajiri et al. (Nature, 2024, 634, 347-351) reported for the first time on direct evidence for a carbon-carbon one-electron σ bond in a recently synthesized stable radical cation. Single-crystal X-ray diffraction analysis, electron density maps, and RA…
pubmed
Zazza C, Grandinetti F, Sanna N, Borocci S 等
2026 Jun
置信度 0.82
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Quadrupedal animals like mice navigate their environments through complex coordination of neural signals and biomechanical movements, enabling stable and directed locomotion. While many computational models simplify this process by assuming left-right symmetri…
pubmed
Molkov YI, Mohammed MAY, Stell T, Harralson A 等
2026
置信度 0.82
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Since RSV vaccine licensure in 2023, vaccine effectiveness (VE) studies demonstrated first season protection against severe RSV disease including RSV-related hospitalization/emergency department (ED) visits. Here, we estimate VE over two seasons, by RSV subtyp…
pubmed
Tartof SY, Aliabadi N, Zasowski E, Goodwin G 等
2026 Aug
置信度 0.82
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In nations with developing healthcare infrastructures, the dual burden of Type 2 diabetes mellitus (T2DM) and tuberculosis represents a critical health challenge. The aim of this study is to investigate the influence of T2DM on the development of multidrug-res…
pubmed
Seid A, Nureddin S
2026
置信度 0.82
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Although effective teamwork and communication are critical to surgical safety, structured training for non-technical skills (NTS) remains limited compared with technical simulation. The ACS/APDS Phase III Team-Based Skills Curriculum calls for scalable tools t…
pubmed
Barker J, Demirel D, Jackson C, Johansson A 等
2026
置信度 0.82
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Chronic diseases remain leading contributors to global mortality, yet digital biomarkers offer transformative potential for personalized management. This systematic review evaluates the clinical performance of digital biomarkers across multiple chronic disease…
pubmed
Manikandan S, Shore S, Waszczuk D, Miriyala S 等
2026 Jun
置信度 0.82
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The atlantoaxial lateral mass joint is a pivotal structure facilitating cervical rotation and flexion-extension. Its morphological characteristics are intrinsically linked to degenerative pathologies and segmental instability. However, comprehensive three-dime…
pubmed
Zhang T, Zhang J, Sun M, Li X 等
2026 Jun 7
置信度 0.82
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Estimation of accurate genetic parameters require using all data that were available upon selection. Existing methods for parameter estimation become impractical with large genomic data, and estimation becomes complex if parameters vary over time. This study a…
pubmed
Gowane G, Hidalgo J, Hollifield MK, Misztal I 等
2026 Jun 7
置信度 0.82
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Metastatic hormone-sensitive prostate cancer (mHSPC) with limited metastatic burden presents a therapeutic challenge, with residual PSMA-avid disease post-androgen receptor pathway inhibitor (ARPI) treatment poorly characterized in prospective studies.
pubmed
Pan J, Wang B, Zhu B, Gan H 等
2026 Sep
置信度 0.82
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Gout, a painful inflammatory arthritis, is characterized by hyperuricemia and monosodium urate crystal deposition, with growing evidence linking its pathogenesis to gut microbiome dysbiosis. However, traditional diversity metrics fail to capture the complex sp…
pubmed
Zhou J, Qiao Y, Chen H, Li L 等
2026 Jun 7
置信度 0.82
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Understanding plant adaptation is critical under intensifying global aridification. Succulence, a key drought-resistance innovation, has evolved repeatedly across plant lineages, yet its intrinsic genomic drivers remain underexplored. Integrating comprehensive…
pubmed
Yu J, Zhou J, Luo S, Leitch IJ 等
2026 Jun 8
置信度 0.82
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Microneedle arrays (MNAs) is a rapidly emerging technology with broad biomedical applications in drug delivery and biosensing. With sub-millimeter dimensions and periodicity, MNAs possess geometries nearly ideal for biomedical devices operating within the tera…
pubmed
Lee SH, Jung HJ, Kim J, Park BC 等
2026 Aug
置信度 0.82
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Little is known about predictors of response to radionuclide therapy with PSMA-ligands in patients with [ 18 F]FDG-positive metastatic castration-resistant prostate cancer (mCRPC). We assessed the correlation between baseline characteristics, including dual tr…
pubmed
Santo G, di Santo G, Kronthaler A, Farsad M 等
2026 Sep
置信度 0.82
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Salivary gland tumors are rare and morphologically diverse, posing both diagnostic and scientific challenges. This study presents the first phase of the SALV-Dataset Registry; a nationwide, expertly curated, and fully digitized clinicopathological resource, de…
pubmed
Burghout KST, Weijer JAJ, Evers AC, Breimer GE 等
2026 Jun 5
置信度 0.82
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To compare the measurement results of different instrumental color analysis methods with a reference spectrophotometer.
pubmed
Türkoğlu Tarı E, Bayraktar Y
2026 Jun
置信度 0.82
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BACKGROUNDWith a notification rate of 44.9 per million population in 2024, Belgium was among the countries with the highest measles rate of the European Union/European Economic Area countries. Although the coverage of the first dose of measles-mumps-rubella (M…
pubmed
Kremer C, Hammami N, Cornelissen L, Theeten H 等
2026 Jun
置信度 0.82
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Transplantation of adipose-derived mesenchymal stromal cells (ASCs) or their insulin-producing derivatives holds promise for diabetes mellitus therapy due to their regenerative properties. However, the harsh microenvironment in type 2 diabetes (T2D) likely imp…
pubmed
Zeinhom A, Mohamed AY, Abdel-Aziz NN, Sayed Diab M 等
2026 Aug
置信度 0.82
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The prognostic relevance of the detection mode for regional lymph node recurrence (LNR) remains unclear. We aimed to identify the risk factors associated with isolated regional LNR and to evaluate the impact of the mode of detection on distant metastasis-free …
pubmed
Kim MK, Kim SW, Ahn JH, Kim H 等
2026 Jun 4
置信度 0.82
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Keratinocyte stem cells are essential for maintaining epidermal homeostasis and enabling efficient tissue repair. Regulation of their self-renewal and differentiation is critical, as its disruption can impair regeneration and drive pathological conditions such…
pubmed
Dam B, Ajnabi J, Saha T, Shrivastava A 等
2026 Jun 3
置信度 0.82
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Neurons in basolateral amygdala (BLA) encode positive and negative valence. However, many additional variables must be represented to describe all aspects of emotional states. To investigate how BLA encodes these states, we presented mice with conditioned stim…
pubmed
O'Neill PK, Posani L, Meszaros J, Warren P 等
2026 Jul
置信度 0.82
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Epigenetic modifications have been linked to atherosclerotic cardiovascular disease and could constitute therapeutic targets.
pubmed
Ingold M, Müller C, Krolevets M, Yapıcı E 等
2026 Jul 21
置信度 0.82
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Insect declines have been recorded in many parts of the world, however, the vast majority of taxa and ecosystems, particularly in the tropics, remain poorly documented. Monitoring insects in the tropics is challenging due to their immense diversity, and the li…
pubmed
Szczygieł HA, Quitmeyer A, Johns B, Dent DH 等
2026 Jan 12
置信度 0.82
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This paper offers a methodological critique of the study by AlShurman et al. that examined whether COVID-19 vaccine hesitancy (VH) and COVID-19-related factors interact to influence booster dose uptake among university students in Canada from a syndemic perspe…
pubmed
Yu T, Yuan J, Wang L, Li M
2026 Dec
置信度 0.82
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Climate-driven temporal shifts in seasonal environments are altering some of the environmental cues that organisms use to time reproduction, potentially leading to trophic mismatches across ecosystems. In the Arctic, marine predators must balance conditions at…
pubmed
Syposz M, Varpe Ø, Descamps S, Fort J 等
2026 Jul
置信度 0.82
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Gut dysbiosis is widely recognized as a contributor to autoimmune diseases, as it can lead to the expression of microbial antigens that disrupt immune regulation through specific molecular mechanisms. However, existing resources do not systematically link gut …
pubmed
Hashmi L, Rehman SU, Jabeen F, Kayani MUR
2026 Jan 15
置信度 0.82
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Optogenetics employs light to regulate neuronal activity with exceptional spatiotemporal precision, thereby enabling the direct modulation of learning and memory processes in the human brain. This capability to externally control neuronal signaling via optical…
pubmed
Lee J, Kim G, Lee D, Son S 等
2026 Jul
置信度 0.82
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Human single-strand-selective monofunctional uracil DNA glycosylase 1 (hSMUG1) removes uracil, 5-hydroxymethyluracil (5hmU) and 5-fluorouracil (5FU) from DNA, thereby initiating the base excision repair (BER) process. hSMUG1 is important for maintaining genomi…
pubmed
Ludäscher JM, Scaletti Hutchinson E, Vila-Julià G, Jemth AS 等
2026 Jun 2
置信度 0.82
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Enteric infectious diseases claim more than 1 million lives annually and are among the top ten causes of death in children younger than 5 years. Remarkable global investment has been dedicated to enteric infectious disease prevention and control; however, the …
pubmed
GBD 2023 Diarrhoeal Disease and Enteric Infectious Diseases Collaborators
2026 Jun 2
置信度 0.82
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Routine surveillance through the health management information system (HMIS), has taken a de facto management structure centered on district leadership, aided by the district health information software for reporting. System performance and credibility has lon…
pubmed
Kigozi SP, Okiring J, Kigozi LS, Emuron P 等
2026 Jun 1
置信度 0.82
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Caveolae are invaginated plasma membrane nanodomains traditionally associated with membrane trafficking and signalling. These multifunctional organelles are also essential mechanosensors mediating the cell response to mechanical stress. We investigated the rol…
pubmed
Mani SK, Tardif N, Rossier O, Khater IM 等
2026 Jun
置信度 0.82
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This study investigated the effects of different brewing conditions on the sensory and chemical properties of Turkish black tea and examined the relationships among the related parameters. The brewing variables evaluated were teapot type, brewing method, teapo…
pubmed
Cho JM, Abanoz YY, Boyraz A, Demir A 等
2026 Jun 1
置信度 0.82
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The aim of this study was to evaluate roots and root canal morphology of mandibular first and second permanent molars in a Tunisian population using cone-beam computed tomography (CBCT), providing detailed anatomical data to support clinical endodontic practic…
pubmed
Ben Hadj Khalifa A, Ayari G, Abidi M, Moalla H 等
2026 Feb 1
置信度 0.82
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Cancer is a multifaceted disease that places a significant burden on healthcare systems and economies, driving the urgent need for novel therapeutic agents to curb its prevalence and impact. Thirty-three analogues of N-substituted-7-and 8-methyl-4-hydroxy-2-qu…
pubmed
Al-Lahowani B, Aswad TA, Hajjo R, Islim RA 等
2026 Jun
置信度 0.82
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Protoporphyrinogen IX oxidase (PPO, EC 1.3.3.4) is an important target for the development of highly efficient and environmentally friendly herbicides. Unfortunately, conventional N-phenylphthalimide-derived PPO inhibitors are often plagued by limited herbicid…
pubmed
Geng W, Zhao R, Zhang W, Yang J 等
2026 Sep
置信度 0.82
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Metabolomics software development has accelerated rapidly, yet no recent systematic analysis has quantified how the landscape is evolving across computational methods, geographies, and the research community's technology adoption. There is a strong need within…
pubmed
Domingo-Fernández D, Healey D, Kind T, Allen A 等
2026 Jul 14
置信度 0.82
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Soybean (Glycine max (L.) Merr.) is one of the important legume crops, rich in protein, vegetable oil, maintain soil fertility and used as human food and livestock feed. Despite its importance, adoption and productivity of soybean in South Ethiopia is limited …
pubmed
Dalo DD, Andeta AF, Mamo BG, Gunnabo AH
2026 May 30
置信度 0.82
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Spatial properties of subcellular calcium handling in cardiac myocytes underpin both normal and abnormal functions. The structure and density of the transverse and axial tubular system (t-system) strongly determine the spatiotemporal synchrony of calcium-induc…
pubmed
Colman MA, Shiferaw Y, Conesa D
2026 May 30
置信度 0.82
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This prospective study aimed to comparatively investigate the effects of conventional mandibular anaesthesia and digital mandibular and intraosseous anaesthesia administered using the computer-assisted local anaesthesia device (SleeperOne 5) on pain and anxiet…
pubmed
Dogan S, Sahin M, Balci S
2026 May 30
置信度 0.82
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The Derivation Path: From Book 1 to Book 2, Thermal Reduction to PNBA, and the Discovery of Identity Physics at the Sovereign Anchor Architect: HIGHTISTIC (Russell Trent) Coordinate: [9,9,8,1] · Origins Series · Paper 1 Corpus dependencies: [9,9,0,0] · [9,9,3,…
datacite
Trent, Russell
2026
置信度 0.66
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The Derivation Path: From Book 1 to Book 2, Thermal Reduction to PNBA, and the Discovery of Identity Physics at the Sovereign Anchor Architect: HIGHTISTIC (Russell Trent) Coordinate: [9,9,8,1] · Origins Series · Paper 1 Corpus dependencies: [9,9,0,0] · [9,9,3,…
datacite
Trent, Russell
2026
置信度 0.66
-
Long-term monitoring programs are crucial to assess trends in biodiversity, and so make informed decisions for conservation and resource management. However, disregarding the statistical power of a monitoring program can lead to incorrect conclusions about spe…
datacite
Menon, Vishnu, Southwell, Darren, Robley, Alan, Rees, Matthew 等
2026
置信度 0.66
FOS: Biological scienceslong-term monitoringthreatened speciesinvasive predatorred fox
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ORGANOID INTELLIGENCE LAW: LEGAL FRAMEWORKS FOR BIOLOGICAL COMPUTING AND NEURO-ETHICAL GOVERNANCEDOI: 10.5281/zenodo.20547234 AUTHORED BY:Mohamed Kamal Arafa ElrakhawiLegal Researcher, International Consultant, Jurist, Author, and International Lecturer in Law…
datacite
elrakhawi, mohamed kamal arafa
2026
置信度 0.66
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ORGANOID INTELLIGENCE LAW: LEGAL FRAMEWORKS FOR BIOLOGICAL COMPUTING AND NEURO-ETHICAL GOVERNANCEDOI: 10.5281/zenodo.20547234 AUTHORED BY:Mohamed Kamal Arafa ElrakhawiLegal Researcher, International Consultant, Jurist, Author, and International Lecturer in Law…
datacite
elrakhawi, mohamed kamal arafa
2026
置信度 0.66
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Abstract The integration of 6G technology into the Industrial Internet of Things (IIoT) promises to redefine manufacturing through "Hyper-Reliable Low-Latency Communication" (HRLLC). However, the deployment of complex Machine Learning (ML) models at the edge r…
datacite
Seema Patil, Harshavardhana Doddamani, Savitha A C, Julianne Rivers
2026
置信度 0.66
6G Networks, Industrial IoT (IIoT), Edge Intelligence, Deep Reinforcement Learning, Latency Optimization
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Abstract The integration of 6G technology into the Industrial Internet of Things (IIoT) promises to redefine manufacturing through "Hyper-Reliable Low-Latency Communication" (HRLLC). However, the deployment of complex Machine Learning (ML) models at the edge r…
datacite
Seema Patil, Harshavardhana Doddamani, Savitha A C, Julianne Rivers
2026
置信度 0.66
6G Networks, Industrial IoT (IIoT), Edge Intelligence, Deep Reinforcement Learning, Latency Optimization
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