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• Faster, Smarter, Precise: Integrating Speed Breeding and CRISPR-Based New Genomic Techniques into the Conventional Cereal Breeding Pipeline
  preprints 2026 置信度 0.74
• Development of a CRISPR/Cas9-mediated transformation procedure for the wheat pathogen <i>Zymoseptoria tritici</i>
  preprints 2026 置信度 0.74
• Shining stars: Transgenesis and efficient metamorphosis in the sea star <i>Patiria miniata</i>
  preprints 2026 置信度 0.74
• A Dual-Locus-Targeting Strategy to Enhance CRISPR/Cas9-mediated CFTR Replacement via Helper-Dependent Adenoviral vector in porcine genome
  preprints 2026 置信度 0.74
• Metformin modulates autophagy in heterozygous and CRISPR-edited <i>TSC2</i> primary fibroblasts
  preprints 2026 置信度 0.74
• One-step generation of mice by Transposon-Enhanced Multi-Plex Orchestration Editing(TEMPO-Editing)
  preprints 2026 置信度 0.74
• Targeted genome editing of the non-model cyanobacterium <i>Cyanothece</i> PCC 7425 via CRISPR/Cas12a
  preprints 2026 置信度 0.74
•  A Versatile Genetic Toolkit for the Deep-Sea Fungus Penicillium janthinellum SH0301
  preprints 2026 置信度 0.74
• Sequentially Self-Assembled Supramolecular Nanocomplexes Enable Systemic Cas9 RNP Delivery and In Vivo Tumor Genome Editing
  preprints 2026 置信度 0.74
• CRISPR/Cas9-mediated deletion of Shp1 and Shp2 reveals distinct roles in human megakaryopoiesis and proplatelet formation
  preprints 2026 置信度 0.74
• Systematic Development of a Compact Genome-Editing Tool Leveraging the TAM-Independent DNA Nuclease TasR in <i>Bacillus subtilis</i>
  preprints 2026 置信度 0.74
• Nuclear shuttling of donor DNA via sgRNA recognition sequences drives CRISPR/Cas9 gene targeting efficiency
  preprints 2026 置信度 0.74
• TAMIPAMI: Software and methods for PAM/TAM identification in CRISPR and OMEGA gene editing systems
  preprints 2026 置信度 0.74
• Development of a CRISPR-Cas9-Based Cellular Model for SGCB Gene Mutation: A Platform for Investigating Gene Therapy Strategies in LGMD2E
  preprints 2026 置信度 0.74
• CRISPR/Cas9-targeted mutagenesis of tobacco DMR6 homeologs reduces seedling susceptibility to Phytophthora nicotianae race 0
  preprints 2026 置信度 0.74
• CRISPR-mediated engineering of bovine satellite cells for Alpha-Gal Syndrome-compatible cultivated meat
  preprints 2026 置信度 0.74
• Increasing the shelf life of tomato fruit by editing the β-D-N-acetylhexosaminidase (β-hex) gene using CRISPR/Cas9 technology
  preprints 2026 置信度 0.74
• Building Gene Editing Platforms for Personalized Medicine: The Next Step in Interventional Genetics
  preprints 2026 置信度 0.74
• From Editing Genes to Orchestrating Networks: CRISPR and the Future of Precision Oncology
  preprints 2026 置信度 0.74
• Rational and computation-assisted engineering of a compact and efficient StaCas9 genome editor
  preprints 2026 置信度 0.74
• Multiplex Genome Editing Overcomes Photoperiod Sensitivity in Tropical Maize
  preprints 2026 置信度 0.74
• Programmable RNA targeting with clustered regularly interspaced short palindromic repeats (CRISPR) effector Cas7-11 in zebrafish embryos and mammalian cells
  preprints 2026 置信度 0.74
• Intranasal CRISPR- lipid nanoparticles targeting MAPK9 reduce neuroinflammation after traumatic brain injury
  preprints 2026 置信度 0.74
• EasyCAPS: A web tool for restriction-based genotyping and rational CRISPR-Cas9 donor design
  preprints 2026 置信度 0.74
• Transposon end recognition and pairing by I-F3 CRISPR-associated transposase
  preprints 2026 置信度 0.74
• All-in-one, Cas13d-based cell-specific gene knockdown system for zebrafish
  preprints 2026 置信度 0.74
• In Vivo Safety Evaluation of Silver Nanoparticle Encapsulated CRISPR/Cas9: Implications for HIV Gene Therapy
  preprints 2026 置信度 0.74
• South American <i>Plasmodium falciparum</i> isolates reveal new insights into the role of PfAAT1 in mediating resistance to Chloroquine
  preprints 2026 置信度 0.74
• Reprogramming Cas9 PAM Recognition for Allele-Specific Editing
  preprints 2026 置信度 0.74
• Parallel Activation and Interference CRISPR (PAIR) with Sequencing Uncovers DNA Repair Networks Guiding Precision Cell Engineering
  preprints 2026 置信度 0.74
• Complete POR ablation in human adrenal cells reveals steroidogenic rerouting and variant-dependent loss of cytochrome P450 support
  preprints 2026 置信度 0.74
• Designing Fidelity of CRISPR-Cas Endonucleases by Kinetic Insights
  preprints 2026 置信度 0.74
• Advances in CRISPR Plant Applications
  preprints 2026 置信度 0.74
• PrEditR: A protein-centric platform for CRISPR-mediated base editor sgRNA design
  preprints 2026 置信度 0.74
• Intranasal CRISPR- lipid nanoparticles targeting MAPK9 reduce neuroinflammation after traumatic brain injury
  preprints 2026 置信度 0.74
• Machine Learning-Based Prediction of Base Editor sgRNA fitness score
  preprints 2026 置信度 0.74
• Allele-specific correction of dominant Best vitelliform macular dystrophy in patient-derived retinal pigment epithelium
  preprints 2026 置信度 0.74
• Structure-guided discovery and engineering of miniature CRISPR-Cas12m for epigenome editing
  preprints 2026 置信度 0.74
• Endogenous intronic RNA tightly controls Cas9/CRISPR-mediated gene editing in human cells
  preprints 2026 置信度 0.74
• Exploiting HSD17B11-dependent dialkynylcarbinols cytotoxicity for facile CRISPR/Cas9-based gene inactivation
  preprints 2026 置信度 0.74
• CRISPR-Mediated Linearization of IDLV Donor Enables Precise Targeted Integration in Human Hematopoietic Stem Cells
  preprints 2026 置信度 0.74
• Quantum-Inspired CRISPR-Nano Platforms for Host-Directed Therapy: A Conceptual Framework for Infectious Disease Applications
  preprints 2026 置信度 0.74
• Intersectional CRISPR-Cas9 genetic targeting reveals acute role of Na _V 1.1 in proprioceptive behavior and function
  preprints 2026 置信度 0.74
• RNA Therapeutics Targeting Skeletal Muscle: Emerging Antisense and Gene-Modifying Strategies
  preprints 2026 置信度 0.74
• Development of efficient methods for protoplast-to-plant regeneration in coffee and successful CRISPR-Cas9 editing in protoplasts
  preprints 2026 置信度 0.74
• Cas9/sgRNA-mediated genome editing of citrus via mature tissue transformation enables both high-efficacy genome editing and early flowering
  preprints 2026 置信度 0.74
• Multiple approaches for CRISPR-based targeting of DNA methylation to promoters of bacterial and viral susceptibility genes in cassava
  preprints 2026 置信度 0.74
• Gene Therapy for β-Haemoglobinopathies: From Molecular Correction to Curative Medicine
  preprints 2026 置信度 0.74
• A nuclear targeting approach enables efficient transgenesis in the milkweed bug <i>Oncopeltus fasciatus</i>
  preprints 2026 置信度 0.74
• A novel polymerase III promoter for gene editing in the agricultural pest <i>Ceratitis capitata</i>
  preprints 2026 置信度 0.74
• PALINCODE: Recording cell lineage with ternary palindromic CRISPR bits
  preprints 2026 置信度 0.74
• Genome editing of marsupial <i>RSX</i> reveals conserved and divergent principles in mammalian X-inactivation
  preprints 2026 置信度 0.74
• Sequentially Self-Assembled Supramolecular Nanocomplexes Enable Systemic Cas9 RNP Delivery and <i>In Vivo</i> Tumor Genome Editing
  preprints 2026 置信度 0.74
• Computational analysis of GC content distribution and editing performance in TP53-targeted CRISPR gRNA design
  preprints 2026 置信度 0.74
• Virus-like particle delivery enables orthogonal genome editing <i>in vitro</i> and <i>in vivo</i>
  preprints 2026 置信度 0.74
• A Streamlined Protocol for Small-scale Protoplast Generation and CRISPR/Cpf1-mediated Genome Editing in <i>Fusarium oxysporum</i>
  preprints 2026 置信度 0.74
• Dissecting multi-gene virulence phenotypes with base editing requires consideration of target-independent mutagenesis
  preprints 2026 置信度 0.74
• Target site and guide RNA multiplexing architecture shape homing gene drive efficiency in <i>Drosophila suzukii</i>
  europepmc 2026 置信度 0.80
• Insights into the genetic architecture of resistance to viral haemorrhagic septicaemia virus in rainbow trout from a genome-wide association study to <i>in vitro</i> CRISPR-Cas9 functional evaluation
  preprints 2026 置信度 0.74
• Cell-type targeted CRISPR/Cas9 Clock knockdown in mouse VTA dopamine neurons alter sleep, behavior, and cellular excitability
  preprints 2026 置信度 0.74
• SiFEA4 encoding the bZIP transcription factor regulates panicle architecture in foxtail millet (Setaria italica)
  preprints 2026 置信度 0.74
• Integrated CRISPR-Cas9 and 3D Bioprinting Approach for Development and Evaluation of High-Throughput Advanced Organotypic Cancer Models
  preprints 2026 置信度 0.74
• Atypical MDM2 p53 Regulation and Chemosensitivity Induced by Proximal PAS Deletion
  preprints 2026 置信度 0.74
• Protocol for Non-viral HDR-based CRISPR/Cas9 platform for small custom editing in primary T cells
  preprints 2026 置信度 0.74
• Genome sequence and efficient CRISPR/Cas9 gene editing in the solanacea specialist pest <i>Tetranychus evansi</i>
  preprints 2026 置信度 0.74
• Virus-Like Particles: The Next Frontier in Livestock Gene Editing
  preprints 2026 置信度 0.74
• Public Knowledge, Attitudes, and Ethical Views on CRISPR-Cas 9 in Taif, Saudi Arabia
  europepmc 2026 置信度 0.80
• Targeted Epigenetic Modulation Outperforms Nuclease- and Deaminase-Based Editing for Durable <i>Pcsk9</i> Silencing in a Clinically Relevant Delivery System
  preprints 2026 置信度 0.74
• VigExp: A functionally verified platform for aiding cowpea ( <i>Vigna unguiculata</i> ) and related legume crop improvement
  preprints 2026 置信度 0.74
• Host-Informed Engineering of Glycosylation in Komagataella phaffii for Human Biantennary N-Linked Glycans
  preprints 2026 置信度 0.74
• Short single-stranded DNA oligonucleotides enable intracellular transcription of functional RNAs in mammalian cells
  preprints 2026 置信度 0.74
• Orthosteric and allosteric effects of anti-CRISPR II-C1 inhibition on <i>Geo</i> Cas9 from integrated structural biophysics
  preprints 2026 置信度 0.74
• Study design and rationale of Boxed-Breathing-Heart: a translational ex vivo study evaluating virus-mediated gene delivery for gene therapy in normothermic machine-perfused human hearts
  preprints 2026 置信度 0.74
• Successful gene editing in tetraploid alfalfa using the open-source, AI-derived OpenCRISPR-1
  preprints 2026 置信度 0.74
• First report of genetic transformation and CRISPR/Cas12a-mediated gene editing of European beech ( <i>Fagus sylvatica</i> L.) employing a transient protoplast system
  preprints 2026 置信度 0.74
• CRISPR-Cas9 and PiggyBac Mediated Genetic Modification of Sand Fly Vectors Targeting Olfactory and Non-Lethal Phenotypic Genes
  preprints 2026 置信度 0.74
• CRISPR-Cas9-induced genetic mosaicism in three species of the microcrustacean <i>Daphnia</i>
  preprints 2026 置信度 0.74
• StickForStats: automated statistical assumption validation for reproducible computational biology
  preprints 2026 置信度 0.74
• Rational design of synthetic proteins using a genome-scale CRISPR screen
  preprints 2026 置信度 0.74
• Context-dependent crosstalk between DNA methylation and histone modifications shapes durable CRISPR/dCas9-based epigenetic editing
  preprints 2026 置信度 0.74
• Programmable CRISPRtune dissects the transcriptional repressive activity of MeCP2
  preprints 2026 置信度 0.74
• Ai-driven Personalized Leukemia Therapy Integrating CRISPR Nanoparticle Delivery and Car-t Immunotherapy: A Cfd-based Analysis Using Ansys Fluent
  preprints 2026 置信度 0.74
• ALPINE: A Scalable Pipeline for Comprehensive Classification of Gene-Editing Outcomes from Long-Read Amplicon Sequencing
  preprints 2026 置信度 0.74
• Gene Editing Strategies for Neurological and Mental Disorders: Advances in Delivery, Methodology, and Clinical Translation
  preprints 2026 置信度 0.74
• CRISPR-mediated functional mapping of <i>IL2RG</i> variants in primary human T cells predicts X-linked severe combined immunodeficiency
  preprints 2026 置信度 0.74
• Novel mouse reporter models for the detection of genome editing events in vivo
  preprints 2026 置信度 0.74
• Dual Knockout of <i>StAMY23</i> and <i>StVINV</i> Improves Postharvest Storage Traits in Potato
  preprints 2026 置信度 0.74
• Cloning and functional verification of endogenous U6 promoters for developing an efficient CRISPR/Cas9-mediated genome editing system in kenaf (Hibiscus cannabinus L.)
  preprints 2026 置信度 0.74
• Editing of Photoperiod Response Genes Enables Rapid Adaptation of Tropical Maize to Long-day Environments
  preprints 2026 置信度 0.74
• From Gene Editing to Environmental Cleanup: Bridging Advanced rDNA and Biotechnology with Bioremediation and Bioethical Governance: A Review
  preprints 2026 置信度 0.74
• A Modality-Aware CRISPR Actionability Framework for Functional Prioritization of Genome-Wide Significant Type 2 Diabetes Loci
  preprints 2026 置信度 0.74
• Next-generation all-in-one CRISPR/Cas9 multiply-edited CD30CAR-T cells: Potency despite risk of translocations
  preprints 2026 置信度 0.74
• Modulation of the sensitivity to ruxolitinib-mediated JAK2 inhibition by mutationally activated SHP2 exhibits cell context dependency in pre-clinical models of myeloproliferative neoplasms
  preprints 2026 置信度 0.74
• Transposable element disruption of a second thyroglobulin-like gene confers Vip3Aa resistance in <i>Helicoverpa armigera</i>
  preprints 2026 置信度 0.74
• Multiplex Gene Editing and Effect Analysis of Yield, Fragrance, and Blast Resistance Genes in Rice
  preprints 2025 置信度 0.74
• Reverse genetics in humanized mice reveals CARD8-mediated pyroptosis causing pancytopenia in human DPP9 deficiency
  preprints 2026 置信度 0.74
• Genome editing of key domestication genes overcomes self-incompatibility and bitter taste in cultivated buckwheat
  preprints 2026 置信度 0.74
• MDA5 and the integrated stress response control sex-specific type 1 diabetes onset in NOD mice
  preprints 2026 置信度 0.74
• A universal platform for simultaneous TCRα/β removal enables safer and more potent TCR therapies and autoimmune modeling
  preprints 2026 置信度 0.74
• Hierarchical Interplay between H3K27ac and H3K4me3 in Transcriptional Regulation
  preprints 2026 置信度 0.74