基因技术工具 · 全部实体（第 29 / 100 页）

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• In-Depth Characterization of Stem Cell Potency and Genotoxicity for Clinical-Scale Ex Vivo CRISPR/Cas9 Gene Editing
  preprints 2026 置信度 0.74
• Striatal FOXP2 is essential for stable vocal production in non-human primates
  preprints 2026 置信度 0.74
• NF1 deficiency induces metabolic reprogramming and epithelial-mesenchymal transition in glioblastoma
  preprints 2026 置信度 0.74
• CRISPR-Cas9 editing of grapevine clade V-related <i>mlo</i> genes revealed new insights into the contribution of each <i>mlo</i> gene to grapevine powdery mildew resistance ( <i>Erysiphe necator</i> ) and plant development
  preprints 2026 置信度 0.74
• CRISPR-DA: Adapting CRISPR gRNA design for detection assays
  preprints 2025 置信度 0.74
• Developing a Molecular Toolkit to ENABLE all to apply CRISPR/Cas9-based Gene Editing <i>in planta</i>
  preprints 2025 置信度 0.74
• Establishment of Stable Immortalized Human Choroidal Melanocytes for Ocular Research
  preprints 2026 置信度 0.74
• Single-cell CRISPR activation screens in primary B cells discover gene regulatory mechanisms for hundreds of autoimmune risk loci
  preprints 2026 置信度 0.74
• Defining a Midgestational Window for <i>In Utero</i> Genome Editing of the Fetal Murine Cortex
  preprints 2026 置信度 0.74
• Septins regulate cytokinesis and multicellular development in the closest living relatives of animals
  preprints 2026 置信度 0.74
• Engineered Allosteric Control Enhances Specificity and Potency of CRISPR-CasX-based Epigenetic Repressors
  preprints 2026 置信度 0.74
• Gene editing without a genome: generation and validation of F0 CRISPR mutants in gastropod mollusc <i>Crepidula fornicata</i>
  preprints 2025 置信度 0.74
• LEMONmethyl-seq: Targeted long-read DNA methylation profiling reveals dynamics of CRISPR epigenome editing and endogenous DNA methylation patterns
  preprints 2026 置信度 0.74
• CRISPR/Cas9-mutagenesis reveals that varying dependence on HSF1 is associated with differences in coral heat tolerance
  preprints 2026 置信度 0.74
• Octopaminergic signaling contributes to thermal adaptation to elevation in African honey bees ( <i>Apis mellifera</i> )
  preprints 2026 置信度 0.74
• Chemical control of 2'-hydroxyl-dependent Cas9 target engagement enables CRISPR RNA ribose replacement
  preprints 2026 置信度 0.74
• <i>ST3GAL3</i> loss-of-function disrupts synaptic integrity and excitatory/inhibitory cortical dynamics
  preprints 2026 置信度 0.74
• Targeted Gene and Genome Editing Strategies for Epilepsy: Advances and Translational Challenges
  preprints 2026 置信度 0.74
• Enhancing CRISPR Education: A Plug-And-Play Framework for Teaching Gene Editing in Plant Biology
  preprints 2025 置信度 0.74
• Loss of <i>PAX4</i> results in disrupted endocrine pancreas development and neonatal diabetes in pigs
  preprints 2026 置信度 0.74
• Circuit-specific gene editing for precision modulation of neuronal activity with CRISPR-rabies virus
  preprints 2025 置信度 0.74
• Complete Genomic Ablation of Cytochrome P450 Oxidoreductase Unveils Endogenous Steroidogenic Shunting and Variant Instability
  preprints 2026 置信度 0.74
• CRISPR-Cas9 Mediated Knockout of LacZ Gene in Escherichia Coli for Enhanced Production of Asparaginase
  preprints 2025 置信度 0.74
• Next-generation all-in-one CRISPR/Cas9 multiply-edited CD30CAR-T cells: Potency despite risk of translocations
  preprints 2026 置信度 0.74
• Exploring the Efficiency of Multi-Target Editing with Single Base Editors in Haematopoietic Cell lines
  preprints 2026 置信度 0.74
• A Unique Phage DUF669 Protein mediates Post-cleavage Repair Against Host CRISPR Immunity
  preprints 2026 置信度 0.74
• Gene Targeted Therapies for Neurodegenerative Disorders: Strategies and Implications in ALS and SMA
  preprints 2026 置信度 0.74
• WAVE2 and REST/NRSF Regulate Clustered Gene Expression by Maintaining Heterochromatin Organization
  preprints 2026 置信度 0.74
• CRISPR Precision Meets Self-Powered Bioelectronics in Spinal Cord Recovery: Design Principles, Safety and Regulatory Pathways
  preprints 2026 置信度 0.74
• Synthetic gRNA-mediated multiplex CRISPR enables the generation of translucent F0 Xenopus laevis for in vivo imaging
  preprints 2026 置信度 0.74
• Identification a Compact Promoter using a New Promoter Selection Strategy and Engineering Hybrid Pol II/III Enable Efficient Genome Editing in Human Retinal Ganglion Cells
  preprints 2026 置信度 0.74
• CRISPR/Cas9-Mediated Siprolamin mutagenesis increase the content of functional amino acids in foxtail millet (Setaria italica)
  preprints 2025 置信度 0.74
• Direct detection of CRISPR mutations and transcriptional responses at single cell resolution <i>in vivo</i>
  preprints 2025 置信度 0.74
• <i>Lmna</i> deficiency promotes EPHX2 nuclear translocation to ameliorate cardiac dysfunction in mice
  preprints 2026 置信度 0.74
• From Editing Genes to Orchestrating Networks: CRISPR and the Future of Precision Oncology
  preprints 2025 置信度 0.74
• SPIC-dependent erythrophagocytic macrophages drive granuloma formation and pathogen persistence during intracellular bacterial infection
  preprints 2026 置信度 0.74
• Generation of GJB2 Gene-Edited Porcine Embryos as a Model for Human Congenital Deafness via CRISPR/Cas9 and Cytosine base editors
  preprints 2025 置信度 0.74
• Loss of FANCM impairs primordial germ cell differentiation <i>in vitro</i>
  preprints 2026 置信度 0.74
• CROP: A feature-independent context-aware method for CRISPR-Cas9 frameshift prediction
  preprints 2026 置信度 0.74
• Integrating CRISPR Technologies and Artificial Intelligence to Predict and Modulate Host-Microbe Interactions
  preprints 2025 置信度 0.74
• Neuron-specific epigenetic repression of <i>Cdk5</i> impairs hippocampal-dependent memory in male and female mice
  preprints 2026 置信度 0.74
• pGGTOX: a versatile plasmid platform for recombination-based genome editing across <i>Enterobacteriaceae</i>
  preprints 2025 置信度 0.74
• Repeated mutation of a GT92 glycosyltransferase gene confers antiviral resistance in two <i>Caenorhabditis</i> species
  preprints 2026 置信度 0.74
• A proteome-wide association study of cardiovascular diseases in 640,000 participants of multiple ancestries
  preprints 2026 置信度 0.74
• AAV-delivered CRISPR-Cas9 elicits persistent retinal immune responses compared with transient responses to RNP
  preprints 2025 置信度 0.74
• Virus-like particles enable targeted gene engineering and pooled CRISPR screening in primary human myeloid cells
  preprints 2025 置信度 0.74
• Loss of expression of the E3 ligase and tumour suppressor FBW7 attenuates vitamin D signaling
  preprints 2026 置信度 0.74
• Whole genome screening defines a key role of autophagy in resistance of bovine cells to BVDV infection
  preprints 2026 置信度 0.74
• β-Nicotinamide mononucleotide: a novel broad-spectrum CRISPR inhibitor
  preprints 2025 置信度 0.74
• Dissecting circadian clock machinery by genome-editing in the cricket Gryllus bimaculatus
  preprints 2026 置信度 0.74
• Engineered hematopoietic stem cells give rise to therapeutic antibody secreting B cells
  preprints 2026 置信度 0.74
• Plasmids weaponize conjugation to eliminate non-permissive recipients
  preprints 2026 置信度 0.74
• Decision letter for "Gene Therapy and Gene Editing in Type 1 Diabetes: CRISPR-Based β-Cell Replacement and Treg Immune Modulation Approaches"
  crossref 2026-04-23T21:11:07Z 置信度 0.70
• CRISPR-Cas Systems in the Diagnosis of Infectious and Non-Infectious Diseases
  crossref Aarif Ali, Javeed Iqbal Ahmad Bhat, Farheen Shafique 2025-07-04T10:41:22Z 置信度 0.70
• Tailoring Bacterial Cellulose through the CRISPR/Cas9-Mediated Gene Editing Tool in Komagataeibacter xylinus
  crossref 2025-03-18T08:20:27Z 置信度 0.70
• Tailoring Bacterial Cellulose through the CRISPR/Cas9-Mediated Gene Editing Tool in Komagataeibacter xylinus
  crossref 2025-03-18T08:20:27Z 置信度 0.70
• CRISPR-Based RNA Editing Systems (Cas13 and Cas7-11) in Plants
  crossref Vijay Sheri, Baohong Zhang 2025-05-22T07:43:58Z 置信度 0.70
• Decision letter for "Gene Therapy and Gene Editing in Type 1 Diabetes: CRISPR-Based β-Cell Replacement and Treg Immune Modulation Approaches"
  crossref 2026-04-23T21:11:07Z 置信度 0.70
• Doubts raised about CRISPR gene-editing study in human embryos
  crossref Ewen Callaway 2017-08-31T19:56:11Z 置信度 0.70
• A Technique for Gene Editing in Natural Killer Cells Using CRISPR Cas9
  crossref 2024-05-31T20:05:46Z 置信度 0.70
• A Technique for Gene Editing in Natural Killer Cells Using CRISPR Cas9
  crossref 2024-05-31T20:08:33Z 置信度 0.70
• Gene Editing and Genetic Disorders: Ethical and Legal Concerns
  crossref Vicente Beliver, Federico de Montalvo 2021-12-15T16:42:46Z 置信度 0.70
• Heparin Specifically Inhibits CRISPR/Cas12 Activation Enabling Ultrasensitive Heparin Detection and Gene Editing Regulation
  crossref 2024-02-22T12:00:14Z 置信度 0.70
• Molecular Surgery: Regulating mRNA-CRISPR Gene Editing as a Procedure, Not a Product
  In February 2025, a six-month-old infant became the first person to receive a personalized CRISPR gene-editing therapy, demonstrating both what is possible and what is missing. Current US regulatory infrastructure treats every personalized gene-editing therapy…
  crossref Jeff Coller, Sadik H. Kassim 2026-07-29T13:52:04Z 置信度 0.70
• 1. Targeting a Single Gene: Huntington’s Disease
  crossref 2019-10-15T09:05:01Z 置信度 0.70
• In Vivo Editing of the Adult Mouse Liver Using CRISPR/Cas9 and Hydrodynamic Tail Vein Injection
  crossref Francesco Niola, Frederik Dagnæs-Hansen, Morten Frödin 2019-03-25T09:03:05Z 置信度 0.70
• A Nanoimprinted Photothermal Chip for On-Demand Spatiotemporal Activation of CRISPR/Cas9 Gene Editing
  crossref 2025-12-23T10:01:07Z 置信度 0.70
• Decision letter for "Application of CRISPR/Cas9 gene editing technique in the study of cancer treatment"
  crossref 2019-06-25T13:25:55Z 置信度 0.70
• Breaching Barriers in Gene Editing: Getting CRISPR/Cas9 Ribonucleoproteins into the Cell with Cell Penetrating Peptides
  The CRISPR/Cas system is a powerful tool for both scientific research and potential therapeutic strategies for inherited diseases. This PhD thesis investigated the feasibility of cell-penetrating peptide-mediated direct delivery of CRISPR/Cas components to ach…
  crossref Mert Öktem 2024-08-21T19:14:24Z 置信度 0.70
• Editing the Genome of Human Induced Pluripotent Stem Cells Using CRISPR/Cas9 Ribonucleoprotein Complexes
  crossref Michaela Bruntraeger, Meg Byrne, Kathleen Long, Andrew R. Bassett 2019-03-25T09:03:05Z 置信度 0.70
• Tailoring Bacterial Cellulose through the CRISPR/Cas9-Mediated Gene Editing Tool in Komagataeibacter xylinus
  crossref 2025-03-18T08:20:27Z 置信度 0.70
• Principles and Practices of CRISPR-Cas9 Genome Editing Techniques
  crossref Seher Yerlikaya, Abdullah Aydın, Nisa Nur Yılmaz, Bayram Ali Yerlikaya 等 2026-04-01T14:14:25Z 置信度 0.70
• CRISPR/Cas9-based gene-editing technology for sickle cell disease
  crossref Liangliang Ma, Shanglun Yang, Qianya Peng, Jingping Zhang 等 2023-05-12T11:29:17Z 置信度 0.70
• Gene editing at CRISPR speed
  crossref 2014-04-08T19:44:10Z 置信度 0.70
• Exploring the potential of genome editing CRISPR-Cas9 technology
  crossref Vijai Singh, Darren Braddick, Pawan Kumar Dhar 2016-11-08T22:45:23Z 置信度 0.70
• CRISPR-Based Gene Editing
  crossref Shakeel Ahmad, Asif Ali Khan, Muhammad Arshad Javed 2025-04-01T15:32:44Z 置信度 0.70
• Visual Assay for Gene Editing Using a CRISPR/Cas9 System in Carrot Cells
  crossref Magdalena Klimek-Chodacka, Tomasz Oleszkiewicz, Rafal Baranski 2019-01-04T17:14:42Z 置信度 0.70
• Regulation and Governance of Gene Editing Technologies (CRISPR, etc.)
  crossref 2022-11-04T11:15:00Z 置信度 0.70
• CRISPR Cas9 Gene Editing for Sickle Cell Disease
  crossref Dr.Jennifer A Domm 2026-08-28T07:10:15Z 置信度 0.70
• CRISPR-Cas9 Mediated Gene Editing: A Revolution in Genome Engineering
  crossref 2020-03-03T11:57:22Z 置信度 0.70
• A Single-Chain Photoswitchable CRISPR-Cas9 Architecture for Light-Inducible Gene Editing and Transcription
  crossref 2020-04-06T09:09:12Z 置信度 0.70
• Decision letter for "Application of CRISPR/Cas9 gene editing technique in the study of cancer treatment"
  crossref 2019-06-25T13:25:55Z 置信度 0.70
• SOP002 Human pluripotent stem cell HDR-mediated gene editing using CRISPR/Cas9 and PiggyBac technology v1
  The piggyBac transposon system can be combined with CRISPR/Cas9 to efficiently perform genetic manipulations in animal models or cells lines, including stem cells, without leaving behind any accessory DNA sequences like for example it happens in the Cre system…
  crossref Patrick Ovando-Roche 2021-08-19T18:20:31Z 置信度 0.70
• Inducible CRISPR/Cas9 mediated gene editing expands the scope of clinically-relevant prostate cancer modeling in vitro
  crossref Cole Sims 2020-11-02T16:45:08Z 置信度 0.70
• A Technique for Gene Editing in Natural Killer Cells Using CRISPR Cas9
  crossref 2025-07-31T18:33:37Z 置信度 0.70
• Dual-Gene CRISPR Editing via Peptide Dendrimers Regulates Redox Balance for Diabetic Wound Repair
  crossref 2026-05-22T19:41:03Z 置信度 0.70
• Tailoring Bacterial Cellulose through the CRISPR/Cas9-Mediated Gene Editing Tool in Komagataeibacter xylinus
  crossref 2025-03-18T08:20:27Z 置信度 0.70
• Review for "Comparative transcriptome analysis and CRISPR/Cas9 gene editing reveal that E4BP4 mediates lithium upregulation of Per2 expression"
  crossref 2021-12-15T16:01:14Z 置信度 0.70
• Decomposing the “Tacit Knowledge Problem:” Codification of Knowledge and Access in CRISPR Gene-Editing
  The ability to edit genes with CRISPR has, in a few short years, been transformative to genetics, generating follow-on science such as drought-resistant crops and mosquitos that cannot carry malaria, and is widely expected to win a Nobel prize. The rush of sci…
  crossref Neil Thompson, Samantha Zyontz 2017-12-06T11:02:01Z 置信度 0.70
• Review for "Comparative transcriptome analysis and CRISPR/Cas9 gene editing reveal that E4BP4 mediates lithium upregulation of Per2 expression"
  crossref 2021-12-15T16:01:14Z 置信度 0.70
• Genome Editing
  crossref Nayla Munawar, Aftab Ahmad 2025-05-22T07:43:58Z 置信度 0.70
• CRISPR/Cas9-mediated knock-in in ebony gene using a PCR product donor template in Drosophila
  crossref Kathy Clara Bui, Daichi Kamiyama 2023-04-21T20:50:08Z 置信度 0.70
• Using CRISPR Gene Editing to Prevent Accumulation of Lipids in Hepatocytes
  CRISPR gene editing is a molecular technology that can be used to silence gene expression. In this experiment, genes that are known to play a role in lipid accumulation in hepatocytes were targeted. Specifically, levels of fatty acid transport proteins 2 and 5…
  crossref Erin Young, Cem Kuscu, Christine Watkins, Murat Dogan 2022-01-21T15:48:52Z 置信度 0.70
• Genome Editing in Mice
  crossref Lisbeth Ahm Hansen, Ernst-Martin Füchtbauer 2019-03-25T13:03:05Z 置信度 0.70
• CRISPR Gene Editing
  crossref 2019-03-25T09:03:05Z 置信度 0.70
• CRISPR-gRNA Design
  crossref Maria Pallarès Masmitjà, Nastassia Knödlseder, Marc Güell 2019-03-25T09:03:05Z 置信度 0.70
• New Editing Tools for Gene Therapy in Inherited Retinal Dystrophies
  Inherited retinal dystrophies (IRDs) are a heterogeneous group of diseases that affect more than 2 million people worldwide. Gene therapy (GT) has emerged as an exciting treatment modality with the potential to provide long-term benefit to patients. Today, gen…
  crossref Juliette Pulman, José-Alain Sahel, Deniz Dalkara 2022-05-04T10:50:27Z 置信度 0.70
• Application and Challenges of CRISPR/Cas9 System for Gene Editing
  crossref Thanaporn Sriyakul, Saquib Ahmed, Bhupinder Singh, Anjali Raghav 2026-06-05T11:29:32Z 置信度 0.70
• Potato Genome Editing: Recent Challenges and a Practical Procedure
  crossref Hiroaki Kusano, Ami Takeuchi, Hiroaki Shimada 2024-03-18T08:02:35Z 置信度 0.70
• Ethical Issues in Genome Editing
  crossref Huma Hameed, Muhammad Zaman, Saleha Faheem, Mahtab Ahmad Khan 等 2025-07-04T10:41:22Z 置信度 0.70