-
crossref
Paulo A. Zaini
2026-08-28T13:27:27Z
置信度 0.70
-
crossref
Paola Vagni, Naïg Chenais
2020-02-19T12:28:53Z
置信度 0.70
-
crossref
Asher Boorstein
2023-12-10T00:20:59Z
置信度 0.70
-
crossref
Tracy Hampton
2020-04-08T15:53:35Z
置信度 0.70
-
crossref
Dipankar Sardar, Md. Taslim Hossain
2024-05-15T17:08:01Z
置信度 0.70
-
crossref
2021-07-05T09:39:24Z
置信度 0.70
-
Citrus greening or Huanglongbing (HLB) disease is caused by the bacteria Candidatus Liberibacter spp. which is a major threat to the citrus industry worldwide. This has led to the generation of a large number of genomic databases characterizing HLB at the mole…
crossref
Cintia Sagawa
2024-01-08T15:27:58Z
置信度 0.70
-
crossref
2020-04-11T02:31:16Z
置信度 0.70
-
crossref
Muhammad Umer Masood, Abdullah Jamil, Mustabshira Ikram, Vishal Monga 等
2026-08-28T13:27:27Z
置信度 0.70
-
crossref
David Cyranoski
2019-05-21T14:51:58Z
置信度 0.70
-
crossref
Meena Barupal, Ashwani Kumar
2024-03-18T08:02:35Z
置信度 0.70
-
Abstract Functional characterization of genes in Plasmodium parasites often relies on genetic manipulations to disrupt or modify a gene-of-interest. However, these approaches are limited by the time required to generate transgenic parasites for P. falciparum a…
europepmc
Michael P. Walker, Scott E. Lindner
2018
置信度 0.80
-
Chromosomal abnormalities, some of the most prevalent genetic diseases in the world, are caused when chromosomes are present in the wrong number or configuration. Some common types include duplications (more chromosomes than normal), deletions (less chromosome…
crossref
Eric Japson
2026-01-02T20:04:52Z
置信度 0.70
-
ABSTRACT Many Candida species that cause infection have diploid genomes, and do not undergo classical meiosis. The application of CRISPR-Cas9 gene editing systems have therefore greatly facilitated the generation of gene disruptions, and the introduction of sp…
crossref
Lisa Lombardi, João Oliveira-Pacheco, Geraldine Butler
2019-02-23T15:05:24Z
置信度 0.70
-
crossref
Aditi Nag
2024-03-18T08:02:35Z
置信度 0.70
-
crossref
Tooba Mehboob, Naila Tabassam, Huma Hameed, Muhammad Zaman 等
2025-07-04T10:41:22Z
置信度 0.70
-
crossref
Gerard Mingarro, Marcel·lí del Olmo
2023-04-06T07:42:01Z
置信度 0.70
-
As one of the world's major food crops, the research and improvement of rice traits and breeding have always been a field of concern in agricultural science. Since the 20th century, the increasingly mature gene editing technology, from ZFNs technology to CRISP…
crossref
Yisheng Luo
2024-07-25T06:29:11Z
置信度 0.70
-
crossref
Gaetan Burgio
2025-08-26T01:50:51Z
置信度 0.70
-
Adaptive T cell immunotherapy holds great promise for the successful treatment of leukemia as well as other types of cancers. More recently, it was also shown to be an effective treatment option for chronic virus infections in immunosuppressed patients. Autolo…
crossref
Alaleh Rezalotfi, Lea Fritz, Reinhold Förster, Berislav Bošnjak
2022-01-12T14:10:12Z
置信度 0.70
-
crossref
Jonathan D Grinstein
2023-05-31T17:07:10Z
置信度 0.70
-
crossref
Ashwani Kumar, Yuan-Yeu Yau, Vijay Rani Kumar
2024-03-18T08:02:35Z
置信度 0.70
-
Orf is an acute and highly contracted human and animal infection caused by orf virus (ORFV), which mainly affects sheep and goats, especially young animals, who have close contact with sick animals. Clinically, in secondary infection cases of orf, opportunisti…
crossref
Yongzhong Yu, Fan Zhang, Xuyang Duan, ChaoQun Yang 等
2022-06-04T07:52:20Z
置信度 0.70
-
crossref
2025-11-30T14:42:00Z
置信度 0.70
-
In latest years, with the gradual perception of CRISPR Cas9 technology, coupled with the many advantages of the CRISPR Cas9 system, ease of development, simplicity of use, and low material prices, its mediated gene modifying has been higher used in diagnosing …
crossref
Ying Jin, Haiyi Wu, Jianzhao Liu, Guo Song
2023-04-06T02:32:16Z
置信度 0.70
-
crossref
2023-08-09T13:20:28Z
置信度 0.70
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crossref
Zhixun Su, Xiaofu Wang, Xiaoyun Chen, Lin Ding 等
2024-01-13T08:18:36Z
置信度 0.70
-
crossref
E. Deneault, L. Larocque, M. Khan, S. Al-Habyan 等
2023-05-10T14:01:16Z
置信度 0.70
-
crossref
Asha Arora
2024-03-18T08:02:35Z
置信度 0.70
-
crossref
Ram Mohan Ram Kumar
2018-02-10T06:46:35Z
置信度 0.70
-
crossref
Vida Ebrahimi, Atieh Hashemi
2020-05-26T11:34:12Z
置信度 0.70
-
*BACKGROUND* This review explores CRISPR/Cas9 gene editing, detailing its mechanism and broad applications. It covers bacterial genome modifications and significant clinical advancements, including its role in cancer immunotherapy (e.g., CAR-T cells, viral tar…
crossref
Nidhi Vadhavekar, Manu Pandya, Yuvraj sawant, Saloni Chatwani 等
2025-07-23T12:31:33Z
置信度 0.70
-
crossref
2020-08-26T08:30:23Z
置信度 0.70
-
crossref
Arcadio García-Pérez
2026-04-02T06:17:37Z
置信度 0.70
-
crossref
2024-08-27T14:40:51Z
置信度 0.70
-
Because cultivated strawberries are genetically complex, conventional breeding of strawberry can be difficult. Therefore, gene editing can be useful when developing strawberry varieties. This 3-page document discusses CRISPR gene editing in strawberry. Written…
crossref
Seonghee Lee, Cheolmin Yoo, Kevin M. Folta, Vance Whitaker
2020-09-28T13:17:33Z
置信度 0.70
-
crossref
Sami Rashid Mohammed Shibah
2026-01-28T15:08:07Z
置信度 0.70
-
crossref
Jun-Li Wang, Luo-Yu Liang, Lei Wu
2024-03-05T19:34:56Z
置信度 0.70
-
crossref
Era Chaudhary, Anchal Chaudhary, Saloni Sharma, Vandita Tiwari 等
2024-03-18T04:02:35Z
置信度 0.70
-
crossref
Veysel Süzerer, Selin Gül Ünsal, Engin Tilkat
2026-02-16T00:22:13Z
置信度 0.70
-
crossref
Patrick Harrison, Stephen Hart
2018-04-06T18:10:31Z
置信度 0.70
-
europepmc
Francoise Baylis, Marcus McLeod
2017
置信度 0.80
-
Although gene editing workflows typically consider the possibility of off-target editing, pseudogene-directed homology repair has not, to our knowledge, been reported previously. Here, we employed a CRISPR-Cas9 strategy for targeted excision of exon 2 in CD33 …
crossref
Benjamin C. Shaw, Steven Estus
2021-09-24T11:40:33Z
置信度 0.70
-
crossref
2025-07-30T15:03:29Z
置信度 0.70
-
crossref
2025-07-31T18:39:05Z
置信度 0.70
-
crossref
Rahil Shahzad, Shakra Jamil, Ghalib T G Alsubaie, Shakeel Ahmad 等
2025-04-01T15:32:44Z
置信度 0.70
-
crossref
MaryAnn Labant
2022-07-08T12:20:42Z
置信度 0.70
-
crossref
Ziheng Zhang, Ping Wang, Ji-Long Liu
2022-02-21T13:06:56Z
置信度 0.70
-
crossref
Sameen Shahid, Fidaa Asslam, Ayesha Imran
2025-04-01T15:32:44Z
置信度 0.70
-
crossref
CIHAN TASTAN- Aysegul Ates, Safak Ermertcan
2020-02-21T06:24:17Z
置信度 0.70
-
crossref
2021-11-14T01:31:36Z
置信度 0.70
-
crossref
J. Stephens, A. Barakate
2016-10-27T15:38:02Z
置信度 0.70
-
crossref
2021-11-14T01:31:38Z
置信度 0.70
-
crossref
Guohui Wan Min Wang
2013-12-26T12:41:04Z
置信度 0.70
-
What Is the Issue? The first therapeutics based on clustered regularly interspaced short palindromic repeats (CRISPR) technologies are entering the market. These gene editing technologies have the potential to change treatment paradigms and may be used to trea…
crossref
CADTH
2024-07-20T11:33:51Z
置信度 0.70
-
crossref
Abdul Basit, Syed Husne Mobarak, Tong-Xian Liu
2025-06-02T09:11:32Z
置信度 0.70
-
crossref
2021-11-14T01:31:25Z
置信度 0.70
-
β-thalassemia is a hereditary hemolytic illness where the synthesis of hemoglobin gets reduced. It mainly comes about because of mutations in the β-globin gene. In the recent few years, CRISPR gene editing technology has been brought in and used to correct the…
crossref
Keqi Zhou
2025-08-26T07:53:25Z
置信度 0.70
-
crossref
2021-11-14T01:31:33Z
置信度 0.70
-
This review examines genetic strategies for improving disease resistance, enhancing production efficiency, and reducing methane emissions. Livestock play an important role in global food security, providing essential sources of food and income for billions of …
crossref
Desmond Liu
2026-02-03T21:13:31Z
置信度 0.70
-
Genome-edited human-induced pluripotent stem cells (iPSCs) have broad applications in disease modeling, drug discovery, and regenerative medicine. Despite the development of clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 system, the ge…
crossref
Kaivalya Molugu, Namita Khajanchi, Cicera R. Lazzarotto, Shengdar Q. Tsai 等
2023-09-07T14:08:45Z
置信度 0.70
-
crossref
Diksha Gour, Asha Arora
2024-03-18T08:02:35Z
置信度 0.70
-
crossref
Jennifer Couzin-Frankel
2020-02-07T01:10:06Z
置信度 0.70
-
CRISPR/Cas9 has proved its revolutionary power in treating difficult diseases (such as HIV and cancer) with fresh horizons for precise medicine. CRISPR/Cas9 as a powerful tool are currently under investigation in the fields of HIV cure, for its ability to knoc…
crossref
Bohao Chen
2025-08-26T07:15:08Z
置信度 0.70
-
crossref
Sha Su, Yayun Zuo, Xiaohe Zhang, Chengzhi Jian 等
2022-11-21T14:25:50Z
置信度 0.70
-
crossref
Manreet Padwal
2020-01-16T21:02:54Z
置信度 0.70
-
crossref
2024-12-16T17:00:27Z
置信度 0.70
-
crossref
2021-11-14T01:31:32Z
置信度 0.70
-
crossref
Paige Charlins, Ramesh Akkina
2018-07-30T13:47:27Z
置信度 0.70
-
crossref
Yan Gong, Siyu Tian, Shubiao Zhang
2021-11-03T18:49:12Z
置信度 0.70
-
crossref
2020-02-10T12:03:07Z
置信度 0.70
-
europepmc
2024
置信度 0.80
-
europepmc
2020
置信度 0.80
-
europepmc
2021
置信度 0.80
-
europepmc
2019
置信度 0.80
-
europepmc
2019
置信度 0.80
-
europepmc
2018
置信度 0.80
-
europepmc
2020
置信度 0.80
-
europepmc
2019
置信度 0.80
-
europepmc
2020
置信度 0.80
-
europepmc
2020
置信度 0.80
-
europepmc
2019
置信度 0.80
-
europepmc
2019
置信度 0.80
-
europepmc
2019
置信度 0.80
-
europepmc
2018
置信度 0.80
-
europepmc
2017
置信度 0.80
-
europepmc
2021
置信度 0.80
-
europepmc
2016
置信度 0.80
-
europepmc
2016
置信度 0.80
-
europepmc
2018
置信度 0.80
-
europepmc
2015
置信度 0.80
-
europepmc
2015
置信度 0.80
-
europepmc
2017
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2017
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
Forest ecosystems face escalating threats from climate change alongside a surging demand for sustainable bioproducts. While conventional tree breeding is inherently constrained by long generation cycles, high heterozygosity, and complex genomes, CRISPR-based g…
pubmed
Gulfam T, Li W, Han Z, Gulfam Y 等
2026
置信度 0.82
-
europepmc
2026
置信度 0.80