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• The next frontier: autonomous, plant-based robotic astronauts for exoplanet exploration
  preprints 2025 置信度 0.74
• Evolutionary chemical learning in dimerization networks
  We present a novel framework for chemical learning based on Com- petitive Dimerization Networks (CDNs)— systems in which multiple molecular species, e.g. proteins or DNA/RNA oligomers, reversibly bind to form dimers. We show that these networks can be trained …
  preprints 2025 置信度 0.74
• Engineering C3.5 Photosynthesis: Coupling Mitochondrial Bioenergetics to Rubisco Efficiency in <i>Arabidopsis</i>
  preprints 2025 置信度 0.74
• Beyond Hunger: Structure, Signaling and Systemic Roles of Ghrelin
  preprints 2025 置信度 0.74
• One-pot cloning and protein expression platform for genetic engineering
  preprints 2025 置信度 0.74
• scYeast: a Biological-knowledge-guided Foundation Model on Yeast Single-Cell Transcriptomics
  preprints 2025 置信度 0.74
• Systematic Optimization Enables Near-Perfect In Vitro Transformation Efficiencies for <i>Spirodela polyrhiza</i> (Greater Duckweed)
  preprints 2025 置信度 0.74
• BACK MATTER
  crossref 2025-02-13T02:48:16Z 置信度 0.70
• International synthetic biology policy developments and implications for global biodiversity goals
  In December 2022, the governments of 196 countries adopted the Kunming-Montreal Global Biodiversity Framework (KMGBF), a strategic plan to support and advance implementation of the objectives of the Convention on Biological Diversity (CBD) and its subsidiary a…
  crossref Felicity Keiper, Ana Atanassova 2025-06-30T14:54:06Z 置信度 0.70
• Review for "SYNTHETIC BIOLOGY ROUTES TO NEW AND EXTINCT NATURAL PRODUCTS"
  crossref 2025-03-21T17:01:20Z 置信度 0.70
• Review for "SYNTHETIC BIOLOGY ROUTES TO NEW AND EXTINCT NATURAL PRODUCTS"
  crossref 2025-03-21T17:01:20Z 置信度 0.70
• Decision letter for "SYNTHETIC BIOLOGY ROUTES TO NEW AND EXTINCT NATURAL PRODUCTS"
  crossref 2025-03-21T17:01:20Z 置信度 0.70
• Decision letter for "SYNTHETIC BIOLOGY ROUTES TO NEW AND EXTINCT NATURAL PRODUCTS"
  crossref 2025-03-21T17:01:20Z 置信度 0.70
• A Convergence Roadmap for Computational Biology, Sustainable Agriculture, and Synthetic Biology, 2025–2045
  Biology used to be a slow science. A single experiment could take a season, a PhD, or a career. That is changing. Over the last fifteen years, biology has become a data science almost as much as a wet-lab science, and this shift is now touching medicine, farmi…
  crossref Md.Nimur Rahman Durjoy 2026-08-18T13:14:48Z 置信度 0.70
• Modular Transcriptional Regulation Using Switchable Transcription Terminators and Aptamers: Design and Optimization in Synthetic Biology
  crossref Jiayan Jiao, Minghong Shi, Shuting Zheng, Xianai Shi 等 2025-06-05T05:10:03Z 置信度 0.70
• Decision letter for "How many plasmids can bacteria carry? A synthetic biology perspective"
  crossref 2025-07-31T21:09:21Z 置信度 0.70
• Decision letter for "How many plasmids can bacteria carry? A synthetic biology perspective"
  crossref 2025-07-31T21:09:21Z 置信度 0.70
• Lab Course Projects
  crossref 2025-02-13T02:48:16Z 置信度 0.70
• Foundations of English Literary Studies
  crossref 2025-12-14T14:55:19Z 置信度 0.70
• Engineering Plasmids with Synthetic Origins of Replication
  Abstract Plasmids remain by far the most common medium for delivering engineered DNA to microorganisms. However, the reliance on natural plasmid replication mechanisms limits their tunability, compatibility, and modularity. Here we refactor the natural pMB1 or…
  crossref Baiyang Liu, Xiao Peng, Matthew R. Bennett, Matthew R. Lakin 等 2025-02-21T21:55:13Z 置信度 0.70
• Neurolinguistic Programming of Synthetic Biology Systems: A Linguistic-Driven Paradigm for Bio-Circuit Control
  crossref Kallol Chakrabarti 2025-04-09T03:59:50Z 置信度 0.70
• Review for "How many plasmids can bacteria carry? A synthetic biology perspective"
  crossref 2025-07-31T21:09:21Z 置信度 0.70
• Review for "How many plasmids can bacteria carry? A synthetic biology perspective"
  crossref 2025-07-31T21:09:21Z 置信度 0.70
• Phage-delivered CRISPRi enables bacterial biocomputation
  Charlotte Ayn Cialek; Phage-delivered CRISPRi enables bacterial biocomputation, Synthetic Biology, , ysaf013, https://doi.org/10.1093/synbio/ysaf013
  crossref Charlotte Ayn Cialek 2025-07-20T23:13:20Z 置信度 0.70
• Safety is Priority #1
  crossref 2025-02-13T02:48:16Z 置信度 0.70
• Lab Rooms and Equipment
  crossref 2025-02-13T02:48:16Z 置信度 0.70
• Synthetic ion channels made of DNA
  crossref Ran Tivony 2024-12-31T08:38:32Z 置信度 0.70
• The Japan-UK Synthetic Biology Conference, Spring 2025: Strengthening Global Links to Engineer Biology
  crossref 2025-06-20T03:43:10Z 置信度 0.70
• How many plasmids can bacteria carry? A synthetic biology perspective
  Plasmids are pinnacle tools in synthetic biology and other biotechnological applications. They serve as the simplest approach to introduce recombinant DNA, which is then transcribed into RNA that functions as is or is translated into a protein of interest. Des…
  crossref Cholpisit Kiattisewee 2025-07-29T23:06:01Z 置信度 0.70
• Membrane Topography-Driven Movement of Biomolecular Condensates
  ABSTRACT Biomolecular condensates are assemblies of proteins or nucleic acids that exhibit liquid-like properties and organize intracellular biochemical reactions within many cells. Some condensates require membrane association, and we previously developed an …
  crossref Matthias Pöllmann, Katja Zieske 2025-03-26T04:41:17Z 置信度 0.70
• Synthetic Biology Boosts the Biological Depolymerization and Upcycling of Waste Plastic Resources
  crossref Mian Wu, Junwei Zhuang, Xijing He, Feihong Zhu 等 2025-03-04T21:36:16Z 置信度 0.70
• Stanford Emerging Technology Review 2025 Chapter 2: Biotechnology or Synthetic Biology
  crossref 2025-08-06T17:21:31Z 置信度 0.70
• groovDB in 2025: A community-editable database of small molecule biosensors
  The groovDB database (https://groov.bio) was launched in 2022 with the goal of organizing information on prokaryotic ligand-inducible transcription factors (TFs). This class of proteins is important in fundamental areas of microbiology research and for biotech…
  preprints Joshua David Love, Brady Michael Rafferty, Michael Thomas, Nicole N Zhao 等 2025 置信度 0.74
• Synthetic biology design principles enable efficient bioproduction of Heparosan with low molecular weight and low polydispersion index for the biomedical industry
  Abstract Heparosan is a natural polymer with unique chemical and biological properties, that holds great promise for biomedical applications. The molecular weight (Mw) and polydispersion index (PDI) are critical factors influencing the performance of heparosan…
  crossref Yadira Boada, Marcelo Flores, Martin Stiebritz, Marco Córdova 等 2025-04-29T07:35:33Z 置信度 0.70
• Review for "Synthetic biology for heterologous expression and engineering of fungal polyketide synthases"
  crossref 2026-03-02T21:02:16Z 置信度 0.70
• Review for "Synthetic biology for heterologous expression and engineering of fungal polyketide synthases"
  crossref 2026-03-02T21:02:16Z 置信度 0.70
• Original Syn:
  crossref 2025-03-23T20:22:54Z 置信度 0.70
• Review for "Synthetic biology for heterologous expression and engineering of fungal polyketide synthases"
  crossref 2026-03-02T21:02:16Z 置信度 0.70
• Biotechnology and Synthetic Biology; Biosecurity Risk
  crossref 2025-07-24T09:52:27Z 置信度 0.70
• Genes, Chromoproteins and Antisense RNAs
  crossref 2025-02-13T02:48:16Z 置信度 0.70
• Stimuli-driven cyclical content exchange in a composite synthetic cell
  Abstract Engineering sophisticated behaviours in synthetic cells lacking complex biomolecular machinery remains a central challenge in synthetic biology. Here, we introduce a protein-free approach for dynamic content modulation in liposome-based synthetic cell…
  preprints Aileen Cooney, Wancheng Zhang, Lorenzo Di Michele, Yuval Elani 等 2025 置信度 0.74
• Error Correction Techniques in Synthetic Oligonucleotides and Synthetic DNA
  crossref A. N. Sinyakov, E. V. Kostina 2025-08-06T14:15:57Z 置信度 0.70
• How many plasmids can bacteria carry? A synthetic biology perspective
  Plasmids are pinnacle tools in synthetic biology and other biotechnological applications. They serve as the simplest approach to introduce recombinant DNA, which is then transcribed into RNA that functions as is or is translated into a protein of interest. Des…
  crossref Cholpisit Ice Kiattisewee 2025-12-04T14:20:00Z 置信度 0.70
• Genetic circuits in synthetic biology: broadening the toolbox of regulatory devices
  Devices sensing inputs and generating outputs are fundamental regulatory units, and as such are the basis of more complex regulatory networks. We provide an overview of regulatory devices used as fundamental regulatory building blocks in synthetic biology, and…
  crossref Marik M. Müller, Katja M. Arndt, Stefan A. Hoffmann 2025-03-07T01:47:22Z 置信度 0.70
• Synthetic biology meets neuromorphic computing: towards a bio-inspired olfactory perception system
  Abstract In this study, we explore how the combination of synthetic biology, neuroscience modeling, and neuromorphic electronic systems offers a new approach to creating an artificial system that mimics the natural sense of smell. We argue that a co-design app…
  crossref Kevin Max, Larissa Sames, Shimeng Ye, Jan Steinkühler 等 2025-07-10T09:23:22Z 置信度 0.70
• Environmental Census: Modeling Synthetic Biology Ecological Risk with Metagenomic Enzymatic Data and High-Performance Computing
  Engineered microorganisms in biotechnology present biosafety and environmental management challenges. As the synthetic biology market develops and deploys new technologies, these engineered organisms may escape into unintended environments. Improved predictive…
  europepmc John Docter, Cresten Mansfeldt 2025 置信度 0.80
• Issue Publication Information
  crossref 2025-10-17T07:27:37Z 置信度 0.70
• Mathematical Modeling of Synthetic Genetic Circuits
  Synthetic genetic circuits are the core research objects in synthetic biology, and the programming of cell behavior is achieved through the combination of engineered gene elements. Mathematical modeling provides crucial support for understanding and designing …
  crossref Haimei Wang 2025-12-05T03:00:02Z 置信度 0.70
• Issue Editorial Masthead
  crossref 2025-09-19T07:24:42Z 置信度 0.70
• Innovations in Yeast Synthetic Biology: Engineered Discovery Systems for Immunotherapy
  crossref Ethan W. Slaton, Natalie Clay, Nathan Phan, Blaise R. Kimmel 2025-08-13T20:44:47Z 置信度 0.70
• Issue Editorial Masthead
  crossref 2025-01-17T08:19:07Z 置信度 0.70
• Banking in the Digital Age: Transforming Financial Services
  crossref 2025-12-14T14:55:19Z 置信度 0.70
• Issue Publication Information
  crossref 2025-06-20T07:27:03Z 置信度 0.70
• Issue Publication Information
  crossref 2025-11-21T08:35:21Z 置信度 0.70
• Issue Editorial Masthead
  crossref 2025-07-18T07:14:32Z 置信度 0.70
• Issue Editorial Masthead
  crossref 2025-10-17T07:27:37Z 置信度 0.70
• Issue Editorial Masthead
  crossref 2025-03-21T03:50:57Z 置信度 0.70
• Issue Publication Information
  crossref 2025-05-16T03:28:21Z 置信度 0.70
• Issue Publication Information
  crossref 2025-12-19T08:34:52Z 置信度 0.70
• Issue Editorial Masthead
  crossref 2025-04-18T03:21:21Z 置信度 0.70
• Issue Editorial Masthead
  crossref 2025-12-19T08:34:52Z 置信度 0.70
• Issue Editorial Masthead
  crossref 2025-11-21T08:35:21Z 置信度 0.70
• Issue Editorial Masthead
  crossref 2025-06-20T07:27:03Z 置信度 0.70
• Issue Editorial Masthead
  crossref 2025-05-16T03:28:21Z 置信度 0.70
• Issue Publication Information
  crossref 2025-03-21T03:50:57Z 置信度 0.70
• Issue Publication Information
  crossref 2025-04-18T03:21:21Z 置信度 0.70
• Issue Publication Information
  crossref 2025-02-21T03:22:33Z 置信度 0.70
• Issue Publication Information
  crossref 2025-01-17T08:19:07Z 置信度 0.70
• Issue Editorial Masthead
  crossref 2025-02-21T03:22:33Z 置信度 0.70
• Issue Publication Information
  crossref 2025-09-19T07:24:42Z 置信度 0.70
• Issue Publication Information
  crossref 2025-07-18T07:14:32Z 置信度 0.70
• Synthetic Aptamer Mechanoreceptors Enable Cell-Specific Force Sensing and Temporal Control via DNA Circuits
  Abstract Cells interpret mechanical cues from their microenvironment with spatiotemporal precision to guide adaptive behaviors. However, engineering synthetic mechanosensing systems with both cell-specificity and programmability remains challenging, especially…
  crossref Tao Xu, Soumya Sethi, Christoph Drees, Andreas Walther 2025-07-18T04:40:11Z 置信度 0.70
• Synthetic Biology
  crossref David P. Clark, Nanette J. Pazdernik, Michelle R. McGehee, Bethany A. Rader 2025-07-23T08:55:31Z 置信度 0.70
• Single Cell Analysis for Alzheimers Integrating Transcriptomics and Synthetic Biology
  Alzheimer’s disease (AD) is a complex neurodegenerative disorder characterised by progressive cognitive decline. Single-cell transcriptomics has unveiled the complex cellular landscape of Alzheimer’s disease (AD), revealing distinct disease-associated cell sta…
  crossref Ramya Raghavan 2025-01-20T21:03:37Z 置信度 0.70
• Author response for "How many plasmids can bacteria carry? A synthetic biology perspective"
  crossref Cholpisit Kiattisewee 2025-07-31T21:09:21Z 置信度 0.70
• The international Genetically Engineered Machine (iGEM) Competition
  crossref 2025-02-13T02:48:16Z 置信度 0.70
• Orthogonal Inducible Transcriptional Control Systems for Investigation of Gene-Gene Interactions
  Abstract Genes do not act in isolation but through complex networks of interactions. While many double and triple gene interactions have been uncovered in Saccharomyces cerevisiae , most have been identified through overexpression or loss-of-function studies, …
  crossref Aslı Azizoğlu 2025-10-29T03:05:17Z 置信度 0.70
• 7. Synthetic Biology
  Ethical considerations in synthetic biology (SynBio) extend beyond biosafety and biosecurity concerns to encompass issues of justice and political dimensions, necessitating an approach that accounts for both theoretical frameworks and the practical realities o…
  crossref COMPOST Collective 2025-05-12T04:52:47Z 置信度 0.70
• Author response for "SYNTHETIC BIOLOGY ROUTES TO NEW AND EXTINCT NATURAL PRODUCTS"
  crossref Thomas J. Simpson 2025-03-21T17:01:20Z 置信度 0.70
• AI-directed gene fusing prolongs the evolutionary half-life of synthetic gene circuits
  Abstract Evolutionary instability is a persistent challenge in synthetic biology, often leading to the loss of heterologous gene expression over time. Here, we present STABLES, a novel gene fusion strategy that links a gene of interest (GOI) to an essential en…
  crossref Itamar Menuhin-Gruman, Matan Arbel, Doron Naki, Shaked Bergman 等 2025-02-12T21:05:20Z 置信度 0.70
• Synthetic Biology
  crossref Aparna B. Murukan, Ayisha A. Jabbar, Akshay Ramesh, Anu Melge 等 2024-05-10T22:26:59Z 置信度 0.70
• A promising novel strain of L. reuteri DSM20016 as a chassis for synthetic biology applications
  Limosilactobacillus reuteri strain DSM 20016 is specialised to colonize the human gut for much longer than other L. reuteri strains and most other Lactobacillaceae family members. These adaptations, along with its safe-to-consume food status and public accepta…
  crossref Alexander D. Duggan, Marcus M. Dillon, David R. McMillen 2025-03-26T08:08:16Z 置信度 0.70
• Synthetic biology - a review
  Synthetic biology, as a multidisciplinary field that includes biology, computer science, and engineering, has the aim to crate/modify current biology systems or other organisms such as enzymes, genetic circuits, and cells. In comparison to the conventional gen…
  crossref Aiša Galijatović 2026-03-30T11:11:27Z 置信度 0.70
• Optimization of regulatory DNA with active learning
  Abstract Many biotechnology applications rely on microbial strains engineered to express heterologous proteins at maximal yield. A common strategy for improving protein output is to design expression systems with optimized regulatory DNA elements. Recent advan…
  crossref Yuxin Shen, Grzegorz Kudla, Diego A. Oyarzún 2025-06-27T23:50:10Z 置信度 0.70
• Genomic Perception Fusion: A Lightweight, Interpretable Kernel for Protein Functional Tuning
  Abstract Protein design has been transformed by deep generative models—but at the cost of interpretability, accessibility, and integration with sparse experimental feedback. Here, we introduce Genomic Perception Fusion (GPF) , a biologically inspired algorithm…
  crossref Syed Ubaid Qurashi 2025-11-08T01:10:47Z 置信度 0.70
• Preventing Multimer Formation in Commonly Used Synthetic Biology Plasmids
  crossref Elizabeth Vaisbourd, Anat Bren, Uri Alon, David S. Glass 2025-03-18T20:22:21Z 置信度 0.70
• Synthetic and Engineering Biology in Australia: Advances in Infrastructure, Coordination and Impact
  ABSTRACT Synthetic and engineering biology in Australia is a vibrant and expanding area, with the potential to contribute to Australian priorities, industry growth and international initiatives. This paper provides a progress update on the field in Australia s…
  europepmc Robert E. Speight 2025 置信度 0.80
• Broad-Host-Range Synthetic Biology: Rethinking Microbial Chassis as a Design Variable
  crossref Dennis Tin Chat Chan, Johan Bjerg, Hans C. Bernstein 2025-09-18T09:40:12Z 置信度 0.70
• Noise-guided tuning of synthetic protein waves in living cells
  Abstract Biological systems use protein circuits to organize cellular activities in space and time, but engineering synthetic dynamics is challenging due to stochastic effects of genetic and biochemical variation on circuit behavior. Genetically encoded oscill…
  crossref Dennis T. Bolshakov, Elliott W. Z. Weix, Thomas M. Galateo, Rohith Rajasekaran 等 2025-03-23T23:43:18Z 置信度 0.70
• Gearing up Golden Braid assembly for plant synthetic genomics with RepTiles
  Abstract We have developed RepTiles, a system for generating traces of random DNA for synthetic genomics applications. RepTiles reduced the burden associated with the manual design of long DNA from standard biological parts. We are applying RepTiles to the con…
  crossref Viktoria Petrova, Dejan Andrejic, Tobias Finkenrath, Josepha Grewer 等 2025-03-02T07:55:22Z 置信度 0.70
• BPS2025 - Expanding RNA functions with synthetic biology
  crossref Hirohide Saito 2025-02-13T12:15:01Z 置信度 0.70
• Metabolite-Responsive Control of Transcription by Phase Separation-Based Synthetic Organelles
  crossref Carolina Jerez-Longres, Wilfried Weber 2025-02-15T12:48:51Z 置信度 0.70
• Multiphase Induction Motor Drives: Control, Fault Diagnosis, and Multilevel Inverter Integration
  crossref 2025-12-14T14:55:19Z 置信度 0.70
• AI and Synthetic Biology
  crossref 2025-11-11T01:53:53Z 置信度 0.70
• Synthetic Phase Variation for Engineered Microbial Consortia
  Abstract Some biochemical functions can be performed more efficiently when split into different tasks, each performed by distinct strains within a microbial consortium. Due to the distinct growth dynamics of each strain, uncontrolled consortia have unstable co…
  crossref Matthieu F. Kratz, Richard M. Murray, Michael B. Elowitz 2025-08-26T04:35:12Z 置信度 0.70
• Competitions for tyrosine breakdown: In synthetic microbial communities and between a gut microbial pathway and a human pathway
  ABSTRACT Tyrosine, a versatile amino acid that undergoes diverse transformations to produce both beneficial and detrimental metabolites. The modulation of these metabolites results from direct competition among different metabolic pathways responsible for the …
  crossref Madison Mitchem, Clint W. Pauling, Dhara D. Shah 2025-07-08T02:30:12Z 置信度 0.70
• Synthetic biology routes to new and extinct natural products
  Developments in genome sequencing and genetic engineering in bacteria and fungi and allowed production of new natural products and engineered strains with optimised production of new and/or preferred metabolites.
  crossref Thomas J. Simpson 2025-03-21T06:22:00Z 置信度 0.70
• A synthetic cell with integrated DNA self-replication and membrane biosynthesis
  Abstract The emergence, organization, and persistence of cellular life are the result of the functional integration of metabolic and genetic networks. Here, we engineer phospholipid vesicles that can operate three essential functions, namely transcription-tran…
  crossref Ana María Restrepo Sierra, Federico Ramirez Gomez, Mats van Tongeren, Laura Sierra Heras 等 2025-01-14T13:15:18Z 置信度 0.70
• Data-informed model reduction for inference and prediction from non-identifiable models
  Abstract Many mathematical models in the field of theoretical biology involve challenges relating to parameter identifiability. Non-identifiability implies that different combinations of parameter values lead to indistinguishable solutions of the mathematical …
  crossref Matthew J. Simpson 2025-03-22T00:04:01Z 置信度 0.70
• Scientometric analysis of mycosporine-like amino acids from 1989 to 2025: Current trends and applications.
  Living organisms on the Earth surface are facing serious threats from both upcoming solar ultraviolet radiation (UVR) and widespread use of synthetic sunscreen. Concerns about the environmental and health impacts of synthetic sunscreen agents have spurred inte…
  pubmed Lal R, Kannaujiya VK 2026 置信度 0.82