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• Fusions of catalytically inactive RusA to FokI nuclease coupled with PNA enable programable site-specific double-stranded DNA breaks
  preprints 2024 置信度 0.74
• Leaky ribosomal scanning enables tunable translation of bicistronic ORFs in green algae
  preprints 2024 置信度 0.74
• Deletion of HindIIR and HindIIIR improves DNA transfer via electroporation to <i>Haemophilus influenzae</i> Rd
  preprints 2024 置信度 0.74
• Expanding the toolkit for ploidy manipulation in Chlamydomonas reinhardtii
  preprints 2024 置信度 0.74
• A tool to pulse-label yeast Nuclear Pore Complexes in imaging and biochemical experiments
  preprints 2025 置信度 0.74
• Muscular Dystrophies and Therapeutic Potential of Medicinal Plants
  preprints 2024 置信度 0.74
• A differentiable Gillespie algorithm for simulating chemical kinetics, parameter estimation, and designing synthetic biological circuits
  preprints 2024 置信度 0.74
• Successful establishment of an exogenous gene expression system in <i>Chlamydomnas</i> chloroplast based on viral replication elements
  preprints 2024 置信度 0.74
• Systematic screen of RNA binding proteins that enhance circular RNA translation
  preprints 2024 置信度 0.74
• Cell cycle-dependent protein dynamics in budding yeast resolved by deconvolution of bulk proteomics
  preprints 2026 置信度 0.74
• Sticky enzymes: increased metabolic efficiency via substrate-dependent enzyme clustering
  preprints 2024 置信度 0.74
• The spatial proteome of the <i>Plasmodium falciparum</i> schizont illuminates the composition and evolutionary trajectories of its organelles
  preprints 2025 置信度 0.74
• Synthetic Biology Continues to Grow
  crossref Huimin Zhao 2024-01-19T08:24:56Z 置信度 0.70
• Environment and synthetic biology
  crossref Hongzhi Tang, Maoyong Song 2024-03-23T09:34:51Z 置信度 0.70
• International Conference on Environmental, Chemical, and Synthetic Biology towards Sustainable Development Goals (ICECSSD-2024)
  crossref 2025-05-23T16:13:21Z 置信度 0.70
• Embedded Extremum Seeking: A Bio-synthetic Optimiser
  Abstract In cybergentics, internal control uses synthetic genetic circuits to bypass the sensing and actuation limits of external control. Currently, embedded controllers are limited to basic controllers, like PID. Here, we introduce the Embedded Extremum Seek…
  preprints Benjamin Smart, Lucia Marucci, Ludovic Renson 2024 置信度 0.74
• Synthetic RNA biology
  crossref Beatrix Suess 2024-04-14T23:58:01Z 置信度 0.70
• Mechanistic Model-Driven Biodesign in Mammalian Synthetic Biology
  crossref Yin Hoon Chew, Lucia Marucci 2024-03-05T16:08:56Z 置信度 0.70
• Issue Publication Information
  crossref 2024-12-20T03:29:39Z 置信度 0.70
• Issue Editorial Masthead
  crossref 2024-12-20T03:29:39Z 置信度 0.70
• Application of Synthetic Biology to the Biosynthesis of Polyketides
  crossref Xia Chen, Xinying Li, Genlin Zhang, Chao Wang 等 2024-08-19T06:19:18Z 置信度 0.70
• Applications of Synthetic Biology Within Coral Conservation
  crossref Kayla Chin 2024-04-15T20:39:31Z 置信度 0.70
• Extracellular Ligand-Responsive Translational Regulation of Synthetic mRNAs using Engineered Receptors
  Abstract mRNA drugs can encode any protein and are regarded as a promising therapeutic modality. In this study, we developed a new mRNA system allowing extracellular ligand-responsive translational regulation. This system consists of three mRNAs, two of which …
  crossref Hideyuki Nakanishi, Keiji Itaka 2024-09-29T00:50:13Z 置信度 0.70
• Synthetic gene circuits that selectively target RAS-driven cancers
  Abstract Therapies targeting mutated RAS, the most frequently mutated oncogene in human cancers, could benefit millions of patients. Recently approved RAS inhibitors represent a breakthrough, but are limited to a specific KRAS G12C mutation and prone to resist…
  preprints Gabriel Senn, Leon Nissen, Yaakov Benenson 2024 置信度 0.74
• Synthetic Biology
  crossref 2024-03-11T22:02:42Z 置信度 0.70
• The Role of Artificial Intelligence (AI) in Synthetic Biology and Biosecurity Implications
  crossref Leyma Pérez, De Haro 2024-08-08T18:41:23Z 置信度 0.70
• Metabolite-responsive Control of Transcription by Phase Separation-based Synthetic Organelles
  Abstract Living natural materials have remarkable sensing abilities that translate external cues into functional changes of the material. The reconstruction of such sensing materials in bottom-up synthetic biology provides the opportunity to develop synthetic …
  preprints Carolina Jerez-Longres, Wilfried Weber 2024 置信度 0.74
• Programming Juxtacrine-Based Synthetic Signaling Networks in a Cellular Potts Framework
  crossref Calvin Lam, Leonardo Morsut 2024-03-11T22:02:42Z 置信度 0.70
• Special Issue on Artificial Intelligence for Synthetic Biology
  crossref Hector García Martín, Stanislav Mazurenko, Huimin Zhao 2024-01-12T16:49:07Z 置信度 0.70
• Synthetic biology in relation to nature conservation: briefing document
  crossref 2024-03-13T20:40:46Z 置信度 0.70
• Synthetic Biology in Nigeria: The Level of Awareness amongst Stakeholders
  crossref Jude Chukwuemeke Igborgbor, Onyeka Kingsley Nwosu, Abubakar Madika, Geoffrey Otim 等 2024-09-30T05:19:17Z 置信度 0.70
• Biology System Description Language (BiSDL): a modeling language for the design of multicellular synthetic biological systems
  Abstract Background The Biology System Description Language (BiSDL) is an accessible, easy-to-use computational language for multicellular synthetic biology. It allows synthetic biologists to represent spatiality and multi-level cellular dynamics inherent to m…
  crossref Leonardo Giannantoni, Roberta Bardini, Alessandro Savino, Stefano Di Carlo 2024-01-14T22:20:10Z 置信度 0.70
• IWBDA 2022: Toward a Modular Future of Synthetic Biology Driven by Bio-Design Automation
  crossref Ayush Pandey 2024-06-21T03:20:22Z 置信度 0.70
• A Mammalian-Based Synthetic Biology Toolbox to Engineer Membrane–Membrane Interfaces
  crossref Hossein Moghimianavval, Sonisilpa Mohapatra, Allen P. Liu 2024-03-05T16:08:56Z 置信度 0.70
• Synthetic biology
  crossref Joachim Boldt 2024-10-04T21:43:18Z 置信度 0.70
• VirtualIce: Half-synthetic CryoEM Micrograph Generator
  Abstract Single particle cryo-electron microscopy (cryoEM) is going through a phase of rapid optimization focused on increasing the efficiency, accuracy, and automation of every step in the data pipeline. Machine learning models in particular have been making …
  crossref Alex J. Noble 2024-09-29T23:20:18Z 置信度 0.70
• Preparing for the future of precision medicine: synthetic cell drug regulation
  Abstract Synthetic cells are a novel class of cell-like bioreactors, offering the potential for unique advancements in synthetic biology and biomedicine. To realize the potential of those technologies, synthetic cell-based drugs need to go through the drug app…
  crossref Kira Sampson, Carlise Sorenson, Katarzyna P Adamala 2024-01-23T15:42:41Z 置信度 0.70
• Plant Synthetic Promoters
  The article features the structure and functions of plant synthetic promoters frequently exercised to precisely regulate complex regulatory routes. The composition of plant native promoters together with interacting proteins is presented to provide a better un…
  crossref Piotr Szymczyk, Małgorzata Majewska 2024-04-18T10:55:13Z 置信度 0.70
• From resonance to chaos: modulating spatiotemporal patterns through a synthetic optogenetic oscillator
  Abstract Oscillations are a recurrent phenomenon in biological systems across scales, including circadian clocks, metabolic oscillations and embryonic genetic oscillators. Despite their fundamental significance in biology, deciphering core principles of biolog…
  crossref Jung Hun Park, Gábor Holló, Yolanda Schaerli 2024-03-30T00:55:10Z 置信度 0.70
• Biosecurity in the Age of Synthetic Biology
  crossref Leyma Pérez De Haro 2024-08-08T18:41:23Z 置信度 0.70
• Gradient Oriented Active Learning for Candidate Drug Design
  Abstract One of the primary challenges of drug design is that the complexity of Biology often comes to the fore only when proposed candidates are eventually tested in reality. This necessitates making the discovery process more efficient by making it active ly…
  crossref Venkatesh Medabalimi 2024-07-16T00:55:10Z 置信度 0.70
• A synthetic method to assay polycystin channel biophysics
  ABSTRACT Ion channels are biological transistors that control ionic flux across cell membranes to regulate electrical transmission and signal transduction. They are found in all biological membranes and their conductive state kinetics are frequently disrupted …
  crossref Megan Larmore, Orhi Esarte Palomero, Neha P. Kamat, Paul G. DeCaen 2024-05-08T08:57:38Z 置信度 0.70
• A comprehensive review of Microfluidic approaches in cell-free synthetic biology
  Cell-free synthetic biology has gained increasing popularity owing to its ability to elucidate biological functions in isolation from intricate cellular environments and the capacity to build increasingly complex biochemical systems in vitro . But cell-free tr…
  crossref Amogh Kumar Baranwal, Sebastian J. Maerkl 2024-05-06T00:43:09Z 置信度 0.70
• Computational Synthetic Biology Enabled through JAX: A Showcase
  crossref Olivia Gallup, Kirill Sechkar, Sebastian Towers, Harrison Steel 2024-09-04T14:13:32Z 置信度 0.70
• dCas12a:Pre-crRNA: A New Tool to Induce mRNA Degradation in Saccharomyces cerevisiae Synthetic Gene Circuits
  We describe a new way to trigger mRNA degradation in Saccharomyces cerevisiae synthetic gene circuits. Our method demands to modify either the 5'- or the 3'-UTR that flanks a target gene with elements from the pre-crRNA of type V Cas12a proteins and expresses …
  crossref Lifang Yu, Mario Andrea Marchisio 2024-03-11T22:02:42Z 置信度 0.70
• Synthetic cell-based tissues for bottom-up assembly of artificial lymphatic organs
  Abstract Synthetic cells have emerged as novel biomimetic materials for studying fundamental cellular functions and enabling new therapeutic approaches. However, replicating the structure and function of complete tissues as self-organized 3D collectives has re…
  crossref Anna Burgstaller, Erick Angel Lopez Lopez, Oskar Staufer 2024-10-02T13:30:29Z 置信度 0.70
• Light-based juxtacrine signaling between synthetic cells
  Abstract Cell signaling through direct physical cell-cell contacts plays vital roles in biology during development, angiogenesis, and immune response. Intercellular communication mechanisms between synthetic cells constructed from the bottom up are majorly rel…
  crossref Hossein Moghimianavval, Kyle J. Loi, Sung-Won Hwang, Yashar Bashirzadeh 等 2024-01-08T16:06:45Z 置信度 0.70
• Emergence and Supervenience
  This chapter explores some influential ways in which the relation between the mind and the body is understood in contemporary philosophy, in particular the notions of emergence and supervenience. It includes a close investigation of the work of Roger Sperry an…
  crossref Henri Atlan, Inja Stracenski 2025-09-24T10:19:02Z 置信度 0.70
• Dual-function logic gates based on CRISPRi
  Abstract Developing logic gate circuits that are programmable and reliable for specific functions is a central goal in synthetic biology. Traditional synthetic circuits often rely on protein regulators, which face scalability and resource burden limitations. T…
  preprints Zhiwu Yao, Shaobin Guo 2024 置信度 0.74
• Review: Challenges in observing transcription–translation for bottom-up synthetic biology — R0/PR3
  crossref 2025-01-28T03:01:02Z 置信度 0.70
• Review: Challenges in observing transcription–translation for bottom-up synthetic biology — R0/PR2
  crossref 2025-01-28T03:01:02Z 置信度 0.70
• Design of a self-regulating mRNA gene circuit
  ABSTRACT Protein expression from mRNA in vivo is predominately controlled via regulatory feedback mechanisms that adjust the level of mRNA transcription. However, for positive sense single-stranded RNA viruses, protein expression is often controlled via second…
  crossref Eric C. Dykeman 2024-04-24T01:50:25Z 置信度 0.70
• Synthetic Biology for Therapeutics
  crossref 2024-11-05T06:23:36Z 置信度 0.70
• Engineering an anti-CD206-synNotch receptor: insights into the development of novel synthetic receptors
  Abstract Immune cells play a pivotal role in the establishment, growth and progression of tumors at primary and metastatic sites. Macrophages, in particular, play a critical role in suppressing immune responses and promoting an anti-inflammatory environment th…
  crossref Sofija Semeniuk, Bin-Zhi Qian, Elise Cachat 2024-02-08T00:15:20Z 置信度 0.70
• Fine-Tuning Gene Expression in Bacteria by Synthetic Promoters
  crossref Sezer Okay 2024-07-27T20:39:54Z 置信度 0.70
• Promoters and Synthetic Promoters in Trichoderma reesei
  crossref Muhammad Adnan, Gang Liu 2024-07-27T20:39:54Z 置信度 0.70
• A spring-loaded and leakage-tolerant synthetic gene switch for in-vitro detection of DNA and RNA
  ABSTRACT Nucleic acid tests (NATs) are essential for biomedical diagnostics. Traditional NATs, often complex and expensive, have prompted the exploration of Toehold-Mediated Strand Displacement (TMSD) circuits as an economical alternative. However, the wide ap…
  crossref Krishna Gupta, Elisha Krieg 2024-02-14T20:50:13Z 置信度 0.70
• Chemical Reaction Models in Synthetic Promoter Design in Bacteria
  crossref Ozan Kahramanoğulları 2024-07-27T20:39:54Z 置信度 0.70
• Towards programming-based synthetic genetic circuit enabled high-lysine maize
  crossref Md. Mahmudul Hasan 2024-05-21T16:20:37Z 置信度 0.70
• Chapter 1 Programming cells with synthetic biology
  crossref Recep Erdem Ahan, Derin Akman, Ece Avcı, Urartu Özgür Şafak Şeker 2024-11-05T06:23:36Z 置信度 0.70
• In Silico Design, In Vitro Construction, and In Vivo Application of Synthetic Small Regulatory RNAs in Bacteria
  crossref Michel Brück, Bork A. Berghoff, Daniel Schindler 2024-03-11T22:02:42Z 置信度 0.70
• Issue Publication Information
  crossref 2024-05-17T07:55:43Z 置信度 0.70
• Modulating Microbial Materials - Engineering Bacterial Cellulose with Synthetic Biology
  crossref Koray Malcı, Ivy S. Li, Natasha Kisseroudis, Tom Ellis 2024-11-07T21:01:42Z 置信度 0.70
• Issue Editorial Masthead
  crossref 2024-05-17T07:55:43Z 置信度 0.70
• Issue Editorial Masthead
  crossref 2024-02-16T08:53:53Z 置信度 0.70
• Issue Publication Information
  crossref 2024-03-15T07:25:11Z 置信度 0.70
• Reviewer #2 (Public review): De novo-designed minibinders expand the synthetic biology sensing repertoire
  crossref 2024-10-30T11:10:51Z 置信度 0.70
• Reviewer #1 (Public Review): De novo-designed minibinders expand the synthetic biology sensing repertoire
  crossref 2024-04-19T08:25:58Z 置信度 0.70
• Synthetic biology, once hailed as a moneymaker, meets tough times
  crossref 2024-08-22T18:06:17Z 置信度 0.70
• Issue Publication Information
  crossref 2024-02-16T08:53:53Z 置信度 0.70
• Issue Editorial Masthead
  crossref 2024-01-19T08:24:56Z 置信度 0.70
• Issue Publication Information
  crossref 2024-11-15T09:19:12Z 置信度 0.70
• Issue Publication Information
  crossref 2024-09-20T07:18:27Z 置信度 0.70
• Issue Editorial Masthead
  crossref 2024-10-18T07:28:58Z 置信度 0.70
• Issue Publication Information
  crossref 2024-06-21T07:20:22Z 置信度 0.70
• Issue Editorial Masthead
  crossref 2024-11-15T09:19:12Z 置信度 0.70
• Issue Publication Information
  crossref 2024-01-19T08:24:56Z 置信度 0.70
• Mammalian Synthetic Systems
  crossref 2024-03-05T16:08:56Z 置信度 0.70
• Advances in synthetic biology
  crossref Dr. Shue Wang 2024-09-26T16:37:55Z 置信度 0.70
• Issue Publication Information
  crossref 2024-10-18T07:28:58Z 置信度 0.70
• Programming CRISPRi-dCas9 to control the lifecycle of bacteriophage T7
  Abstract CRISPR interference (CRISPRi) based on catalytically dead Cas9 nuclease of Streptococcus pyogenes is a programmable and highly flexible tool to interrogate gene function and essentiality in bacteria due to its ability to block transcription elongation…
  crossref Tobias Bergmiller 2024-05-16T00:10:16Z 置信度 0.70
• Reviewer #2 (Public Review): De novo-designed minibinders expand the synthetic biology sensing repertoire
  crossref 2024-04-19T08:25:58Z 置信度 0.70
• Synthetic Biology for a Sustainable Planet: Innovations in Carbon Capture
  Abstract: “Synthetic Biology for a Sustainable Planet: Innovations in Carbon Capture” offers a comprehensive, research-level analysis of how engineered biological and biohybrid systems can be mobilized to mitigate climate change. The book situates synthetic bi…
  crossref Murali Krishna Pasupuleti 2025-11-21T01:21:02Z 置信度 0.70
• Issue Editorial Masthead
  crossref 2024-07-19T07:46:17Z 置信度 0.70
• Issue Publication Information
  crossref 2024-07-19T07:46:17Z 置信度 0.70
• Issue Editorial Masthead
  crossref 2024-04-19T07:35:46Z 置信度 0.70
• Issue Publication Information
  crossref 2024-08-16T07:18:14Z 置信度 0.70
• Light-triggered protease-mediated release of actin-bound cargo from synthetic cells
  Abstract Synthetic cells offer a versatile platform for addressing biomedical and environmental challenges, due to their modular design and capability to mimic cellular processes such as biosensing, intercellular communication, and metabolism. Constructing syn…
  crossref Mousumi Akter, Hossein Moghimianavval, Gary D. Luker, Allen P. Liu 2024-09-16T01:39:56Z 置信度 0.70
• Iterative SCRaMbLE for Engineering Synthetic Genome Modules and Chromosomes
  Abstract Synthetic biology offers the possibility of synthetic genomes with customised gene content and modular organisation. In eukaryotes, building whole custom genomes is still many years away, but work in Saccharomyces cerevisiae yeast is closing-in on the…
  preprints Xinyu Lu, Klaudia Ciurkot, Glen-Oliver F. Gowers, William M Shaw 等 2024 置信度 0.74
• Issue Editorial Masthead
  crossref 2024-09-20T07:18:27Z 置信度 0.70
• Synthetic dosage-compensating miRNA circuits for quantitative gene therapy
  A longstanding challenge in gene therapy is expressing a dosage-sensitive gene within a tight therapeutic window. For example, loss of MECP2 function causes Rett syndrome, while its duplication causes MECP2 duplication syndrome. Viral gene delivery methods gen…
  crossref Michael James Flynn, Acacia M. Mayfield, Rongrong Du, Viviana Gradinaru 等 2024-03-14T23:00:35Z 置信度 0.70
• Issue Editorial Masthead
  crossref 2024-03-15T07:25:11Z 置信度 0.70
• Synthetic genome modules designed for programmable silencing of functions and chromosomes
  Unlike in bacteria, eukaryotes rarely cluster sets of genes in their genomes according to function, instead having most genes spread randomly across different chromosomes and loci. However, with the advent of genome engineering, synthetic co-location of genes …
  crossref Xinyu Lu, William M Shaw, Anima Sutradhar, Giovanni Stracquadanio 等 2024-03-22T23:50:18Z 置信度 0.70
• Artificial Intelligence and Synthetic Biology Are Not Harbingers of Doom
  Contrary to many people’s fears, artificial intelligence (AI) can be a positive force in advancing biological research and biotechnology. The assumption that AI will super-empower the risks that already exist for the misuse of biotech to develop and spread pat…
  crossref David A. Bray 2024-04-03T12:17:34Z 置信度 0.70
• Issue Editorial Masthead
  crossref 2024-08-16T07:18:14Z 置信度 0.70
• Issue Publication Information
  crossref 2024-04-19T07:35:46Z 置信度 0.70
• Issue Editorial Masthead
  crossref 2024-06-21T07:20:22Z 置信度 0.70
• :<i>Programmable Planet: The Synthetic Biology Revolution</i>
  crossref Sara Green 2024-11-15T18:22:58Z 置信度 0.70
• Systems Biology and Synthetic Biology with Populations of Bacteria
  crossref 2024-12-12T00:10:02Z 置信度 0.70
• Engineered yeast multicellularity via synthetic cell-cell adhesion and direct-contact signalling
  Abstract Coordination of behaviour in multicellular systems is one the main ways that nature increases the complexity of biological function in organisms and communities. While Saccharomyces cerevisiae yeast is used extensively in research and biotechnology, i…
  crossref Fankang Meng, William M. Shaw, Yui Kei Keith Kam, Tom Ellis 2024-06-25T01:20:23Z 置信度 0.70