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Floral (FNs) and extrafloral nectaries (EFNs) are key plant microhabitats that mediate interactions among plants, insects, and microorganisms, yet their associated fungal communities remain poorly characterized, especially in tropical ecosystems. Here, we inve…
pubmed
Reis JBAD, Schirmer SC, Vale HMMD
2026 Aug
置信度 0.82
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In the dairy sector of Bangladesh, subclinical mastitis (SCM) is a substantial and frequently undiagnosed challenge, with reported prevalence rates of 60%-77% in cattle and approximately 52% in buffaloes. Due to its complex characteristics and progressive deve…
pubmed
Masum MHU, Nayem MR, Mahdeen AA, Sultana S 等
2026 Sep
置信度 0.82
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Head and neck squamous cell carcinoma (HNSCC) presents a significant global health challenge, characterized by late-stage diagnosis and high rates of locoregional recurrence. Traditional tissue biopsy, while considered the gold standard, is invasive and often …
pubmed
Briaunys Milan T, Garcia Pereira C, Pereira de Souza R, Soares Schalch M 等
2026 Aug 5
置信度 0.82
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To investigate the predictive value of peripheral blood cfDNA breast cancer gene mutation profiling for postoperative pathological malignancy in BI-RADS 4 breast nodules.
pubmed
Lyu G, Duan H, Sheng X, Liu L 等
2026
置信度 0.82
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Glioblastoma (GB) exhibits marked tumor microenvironmental heterogeneity, contributing to both therapy resistance and poor survival outcomes. Intercellular adhesion molecule 1 (ICAM1) is an inflammation-associated adhesion molecule implicated in immune-stromal…
pubmed
Gandhi S, Ocaña-Tienda B, Bettencourt MM, Singh OS 等
2026 Jan-Dec
置信度 0.82
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Camellia hamyenensis Ninh & Le is a yellow tea species endemic to Vietnam. In this study, the complete chloroplast genome of this species was sequenced, assembled, and annotated. The 156,613-bp plastome has a GC content of 37.32% and comprises an 86,187-bp…
pubmed
Nguyen MP, Ho VT
2026
置信度 0.82
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Atypical Brucella spp., which include Brucella inopinata and related lineages, have emerged as unconventional pathogens with an expanding host range, particularly among exotic amphibians. A captive waxy monkey treefrog ( Phyllomedusa bicolor ) presented with a…
pubmed
Kim M, Hmohn ZZW, Han JI
2026
置信度 0.82
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Muscular dystrophies (MDs) are a genetically heterogeneous group of disorders, posing significant diagnostic challenges, especially in populations with high consanguinity. Despite advances in genetic testing, a substantial proportion of patients remain undiagn…
pubmed
Soltani N, Shahbazi Z, Fallah MS, Karimipoor M 等
2026
置信度 0.82
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Transplant-associated thrombotic microangiopathy (TA-TMA) is a life-threatening complication of hematopoietic stem cell transplantation (HSCT). Previous reports in the United States have suggested that TA-TMA is caused by complement-related genetic variants. H…
pubmed
Yamada A, Nagasawa S, Nakagawa M, Kamimura S 等
2026
置信度 0.82
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To reveal the genetic status of Korean pine germplasm resources, explore SNP loci associated with important economic traits of Korean pine, and develop breeding markers, the economic traits of 100 clones from 7 populations (planted in 6 seed orchards) were obs…
pubmed
Yan P, Li G, Zhang L, Xie Z 等
2026
置信度 0.82
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Preterm birth (PTB), defined as delivery before 37 weeks, is a major cause of neonatal morbidity and mortality worldwide. Evidence suggests that both epigenetic dysregulation and gut microbial imbalance contribute to the inflammatory and metabolic disturbances…
pubmed
Huang P, Cai Z
2026
置信度 0.82
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Actinomycetes are a diverse group of microorganisms that play essential roles in environmental processes and drug discovery, particularly through the production of bioactive secondary metabolites. In Indonesia, most actinomycetes have been isolated predominant…
pubmed
Karissa E, Purwaningtyas WE, Akinniyi GA, Kim H 等
2026 Jul 29
置信度 0.82
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POLG (DNA polymerase γ catalytic subunit)-related mitochondrial diseases are among the most severe primary mitochondrial disorders and are characterized by progressive neurodegeneration with prominent dopaminergic involvement. However, the cell type-spec…
pubmed
Chen A, Yangzom T, Sullivan GJ, Liang KX
2026 Jul 31
置信度 0.82
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The global molecular epidemiology of Mycobacterium avium subsp. paratuberculosis (MAP) has been well documented in North America and Europe, but the population-genetic framework of the East Asian lineages is underrepresented, hindering a complete understanding…
pubmed
Lee JH, Kyung SM, Lee ES, Lee HG 等
2026 Jul
置信度 0.82
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Tumor protein p53 (TP53) alterations are frequently reported in canine cancers but remain incompletely characterized due to differences in reference genomes and sequencing cost.
pubmed
Mathiyalagan R, Lee C, Jo Y, Lee J 等
2026 Jul
置信度 0.82
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Equine Rotavirus A (ERVA) is a major cause of acute diarrhea in neonatal foals, leading to significant economic losses. Genetic variation and global transmission complicate disease control efforts.
pubmed
Pham TT, Lee DH, Ko EJ
2026 Jul
置信度 0.82
-
One nucleotide substitution in nucleotide 525 of HLA-B*15:11:01:01 results in a novel allele HLA-B*15:11:10.
pubmed
Yang KL, Lin PY
2026 Aug
置信度 0.82
-
The analysis of cell-free DNA (cfDNA) in blood is expected to serve as a new diagnostic method for early cancer detection and treatment monitoring by examining trace amounts of ctDNA derived from cancer cells. In cancer patients, ctDNA circulates in the bloods…
pubmed
Ishioka C
2026 Jul
置信度 0.82
-
Noninvasive cell-free DNA (cfDNA) metagenomic sequencing enables hypothesis-free detection of microbial pathogens in patients with suspected infections. However, its clinical sensitivity is often limited by the overwhelming background of host-derived cfDNA, wh…
pubmed
Liao T, Ding SC, Yu J, Gu W
2026 Aug 5
置信度 0.82
-
Genetic diversity is critical to long-term survival of species but can be eroded by population declines driven by human pressures. Temporal genetic monitoring of threatened species can reveal changes in genetic diversity over time, providing key data for conse…
pubmed
Fearing A, Smith KL, Feldheim KA, Moore ABM 等
2026 Aug 5
置信度 0.82
-
Anaerobic methane oxidation coupled to extracellular electron transfer (EET) has shown promising application in bioenergy recovery, yet whether this process can simultaneously drive biological nitrogen fixation (BNF) remains unexplored. Here, we demonstrated t…
pubmed
Yu L, Jia R, Li S, Guo X 等
2026 Aug 4
置信度 0.82
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Glyphosate (Gly), a widely used organophosphorus pesticide, has raised concern due to its environmental persistence and adverse health effects. Conventional detection methods are often limited by high expenses, complex operations, and insufficient sensitivity,…
pubmed
Wang Y, Liu Z, Yang J, Jin R 等
2026 Jul 30
置信度 0.82
-
HLA-B*13:220 differs from HLA-B*13:02:01:01 by a non-synonymous substitution in exon 2.
pubmed
Machado EFG, Linhares JA, Dugonski ME, Cazarote HB 等
2026 Jul
置信度 0.82
-
Discovery of a novel HLA class II allele, HLA-DRB3*02:02:56, identified using two NGS methods.
pubmed
Cundiff J, Ponisciak M, Liacini A, Berka N
2026 Jul
置信度 0.82
-
Soybean (Glycine max (L.) Merrill), a vital food and oilseed crop native to China, has the development of high-yield and high-quality new varieties as a core objective in soybean breeding. However, studies on genetic diversity and marker-trait associations for…
pubmed
Zong H, Li X, Liu S, Bao H 等
2026
置信度 0.82
-
Although transcriptome studies have been performed in cell culture models of HBV infection, the in vivo hepatic transcriptional response to persistent HBV expression remains incompletely characterized. In addition, whether HBV is associated with activation of …
pubmed
Wang Z, Zhao M, Fu Y, Liu L 等
2026 Aug 5
置信度 0.82
-
Maternal diabetes during pregnancy increases the risk of metabolic and cardiac disorders in offspring. Nevertheless, the mechanism by which intrauterine hyperglycemia affects neonatal cardiac remodeling remains uncertain. This study aims to characterize the pr…
pubmed
Xiao Z, Gao L, Wang Y, Yang C 等
2026 Jul 29
置信度 0.82
-
Cancer type classification is challenging due to tumor heterogeneity and undefined tissue of origin (TOO), particularly in cancers of unknown primary (CUP) and multiple primary cancers (MPC). Accurate TOO identification is critical for guiding treatment and pr…
pubmed
Zhang Y, Liu L, Bao H, Xu K 等
2026 Aug 5
置信度 0.82
-
The novel HLA-C*04:03:01:07 allele differs from HLA-C*04:03:01:01 at position gDNA 175 (G > C) in intron 1.
pubmed
Tambe M, Das D, Firfire A, Rajak J 等
2026 Aug
置信度 0.82
-
Accurate identification of Plasmodium species is essential for appropriate malaria management, particularly in cases of Plasmodium vivax (P. vivax), in which relapse prevention requires radical cure. A diagnostically challenging case of late-onset malaria in a…
pubmed
Stensvold CR, Nielsen HV, White JK, Szeps J 等
2026 Aug 4
置信度 0.82
-
Biliary tract cancers (BTC), including cholangiocarcinoma, gallbladder cancer, and ampullary cancer, remain poor-prognosis tumours. Chemo-immunotherapy is now established as the first-line standard of care. In parallel, precision medicine is now well establish…
pubmed
Lamarca A, Harding JJ, Oh DY
2026 Jun 8
置信度 0.82
-
Geminiviruses are among the most threatening emerging insect-borne viruses and are responsible for serious outbreaks worldwide. Climate change (i.e. higher temperatures) could further exacerbate their impact on crops, highlighting the need for new diagnostic a…
pubmed
Miozzi L, Rotunno S, Frascati F, Marra M 等
2026 Aug
置信度 0.82
-
Fibromyalgia (FM) has been increasingly studied in the context of gut-brain-immune interactions, and several reports have suggested an association between FM and alterations in gut or oral microbial communities. However, prior studies have often suffered from …
pubmed
Celik G, Yanik E, Inan N, Yalinay AM
2026 Jul
置信度 0.82
-
DNA methylation (DNAm) has long been a commonly investigated biomarker in biomedical research. The current gold standard for DNAm detection is bisulfite sequencing which requires dedicated alignment tools that can handle reduced sequence complexity. One common…
pubmed
Sutter C, Haas C, Neubauer J
2026 Aug 4
置信度 0.82
-
Antimicrobial resistance (AMR) in Neisseria gonorrhoeae is a global public health concern, particularly due to increasing resistance to the last remaining monotherapy, ceftriaxone, in several Asian countries. We examined the AMR of gonococcal isolates obtained…
pubmed
Paopang P, Sangprasert P, Golparian D, Girdthep N 等
2026 Aug 4
置信度 0.82
-
Schistosomiasis japonica is a parasitic disease leading to liver cirrhosis. China's "fishermen going ashore" policy divides patients with schistosomiasis liver fibrosis into two groups: those near the infected waters and those inland far from the infected wate…
pubmed
Fan X, Zhou C, Zhang P, Ming Y
2026 Aug
置信度 0.82
-
HLA-C*07:1268 differs from HLA-C*07:02:01:01 by one nucleotide substitution in exon 3.
pubmed
Siegel RJ, Hacke K, Gebhart CL, Franz BJ 等
2026 Aug
置信度 0.82
-
HLA-B*38:136 differs from HLA-B*38:01:01:01 by a non-synonymous substitution in exon 3.
pubmed
Machado EFG, Linhares JA, Dugonski ME, Cazarote HB 等
2026 Aug
置信度 0.82
-
HLA-C*12:475 differs from HLA-C*12:03:01:01 by a nonsynonymous substitution in exon 1.
pubmed
Machado EFG, Linhares JA, Dugonski ME, Cazarote HB 等
2026 Aug
置信度 0.82
-
Satellite DNA has long posed challenges for genome assembly and analysis due to its low sequence complexity and poor mappability. These large heterochromatic arrays of tandem repeats are ubiquitous across eukaryotic genomes, yet remain understudied. Current me…
pubmed
Sweeten A, Schatz MC, Phillippy AM
2026 Aug 4
置信度 0.82
-
The objective of this study was to investigate the clinical features and genetic variation of a patient with monogenic nonsyndromic obesity caused by melanocortin 4 receptor (MC4R) gene variation. Additionally, this study aims to provide a reference for the di…
pubmed
Li X, Wang X, Liu X, Wang S 等
2026 Aug
置信度 0.82
-
CRISPR-Cas nucleases have revolutionized diagnostics and biotechnology by providing programmable specificity. Here, we extend the understanding of Cas12a biology with a screen that, unexpectedly, finds that Cas12a trans-cleavage activity can be modulated by ni…
pubmed
Iwe IA, Liu FX, Corsano A, da Silva SJR 等
2026 Jul 17
置信度 0.82
-
Genome reduction is widely used to improve microbial bioprocessing hosts by reducing the burden of inessential physiology. Rationally identifying genomic regions that are dispensable or even detrimental to bioprocessing is challenged by our inability to map ge…
pubmed
Fulk EM, Swart RM, Nakamura AK, Quinto LB 等
2026 Jul 17
置信度 0.82
-
Myeloid/lymphoid neoplasms with tyrosine kinase fusions are rare but important because many are highly sensitive to targeted therapy. PDGFRB rearrangements are well-established drivers, whereas TPM3 is an exceptionally rare fusion partner.
pubmed
Lambert F, Koopmansch B, Carazo RF, Dardenne E 等
2026 Aug 4
置信度 0.82
-
While immunotherapy has emerged as a promising treatment option, no reliable predictive biomarker has been established for immunotherapy in hepatocellular carcinoma (HCC). In this study, we used genetic analyses to verify the prognostic significance of tumor m…
pubmed
Lee J, Lee HW, Park MR, Shin S 等
2026 Jun 16
置信度 0.82
-
A streamlined, sensitive, and universal molecular method for MRD detection in pediatric AML remains an unmet clinical need. Here, we propose a novel approach based on tracking somatic non-coding passenger variants. Using whole-genome sequencing (WGS) of diagno…
pubmed
Shiloh R, Dayan D, Geron I, Cohen M 等
2026 Aug
置信度 0.82
-
Smith-Kingsmore syndrome is a rare neurodevelopmental disorder that is caused by somatic variants in the MTOR gene. The present study reports on a monozygotic twin exhibiting hypomelanosis of Ito and localized brain overgrowth, attributable to a complex somati…
pubmed
Karaca NB, Ceylaner S, Yeniay Süt N, Alıcı N 等
2026 Jun 16
置信度 0.82
-
The complete chloroplast genome of Amorphophallus josefbogneri Hett 2006 was sequenced, assembled, and annotated. The genome is 172,957 bp in length and exhibits a typical circular quadripartite structure with LSC 94,009 bp, SSC 14,946Ȁ…
pubmed
Shi H, Wang W, Chen K, Qi Y 等
2026
置信度 0.82
-
We have collected the bacterial communities inhabiting the rhizosphere and seed-surface of selected crop plants ('Panchabrihi' rice, soybean, and bean) in Bangladesh and created a draft genome assembly database of the isolated bacterial strains. Three bacteria…
pubmed
Sultana N, Chaudhury A, Farheen S
2026 Aug
置信度 0.82
-
Chloroplast genomes are widely used in phylogenetic and evolutionary studies due to their conserved structure and maternal inheritance. However, a comprehensive pan-chloroplast analysis across the genus Hordeum remains lacking. In this study, we assembled and …
pubmed
Du Q, Zhang Z, Li R
2026
置信度 0.82
-
A multi-locus DNA barcode reference library was developed for 55 medicinal plant species from the 56 collected in the United Arab Emirates using rbcL , matK , and ITS2 markers, generating 397 high-quality sequences from 146 specimens. The rbcL marker showed th…
pubmed
Jamdade R, Al Jasmi M, Alsallani M, Al Shaer K 等
2026 Aug
置信度 0.82
-
pubmed
Oh J, Lee K, Won D, Lee YM 等
2026 Aug 4
置信度 0.82
-
The Black Tiger Shrimp ( Penaeus monodon ) is one of the world's most valuable aquaculture resources, and its genetic diversity has been measured through the Indo-Pacific region. We examined variation in a 584 bp region of mtDNA Cytochrome Oxidase Subunit I (C…
pubmed
Alam MMM, Westfall K, Palsson S
2026
置信度 0.82
-
HLA-C*06:02:01:117 differs from HLA-C*06:02:01:01 by single nucleotide change in the 5'UTR at position gDNA -149.
pubmed
Karale B, Tambe M, Rajak J, D'Silva SZ
2026 Aug
置信度 0.82
-
HLA-A*33:03:01:32 and HLA-C*04:01:01:205 differ from HLA-A*33:03:01:01 and HLA-C*04:01:01:01 by a single nucleotides within introns respectively.
pubmed
Karale B, Tambe M, Rajak J, D'Silva SZ
2026 Aug
置信度 0.82
-
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