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2026-07-06T19:05:38Z
置信度 0.70
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crossref
2021-11-29T15:05:11Z
置信度 0.70
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Post-translational modification such as N-Glycosylation on biologics during the production of monoclonal antibody (mAb) based therapeutics is a critical quality attribute that dictates safety and efficacy. Variability is introduced in the cell culture process …
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Erin Tiwold, Aron Gyorgypal, Shishir Chundawat
2022-04-13T01:31:57Z
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Marc Bisschops, Andreas Castan, Britta Manser, Xènia Massana-Munoz
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Zhang-He Goh
2020-02-18T08:07:12Z
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Juan Cruz Casabona
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Sanjiv Sonkaria, Varsha Khare
2020-04-01T16:02:46Z
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Aleksander Skardal
2018-08-17T13:40:34Z
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2012-01-24T17:15:54Z
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2026-02-03T19:40:56Z
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2022-10-24T09:05:44Z
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2015-09-25T16:32:13Z
置信度 0.70
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Jagat Bhushan, Vishakha Grover
2019-03-20T13:40:33Z
置信度 0.70
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Beyond microbial fermentation: Reimagining biomanufacturing for low-resource environments Although traditional biomanufacturing is based on microbial or mammalian cell culture, plants can be grown in bioreactors and hold enormous promise for use in resource-li…
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Karen A. McDonald
2026-01-21T11:08:04Z
置信度 0.70
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2026-06-24T12:20:19Z
置信度 0.70
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Shawna Pandya
2025-01-31T21:06:47Z
置信度 0.70
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Jason Beckwith
2026-07-06T18:37:49Z
置信度 0.70
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Axel Schmidt, Alina Hengelbrock, Jochen Strube
2024-06-18T04:43:06Z
置信度 0.70
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Homare Tabata
2012-02-20T12:58:22Z
置信度 0.70
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Abstract The success of the da Vinci system has shown the feasibility and a great potential of using robotic systems to improve healthcare. With a trend of replacing more and more invasive surgeries with minimally invasive interventional procedures, developing…
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Yang Liu, Dian-Ru Li
2023-09-28T21:39:48Z
置信度 0.70
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2024-03-19T17:15:04Z
置信度 0.70
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2024-03-19T17:15:04Z
置信度 0.70
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Gareth John Macdonald
2020-08-05T07:11:10Z
置信度 0.70
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2024-03-19T17:15:04Z
置信度 0.70
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2026-06-03T09:50:49Z
置信度 0.70
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Azan Ali, Mohammad Usman, Elammaran Jayamani, KokHeng Soon 等
2023-12-14T11:59:16Z
置信度 0.70
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A bioreactor is a specialized vessel designed to facilitate biological reactions, harnessing the capabilities of microorganisms, mammalian cells, or other biological systems to convert raw materials into valuable products. Bioreactor systems serve as the centr…
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Rishabh Garg, Ayush Madan
2025-09-30T19:26:24Z
置信度 0.70
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2024-12-24T12:23:01Z
置信度 0.70
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Alok Kumar Srivastav, Priyanka Das
2025-08-02T13:03:22Z
置信度 0.70
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Abdul Wasy Zia
2019-03-20T17:40:33Z
置信度 0.70
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Albert Flavier, Fatima Merchant
2026-04-16T16:42:15Z
置信度 0.70
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crossref
2024-03-19T17:15:04Z
置信度 0.70
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crossref
2022-10-24T09:05:44Z
置信度 0.70
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Polymers have a major contribution to make in the field of regenerative medicine in order to develop and deploy biological substitutes that restore, maintain, or improve tissue function. There are realistic opportunities to create tissues using an engineered e…
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G.R. Mitchell, M. Domingos, Paulo J. Bartolo
2012-06-06T12:20:44Z
置信度 0.70
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This report estimates biomanufacturing (manufactured products made of biomaterials) and advanced biomanufacturing (products manufactured using activities that grow biological molecules and materials along with activities that alter biological material using no…
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Douglas Thomas
2023-06-09T13:39:36Z
置信度 0.70
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Xuecheng Lin, Lan Wang, Hongzhang Chen
2025-07-14T03:16:47Z
置信度 0.70
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Michael Scott Rafuse, David Madukwe, Richard D. Johnson, Wei Tan
2025-10-21T11:26:35Z
置信度 0.70
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2022-10-24T09:05:44Z
置信度 0.70
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crossref
Jason Walther
2025-05-21T05:53:41Z
置信度 0.70
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Commercial production of therapeutic proteins using mammalian cells requires complex process solutions, and consistency of these process solutions is critical to maintaining product titer and quality between batches. Inconsistencies between process solutions p…
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Timothy Brantley, Brandon Moore, Chris Grinnell, Sarwat Khattak
2021-04-03T14:07:40Z
置信度 0.70
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crossref
2023-09-29T09:57:42Z
置信度 0.70
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ABSTRACT While rising greenhouse gases cause climate change, global economies ask for resilient solutions for the business of the future. Biomanufacturing may well serve as a pillar of a circular economy with minimised environmental impact. Therefore, innovati…
europepmc
Ralf Takors
2025
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Cristina Peixoto, Otto‐Wilhelm Merten
2021-01-13T07:59:26Z
置信度 0.70
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Jason Beckwith
2026-07-06T18:37:49Z
置信度 0.70
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2024-03-19T17:15:04Z
置信度 0.70
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Sunil Martin
2022-12-20T11:26:10Z
置信度 0.70
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2022-01-03T14:45:14Z
置信度 0.70
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Santosh Kumar Mishra, Indu Bhatt, Prabir Kumar Paul
2023-01-26T17:03:48Z
置信度 0.70
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crossref
Rina D. Koyani
2019-09-30T23:30:48Z
置信度 0.70
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Abstract A majority of the biotherapeutics industry today relies on the manufacturing of monoclonal antibodies from Chinese hamster ovary (CHO) cells, yet challenges remain with maintaining consistent product quality from high‐producing cell lines. Previous st…
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Ashli Polanco, George Liang, SoYoung Park, Yongdan Wang 等
2023-07-27T08:32:47Z
置信度 0.70
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crossref
James N. Warnock
2024-01-10T05:02:16Z
置信度 0.70
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Jeff Carter, Genine Dale, Michael DiFiore, Audra Matthews 等
2020-09-13T21:28:13Z
置信度 0.70
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crossref
2014-01-21T06:34:25Z
置信度 0.70
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Chemistry and biotechnology played a central role in transforming a poverty-stricken region in the middle of Europe into a flourishing industrial country. Rural areas remained destitute well into the 18th century. However, during the second half of the 18th ce…
europepmc
Michael Altorfer, Jan M. Lucht, Hans-Peter Meyer
2025
置信度 0.80
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Paint shop is the biggest energy consumer in automotive manufacturing plant. Large amount of conditioned air, which leads to a high energy demand, is one of the basic demands in guaranteeing high quality product and a comfortable working environment. A good de…
crossref
Lujia Feng, Laine Mears
2015-09-25T16:32:13Z
置信度 0.70
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With rapid innovation in the electronics industry, product obsolescence forecasting has become increasingly important. More accurate obsolescence forecasting would have cost reduction effects in product design and part procurement over a product’s lifetime. Cu…
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Connor Jennings, Dazhong Wu, Janis Terpenny
2016-09-27T13:39:10Z
置信度 0.70
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crossref
Khalisanni Khalid, Shir Reen Chia, Kit Wayne Chew, Pau Loke Show
2021-05-08T21:57:53Z
置信度 0.70
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Biopharmaceutical production is an important industry for the production of life-saving biologics such as monoclonal antibodies, recombinant proteins, and vaccines. Nevertheless, the industry is plagued by serious issues of process efficiency, scalability, reg…
crossref
Mukul Machhindra Barwant, Balwant Singh, Amir M. Vazirizadeh
2025-09-30T19:26:24Z
置信度 0.70
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Microbe development for the biomanufacturing age Joe Price, Dr Kang Lan Tee & Prof Tuck Seng Wong, explore adopting a holistic approach to microbe development for the age of biomanufacturing. Since the late 2000s, scientists worldwide have proposed that hu…
crossref
Joe Price, Tuck Seng Wong, Kang Lan Tee
2024-01-24T14:20:53Z
置信度 0.70
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crossref
Xuecheng Lin, Lan Wang, Hongzhang Chen
2025-07-29T06:28:11Z
置信度 0.70
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Michelangelo Canzoneri, Marc Horner, Prith Banerjee
2024-08-28T19:02:52Z
置信度 0.70
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Abhishek Kumar Tiwari, Jitendra Prasad
2019-03-20T17:40:33Z
置信度 0.70
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M.W. Jornitz, J.-M. Cappia, G. Rao
2021-05-10T14:46:15Z
置信度 0.70
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crossref
Ivan Martin, Elia Piccinini, David Wendt
2010-08-13T10:43:17Z
置信度 0.70
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crossref
Jaya Tripathi, Nawa Raj Baral, Eric Sundstrom, Corinne D. Scown
2025-06-17T02:38:27Z
置信度 0.70
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crossref
2024-03-19T17:15:04Z
置信度 0.70
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crossref
2009-05-13T18:14:20Z
置信度 0.70
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crossref
William G. Whitford
2021-12-24T22:18:31Z
置信度 0.70
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crossref
Jason Beckwith
2026-07-06T18:37:49Z
置信度 0.70
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To address the latest challenges in the service-oriented manufacturing paradigm, cloud manufacturing is proposed for not just large-scale enterprises, but also small- and medium-sized enterprises (SMEs). Although enterprises acknowledge its technical merits, m…
crossref
Yijing Wang, Tao Peng
2016-09-27T13:39:10Z
置信度 0.70
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crossref
Todd C. McDevitt
2014-06-12T04:07:14Z
置信度 0.70
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crossref
2019-12-03T15:04:04Z
置信度 0.70
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crossref
Chen Kan, Ruimin Chen, Hui Yang
2017-07-21T15:44:21Z
置信度 0.70
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crossref
2024-11-15T11:00:31Z
置信度 0.70
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crossref
2019-12-03T15:04:04Z
置信度 0.70
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crossref
Jason Beckwith
2026-07-06T18:37:49Z
置信度 0.70
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Abstract This chapter provides a brief introduction to biopharmaceutical manufacturing covering the essential elements of the overall manufacturing enterprise. Because of the complexity of biopharmaceuticals, the manufacturing facility must be designed with a …
crossref
Mark F. Witcher
2014-09-15T06:35:11Z
置信度 0.70
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Evolution of crystallographic textures in sand blasted surfaces is studied. Sand blasting is approximated as a series of ideal cylindrical, flat punch and wedge indents. Features of the deformation field produced during indentation with these geometries is stu…
crossref
Saurabh Basu, Zhiyu Wang, Christopher Saldana
2015-09-25T16:32:13Z
置信度 0.70
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crossref
Zizhao Wu, Peng Xu
2025-05-23T15:02:27Z
置信度 0.70
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crossref
Yanghai Luo, Yao Song, Hui Xu, Yi Cao
2026-08-24T06:59:11Z
置信度 0.70
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crossref
Beenish Saba, Ann Christy, Thaddeus C. Ezeji, Katrnia Cornish 等
2025-02-07T22:36:45Z
置信度 0.70
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crossref
A. Mellott
2026-04-30T22:05:21Z
置信度 0.70
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crossref
P.R. Sreeraj, Santosh Kr. Mishra
2023-01-19T20:58:45Z
置信度 0.70
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crossref
2016-12-16T21:19:17Z
置信度 0.70
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crossref
2019-12-03T10:04:04Z
置信度 0.70
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crossref
André Pastor, Stéphan Barbe
2011-06-25T05:47:52Z
置信度 0.70
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crossref
Britta Manser, Martin Glenz
2021-12-24T22:18:31Z
置信度 0.70
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crossref
Jae-Llane Ditchburn, Carlos Brais Carballeira
2019-04-23T11:51:52Z
置信度 0.70
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ABSTRACT Conventional biomanufacturing faces critical translational bottlenecks, including limited clinical availability of functional tissues, inability to achieve long‐term storage, and structural collapse during large‐scale fabrication. Cryogenic biomanufac…
crossref
Kerui Zhou, Wei Rao
2026-06-06T10:27:02Z
置信度 0.70
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crossref
Rachna Shashikant Jadhav, Saurabh Kulshrestha, Himanshu Sharma, Santanu Mukherjee
2026-07-08T15:04:58Z
置信度 0.70
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crossref
Xiaojun Lian, Sean P. Palecek
2012-05-25T18:59:06Z
置信度 0.70
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Interest in additive manufacturing has recently been spurred by the promise of multi-material printing and the ability to embed functionality and intelligence into objects. Here, we present an alternative to additive manufacturing, introducing an end-to-end wo…
crossref
Will Langford, Amanda Ghassaei, Neil Gershenfeld
2016-09-27T13:39:10Z
置信度 0.70
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crossref
Alberto T. Estévez, Diego Navarro
2017-09-26T15:15:59Z
置信度 0.70
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crossref
Anup Malik, Alakesh Manna, Chander Prakash, Sunpreet Singh
2019-03-20T13:40:33Z
置信度 0.70
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crossref
Frank Westwood, Michael Ponstingl, Jason Dickens
2023-11-17T02:55:08Z
置信度 0.70
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crossref
Jason Beckwith
2026-07-06T18:37:49Z
置信度 0.70
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crossref
Saroj Raj Kafle, Anirudh Mukunth, Arum Han, Arul Jayaraman 等
2025-12-04T18:42:47Z
置信度 0.70
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crossref
2025-10-22T03:20:23Z
置信度 0.70
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Fungal-host coevolution, intensified by climate change, is attracting greater efforts to characterize new virulence proteins to enable the protection of agricultural crops. Under PRISMA guidelines, in this systematic review we analyzed 122 experimental studies…
pubmed
de Oliveira HVV, de Rezende DCB, Porto JAM, Aguiar ERGR 等
2026 Jul 24
置信度 0.82
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Agriculture faces significant limitations from climate change, soil degradation, and a wide range of abiotic and biotic stresses that continually threaten global food security. Although transcriptional and hormonal regulatory networks have been extensively stu…
pubmed
Manda T, Hwarari D, Dzinyela R
2026 Jul 24
置信度 0.82