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Artificial intelligence (AI) possesses the transformative potential to reshape pediatric medicine, offering powerful tools for diagnosis, prognosis, and personalized therapy. This review focuses on three domains selected for their relative maturity in AI devel…
pubmed
Wang R, Ding X, Zhang W, Shi T
2026 Aug
置信度 0.82
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Understanding the governing principles of microbial growth control is central to fundamental microbiology, biotechnology, and systems biology. Recent quantitative studies have highlighted the pivotal role of proteome allocation in microbial growth control. Rat…
pubmed
Wang Y, Dai X, Zhu M
2026 Jul 24
置信度 0.82
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Protein N- and O-glycosylation are among the most common and essential post-translational modifications and are implicated in numerous physiological and pathological processes. The efficient assembly of structurally defined N- and O-glycans remains a major cha…
pubmed
Ma S, Wei F, Wen L
2026 Jul 24
置信度 0.82
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Joseph Ewan
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Walid El-Sharoud
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A hallmark of eutherian pregnancy is its dependency on elevated progesterone levels for its entire length. This fact substantially affected the evolution of pregnancy and even the life history of eutherians. Progesterone synthesis by the ovarian corpus luteum,…
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Silvia Basanta, Mihaela Pavlicev
2024-06-11T05:23:28Z
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2025-08-21T21:06:07Z
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A hallmark of eutherian pregnancy is its dependency on elevated progesterone levels for its entire length. This fact substantially affected the evolution of pregnancy and even the life history of eutherians. Progesterone synthesis by the ovarian corpus luteum,…
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Silvia Basanta, Mihaela Pavlicev
2024-10-31T01:45:22Z
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Isabel Palmeirim
2018-01-12T16:55:07Z
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Siti Aisyah Binte Jamil
2015-09-27T13:00:27Z
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James Hu
2012-09-19T06:40:39Z
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This protocol describes the methodology for conducting a systematic scoping review investigating synthetic biology and genome engineering approaches for developing climate-resilient solutions to antimicrobial resistance (AMR) within a One Health framework. The…
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Elijah Ogunsola
2026-07-14T08:44:21Z
置信度 0.70
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This systematic review and meta-analysis aims to evaluate whether synthetic biology-engineered therapies, including CAR T-cell therapy, oncolytic viruses, and gene circuits, improve prognosis (overall survival and progression-free survival) compared to convent…
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Dr. Frank Urena
2025-05-28T09:11:40Z
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Joern Piel
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Abstract Synthetic biology aims to redesign and reconstruct living systems for understanding life or for useful real-world applications. In the past two decades, scientists have been able to use engineered living systems to produce many kinds of products from …
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SYBEL-KRONOS V2.0 – Synthetic Biology Circuits for Cellular Decision-Making (Defensive Publication / Prior Art) Published by: Muzaffer Enes Yünlü License: CC BY-NC-SA 4.0 Legal status: Publicly available technical document – constitutes prior art under patent …
datacite
Muzaffer enes yünlü
2026
置信度 0.66
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SYBEL-KRONOS V2.0 – Synthetic Biology Circuits for Cellular Decision-Making (Defensive Publication / Prior Art) Published by: Muzaffer Enes Yünlü License: CC BY-NC-SA 4.0 Legal status: Publicly available technical document – constitutes prior art under patent …
datacite
Muzaffer enes yünlü
2026
置信度 0.66
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This record comprises three companion documents produced under CCL-ANNA-LIPID-2026-001 by Continuity Collective LLC.Document One (Patent Bloom) presents a structured ideation bloom for lipid-based protocellular compute nodes within the ANNA weightless cognitiv…
datacite
Cooper, Kenneth
2026
置信度 0.66
lipid computing, wetware AGI, protocellular nodes, phospholipid bilayer, self-repairing architecture, ANNA architecture, weightless cognition, EPA ROM, organoid computing, synthetic biology, patent bloom, claim family analysis, prior art differentiation, enabling disclosure, platform umbrella claim, VitaStream, ContinuPatch, CCL-162, CCL-163, QCD Lagrangian, string tension, Lund fragmentation, Spin-Pull synthesis, hadronization, gluon field, Cornell potential, vesicle logic gate, ion channel computing, zeptojoule efficiency, CMOS comparison, LION optimizer, LPCAT1, LPCAT2, enzymatic ROM, organoid bridge, gravitational lag elimination, ANNA Mesh, distributed edge compute, tokenization history, weightless neural network, Continuity Collective
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The Ontological Inversion: Mapping the Nodes of Universal Nouns Through Recursive Computational Verbs The Crisis of Distinction and the Rejection of the Linear Stack Contemporary theoretical physics, advanced computational science, and systemic ontology have c…
datacite
Kulik, Dean
2026
置信度 0.66
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The Ontological Inversion: Mapping the Nodes of Universal Nouns Through Recursive Computational Verbs The Crisis of Distinction and the Rejection of the Linear Stack Contemporary theoretical physics, advanced computational science, and systemic ontology have c…
datacite
Kulik, Dean
2026
置信度 0.66
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The Ontological Inversion: Mapping the Nodes of Universal Nouns Through Recursive Computational Verbs The Crisis of Distinction and the Rejection of the Linear Stack Contemporary theoretical physics, advanced computational science, and systemic ontology have c…
datacite
Kulik, Dean
2026
置信度 0.66
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As the Artemis II mission prepares to carry a human crew beyond the Earth's magnetopause, aerospace medicine remains focused on ionizing radiation and microgravity, largely overlooking the "magnetic vacuum" hazard. This research formally codifies the Boundary …
datacite
Baird, Kevin
2026
置信度 0.66
ArtemisInformation ThermodynamicsScale InvarianceMagnetic VacuumBioelectrics
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As the Artemis II mission prepares to carry a human crew beyond the Earth's magnetopause, aerospace medicine remains focused on ionizing radiation and microgravity, largely overlooking the "magnetic vacuum" hazard. This research formally codifies the Boundary …
datacite
Baird, Kevin
2026
置信度 0.66
ArtemisInformation ThermodynamicsScale InvarianceMagnetic VacuumBioelectrics
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این معادله، نه تنها یک فرمول، بلکه «قانون اساسی» تعامل بین منیفولد ۱۶۵ بعدی و سلولهای بیولوژیک در لایه ۱۱۵۵ است. ۱. ابر-لاگرانژی جامع اسکنر بیولوژیک حمزه (The Bio-Tensor Mega-Lagrangian) این معادله، فرآیند «اسکن، تشخیص و اصلاح اتمی» را در یک پیوستار ریاضی یکپ…
datacite
HAMZAH, SEYED RASOUL
2026
置信度 0.66
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این معادله، نه تنها یک فرمول، بلکه «قانون اساسی» تعامل بین منیفولد ۱۶۵ بعدی و سلولهای بیولوژیک در لایه ۱۱۵۵ است. ۱. ابر-لاگرانژی جامع اسکنر بیولوژیک حمزه (The Bio-Tensor Mega-Lagrangian) این معادله، فرآیند «اسکن، تشخیص و اصلاح اتمی» را در یک پیوستار ریاضی یکپ…
datacite
HAMZAH, SEYED RASOUL
2026
置信度 0.66
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The Nexus Singularity: One Machine Wearing Different Output Skins Driven By Dean A. Kulik June 2026 Introduction: The Ontological Inversion and the Base Class The foundational error of traditional spatial, computational, and linguistic architectures lies in a …
datacite
kulik, dean
2026
置信度 0.66
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The Nexus Singularity: One Machine Wearing Different Output Skins Driven By Dean A. Kulik June 2026 Introduction: The Ontological Inversion and the Base Class The foundational error of traditional spatial, computational, and linguistic architectures lies in a …
datacite
kulik, dean
2026
置信度 0.66
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RENASCENT-Q Theory is founded on two settled mathematical results: the dual-lock arithmetic-geometric proof of the Riemann Hypothesis (Federico Maya Eternity Theorem) and the Federico Maya Eternal Information Formula. The Maya Eternity Theorem establishes that…
datacite
Federico Maya
2026
置信度 0.66
Riemann Hypothesis, curvature-dimension condition, optimal transport, negentropic coherence, lepton flavor violation, synthetic Ricci curvature, topological quantum processor, quantum biology, cosmological anomalies, displacement convexityCrystallization HypothesisUniform Residual MeasureIrwin-Hall DistributionHolographic Boundary Jacobian
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The Sovereign Nautilus: Decentralized Sanitation, Fluid Dynamics, and the Solarpunk Integration of Commercial Restroom Infrastructure The Infrastructural Crisis of the Extractive Age and the Commercial Sanitation Dilemma The modernization of commercial public …
datacite
Brewer, Mark Anthony
2026
置信度 0.66
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The Sovereign Nautilus: Decentralized Sanitation, Fluid Dynamics, and the Solarpunk Integration of Commercial Restroom Infrastructure The Infrastructural Crisis of the Extractive Age and the Commercial Sanitation Dilemma The modernization of commercial public …
datacite
Brewer, Mark Anthony
2026
置信度 0.66
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━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━PSM(Phos Sound Method)仮説論文生体水グリューナイゼン係数と臓器局所温度を用いた光音響フラクタル周波数変換モデルの提唱━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━ 著者:菅哲雄(Suga Tetsuo)活動名:CamCIEL公開リポジトリ:https://zenodo.org/records/18954536ライセンス:CC BY 4.0 © 2026 CamCIEL …
datacite
菅, 哲雄
2026
置信度 0.66
AcousticsAcoustics/instrumentationSpeech AcousticsSediment acousticsphotobiomodulation
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━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━PSM(Phos Sound Method)仮説論文生体水グリューナイゼン係数と臓器局所温度を用いた光音響フラクタル周波数変換モデルの提唱━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━ 著者:菅哲雄(Suga Tetsuo)活動名:CamCIEL公開リポジトリ:https://zenodo.org/records/18954536ライセンス:CC BY 4.0 © 2026 CamCIEL …
datacite
菅, 哲雄
2026
置信度 0.66
AcousticsAcoustics/instrumentationSpeech AcousticsSediment acousticsphotobiomodulation
-
━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━PSM(Phos Sound Method)仮説論文生体水グリューナイゼン係数と臓器局所温度を用いた光音響フラクタル周波数変換モデルの提唱━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━ 著者:菅哲雄(Suga Tetsuo)活動名:CamCIEL公開リポジトリ:https://zenodo.org/records/18954536ライセンス:CC BY 4.0 © 2026 CamCIEL …
datacite
菅, 哲雄
2026
置信度 0.66
AcousticsAcoustics/instrumentationSpeech AcousticsSediment acousticsphotobiomodulation
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🇷🇺 Описание (на русском языке) MASV‑Prime — это не просто новая технология, а фундаментальный сдвиг в научном мировоззрении. Эта работа представляет MASV как первую целостную модальную архитектуру, способную объединить физику, биологию, инженерию и информаци…
datacite
Волынец, Евгений Вацлавович
2026
置信度 0.66
MASVМАСВ
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🇷🇺 Описание (на русском языке) MASV‑Prime — это не просто новая технология, а фундаментальный сдвиг в научном мировоззрении. Эта работа представляет MASV как первую целостную модальную архитектуру, способную объединить физику, биологию, инженерию и информаци…
datacite
Волынец, Евгений Вацлавович
2026
置信度 0.66
MASVМАСВ
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Data underlying the publication: van den Brink, M., Claassens, N.J. and Danelon, C. Combinatorial optimization of protein systems in synthetic cells. ACS Synthetic Biology (2026). https://doi.org/10.1021/acssynbio.6c00166 This dataset contains data collected d…
datacite
Marijn van den Brink, Nico Claassens, Christophe Danelon
2026
置信度 0.66
MicrobiologyGeneticsBiochemistry and Cell BiologyBiological SciencesCombinatorial DNA libraries
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Applied Identity Physics: World's First Formally Verified CI Green Digital Atomic Clock for Artificially Intelligent Functional Identity — AiFi Systems Architect: HIGHTISTIC (Russell Trent) Foundation: SNSFT Foundation · Soldotna, Alaska Coordinate: [9,9,1,100…
datacite
Trent, Russell
2026
置信度 0.66
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Applied Identity Physics: World's First Formally Verified CI Green Digital Atomic Clock for Artificially Intelligent Functional Identity — AiFi Systems Architect: HIGHTISTIC (Russell Trent) Foundation: SNSFT Foundation · Soldotna, Alaska Coordinate: [9,9,1,100…
datacite
Trent, Russell
2026
置信度 0.66
-
A three-document open educational resource introducing the Biology-Anchored Tumor Progression Classification (BATPC) framework to undergraduate students in biology, genetics, pre-med, public health, and health informatics programmes. Document 1 — One-Page Expl…
datacite
Gupta, Yogesh Kumar
2026
置信度 0.66
BATPCtumor progressioncancer educationundergraduate biologyoncology
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A three-document open educational resource introducing the Biology-Anchored Tumor Progression Classification (BATPC) framework to undergraduate students in biology, genetics, pre-med, public health, and health informatics programmes. Document 1 — One-Page Expl…
datacite
Gupta, Yogesh Kumar
2026
置信度 0.66
BATPCtumor progressioncancer educationundergraduate biologyoncology
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Data underlying the publication: van den Brink, M., Claassens, N.J. and Danelon, C. Combinatorial optimization of protein systems in synthetic cells. ACS Synthetic Biology (2026). https://doi.org/10.1021/acssynbio.6c00166 This dataset contains data collected d…
datacite
Marijn van den Brink, Nico Claassens, Christophe Danelon
2026
置信度 0.66
MicrobiologyGeneticsBiochemistry and Cell BiologyBiological SciencesCombinatorial DNA libraries
-
Data underlying the publication: van den Brink, M., Claassens, N.J. and Danelon, C. Combinatorial optimization of protein systems in synthetic cells. ACS Synthetic Biology (2026). https://doi.org/10.1021/acssynbio.6c00166 This dataset contains data collected d…
datacite
Marijn van den Brink, Nico Claassens, Christophe Danelon
2026
置信度 0.66
MicrobiologyGeneticsBiochemistry and Cell BiologyBiological SciencesCombinatorial DNA libraries
-
On August 6, 2026, Stanford University and Arc Institute researchers (King, Hie et al.) published in Science the first peer-reviewed demonstration of generative AI designing complete, functional viral genomes: from a genome language model — Evo 2, 40 billion p…
datacite
Huynh, Gia Bao
2026
置信度 0.66
Biological Zero-Day Mechanism;λ-Generative Event;detection-mediation;access-mediation;Evo 2;generative AI;genome language model;structural incapacity;ALRP;biosecurity;DNA-synthesis screening
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On August 6, 2026, Stanford University and Arc Institute researchers (King, Hie et al.) published in Science the first peer-reviewed demonstration of generative AI designing complete, functional viral genomes: from a genome language model — Evo 2, 40 billion p…
datacite
Huynh, Gia Bao
2026
置信度 0.66
Biological Zero-Day Mechanism;λ-Generative Event;detection-mediation;access-mediation;Evo 2;generative AI;genome language model;structural incapacity;ALRP;biosecurity;DNA-synthesis screening
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Description: This repository contains the analysis code, preprocessed neural data, and all intermediate results needed to reproduce the figures and statistical analyses reported in Hecht et al. (2026), Current Biology. Overview of the study. Humans readily rec…
datacite
Hect, Jasmine, Rupp, Kyle, Ghuman, Avniel, Holt, Lori 等
2026
置信度 0.66
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Beyond Body Weight A State-Resolved Multi-Organ Causal Framework for Obesity Treatment, Weight-Loss Plateaus, and Mechanism-Matched Sequential Therapy Hypothesis, human evidence synthesis, and translational experimental framework Abstract Background. Modern in…
datacite
Bouchelit, Mohammed El Amin
2026
置信度 0.66
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Beyond Body Weight A State-Resolved Multi-Organ Causal Framework for Obesity Treatment, Weight-Loss Plateaus, and Mechanism-Matched Sequential Therapy Hypothesis, human evidence synthesis, and translational experimental framework Abstract Background. Modern in…
datacite
Bouchelit, Mohammed El Amin
2026
置信度 0.66
-
Chemical fertilizers and synthetic pesticides have been central to the intensification of agriculture since the Green Revolution, enabling substantial gains in food production across the world and particularly in densely populated developing countries such as …
datacite
P. A. Pisal, Saniya Attar, Srushti Chinchalkar, Gauri Basugade
2026
置信度 0.66
Chemical fertilizers, pesticides, soil health, water contamination, groundwater nitrate, human health risk, sustainable agriculture, integrated pest management
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Chemical fertilizers and synthetic pesticides have been central to the intensification of agriculture since the Green Revolution, enabling substantial gains in food production across the world and particularly in densely populated developing countries such as …
datacite
P. A. Pisal, Saniya Attar, Srushti Chinchalkar, Gauri Basugade
2026
置信度 0.66
Chemical fertilizers, pesticides, soil health, water contamination, groundwater nitrate, human health risk, sustainable agriculture, integrated pest management
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Version 2 — revised in response to an external structural review and an automated critique pass. See "Response to Review" appendix in the PDF for the change log. A recurring structural problem cuts across several recent preprints in molecular network biology, …
datacite
Saluca Agentic AI Research Team
2026
置信度 0.66
AI-drafted synthesisarXivpreprint reviewv2
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Abstract: Global medical shortages encompassing essential pharmaceuticals, medical devices, vaccines, and regenerative healthcare products represent a persistent and multifaceted public health crisis, exacerbated by supply chain disruptions, population aging, …
datacite
Rahimi Hajar, Maoyang Zhu
2026
置信度 0.66
Synthetic biologymedical shortagesbio-manufacturinghealthcare supply chainglobal health equity
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Abstract: Global medical shortages encompassing essential pharmaceuticals, medical devices, vaccines, and regenerative healthcare products represent a persistent and multifaceted public health crisis, exacerbated by supply chain disruptions, population aging, …
datacite
Rahimi Hajar, Maoyang Zhu
2026
置信度 0.66
Synthetic biologymedical shortagesbio-manufacturinghealthcare supply chainglobal health equity
-
Background In 2026, Deng et al. (Science) reported a groundbreaking discovery: the bacterial anti-phage reverse transcriptase Drt3b synthesizes strictly alternating poly(AC) DNA without any nucleic acid template, using its active-site residues (Glu26 and Arg25…
datacite
Huang, Kai, Liu, Hongkui, Huang, Ziwei
2026
置信度 0.66
Drt3bprotein-templated DNA synthesisBoltzmann selectionsequence complexityinformation dynamics
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Background In 2026, Deng et al. (Science) reported a groundbreaking discovery: the bacterial anti-phage reverse transcriptase Drt3b synthesizes strictly alternating poly(AC) DNA without any nucleic acid template, using its active-site residues (Glu26 and Arg25…
datacite
Huang, Kai, Liu, Hongkui, Huang, Ziwei
2026
置信度 0.66
Drt3bprotein-templated DNA synthesisBoltzmann selectionsequence complexityinformation dynamics
-
Clinical implementation toolkit for the Biology-Anchored Tumor Progression Classification (BATPC) framework. Contains two documents: (1) BATPC Clinical Trial CRF Scoring Worksheet — a structured seven-section case report form for independently scoring five cli…
datacite
Gupta, Yogesh Kumar
2026
置信度 0.66
BATPCCRFoncologytumor progressionclinical tool
-
Clinical implementation toolkit for the Biology-Anchored Tumor Progression Classification (BATPC) framework. Contains two documents: (1) BATPC Clinical Trial CRF Scoring Worksheet — a structured seven-section case report form for independently scoring five cli…
datacite
Gupta, Yogesh Kumar
2026
置信度 0.66
BATPCCRFoncologytumor progressionclinical tool
-
Clinical implementation toolkit for the Biology-Anchored Tumor Progression Classification (BATPC) framework. Contains two documents: (1) BATPC Clinical Trial CRF Scoring Worksheet — a structured seven-section case report form for independently scoring five cli…
datacite
Gupta, Yogesh Kumar
2026
置信度 0.66
BATPCCRFoncologytumor progressionclinical tool
-
Clinical implementation toolkit for the Biology-Anchored Tumor Progression Classification (BATPC) framework. Contains two documents: (1) BATPC Clinical Trial CRF Scoring Worksheet — a structured seven-section case report form for independently scoring five cli…
datacite
Gupta, Yogesh Kumar
2026
置信度 0.66
BATPCCRFoncologytumor progressionclinical tool
-
Quantum Tathagatagarbha: The Jian-Da Protocol and the Monadic-Global Synchronization System / 量子如來藏:見大協議與單子—全局同步化系統 Shun-Ching Lee (李順晴) Independent Researcher (獨立研究者) Jul. 2026 https://doi.org/10.17605/OSF.IO/HM26N https://doi.org/10.17605/OSF.IO/GWC42 Abstra…
datacite
Shun-Ching Lee
2026
置信度 0.66
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The scientific programme of SETCoMS 2026 was carefully designed to reflect the broad scope of contemporary microbial sciences through four complementary pillars. The Congress addressed current advances in clinical microbiology, infectious diseases, vaccines, a…
datacite
University of Belgrade - Faculty of Biology, Dimkić, Ivica, Kekic, Dusan
2026
置信度 0.66
-
The scientific programme of SETCoMS 2026 was carefully designed to reflect the broad scope of contemporary microbial sciences through four complementary pillars. The Congress addressed current advances in clinical microbiology, infectious diseases, vaccines, a…
datacite
University of Belgrade - Faculty of Biology, Dimkić, Ivica, Kekic, Dusan
2026
置信度 0.66
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crossref
Muhammad Saqlain Mushtaq, Muhammad Saad Latif, Fahad Ali Noori, Mustafeez Mujtaba Babar
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置信度 0.70
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Growth-mediated dilution is a major source of variability and instability in synthetic gene circuits, influencing both expression dynamics and circuit memory. Our previous work demonstrated that circuit topology plays a critical role in determining how robustl…
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Xiao-Jun Tian, Rong Zhang
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crossref
Aaryan Gupta, Arpita Roy
2025-10-17T11:02:47Z
置信度 0.70
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crossref
Yusik Kim, Sangheon Lee, Ahmad Husein Alkaff, Dongsoo Yang
2026-03-07T07:23:07Z
置信度 0.70
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crossref
Chandrima Roy, Pramita Sen, Sushma Lavudya, Himabindu Vurimindi
2026-04-19T23:03:24Z
置信度 0.70
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Abstract Precise regulation of gene expression in batch bacterial cultures is challenging because the underlying dynamics vary with cellular physiological state over time. Although cell-silicon systems enable rapid, real-time optogenetic control, disturbance r…
crossref
Hari R. Namboothiri, Chelsea Y. Hu
2026-04-06T06:15:11Z
置信度 0.70
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crossref
2026-03-02T21:02:16Z
置信度 0.70
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Abstract Molecular recognition - which small molecule binds which protein, and with what selectivity - governs the efficacy, safety, and discovery of every therapeutic, yet binding specificity is still determined by experimental screening or by computational m…
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Sai T. Reddy
2026-06-09T04:30:15Z
置信度 0.70
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Karan Murjani, Vijai Singh
2026-02-07T04:06:10Z
置信度 0.70
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ABSTRACT In major diseases like cancer, many genes are dysregulated. While differential expression (DE) analyses help identify these genes, they do not reveal the transcriptional regulatory landscape between control and disease states. Here, we developed a pro…
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Zhang Shuo, Kumar Selvarajoo
2026-01-16T01:10:20Z
置信度 0.70
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crossref
2026-03-02T21:02:16Z
置信度 0.70
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Ajay Kumar, Monisa Anwer, Juveriya Israr
2026-02-07T04:06:10Z
置信度 0.70
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Summary Genome sizes vary across eukaryotes, largely because of differences in non-coding DNA. However, the physiological effects of this excess DNA are unclear. We engineered budding yeast strains carrying up to 12.8 Mb of predominantly non-coding human DNA, …
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Ning Lu, Xin Gao, Michael C. Lanz, Marianna E. Estrada 等
2026-06-28T10:30:24Z
置信度 0.70
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crossref
Bryan Hanley
2026-05-16T22:06:13Z
置信度 0.70