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• A protein-fragment complementation assay to quantify synthetic protein scaffold efficiency
  Abstract Scaffolds are powerful tools in synthetic biology used for various applications, from increasing yield to optimizing signalling specificity. Protein scaffolds can be built by fusing peptide binding domains (PBD) and attaching the peptide they bind to …
  crossref Pascale Lemieux, Alexandre K Dubé, Christian R Landry 2026-01-27T12:11:03Z 置信度 0.70
• Genome Editing Technologies and Synthetic Biology of Hyperthermophilic Archaea
  crossref Guanhua Yuan, Yang Zhang, Qunxin She 2026-02-24T05:20:17Z 置信度 0.70
• Text Mining Approaches for Protein Function Annotation: Challenges and Opportunities
  crossref Wang Hong, Zhang Chengxin 2025-12-23T01:54:48Z 置信度 0.70
• Next-generation sequencing (NGS) techniques in improvement of medicinal plants
  crossref Richa Gumasta, Abhijeet Garg 2026-05-29T12:09:26Z 置信度 0.70
• Existence and Localization of a Limit Cycle in a Class of Benchmark Biomolecular Oscillators
  Abstract Oscillatory behaviour is important in multiple biological contexts. However, the inherent nonlinearity and high dimensionality of mathematical models in biology makes proving the existence and the localization of limit cycle oscillations challenging. …
  crossref Sidhanta Mohanty, Shaunak Sen 2026-04-11T06:10:13Z 置信度 0.70
• Run or glide: muscles are indifferent while the tendon takes the strain
  Conventional diagonal stride skiing traditionally includes a glide phase, characterised by a period of relatively passive gliding on one ski. While the glide phase may take advantage of low ski-snow friction, it does not exhibit the same whole-cycle mechanical…
  crossref Øyvind Gløersen, Anders Lundervold, Amelie Werkhausen 2026-05-16T08:05:18Z 置信度 0.70
• EnzFinder: a sustainable alternative to chemical synthesis
  Abstract Enzymes have emerged as an important alternative to traditional catalysts in chemical industries over the past few decades owing to their sustainable nature. The application of enzymes in chemical synthesis relies on their ability to catalyse promiscu…
  crossref Akriti Jain, Nishtha Pandey, Arijit Roy 2026-02-13T04:10:15Z 置信度 0.70
• Introduction to RNA-Based Circuits and Devices
  RNA synthetic biology advances the engineering of RNA molecules for therapeutics and biotechnology. Synthetic systems, through RNA’s ability to modulate gene expression and its interaction with proteins, metabolites, and nucleic acids, offering precise and spa…
  crossref Dharmisha Solanki, Vijai Singh 2026-02-07T04:06:10Z 置信度 0.70
• Essential Oils as Biofriendly Alternatives to Synthetic Insect Repellents
  Most plant-based essential oil repellent products currently available on the market utilize a "green" approach based on the volatile properties of essential oils. In general, these essential oils contain terpenes, terpenoids, or phenylpropano…
  crossref Torben K. Heinbockel, Vonnie D. C. Shields 2026-04-22T01:18:38Z 置信度 0.70
• The Application and Performance Advantages of Synthetic Biology in Cosmetics Ingredient Production
  As an emerging interdisciplinary field, synthetic biology is having a profound impact on the cosmetics industry. This study aims to systematically explore the applications and effects of this approach in the production of cosmetic active ingredients. Genetic e…
  crossref Yuxin Lai 2026-02-11T01:15:11Z 置信度 0.70
• Harnessing synthetic biology for tetraterpenoid astaxanthin production: Recent advances and challenges
  crossref Yue Hou, Ailin Guan, Xuefen Fan, Jiufu Qin 2025-08-18T22:32:50Z 置信度 0.70
• An expedient, biology-laboratory-compatible method for preparing functional perfluoropolyether fluorosurfactants for droplet microfluidics
  Abstract Biocompatible fluorosurfactants are essential for many droplet microfluidic workflows but are often obtained from commercial sources because published syntheses of perfluoropolyether (PFPE)-based surfactants typically require acid chloride intermediat…
  crossref Chase Akins, Jessica L. Johnson, Gyorgy Babnigg 2026-03-30T03:20:14Z 置信度 0.70
• Synthetic Biology
  crossref Tiffany J. Vora 2026-05-01T00:34:43Z 置信度 0.70
• Engineering the gut microbiome: Synthetic biology approaches for human health and disease
  crossref Henry Sutanto, Deasy Fetarayani 2026-02-14T07:39:14Z 置信度 0.70
• Synthetic Strategies for Di-, Oligo-, and Polysialic Acids with Applications as Siglec Ligands
  crossref Hiroshi Tanaka, Chihiro Sato 2026-02-21T17:02:50Z 置信度 0.70
• Emerging Technologies Empowering the Biosynthesis of Paclitaxel
  crossref Liu Xiaonan, Zhang Yuanyuan, Li Jing, Jiang Huifeng 2026-05-20T09:01:13Z 置信度 0.70
• Fine-tuned synthetic transcription factors for production of 3′-phosphoadenosine-5′- phosphosulfate in yeast
  ABSTRACT Technologies developed over the past decade have made Saccharomyces cerevisiae a promising platform for producing various natural products. Balancing multi-enzyme expression, while maintaining robust microbial growth, remains a limiting factor for eng…
  crossref Madhushruti Borah, Shanna Gu, Essa M. Saied, Christoph Arenz 等 2026-02-03T02:55:17Z 置信度 0.70
• Mitochondrial Redox Signaling and Organelle-Targeted Strategies: Balancing Pro-Thrombotic Environmental Risks with Natural and Synthetic Antiplatelet Therapies
  crossref Andres Trostchansky 2026-05-13T17:57:16Z 置信度 0.70
• Computational design of orthogonal operators and synthetic repressors for transcriptional logic gates
  Orthogonal repressor-based logic gates have enabled the predictive design of genetic circuits using automated design algorithms. However, engineering complex genetic circuits has been limited by the availability of transcriptional logic gates that are orthogon…
  crossref Nathaniel Howitz, Stephen N. Rondthaler, Lauren B. Andrews 2026-08-04T05:36:18Z 置信度 0.70
• Towards autonomous biology: Compiler-Verified Protocols as a Foundation for Real-World AI Execution
  Abstract Artificial intelligence has advanced from analyzing experimental data to autonomously generating hypotheses, designing experiments, and coordinating closed loop discovery. Yet the translation from computational reasoning to physical execution remains …
  crossref Renjian Song, Yaokai Fu, Ziyan Zhao, Jigang Yu 等 2026-05-08T04:50:19Z 置信度 0.70
• Expression landscape of metabolic engineering enzymes in cyanobacteria
  Abstract Photosynthetic cyanobacteria are promising platforms for sustainable chemical production, as they can convert light and CO₂ into valuable compounds. Achieving this often requires engineering cyanobacteria with non-native enzymes with strong promoters …
  europepmc Hitesh Medipally, Anna Karlsson, Aman Dheer, Elton P. Hudson 等 2026 置信度 0.80
• Metabolic Engineering of <i>Escherichia coli</i> Nissle 1917 for Efficient Production of <i>p</i> -Coumaric Acid
  crossref Miaomiao Zhuang, Jie Song, Xiaoqing Hu, Xiaoyuan Wang 2026-01-01T07:48:41Z 置信度 0.70
• Sequence Generation and Phylogenetic Inference with Generative Flow Networks
  A bstract Phylogenetic inference remains computationally challenging due to the exponentially growing tree topology search space, and current methods rely heavily on multiple sequence alignments (MSAs) which are expensive and error-prone. We propose AncestorGF…
  crossref Qichen Huang, Carlos Michel Mourra-Diaz, Xiaozhen Wen, David Payette 2026-04-10T06:05:22Z 置信度 0.70
• RNA Structure Prediction and Folding Algorithms
  crossref Francisco J. Enguita, Ana Lúcia Leitão 2026-02-07T04:06:10Z 置信度 0.70
• Quantitative modeling reveals sources of variability in transcriptional activation assays
  Abstract Reporter cell assays, such as those used to detect estrogenic chemicals, can detect target chemicals at low concentrations and can be used to analyze chemical mixtures without a priori knowledge of the mixture components. However, the outputs of these…
  crossref Mark Greenwood, Kenneth F. Reardon, Ashok Prasad 2026-01-31T02:55:23Z 置信度 0.70
• CRISPR-Based RNA Editing and Regulation
  crossref Priyancka Arora, Vaishnavi Kumari, Ajay Kumar 2026-02-07T04:06:10Z 置信度 0.70
• Seven inducible promoters for <i>Zymomonas mobilis</i>
  Abstract Zymomonas mobilis is an ethanologenic Alphaproteobacterium with many interesting characteristics for fundamental research and applied microbial engineering. Although genetic engineering has been established for Z. mobilis since the 1980s, a rich set o…
  crossref Gerrich Behrendt 2026-03-19T10:10:15Z 置信度 0.70
• A Proteome-Calibrated Mechanistic Digital Twin of the Glioblastoma Astrocyte Derived from Patient Multi-Omic Data
  Abstract Digital twins of biological systems have been proposed as a framework for personalized medicine; however, existing implementations in oncology operate at the tissue or population scale with parameters derived from textbook kinetics rather than patient…
  crossref John D. Mayfield 2026-04-24T04:15:16Z 置信度 0.70
• TaxoFormer: Hierarchical Transformer for Predicting the Full Taxonomic Lineage of Protein Sequences
  Abstract Predicting labels in massive, hierarchically structured output spaces is a core challenge in machine learning. In this work, we use the problem of predicting the full taxonomic lineage of a protein from its sequence as a case study for this challenge.…
  crossref Mohammad Parsa, Kooshiar Azimian, Kathy Y. Wei 2026-06-09T14:00:14Z 置信度 0.70
• Methods for Molecular Recognition Computing
  The softmax attention mechanism in transformer architectures (Vaswani et al., 2017) is mathematically identical to the Boltzmann distribution governing molecular binding at thermal equilibrium (Boltzmann, 1877). Luce's Choice Axiom (1959) establishes this func…
  crossref Sai T Reddy 2026-04-04T02:30:18Z 置信度 0.70
• Plant intelligence in silico: Integrating hybrid artificial intelligence and synthetic biology to decode adaptive plant strategies
  crossref Mohsen Yoosefzadeh-Najafabadi, Dominique Michaud, Davoud Torkamaneh 2026-05-18T23:05:39Z 置信度 0.70
• Programmable RNA detection generates DNA barcodes for multiplexed phage-host interaction screening
  Here, we introduce Detectrons, modular biosensors that couples programmable toehold switches with retron-mediated reverse transcription to transduce RNA inputs into unique DNA barcodes. The ability to convert dynamic RNA signals into durable DNA records within…
  crossref Jihoon Han, Seth Shipman 2026-02-17T06:00:13Z 置信度 0.70
• Biofabrication of nanoparticles from medicinal plants: Challenges and future perspectives
  crossref Anubha Singh, Jyoti Upadhyay, Avisha Malik 2026-05-29T12:09:26Z 置信度 0.70
• Protein Engineering and Directed Evolution
  crossref Erin Elsa Abey, Anjana Eettikkal Mathew, Aysha Hiba Sheikhinte Veettil, Vishnu Kirthi Arivarasan 2026-05-17T22:36:35Z 置信度 0.70
• Regulating synthetic biology by naturalizing it: the mis-classification of a GE mosquito
  Abstract A recently developed genetically engineered (GE) mosquito with synthetic DNA has been categorized by the Secretariat of the Convention on Biological Diversity as a synthetic biology organism. In contrast, a key regulatory agency has construed it as a …
  crossref Zahra Meghani 2026-06-09T12:21:10Z 置信度 0.70
• Synthetic Biology Tools for Marine Actinobacteria
  crossref Muneer Oladipupo Yaqub, Ravali Arugonda, Aashika Jain, Lekshmi K. Edison 2026-08-02T22:28:50Z 置信度 0.70
• Frontier Technologies: AI, Synthetic Biology, and Omics Convergence
  crossref Surendra Sarsaiya, Archana Jain, Qihai Gong 2026-03-31T14:15:12Z 置信度 0.70
• Regulation of the Dynamics of Antibodies and Cell Membrane Molecules Through Synthetic Glycan Modification
  crossref Kazuya Kabayama, Yoshiyuki Manabe 2026-02-21T17:02:48Z 置信度 0.70
• Porous Framework Materials for C1 Biotransformation
  crossref Yu Jiangyue, Qiao Shan, Yang Yaning, Liu Xin 等 2025-12-29T07:09:13Z 置信度 0.70
• Synthetic biology and genetic engineering in pharmaceutical bioprospecting
  crossref Shashi Kant, Saheli Roy, Nandan Sarkar 2025-11-08T11:10:23Z 置信度 0.70
• Synthetic Combinatorial Minimisation of Cell Cycle Control in Yeast
  Abstract The eukaryotic cell cycle, with its inherent regulatory redundancy, provides an ideal target for exploring genome modularisation and minimisation through synthetic genomics. Building upon principles established by the Synthetic Yeast Genome (Sc2.0) pr…
  crossref Anastasiya Malyshava, Klaudia Ciurkot, Lucas Cañizares Alonso, Armand Grollemund 等 2026-07-27T20:20:19Z 置信度 0.70
• Application of Synthetic and Natural Biomedicine in Cancer Therapy
  crossref 2026-07-29T11:17:55Z 置信度 0.70
• Manipulating biosynthetic pathways for controlled secondary metabolite production
  crossref Nivedita Singh, Nandita Banerjee 2026-05-29T12:09:26Z 置信度 0.70
• Turning IUCN's Synthetic Biology Policy Into Action
  crossref Cock van Oosterhout 2026-01-11T11:03:35Z 置信度 0.70
• Synthetic Biology for Environmental Applications
  Synthetic biology, an interdisciplinary field combining biology, engineering, and computational science, serves as a tool for the advancement of environmental management by synthesizing new organisms with enhanced abilities to combat pollution, resource deplet…
  crossref S S Kirthiga, R Dhinesh 2026-03-11T07:36:49Z 置信度 0.70
• Synthetic biology-based approaches for enhancing microalgal performance
  crossref Xin Sun, Hongwei Li 2026-03-27T09:54:04Z 置信度 0.70
• Genome Reduction and Its Applications
  crossref Sathya Narayanan Venkatesan, Sujay Patil, Sangamithra Senthilkumar, Mugesh Sankaranarayanan 2026-05-17T22:30:40Z 置信度 0.70
• Anticipatory governance for responsible innovation in synthetic biology
  crossref 2026-05-17T00:24:47Z 置信度 0.70
• RNA-Based Vaccines
  crossref Hajra Ali Raja, Fatima Noor Malik, Hunaiza Fatima, Mustafeez Mujtaba Babar 2026-05-17T22:08:57Z 置信度 0.70
• Development of Synthetic Peptide-based Vaccines
  crossref Daniel Krois 2026-08-02T22:28:07Z 置信度 0.70
• CRISPR-Based RNA Detection
  crossref Fu Wang, Kulsoom, Wajahat Ali 2026-02-07T04:06:10Z 置信度 0.70
• Innovations in cell-free synthetic biology via microfluidic approaches
  crossref Samar Damiati 2025-09-06T11:16:06Z 置信度 0.70
• Expansion of Genetic Codes and Its Applications
  crossref Kowsalya Arjun Balakrishna, Karthik Loganathan, Sai Ramesh Anjaneyulu 2026-05-17T22:23:06Z 置信度 0.70
• Emerging Trends in Biopharmaceutical Manufacturing
  Biopharmaceutical manufacturing -- the production of therapeutic proteins, monoclonal antibodies, gene therapies, celltherapies, mRNA therapeutics, and oligonucleotide drugs under current Good Manufacturing Practice (cGMP) conditions-- is undergoing a technolo…
  datacite Marta Bianchi 2025 置信度 0.66 biopharmaceutical manufacturing; continuous bioprocessing; mRNA manufacturing; ATMP; BMTI; PAT; AI process control; Spain; biosimilar; cell therapy; cGMP; supply chain
• Emerging Trends in Biopharmaceutical Manufacturing
  Biopharmaceutical manufacturing -- the production of therapeutic proteins, monoclonal antibodies, gene therapies, celltherapies, mRNA therapeutics, and oligonucleotide drugs under current Good Manufacturing Practice (cGMP) conditions-- is undergoing a technolo…
  datacite Marta Bianchi 2025 置信度 0.66 biopharmaceutical manufacturing; continuous bioprocessing; mRNA manufacturing; ATMP; BMTI; PAT; AI process control; Spain; biosimilar; cell therapy; cGMP; supply chain
• Training School 1: The European Political context
  Training School 1 (TS1): The European Political Context was designed to strengthen the strategic understanding of the European research and innovation landscape among Research Managers and Administrators (RMAs) from IST and IST-ID. This two-day virtual event, …
  datacite Martins, Sofia, Candeias, Marta 2026 置信度 0.66
• Training School 1: The European Political context
  Training School 1 (TS1): The European Political Context was designed to strengthen the strategic understanding of the European research and innovation landscape among Research Managers and Administrators (RMAs) from IST and IST-ID. This two-day virtual event, …
  datacite Martins, Sofia, Candeias, Marta 2026 置信度 0.66
• A Flexible Digital Twin Framework for ATMP Production - Towards an efficient CAR T Cell Manufacturing
  This paper presents a flexible digital twin framework tailored for the biomanufacturing of advanced therapeutic medicinal products (ATMPs), particularly focusing on chimeric antigen receptor T cell (CAR T cell) therapy. CAR T cell therapies face significant ch…
  datacite Shoshi, Arber, Xia, Yuchen, Fieschi, Andrea, Ackermann, Thomas 等 2024 置信度 0.66 ATMPCAR T cell productionditgital twinflexible software frameworkskill modeling
• Sustainable to Biomanufacturing and Circular Bioeconomy Biotechnology for a Greener Future
  Sustainable Biomanufacturing and Circular Bioeconomy: Biotechnology for a GreenerFuture presents a comprehensive exploration of how biotechnology is reshaping modernmanufacturing through sustainable, resource-efficient, and environmentally responsibleapproache…
  datacite S.Dinesh Kumar, C. Ravinder Singh, T. Govindan, A.Kalidoss 2026 置信度 0.66
• Sustainable to Biomanufacturing and Circular Bioeconomy Biotechnology for a Greener Future
  Sustainable Biomanufacturing and Circular Bioeconomy: Biotechnology for a GreenerFuture presents a comprehensive exploration of how biotechnology is reshaping modernmanufacturing through sustainable, resource-efficient, and environmentally responsibleapproache…
  datacite S.Dinesh Kumar, C. Ravinder Singh, T. Govindan, A.Kalidoss 2026 置信度 0.66
• From Empirical Design To Autonomous Ecosystems: AI-Driven Advances, Challenges, And Future Directions In Precision Nanomedicine
  The integration of artificial intelligence (AI), machine learning (ML), and deep learning (DL) into nanomedicine and drug delivery is driving a fundamental paradigm shift from empirical, trial-and-error formulation discovery toward predictive, data-driven, and…
  datacite Hezam Saleh Mohammed Dhaif Allah* 2026 置信度 0.66 Artificial Intelligence; Machine Learning; Deep Learning; Nanomedicine; Targeted Drug Delivery; Lipid Nanoparticles (LNPs); Digital Twins; Autonomous Self-Driving Labs; Microphysiological Systems; Precision Medicine
• From Empirical Design To Autonomous Ecosystems: AI-Driven Advances, Challenges, And Future Directions In Precision Nanomedicine
  The integration of artificial intelligence (AI), machine learning (ML), and deep learning (DL) into nanomedicine and drug delivery is driving a fundamental paradigm shift from empirical, trial-and-error formulation discovery toward predictive, data-driven, and…
  datacite Hezam Saleh Mohammed Dhaif Allah* 2026 置信度 0.66 Artificial Intelligence; Machine Learning; Deep Learning; Nanomedicine; Targeted Drug Delivery; Lipid Nanoparticles (LNPs); Digital Twins; Autonomous Self-Driving Labs; Microphysiological Systems; Precision Medicine
• Biosynthesis of medium-chain length polyhydroxyalkanoates from pre-treated food wastewater
  Abstract Background The escalating global plastic waste crisis, coupled with the challenges of managing high-moisture food waste from industrial processing, has prompted nations worldwide to pursue sustainable alternatives and comprehensive waste-reduction str…
  datacite Aghasa Aghasa, Ranaprathap Katakojwala, Eunseok Lee, Sudharshan Juntupally 等 2026 置信度 0.66 BiochemistrySpace ScienceMedicineBiotechnologyEvolutionary Biology
• Biosynthesis of medium-chain length polyhydroxyalkanoates from pre-treated food wastewater
  Abstract Background The escalating global plastic waste crisis, coupled with the challenges of managing high-moisture food waste from industrial processing, has prompted nations worldwide to pursue sustainable alternatives and comprehensive waste-reduction str…
  datacite Aghasa Aghasa, Ranaprathap Katakojwala, Eunseok Lee, Sudharshan Juntupally 等 2026 置信度 0.66 BiochemistrySpace ScienceMedicineBiotechnologyEvolutionary Biology
• Strategic Host Organism Selection for Microbial Cell Factories: A Comprehensive Guide for Biomanufacturing and Drug Development
  Selecting the optimal microbial host is a foundational decision in the development of microbial cell factories (MCFs) for the sustainable biomanufacturing of chemicals and pharmaceuticals. This technical guide provides a systematic framework for host evaluatio…
  datacite metabolic engineering science 2026 置信度 0.66 Microbial cell factoriesHost organism selectionMetabolic engineeringSynthetic biologyGenome-scale metabolic models
• Strategic Host Organism Selection for Microbial Cell Factories: A Comprehensive Guide for Biomanufacturing and Drug Development
  Selecting the optimal microbial host is a foundational decision in the development of microbial cell factories (MCFs) for the sustainable biomanufacturing of chemicals and pharmaceuticals. This technical guide provides a systematic framework for host evaluatio…
  datacite metabolic engineering science 2026 置信度 0.66 Microbial cell factoriesHost organism selectionMetabolic engineeringSynthetic biologyGenome-scale metabolic models
• Code and Data for: Zero-Shot Foundation Models Predict Evolutionary Stability to Enable In Silico Optimization of Synthetic Promoters
  This repository contains the custom computational pipelines, datasets, and analysis scripts required to reproduce the findings presented in the manuscript "Zero-Shot Foundation Models Predict Evolutionary Stability to Enable In Silico Optimization of Synthetic…
  datacite Bhushan, Abhinav 2026 置信度 0.66
• Code and Data for: Zero-Shot Foundation Models Predict Evolutionary Stability to Enable In Silico Optimization of Synthetic Promoters
  This repository contains the custom computational pipelines, datasets, and analysis scripts required to reproduce the findings presented in the manuscript "Zero-Shot Foundation Models Predict Evolutionary Stability to Enable In Silico Optimization of Synthetic…
  datacite Bhushan, Abhinav 2026 置信度 0.66
• Engineering A Mimetic Environment For Articular Cartilage Production
  Human articular cartilage (AC), an anisotropic tissue lining the subchondral bone, functions to regularly resist deformational changes applied by daily activities such as walking, running, and more. Upon joint loading, a myriad of mechanical stresses and strai…
  datacite Robertson, Terreill Joseph 2027 置信度 0.66 BiomanufacturingBioreactorCartilageChondrogenesisStem Cell
• Integrating upstream and downstream planning to increase biomanufacturing profitability
  This repository contains the source code and numerical results for the paper "Integrating upstream and downstream planning to increase biomanufacturing profitability".
  datacite Anonymous 2026 置信度 0.66
• Integrating upstream and downstream planning to increase biomanufacturing profitability
  This repository contains the source code and numerical results for the paper "Integrating upstream and downstream planning to increase biomanufacturing profitability".
  datacite Anonymous 2026 置信度 0.66
• Data-Driven Control Strategies In Upstream Bioprocessing: Integrating Analytics, Automation, And Adaptive Systems
  Driven by process analytical technology (PAT), advanced sensor instrumentation, and multivariate statistical modeling, data-driven control strategies have opened up the next generation of biological manufacturing, enabling unprecedented levels of real-time pro…
  datacite Sai Surya Raja Amogha Tenneti 2026 置信度 0.66
• Data-Driven Control Strategies In Upstream Bioprocessing: Integrating Analytics, Automation, And Adaptive Systems
  Driven by process analytical technology (PAT), advanced sensor instrumentation, and multivariate statistical modeling, data-driven control strategies have opened up the next generation of biological manufacturing, enabling unprecedented levels of real-time pro…
  datacite Sai Surya Raja Amogha Tenneti 2026 置信度 0.66
• MirkoTUM/Integrated_Biomanufacturing_Public: Integrated_Biomanufacturing_Public_v1.2
  This repository contains the source code and numerical results for the paper "Integrating upstream and downstream planning to increase biomanufacturing profitability" handed in in August 2026.
  datacite MirkoTUM 2026 置信度 0.66
• Topologically Pure Defect Arrays: Curvature-Enforced +\frac{1}{2} Cores on Spherical Microcarriers as a Biomanufacturing Architecture
  Topological defects in active cell monolayers impose a distinct, charge-dependent mechanical state on the cells at their cores. We show that a single geometric choice—culturing on spherical microcarriers below a critical diameter—converts this into a manufactu…
  datacite Dennis Brown 2026 置信度 0.66 Biological physicsHuman biophysicsSoft condensed matterBiochemistry and cell biology not elsewhere classifiedMathematical physics not elsewhere classified
• Topologically Pure Defect Arrays: Curvature-Enforced +\frac{1}{2} Cores on Spherical Microcarriers as a Biomanufacturing Architecture
  Topological defects in active cell monolayers impose a distinct, charge-dependent mechanical state on the cells at their cores. We show that a single geometric choice—culturing on spherical microcarriers below a critical diameter—converts this into a manufactu…
  datacite Dennis Brown 2026 置信度 0.66 Biological physicsHuman biophysicsSoft condensed matterBiochemistry and cell biology not elsewhere classifiedMathematical physics not elsewhere classified
• Topologically Pure Defect Arrays: Curvature-Enforced +\frac{1}{2} Cores on Spherical Microcarriers as a Biomanufacturing Architecture
  Topological defects in active cell monolayers impose a distinct, charge-dependent mechanical state on the cells at their cores. We show that a single geometric choice—culturing on spherical microcarriers below a critical diameter—converts this into a manufactu…
  datacite Dennis Brown 2026 置信度 0.66 Biological physicsHuman biophysicsSoft condensed matterBiochemistry and cell biology not elsewhere classifiedMathematical physics not elsewhere classified
• Topologically Pure Defect Arrays: Curvature-Enforced +\frac{1}{2} Cores on Spherical Microcarriers as a Biomanufacturing Architecture
  Topological defects in active cell monolayers impose a distinct, charge-dependent mechanical state on the cells at their cores. We show that a single geometric choice—culturing on spherical microcarriers below a critical diameter—converts this into a manufactu…
  datacite Dennis Brown 2026 置信度 0.66 Biological physicsHuman biophysicsSoft condensed matterBiochemistry and cell biology not elsewhere classifiedMathematical physics not elsewhere classified
• Single-Step Extrusion Printing of Microgrooved Annulus Fibrosus Scaffolds via Patterned Nozzles.
  Intervertebral disk pathology, including disk herniation and degeneration, is a major contributor to chronic low back pain, and when conservative treatment fails, surgical management often involves discectomy-based procedures that leave residual annulus fibros…
  datacite Kluser, Nadine, Alig, Gion Ursin, Sprecher, Christoph, Woods, Xavier 等 2026 置信度 0.66 3D printingPCL scaffoldsangle-ply architectureannulus fibrosuscell alignment
• Exploring the Potential of Residual Aspergillus Mycelium as a Sustainable Material for Additive Biomanufacturing
  Non-degradable materials are responsible for a variety of negative socio-environmental effects. In order to realize a sustainable bioeconomy a circular design of production systems based on biogenic resources is inevitable. Consequently, the recycling of resid…
  datacite Silber, Nadine, Butzke, Sebastian, Protte-Freitag, Kristin, Renz, Jana 等 2024 置信度 0.66 3D printingadditive biomanufacturingcircular design of production, Liquid Deposition ModelingLDMmycelium
• A Conceptual Basis for Reducing the Number of Complex Multi- Parametric Experiments in Bio-Production Engineering via Artificial Intelligence
  The biologicalization of production technology requires a far-reaching transformation from fossil to biogenic raw materials as feedstock for various production processes. The development of sustainable paints, adhesives and plastics made predominantly from bio…
  datacite Schwarz, Oliver, Pröllochs, Robin, Löw, Frederik, Heinzelmann, Caroline 等 2024 置信度 0.66 Artificial IntelligenceBayesian OptimizationBio-ProductionBiointelligence, BiomanufacturingEnsemble Model
• On the Concept of Decentralization in Biointelligent Manufacturing
  Biointelligent manufacturing represents one of the most promising innovation paths towards a sustainable restructuring of industrial production. In doing so, it assumes significantly changing framework conditions for the production of a wide variety of goods. …
  datacite Miehe, Robert, :unav 2024 置信度 0.66 BiointelligenceBiomanufacturingDecentralization
• Plant-Based Oral Therapeutics: A Conceptual Framework for an Integrated Biotherapy Modality
  This manuscript presents a conceptual framework for plant-based oral therapeutics (PBOTs), defined as therapeutic molecules expressed within plant matrices and administered orally within those matrices to engage gut-mediated biological pathways. The framework …
  datacite Fowler, Gerissa, Duerr, Katharina, Brown, Gordon C., Shojai, Eraj 2026 置信度 0.66 plant-based oral therapeuticsplant molecular farmingoral biologicschronic kidney diseasecardiometabolic disease
• Disposabe bioreactors : the current state-of-the-art and recommended applications in biotechnology
  Erworben im Rahmen der Schweizer Nationallizenz (http://www.nationallizenzen.ch)
  datacite Eibl-Schindler, Regine, Kaiser, Stephan, Lombriser, Renate, Eibl, Dieter 2010 置信度 0.66 BiomanufacturingBioreactor typesCell culturesCFDDisposable bioreactor
• Engineered solar-driven recycling systems for sustainable fertilisation
  Harvesting food removes essential nutrients for plant growth, such as nitrogen and phosphorous, from the agricultural system. This is currently solved by applying chemical fertilisers, but their overuse contributes to environmental pollution with extensive soc…
  datacite Valton, Marine 2023 置信度 0.66
• Jupyter Notebook Code for “Data-Driven Insights to Accelerate Advanced Biomanufacturing”
  This page contains the datasets and code #O5097 Jupyter Notebook Code for “Data-Driven Insights to Accelerate Advanced Biomanufacturing”. Data literature-derived cultivation experiments for polyhydroxybutyrate (PHB) production in Synechocystis sp. PCC 6803 and…
  datacite Lalonde, Jessica N. 2026 置信度 0.66
• WuXiUI vs WuXiUP: What Patent WO2020088180A1 Actually Covers — A Correction Teardown (Sail Research SR-2026-0008-F)
  Full Report SR-2026-0008-F. An evidence-gated teardown showing that patent WO2020088180A1 (continuous-harvest no-bleed perfusion) maps architecturally to WuXi Biologics' WuXiUP platform, not WuXiUI (ultra-intensified intermittent-perfusion fed-batch) — correct…
  datacite Sail Research 2026 置信度 0.66 CDMObiomanufacturingperfusionintensified fed-batchWuXi Biologics
• WuXiUI vs WuXiUP: What Patent WO2020088180A1 Actually Covers — A Correction Teardown (Sail Research SR-2026-0008-F)
  Full Report SR-2026-0008-F. An evidence-gated teardown showing that patent WO2020088180A1 (continuous-harvest no-bleed perfusion) maps architecturally to WuXi Biologics' WuXiUP platform, not WuXiUI (ultra-intensified intermittent-perfusion fed-batch) — correct…
  datacite Sail Research 2026 置信度 0.66 CDMObiomanufacturingperfusionintensified fed-batchWuXi Biologics
• V. natriegens genome-scale metabolic model development and its application for the production of polyhydroxybutyrate
  The widespread adoption of microbes for the bioproduction of commodity chemicals as a sustainable alternative to petrochemical synthesis is hindered by low productivities. Vibrio natriegens, the fastest growing organism known, is gaining interest to address th…
  datacite Coppens, Lucas 2024 置信度 0.66
• Serum-free media development and validation for cultivation of C2C12 immortalised murine myosatellite cell line for cultivated meat
  Abstract: The development of cost-effective, serum-free media is critical for scalable cultivated meat production. This study used Design of Experiments (DoE) and high-throughput screening to develop "MMM1", an animal-free, serum-free medium for the C2C12 muri…
  datacite Gordon-Petrovskii, William 2026 置信度 0.66 Cell BiologyCultivated Meat
• Multi omics reveals mesodermal fate bias and enables predictive cell state control in human pluripotent stem cell biomanufacturing
  Abstract Despite accelerating interest in using human induced pluripotent stem cell (hiPSC)–derived products for disease modeling and therapeutic development, there is substantial evidence that conventional culture approaches do not fully recapitulate natural …
  preprints James Colter, Tiffany Dang, Emilie Gysel, Daniel Young 等 2026 置信度 0.74
• Space Crop Menus for Astronaut Nutrition That Surpass Martian Biomanufacturing Bioplastic Needs After Waste Digestion
  Martian missions call for renewable supply chains of the 3D-printable bioplastic polyhydroxybutyrate (PHB). Because food waste can be anaerobically digested into methane and then bacterially converted into PHB, we analyzed the possible coupling between food wa…
  preprints Jithran N. Wainwright Ekanayake, Soumyajit Sen Gupta, Harsh Soni, Christian P. Nielsen 等 2026 置信度 0.74
• Development and demonstration of a Modular Astrobiological Experiments (MAEx) payload for autonomous biological monitoring in Low Earth Orbit (LEO)
  preprints 2026 置信度 0.74
• A Toolbox for Biomanufacturing of Functionalised PHA Nanoparticles with <i>C. necator</i>
  Abstract Microbes have the potential to manufacture plastics from sustainable feedstocks while enabling novel material properties and functions that are not easily accessible through conventional chemical synthesis. Realising this potential requires a comprehe…
  preprints John Allan, Lisa J. K. Zillig, Simona Della Valle, Harrison Steel 2026 置信度 0.74
• Cultivation-dependent effects of quorum sensing signals on a lactic acid and chain-elongating bacterium
  preprints 2026 置信度 0.74
• HaloMPNN: retraining ProteinMPNN on halophilic proteomes for salt-tolerant enzyme design
  preprints 2026 置信度 0.74
• Modular Assembly of the Astaxanthin Biosynthetic Pathway via SNARE-Derived Coiled-Coil Domains
  preprints 2026 置信度 0.74
• The Role of the Biomanufacturing Industry in Developing Diagnostics and mRNA Vaccines Against COVID-19
  COVID-19, caused by the new type of coronavirus SARS-CoV-2, has put an unprecedented impact on health, economy and social areas around the globe. It created an urgent global need for rapid diagnostics, effective therapeutics, and scalable vaccine manufacturing…
  europepmc Ishfaq Ahmed, Quendrix Martinez, Shayne McRae, Ashwin Dharmalingam 2026 置信度 0.80
• Cultivation-dependent effects of quorum sensing signals on a lactic acid and chain-elongating bacterium
  preprints 2026 置信度 0.74
• From Discovery Proteomics to Process-Informed Monitoring in Biomanufacturing Chassis Development
  Abstract Gaining control of existing biomanufacturing chassis organisms, such as Escherichia coli K12 , and novel isolates, such as the salt tolerant Halomonas bluephagenesis sp TD01 studied here may be facilitated by the investigation and monitoring of their …
  europepmc Matthew R. Russell, Philip J. Brownridge, Joseph Windo, Nigel S. Scrutton 等 2025 置信度 0.80