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• Biological databases in the age of generative artificial intelligence
  Summary: Modern biological research critically depends on public databases. The introduction and propagation of errors within and across databases can lead to wasted resources as scientists are led astray by bad data or have to conduct expensive validation exp…
  openalex Mihai Pop, Teresa K. Attwood, Judith A. Blake, Philip E. Bourne 等 2024-12-26 置信度 0.84 Stewardship (theology)Computer scienceData scienceGenerative grammarBiological data
• Anti-tuberculosis treatment strategies and drug development: challenges and priorities
  Despite two decades of intensified research to understand and cure tuberculosis disease, biological uncertainties remain and hamper progress. However, owing to collaborative initiatives including academia, the pharmaceutical industry and non-for-profit organiz…
  openalex Véronique Dartois, Eric J. Rubin 2022-04-27 置信度 0.82 BiologyTuberculosisDrug developmentDrugComputational biology
• Diagnostic strategies for unknown primary cancer
  Unknown primary cancer (UPC) is defined by the presence of metastatic disease for which a primary site is undetectable on presentation. Computed tomography scan of the body was performed routinely in search of the primary cancer and invasive procedures were pu…
  openalex Gauri R. Varadhachary, James L. Abbruzzese, Renato Lenzi 2004-03-22 置信度 0.74 MedicineBreast cancerRadiologyPositron emission tomographyMagnetic resonance imaging
• Plastic Fruit Stickers in Industrial Composting─Surface and Structural Alterations Revealed by Electron Microscopy and Computed Tomography
  Often large quantities of plastics are found in compost, with price look-up stickers being a major but little-explored component in the contamination path. Stickers glued to fruit or vegetable peels usually remain attached to the organic material despite sorti…
  openalex Max Groß, Matthias Mail, Olivia Wrigley, Rafaela Debastiani 等 2024-04-10 置信度 0.84 CompostDegradation (telecommunications)Scanning electron microscopeFourier transform infrared spectroscopyChemistry
• Cell-type-specific synaptic motifs generate coupled mean-variability dynamics in recurrent neural networks
  Synaptic-resolution network connectomics has revealed that brain circuits feature fine-scale structural connectivity, such as pairs of correlated synaptic couplings known as second-order motifs. Large-scale recordings of neuronal activity in networks containin…
  datacite Zhang, Meiyi, Yu, Jinjian, Tao, Louis, Shao, Yuxiu 2026 置信度 0.79 Neurons and Cognition (q-bio.NC)Disordered Systems and Neural Networks (cond-mat.dis-nn)Neural and Evolutionary Computing (cs.NE)FOS: Biological sciencesFOS: Physical sciences
• Postmodern Physics of Hamzah Information.(285)
  تحلیل فوق‌دکتری جامع، فوق‌تخصصی، بدون کوچک‌ترین ساده‌سازی و کاملاً ضدگلوله برای نظریه و معمای شماره ۴۱ از ۱۰۰ (از کلان‌مجموعه مهندسی و دستکاری ساختار واقعیت با نام تجاری HamzahXcell): «کدگ��اری میدان‌های انسجام بوزونی بوز-اینشتین برای ساخت لیزرهای مادی صلب گرا…
  datacite HAMZAH, SEYED RASOUL 2026 置信度 0.68
• Postmodern Physics of Hamzah Information.(285)
  تحلیل فوق‌دکتری جامع، فوق‌تخصصی، بدون کوچک‌ترین ساده‌سازی و کاملاً ضدگلوله برای نظریه و معمای شماره ۴۱ از ۱۰۰ (از کلان‌مجموعه مهندسی و دستکاری ساختار واقعیت با نام تجاری HamzahXcell): «کدگذاری میدان‌های انسجام بوزونی بوز-اینشتین برای ساخت لیزرهای مادی صلب گران…
  datacite HAMZAH, SEYED RASOUL 2026 置信度 0.68
• Non-Von Neumann Architectures for Neuromorphic Computing
  This paper proposes a novel computing architecture that diverges from the traditional Von Neumann model by integrating computation and storage within a neuromorphic network. The core concept involves utilizing a neural network constructed from novel storage me…
  datacite Zhang, Jincheng 2026 置信度 0.77 neuromorphic engineeringcomputer sciencecs.nephotonicsscalability
• Non-Von Neumann Architectures for Neuromorphic Computing
  This paper proposes a novel computing architecture that diverges from the traditional Von Neumann model by integrating computation and storage within a neuromorphic network. The core concept involves utilizing a neural network constructed from novel storage me…
  datacite Zhang, Jincheng 2026 置信度 0.77 neuromorphic engineeringcomputer sciencecs.nephotonicsscalability
• 🌀 LRO-κ⁸ SPINE + 3.1.3 MASTER FILE including cross platform LRO-κ⁸ SPINE + 3.1: A Geometric Control Language for Quantum-Holographic Field Manipulation – Extended AI Migration Protocol with Holographic GPU, Quantum Circuit Execution, Volumetric Field-Effect Display, Automatic C/Rust Kernel Generation, and Official Verification Suite. Including LRO-κ⁸ QUANTUM PLATFORM PATCH — CHINA EDUCATIONAL DEPLOYMENT
  🌀 LRO-κ⁸ SPINE + 3.1.3 MASTER FILE including cross platform LRO-κ⁸ SPINE + 3.1.3 : A Geometric Control Language for Quantum-Holographic Field Manipulation – Extended AI Migration Protocol with Holographic GPU, Quantum Circuit Execution, Volumetric Field-Effec…
  datacite Blakeley, Christopher 2026 置信度 0.72
• 🌀 LRO-κ⁸ SPINE + 3.1.3 MASTER FILE including cross platform LRO-κ⁸ SPINE + 3.1: A Geometric Control Language for Quantum-Holographic Field Manipulation – Extended AI Migration Protocol with Holographic GPU, Quantum Circuit Execution, Volumetric Field-Effect Display, Automatic C/Rust Kernel Generation, and Official Verification Suite. Including LRO-κ⁸ QUANTUM PLATFORM PATCH — CHINA EDUCATIONAL DEPLOYMENT
  🌀 LRO-κ⁸ SPINE + 3.1.3 MASTER FILE including cross platform LRO-κ⁸ SPINE + 3.1.3 : A Geometric Control Language for Quantum-Holographic Field Manipulation – Extended AI Migration Protocol with Holographic GPU, Quantum Circuit Execution, Volumetric Field-Effec…
  datacite Blakeley, Christopher 2026 置信度 0.72
• Postmodern Physics of Hamzah Information.(284)
  تحلیل فوق‌دکتری جامع، فوق‌تخصصی، بدون کوچک‌ترین ساده‌سازی و کاملاً ضدگلوله برای نظریه و معمای شماره ۳۱ از ۱۰۰ (از کلان‌مجموعه مهندسی و دستکاری ساختار واقعیت با نام تجاری HamzahXcell): «ماتریس فرکتالی میدان‌های پیمانه‌ای برای هک پروتکل‌های برهم‌کنش قوی هسته‌ای»…
  datacite HAMZAH, SEYED RASOUL 2026 置信度 0.72
• Postmodern Physics of Hamzah Information.(284)
  تحلیل فوق‌دکتری جامع، فوق‌تخصصی، بدون کوچک‌ترین ساده‌سازی و کاملاً ضدگلوله برای نظریه و معمای شماره ۳۱ از ۱۰۰ (از کلان‌مجموعه مهندسی و دستکاری ساختار واقعیت با نام تجاری HamzahXcell): «ماتریس فرکتالی میدان‌های پیمانه‌ای برای هک پروتکل‌های برهم‌کنش قوی هسته‌ای»…
  datacite HAMZAH, SEYED RASOUL 2026 置信度 0.72
• Postmodern Physics of Hamzah Information.(282)
  تحلیل فوق‌دکتری جامع، فوق‌تخصصی، بدون کوچک‌ترین ساده‌سازی و کاملاً ضدگلوله برای نظریه و معمای شماره ۱۱ از ۱۰۰ (از کلان‌مجموعه مهندسی و دستکاری ساختار واقعیت با نام تجاری HamzahXcell): «کنترل و برنامه‌نویسی نوسانات کوانتومی خلاء برای خلق ماده پایدار از هیچ» ($\…
  datacite HAMZAH, SEYED RASOUL 2026 置信度 0.72
• Postmodern Physics of Hamzah Information.(282)
  تحلیل فوق‌دکتری جامع، فوق‌تخصصی، بدون کوچک‌ترین ساده‌سازی و کاملاً ضدگلوله برای نظریه و معمای شماره ۱۱ از ۱۰۰ (از کلان‌مجموعه مهندسی و دستکاری ساختار واقعیت با نام تجاری HamzahXcell): «کنترل و برنامه‌نویسی نوسانات کوانتومی خلاء برای خلق ماده پایدار از هیچ» ($\…
  datacite HAMZAH, SEYED RASOUL 2026 置信度 0.72
• Postmodern Physics of Hamzah Information.(281)
  تحلیل فوق‌تخصصی، فرمول‌بندی هندسی-ریاضیاتی و اثبات سطح فوق‌دکتری جامع، بدون کوچک‌ترین ساده‌سازی و کاملاً ضدگلوله برای نظریه و معمای شماره ۱ از ۱۰۰ (از کلان‌مجموعه دستکاری و مهندسی فضا-زمان با نام تجاری HamzahXcell): «مهندسی هولوگرافیک ساختار محاسباتی فضا-زمان»…
  datacite HAMZAH, SEYED RASOUL 2026 置信度 0.72
• Postmodern Physics of Hamzah Information.(281)
  تحلیل فوق‌تخصصی، فرمول‌بندی هندسی-ریاضیاتی و اثبات سطح فوق‌دکتری جامع، بدون کوچک‌ترین ساده‌سازی و کاملاً ضدگلوله برای نظریه و معمای شماره ۱ از ۱۰۰ (از کلان‌مجموعه دستکاری و مهندسی فضا-زمان با نام تجاری HamzahXcell): «مهندسی هولوگرافیک ساختار محاسباتی فضا-زمان»…
  datacite HAMZAH, SEYED RASOUL 2026 置信度 0.72
• Thousands of Entangled Cellular Metabolic Networks Solved by Quantum Computers... First Demonstration of the QSVT Algorithm
  • Published on bioRxiv, presenting the first quantum algorithm to dramatically accelerate Flux Balance Analysis (FBA), a core technique in cellular metabolism research. • Overcomes the computational limits of existing classical computing by introducing the Qua…
  datacite inquantio 2026 置信度 0.76 quantum biology
• Mars Colony Unified Lifecycle Design Specification, Version 3.3
  This specification develops a unified lifecycle design for a permanent Mars colony scaling from initial outpost (~2046) through terraforming-class capability (~2100+). The design centers on pit-crater architecture using natural basalt walls as primary structur…
  datacite Lusk, A. C. 2026 置信度 0.79 marsspace settlementplanetary engineeringISRUlifecycle design
• Mars Colony Unified Lifecycle Design Specification, Version 3.3
  This specification develops a unified lifecycle design for a permanent Mars colony scaling from initial outpost (~2046) through terraforming-class capability (~2100+). The design centers on pit-crater architecture using natural basalt walls as primary structur…
  datacite Lusk, A. C. 2026 置信度 0.79 marsspace settlementplanetary engineeringISRUlifecycle design
• Axiomatic V3 Core Fusion: Formally Proven Deterministic Foundations under Ada/SPARK for DO-178C DAL A Critical Systems
  ABSTRACT: This paper introduces the formal implementation and verification of the V3 Architecture (Blida Standard) encapsulated within the Ada/SPARK axiomatic type system, achieving a paradigm shift from traditional stochastic and empirical computing to absolu…
  datacite benhadid, outail 2026 置信度 0.76 Ada/SPARK, Blida Standard, V3 Architecture, Formal Verification, Saturating Arithmetic, Heptadic Closure, DO-178C DAL A, O(1) Complexity, Deterministic Systems, Axiomatic Type System, Modulo-9, Digital Root, GNATprove, Runtime Exception Absence, AoRTE, Static Analysis, Phase Coherence, Numerical Stability
• Axiomatic V3 Core Fusion: Formally Proven Deterministic Foundations under Ada/SPARK for DO-178C DAL A Critical Systems
  ABSTRACT: This paper introduces the formal implementation and verification of the V3 Architecture (Blida Standard) encapsulated within the Ada/SPARK axiomatic type system, achieving a paradigm shift from traditional stochastic and empirical computing to absolu…
  datacite benhadid, outail 2026 置信度 0.76 Ada/SPARK, Blida Standard, V3 Architecture, Formal Verification, Saturating Arithmetic, Heptadic Closure, DO-178C DAL A, O(1) Complexity, Deterministic Systems, Axiomatic Type System, Modulo-9, Digital Root, GNATprove, Runtime Exception Absence, AoRTE, Static Analysis, Phase Coherence, Numerical Stability
• Postmodern Physics of Hamzah Information.(288)
  تحلیل فوق‌دکتری جامع، فوق‌تخصصی، بدون کوچک‌ترین ساده‌سازی و کاملاً ضدگلوله برای نظریه و معمای شماره ۷۱ از ۱۰۰ (فاز پیشرفته مهندسی ارگانیک و بیوفیزیک فرین در پروتکل جامع فیزیک اطلاعات حمزه) با نام تجاری HamzahXcell: «ماتریس توپولوژیک میدان‌های چرخش فرومونیک-کوا…
  datacite HAMZAH, SEYED RASOUL 2026 置信度 0.72
• Postmodern Physics of Hamzah Information.(287)
  تحلیل فوق‌دکتری جامع، فوق‌تخصصی، بدون کوچک‌ترین ساده‌سازی و کاملاً ضدگلوله برای نظریه و معمای شماره ۶۱ از ۱۰۰ (فاز پیشرفته کلان‌نظریه‌ها و مهندسی پروتکل‌های خلاء با نام تجاری HamzahXcell): «کدگذاری فرکانس‌های میدان شبه‌ذره‌ای اکسیوتون برای هک پروتکل‌های بازتاب…
  datacite HAMZAH, SEYED RASOUL 2026 置信度 0.68
• Hamzah Information Physics: Gravity is not a Function of Mass but a Function of Information Processing, Meaning Information is the Ruler of Matter and Energy. The proof is the bending of light near a 1-petabyte pen drive in operation, which is greater than near a massive dead rocky planet. That is, "intelligence" and "information" are heavier than "stone and soil. via 1155-Dimensional Tensor Mechanics, Hamzah Equation.
  اَبَر-لاگرانژین ۱۱۵۵ حمزه در بستر فیزیک اطلاعات و اثبات وضعیت آن ۴ فلش‌مموری، باید این معادله را به عنوان یک «میدان اطلاعاتی جامع» تحلیل کنیم. در این مدل، فلش‌مموری دیگر یک شیء فیزیکی نیست، بلکه یک تکینگی اطلاعاتی (Information Singularity) در فضای ۱۱۵۵-بعدی اس…
  datacite HAMZAH, SEYED RASOUL 2026 置信度 0.68
• Hamzah Information Physics: Gravity is not a Function of Mass but a Function of Information Processing, Meaning Information is the Ruler of Matter and Energy. The proof is the bending of light near a 1-petabyte pen drive in operation, which is greater than near a massive dead rocky planet. That is, "intelligence" and "information" are heavier than "stone and soil. via 1155-Dimensional Tensor Mechanics, Hamzah Equation.
  اَبَر-لاگرانژین ۱۱۵۵ حمزه در بستر فیزیک اطلاعات و اثبات وضعیت آن ۴ فلش‌مموری، باید این معادله را به عنوان یک «میدان اطلاعاتی جامع» تحلیل کنیم. در این مدل، فلش‌مموری دیگر یک شیء فیزیکی نیست، بلکه یک تکینگی اطلاعاتی (Information Singularity) در فضای ۱۱۵۵-بعدی اس…
  datacite HAMZAH, SEYED RASOUL 2026 置信度 0.68
• Graph-based pangenomics reveals the genetic basis of agronomic traits in tomato fruits.
  Tomato serves as a globally important vegetable crop and a genetic model organism, and the improvement of its agronomic traits represents a central objective in breeding. While graph-based pangenomes comprehensively capture species-wide genetic diversity, thos…
  pubmed Su X, Du R, Xing Z, Yang Q 等 2026 Sep 置信度 0.96 biologycomputational biologymedicinegeneticsbiotechnology
• Surgfm-Slam: robust surgical scene reconstruction via 3D foundation adaptation model.
  Surgical scene reconstruction is a critical prerequisite for intraoperative navigation in robotic surgery. Although deep neural networks (DNNs) have advanced surgical scene reconstruction, their performance degrades severely when confronted with texture-sparse…
  pubmed Xiaoxi L, Gan L, Bingwen D, Guangcheng C 等 2026 Dec 置信度 0.96 cs.lgartificial intelligencecomputer and information sciencescs.cvcs.ai
• Integrated machine learning and transcriptomics reveal immune infiltration-related orthologous transcription genes in cerebral ischemic injury.
  Ischemic brain injury is a major contributor to global mortality and disability. Despite extensive pathological characterization, systematic integration of rodent transcriptomic data remains limited. This study investigates orthologous transcription factors (T…
  pubmed Xu H, Huang X, Hong MY, Xu J 等 2026 置信度 0.93 interpretabilitymathematics educationprocess managementintensive care medicinemarine engineering
• Pro-inflammatory diet in pregnancy associated with increased risk of abnormal perinatal outcomes: evidence from dietary inflammatory index in the UK biobank.
  This study aimed to investigate the association between a pro-inflammatory diet in pregnancy, assessed via the Dietary Inflammatory Index (DII), and abnormal perinatal outcomes (APOs), including miscarriage and stillbirth. Leveraging the UK Biobank cohort, we …
  pubmed Sheng L, He W, Wang F, Weng X 等 2026 置信度 0.91 medicinepsychologyinternal medicinecancerbiological sciences
• Identification of PD-1-Related Genes as Prognostic Biomarkers in Lung Adenocarcinoma.
  The PD-1/PD-L1 axis plays a critical role in suppressing T-cell activation and facilitating immune evasion in lung adenocarcinoma (LUAD). This study focused on PD-1-related genes to develop a robust prognostic prediction model for LUAD.
  pubmed Jia B, Gong T, Chen C, Sun B 等 2026 置信度 0.89 biochemistrygeneticsmicrobiologyq-bio.gnbiological sciences
• IsoformSwitchAnalyzeR v2: analysis of functional isoform changes in long-read and single-cell sequencing data.
  Alternative splicing enables a single gene to produce a variety of mRNA transcripts, significantly enhancing protein diversity in higher eukaryotes. Isoform switching refers to the differential usage of a gene's transcripts and occurs pervasively across physio…
  pubmed Han C, Gilis J, Delgado EI, Clement L 等 2026 Sep 置信度 0.96 biologymedicinegeneticscomputational biologyneuroscience
• Correction: Transcriptome-informed metabolic modeling reveals astrocyte-specific vulnerabilities in mild cognitive impairment and Alzheimer's disease progression.
  [This corrects the article DOI: 10.3389/fbinf.2026.1816121.].
  pubmed Angarita-Rodríguez A, Vargas-López V, Pinzón A, Sandoval-Hernandez A 等 2026 置信度 0.75
• An automated deep learning-based pipeline for 3D characterisation of the murine upper airway from micro-CT.
  Upper airway structure and function are affected in several respiratory (e.g., obstructive sleep apnoea, allergic rhinitis, and asthma) and congenital [e.g., Down syndrome (DS)] conditions. Although murine models are widely used to study airway pathology and t…
  pubmed Belmans F, Llambrich S, Vos W, Maes F 等 2026 置信度 0.86 physical medicine and rehabilitationrehabilitationmedicinetaxonomyintensive care medicine
• Exploring the cardioprotective role of metformin against isoproterenol-induced myocardial infarction using computational, cellular, and animal models.
  Despite significant advances in therapeutic techniques, Myocardial infarction (MI) is an important root cause of morbidity and death worldwide. Metformin (MET), a primary antidiabetic medication, has been studied for its possible cardioprotective properties. T…
  pubmed Saini D, Maharana KC, Jha KP, Singh S 2026 Sep 置信度 0.96 medicinepharmacologybiotechnologybiological sciences not elsewhere classifiedscience policy
• ProGenFixer: An Ultrafast and Accurate Tool for Correcting Prokaryotic Genome Sequences Using a Mapping-Free Algorithm.
  Although several tools exist for prokaryotic genome correction, most depend on external read mappers that impose computational overhead and usability barriers, leaving a need for fast, accurate, standalone solutions. We present ProGenFixer, a mapping-free tool…
  pubmed Song L, Wang M, Liao X, Wu J 等 2026 置信度 0.96 biologycomputational biologyartificial intelligencecomputer and information sciencescomputer science
• Selaginella bryopteris-derived silver nanoparticles against ovarian cancer cells: green synthesis, in vitro anticancer activity, and exploratory in silico analysis.
  Chronic hormonal imbalances and associated symptoms characterize ovarian cancer. PARP-1 inhibitors, such as olaparib and ruparib, are used to treat it, but new drugs are needed to overcome toxicity and resistance issues. PARP inhibition in BRCA1/2 -mutated can…
  pubmed Dey S, Wadhwa K, Kumari N, Pandey C 等 2026 置信度 0.89 cancerpharmacologyinternal medicinebiotechnologymedical physics
• AHCSIS: adaptive evaluation model for stereoscopic visual comfort based on HHT-CSP-SSA and improved SNN.
  To address the issues of feature redundancy in the feature extraction process, as well as the fact that the simulation of biological neural activity remains limited in the SNN encoding layer and the lack of temporal information in the SNN encoding layer, the s…
  pubmed Wang Y, Bai J, Zhang H, Wu Y 2026 置信度 0.93 cs.neeess.ivconvolutional neural networkartificial neural networkcomputer vision and pattern recognition
• Potential c-Met-targeted pyrazole-pyridine-oxadiazole hybrids: synthesis, anticancer activity, and computational rationale.
  A novel series of pyrazole-pyridine-1,3,4-oxadiazole hybrid derivatives (10a-m) was designed, synthesized, and characterized by IR, 1 H NMR, 13 C NMR, mass spectrometry, and elemental analysis. The multi-step route proceeded via nucleophilic aromatic substitut…
  pubmed Dave PA, Maheta JB, Lakhnotra DK, Shaikh NH 等 2026 Aug 26 置信度 0.96 medicinepharmacologybiological sciencesbiochemistrychemistry
• Dopant Engineering of Isostructural Metal Nanoclusters for Modulating CO(2) Electroreduction.
  Achieving atomic-level insight into how dopants regulate the electrocatalytic CO 2 reduction reaction (eCO 2 RR) of metal nanoparticles is challenging due to the lack of well-defined, compositionally tunable, and structurally identical model systems. Herein, w…
  pubmed Deng G, Kim J, Yan Q, Park S 等 2026 Aug 26 置信度 0.96 materials sciencecatalysischemistrychemical engineeringquantum dot
• ReMeDy: A Flexible Statistical Framework for Region-Based Detection of DNA Methylation Dysregulation.
  Region-based epigenome-wide association studies have demonstrated improved statistical power and biological interpretability compared with probe-wise analyses of DNA methylation data. However, most existing region-based methods characterize methylation dysregu…
  pubmed Chatterjee S, Meshram S, Arunkumar G, Tekola-Ayele F 等 2026 Sep 置信度 0.96 computer and information sciencescs.lgcs.aibiologymedicine
• Phytochemical Profiling and Neuropharmacological Evaluation of Baccaurea motleyana Bark Extract: In Vivo and In Silico Approaches.
  Depression, anxiety, insomnia, and muscle spasms are globally prevalent disorders. Although Baccaurea motleyana is traditionally used in folk medicine, its neuroprotective efficacy remains unexplored. This study evaluates the anxiolytic, antidepressant, sedati…
  pubmed Ahsan MT, Ekram MEH, Al Mahmud K, Hasan T 等 2026 置信度 0.96 medicinepharmacologybiological sciences not elsewhere classifiedbiochemistrybiological sciences
• Mechanically Interlocked Molecules: A Supramolecular Computational Picture of Rotaxane-Based Switches, Shuttles, and Tristable Devices in Solution.
  This contribution highlights a coherent series of recent computational studies devoted to the theoretical characterization of mechanically interlocked molecules (MIMs)-specifically [2]rotaxane molecular shuttles and switches-in organic solvents. Combining dens…
  pubmed Zazza C 2026 Sep 置信度 0.96 materials sciencecond-mat.mtrl-sciphysicsphysics.comp-phchemistry
• Photovoltaic Stimulation of Mouse and Pig Retina With Pyrolytic Carbon Microelectrodes Integrated on High-Density Silicon Solar Cell Arrays.
  In this work, we introduce carbon as a novel electrode material in retinal prosthesis. We fabricate Si-based photovoltaic retinal implants with single p-n junctions in 40 µm and 200 µm pixels and successfully integrate pyrolytic carbon elec…
  pubmed Matsumoto A, Kusumanchi P, Madsen JG, Jørgensen AC 等 2026 Aug 25 置信度 0.96 materials sciencecond-mat.mtrl-scicatalysisquantum dotchemistry
• Conformational ensembles of flexible multidomain proteins: How close are we to accurate and reliable predictions?
  Multidomain proteins connected by flexible linkers populate conformational ensembles that are challenging to characterize using conventional structural biology methods. In domain-linker-domain (DLD) proteins, linker-mediated inter-domain relative positions and…
  pubmed Rodriguez S, Fournet A, Bartels S, Pajkos M 等 2026 Aug 26 置信度 0.96 physical sciencescomputer sciencebiologystat.apphysics.bio-ph
• ACC1 inhibition enhances BCG-induced trained immunity by reprogramming Acetyl-CoA metabolism.
  Trained immunity enhances long-term innate immune responsiveness through metabolic and epigenetic rewiring. Using BCG as a model, we demonstrate that inhibition of acetyl-CoA carboxylase 1 (ACC1) enhances BCG-induced trained immunity by increasing intracellula…
  pubmed Baydemir I, Nikolka F, Bulut Ö, Ferreira AV 等 2026 Aug 25 置信度 0.96 medicinebiologyinternal medicinecell biologysynthetic biology
• The Influenza-Specific Immunoglobulin Repertoire - Nimble Yet Steeped in Tradition.
  Influenza virus has circulated in the human population and co-evolved with us for centuries or longer, shaping our immune repertoires through a continuous host-virus arms race. Across individuals, antibodies repeatedly converge on shared solutions for capturin…
  pubmed Andrews SF, Kanekiyo M 2026 Aug 置信度 0.96 biologycomputational biologyneurosciencepsychologypharmacology
• The Imaging Compass: Navigating Reperfusion in Acute Ischemic Stroke.
  The management of acute ischemic stroke has shifted from rigid time-based protocols to imaging-driven, tissue-based reperfusion strategies. Non-contrast CT and CT angiography remain the indispensable frontline for rapid triage, particularly in community and lo…
  pubmed Xu K, Lyu J, Lou X 2026 Aug 25 置信度 0.96 medicineartificial intelligencepsychologycognitionneuroscience
• Advancements in Carbon Dot Nanozymes for Dual and Multi-Mode Biosensing of Biological and Chemical Contaminants.
  With the increasing frequency and growing complexity of food and environmental contaminants, there is a clear need for advanced sensing platforms that offer high sensitivity, rapid response times, and broad analytical applicability. Carbon dots (CDs), widely r…
  pubmed Hsu CY, Rodrigues P, Shakhmurova G, Rabbimova N 等 2026 Aug 25 置信度 0.96 nanotechnologymaterials sciencebiochemical engineeringcomputer sciencechemistry
• Drosophila Rumpelstiltskin regulates Polycomb cis and trans interactions and Homie barrier activity.
  Three-dimensional genome organization is maintained in part by chromatin insulators, DNA-protein complexes that create boundaries between active and inactive chromatin and regulate enhancer-promoter interactions. In Drosophila, the Homing insulator at eve (Hom…
  pubmed Lyda SF, McManus CE, Caravaca JM, Yang D 等 2026 Aug 6 置信度 0.96 biodiversityq-bio.gntopological insulatorspacehabitability
• Deployable high-fidelity metagenome binning at scale with QuickBin.
  Reconstructing genomes from metagenomic assemblies is foundational to microbiome research, yet binning faces a persistent trade-off between fidelity and throughput. Many high-accuracy methods rely on GPU-intensive workflows, marker-gene postprocessing, or heav…
  pubmed Bushnell B, Villada JC 2026 Aug 25 置信度 0.96 cs.aicomputer and information sciencesbenchmarkcomputer scienceq-bio.qm
• Cell-Free DNA-Based Methods to Map Chromatin.
  Cell-free DNA (cfDNA) provides a non-invasive means to monitor physiological states and diagnose diseases, with widespread applications in oncology. Our lab utilizes cfDNA as a tool to investigate the state of the tumor and the tumor microenvironment in patien…
  pubmed Eramo S, Weirich A, Ramachandran S 2026 置信度 0.96 cancercomputational biologywearable computercs.ceq-bio.qm
• Small RNA Analysis in Cancer Cells.
  Small RNAs (sRNAs), broadly defined as RNA molecules shorter than ~200 nucleotides in size, include miscellaneous products of transcription and post-transcriptional processing that are variably abundant in cancer cells. While some types of sRNAs, such as micro…
  pubmed Silva V, Kandooru S, Parrello D, Froelich B 等 2026 置信度 0.96 biologycomputational biologymicrobiologyq-bio.qmq-bio.mn
• A Comprehensive Pipeline for Long Non-Coding RNA Discovery and Characterization in Cancer.
  Long non-coding RNAs (lncRNAs) represent a significant yet underexplored component of the human genome, with emerging evidence linking them to various biological processes and diseases. Despite over 205,000 lncRNAs documented in existing databases, a substanti…
  pubmed Guda C, Jagadesan S, Veerappa A 2026 置信度 0.96 biologymedicinepsychologyneurosciencecs.lg
• A Framework for Analyzing the Epigenetic and Transcriptomic Landscape of Cancers Using Single-Cell Multiomic Data.
  Single-cell approaches to study gene regulation using multi-modal data (sc-Multiome), such as genomes, transcriptomes, and chromatin accessibility of tumor cells, offer great insights into the development trajectory. By enabling high-resolution barcoding, sing…
  pubmed Veerappa A, Guda C 2026 置信度 0.96 computational biologybiologycomputer sciencegeneticsworkflow
• Investigating the Physiological Regulation of Transposable Elements In Vivo: Nuclei Preparation from Primary Mouse Tissues for Epigenomic Analyses and Computational Approaches to Interrogate the Repeat Genome.
  Investigating the physiological regulation of the epigenome using genetically engineered mouse models, with a focus on heterochromatic regions of DNA, presents two major challenges: (i) the isolation and preparation of high-quality nuclei from tissue for analy…
  pubmed Wani SA, Wasylishen AR 2026 置信度 0.96 computational biologyq-bio.gnq-bio.mnq-bio.qmbiology
• Assay for Transposase-Accessible Chromatin Sequencing (ATAC-seq) of Cancer Cells in Culture.
  The Assay for Transposase-Accessible Chromatin followed by sequencing (ATAC-seq) is a powerful and widely-used technique for chromatin accessibility profiling due to its low input requirement, simple protocol, high sensitivity, and ability to study single cell…
  pubmed Gura K, Long T, Takaku M, Dhasarathy A 等 2026 置信度 0.96 biologycomputational biologycancerdata sciencebiological sciences
• Chromatin Immunoprecipitation Sequencing in Cancer Cells.
  Analysis of DNA co-immunoprecipitated with proteins of interest has been foundational to our understanding of chromatin and its regulation. Despite the emergence of crosslink-free techniques such as CUT&RUN and CUT&TAG, Chromatin Immunoprecipitation fo…
  pubmed Bigelow Z, Nechaev S, Dhasarathy A 2026 置信度 0.96 biologycomputational biologyq-bio.gnq-bio.qmpharmacology
• Quantitative Phenotyping of Ion Fluxes in Tip-Growing Cells Under Varying Growth Regimes: A Data Analysis Protocol.
  Tip-growing cells exhibit complex growth regimes in vitro, alternating between growing and non-growing intervals, oscillatory or more steady behavior. In Arabidopsis thaliana, pollen tube growth arrest is often accompanied by spiking behavior in intracellular …
  pubmed Portes MT, Damineli DSC, Feijó JA 2026 置信度 0.96 biologyq-bio.qmgeologyphysical sciencesq-bio.mn
• Automated Measurements of Fluorescence in Spatially Defined Regions of Pollen Tubes.
  Pollen tubes are a widely used model for the extension and development of polarized cells. Their relatively standard shape simplifies automated identification and image analysis of subregions. The key is reliable identification of the cell plasma membrane and …
  pubmed Adler J, Parmryd I 2026 置信度 0.91 astro-ph.srplasmaneuromorphic computingtokamakphysics.plasm-ph
• Examine neural network models for protein sequencing based features prediction.
  Protein functions are essential for understanding life at the molecular level. High-throughput sequencing generates vast amounts of raw protein sequences, but only about 1 percent have been carefully annotated with their functions. The experimental research ne…
  pubmed Senapati B, Das R 2026 Aug 26 置信度 0.96 cs.lgbiologycomputer scienceq-bio.qmq-bio.bm
• A power-law tailed movement created by trajectory retracing.
  Tracing specific trajectories allows a walker to revisit previous locations. However, how such local memory-based rules influence large-scale movement patterns remains unclear. In this paper, we propose a single walker model that explores a two-dimensional lat…
  pubmed Sakiyama T 2026 Aug 25 置信度 0.86 computer and information sciencescond-mat.mtrl-scics.necs.hcnetworking and internet architecture
• Predictive design of tissue-specific mammalian enhancers that function in the mouse embryo.
  Enhancers control tissue-specific gene expression across animals 1 . Although deep learning 2,3 has enabled enhancer prediction and design in mammalian cell lines and non-mammalian model organisms 4-10 (reviewed in a previous publication 11 ), it remains uncle…
  pubmed Chen S, Loubiere V, Hollingsworth EW, Murakami K 等 2026 Aug 25 置信度 0.96 cs.lgcomputational biologybiologysynthetic biologycs.ai
• Origins and consequences of oncogenic 3D chromatin remodelling.
  The 3D structure of chromatin is altered in cancer. In healthy cells, the genome is folded into functional 3D structural elements, including chromosomes, chromatin compartments, domains and loops. Cancer-associated alterations can modify each of these structur…
  pubmed Franceschini GM, Georgakopoulou K, Ciriello G, Oricchio E 2026 Aug 25 置信度 0.96 biologymedicineq-bio.gncomputational biologydisease
• Two essential criteria for transcription factor footprint discovery using V-plot.
  A recent study reported sequence biases in transcription factor (TF) footprinting data, and expressed concern about the accuracy in TF footprint discovery using V-plot analysis. Here we define two graphical parameters of V-plot as important criteria to impleme…
  pubmed Zhang Q, Xu C 2026 Aug 25 置信度 0.86 biologyinternal medicineopticsq-bio.gncomputational biology
• Explainable hybrid multi-branch CNN-ViT-GNN framework for robust hibiscus leaf disease classification.
  Early and reliable diagnosis of hibiscus leaf diseases is critical to protect horticultural yield. Yet, it remains challenging under real-time field conditions where uncontrolled lighting, clutter, and the non-contiguous nature of pathological symptoms blur di…
  pubmed Billah MM, Sagor S, Hossain S, Alahmadi TJ 等 2026 Jul 23 置信度 0.96 computer and information sciencesartificial intelligencecs.lgcs.aicomputer science
• A benchmark study of vision and pathology foundation models for computational pathology.
  To advance precision medicine in pathology, artificial intelligence (AI)-driven foundation models must generalize across diverse datasets, tissues, and clinical tasks. However, their comparative performance and generalizability in computational pathology remai…
  pubmed Bareja R, Carrillo-Perez F, Zheng Y, Pizurica M 等 2026 Jul 24 置信度 0.96 cs.lgcs.aiartificial intelligencecs.cvcs.cl
• DICER1-related tumour predisposition mutations increase 3p-miRNA function and HERVH activity.
  The DICER1 gene is mutated in cancer, including in DICER1-related tumour predisposition. Cancer-associated hotspot mutations have been reported in both catalytic domains of DICER and are predicted to disrupt miRNA biogenesis. To understand how these hotspot mu…
  pubmed Gordon K, Bellora N, Witteveldt J, Wojtus JK 等 2026 Jul 25 置信度 0.91 biologygeneticscomputational biologychemistryphysics
• Patient-partnered multiomics reveals the molecular architecture of angiosarcoma.
  Angiosarcoma is a poorly understood sarcoma due to its high heterogeneity and rarity. Here we show a comprehensive clinical and molecular analysis of a large cohort of 254 angiosarcoma patients through the patient-partnered Angiosarcoma Project. By integrating…
  pubmed Chu H, Hollyer M, Borden BA, Reilly CR 等 2026 Jul 24 置信度 0.91 medicinebiologymedlineintensive care medicinedisease
• A fully integrated smart ring for daily biochemical monitoring.
  Biochemical analysis complements biophysical measurements by capturing the underlying molecular and metabolic changes that drive physiological health. Here, we introduce a compact, fully integrated smart ring capable of simultaneously monitoring multiple chemi…
  pubmed Saha T, Ding S, Qin S, Fishman H 等 2026 Jul 23 置信度 0.96 computer sciencemedicinewearable computercomputer and information sciencesneuroimaging
• Structure-based design of stable recombinant hepatitis C virus E1E2 heterodimers.
  Hepatitis C virus (HCV) affects 47 million people and causes 239,000 deaths annually, yet no vaccine is on the horizon. Generating a stable native-like mimic of the envelope complex E1E2, the only target for known neutralizing antibodies, is an important aim f…
  pubmed Capella-Pujol J, Mulder F, Cannac F, Peters S 等 2026 Jul 23 置信度 0.96 biologycomputational biologysocial and behavioral sciencessynthetic biologychemistry
• Functional immune changes are conserved in COVID-19 and trauma patients receiving intensive care.
  Critical illness, including COVID-19 and trauma, induce immune dysregulation associated with morbidity and mortality. Direct comparison is crucial to identify shared pathobiological mechanisms to guide precision therapies. This prospective cohort study underto…
  pubmed Wood AJT, Albers GJ, Cornelissen W, Maiden JD 等 2026 Aug 25 置信度 0.96 medicinebiologyinternal medicinegeneticscancer
• Rapid minigene workflow for functional reclassification of splicing variants in hereditary cancer diagnostics.
  Next-generation sequencing of cancer predisposition genes is routinely used in hereditary cancer diagnostics. However, a substantial fraction of detected variants remains clinically unresolved. Using a customised 77-gene panel, we analysed 2142 individuals and…
  pubmed Calandra N, Mereu E, Ogliara P, Casalis Cavalchini G 等 2026 Aug 25 置信度 0.86 biologymedicinecancergeneticscell biology
• Challenges and opportunities in type III secretion system effector prediction.
  Type III secretion system effectors (T3SEs) are small bacterial proteins with big biological roles. They act as central molecular mediators of interactions between Gram-negative bacteria and eukaryotic hosts, spanning pathogenic, symbiotic and environmental co…
  pubmed Rosić I, Nikolić I 2026 Aug 26 置信度 0.96 biologycomputer sciencecomputational biologycs.aics.lg
• Tunable asymmetric swimming in biflagellate microswimmers.
  Many biological microswimmers can modulate their swimming gait to achieve directional control of motility, especially when performing steering towards specific directional cues. This can be achieved without the need for obvious morphological or structural asym…
  pubmed Walker BJ, Moreau C, Robinson TL, Xu ZJ 等 2026 Aug 26 置信度 0.96 computer and information sciencesquantum physicsphysicselectrical engineering, electronic engineering, information engineeringrobotics
• Investigating the effectiveness of multimodal data in forecasting SARS-COV-2 case surges.
  The COVID-19 pandemic response relied heavily on statistical and machine learning models to predict key outcomes such as case prevalence and fatality rates. These predictions were instrumental in enabling timely public health interventions that helped break tr…
  pubmed Raghuvamsi PV, Loh SB, Bhattacharya P, Ho J 等 2026 Aug 25 置信度 0.86 medicinescience policybiological sciences not elsewhere classifiedcs.lgbiotechnology
• Characterization of aliA and aliB deletion mutants reveals a dominant role of AliA in Haloferax volcanii lipoprotein lipidation.
  Protein lipidation is a widespread strategy for anchoring proteins to cellular membranes across all domains of life, yet the mechanisms underlying this process in archaea remain poorly understood. Recently, the first archaeal enzymes involved in lipobox-contai…
  pubmed Hong Y, Garcia A, Kopelev S, Cote JA 等 2026 Aug 25 置信度 0.96 biologymedicinebiological sciencespharmacologybiotechnology
• Spanning-tree thermostatistics of protein allostery: An exact Kirchhoff framework with application to oncogenic KRAS.
  This study introduces a statistical mechanical framework for allosteric communication in proteins based on the spanning-tree ensemble of residue contact networks. By representing Cα protein backbones as weighted graphs, we identify each spanning tree as …
  pubmed Senguler Ciftci F, Erman B 2026 Aug 25 置信度 0.96 biologydrug discoveryquant-phquantum physicscomputer and information sciences
• Evaluating the impact of antiviral post-exposure prophylaxis for health-care workers during orthoebolavirus outbreaks: a modelling study.
  Orthoebolavirus outbreaks place health-care workers (HCWs) at substantial risk, and HCW illness or death can weaken response capacity. The 2026 Bundibugyo virus outbreak in DR Congo highlights the need for deployable countermeasures when species-specific vacci…
  pubmed Stapley JN, Ko Y, Jeyapragasan G, Chan EMG 等 2026 Aug 25 置信度 0.86 climate changeai safetypopulationcomputer vision and pattern recognitiongeology
• Evaluation of the physical and radiological properties of different Fricke gel formulations as water-equivalent materials and biological tissues.
  Fricke gel dosimeters, also known as hydrogels, have emerged as attractive tools in clinical dosimetry due to the requirements of quality assurance protocols and radiation protection programs. The performance of these materials strongly depends on the characte…
  pubmed Dos Santos AMM, Araújo LF, Costa L, Araujo N 等 2026 Aug 25 置信度 0.96 materials sciencenanotechnologychemistrycond-mat.mtrl-scibiology
• Spatial profiling of the spleen in mouse and human myelofibrosis reveals complement-driven immune-stromal interactions as a therapeutic target.
  Splenomegaly is a defining feature of myelofibrosis, yet the contribution of splenic mesenchymal stroma to disease progression remains unclear. We combined spatial and single-nucleus transcriptomics of patient spleens with spatial and single-cell transcriptomi…
  pubmed Dugué B, Wanner P, Ruiz Tejada Segura ML, Saad M 等 2026 Aug 25 置信度 0.96 biologymedicinecancercell biologydisease
• 16α-Hydroxydehydrotrametenolic acid attenuates MDA-MB-231 triple-negative breast cancer xenograft growth and modulates integrin β1/c-Met signaling and glycolytic metabolism.
  Abnormal glycolysis, enhanced metastatic potential, and dysregulated oncogenic signaling, including integrin β1 and c-Met pathways, are key drivers of triple-negative breast cancer (TNBC) progression and contribute to its poor prognosis and limited thera…
  pubmed Wu N, Luo Y, Quan Q, Huang X 等 2026 Aug 19 置信度 0.86 medicinepharmacologycancerinternal medicinebiochemistry
• Purine-centred fused, conformationally constrained, and ring-expanded analogues in antitumor and antiviral drug discovery: A comprehensive review.
  Purine-derived scaffolds remain important in anticancer and antiviral drug discovery because their electronic properties, hydrogen-bonding capacity, and conformational adaptability support interactions with kinases, polymerases, nucleotide-processing enzymes, …
  pubmed Nidhar M, Alam P, Alqarni MH, Foudah AI 等 2026 Aug 21 置信度 0.96 nanotechnologybiotechnologymedicinepharmacologymaterials science
• Multidimensional interactions of living materials with biological entities.
  Living materials, defined by dynamic biological activity and responsive capabilities, are emerging as pivotal therapeutic agents in biomedicine. Their therapeutic effects are driven by active interactions with biological entities at multiple levels. However, m…
  pubmed Du S, Liu Y, Liu Y, Tan Y 等 2026 Aug 20 置信度 0.96 biotechnologymedicineneurosciencebiologyscience policy
• Logic-gated nanoregulators: A paradigm shift from drug delivery to pre-programmed multi-target immunotherapy.
  Cancer immunotherapy has reshaped oncology, yet its broad application is constrained by an immunosuppressive tumor microenvironment and the systemic toxicities of conventional treatments. This review traces the evolution of nanomedicine from a passive drug del…
  pubmed Wu Y, Tang F, Lee J, Liang Y 等 2026 Aug 17 置信度 0.96 biologyai governancepharmacologyartificial intelligenceai safety
• Longitudinal inference of hippocampal volume and morphometric hippocampal-cortical covariance in psychosis.
  Schizophrenia and related psychoses are characterized by reductions in hippocampal volume and morphometric hippocampal-cortical covariance. No study to date has inferred the temporal relationship between deviations in subfield and adjacent white matter volume …
  pubmed Totzek JF, Heckers S, Palaniyappan L, Young AL 等 2026 Aug 6 置信度 0.86 psychologymedicineneuroscienceinternal medicineneuroimaging
• Physical and mental health among seasonal migrant farmworkers: Evidence from a survey conducted in northwestern Italy.
  Farmworkers exhibit a higher prevalence of musculoskeletal disorders, levels of anxiety, depression, and work-related stress compared with general population. However, few studies have investigated the main predictors of these outcomes. Therefore, this study a…
  pubmed Sodano B, Catalano A, Avanzi S, Gebru KT 等 2026 Aug 25 置信度 0.93 medicinepsychological interventioninternal medicinemedlinepsychology
• Trace element-based Co(II) and Fe(III) mixed-ligand complexes of phenanthroline and sulfasalazine: Structural, DFT, molecular docking, and antimicrobial studies.
  New mixed ligand compounds FeSUPT and CoSUPT were successfully prepared using sulfasalazine (SU) and phenanthroline (PT). The compounds were recovered as solid, non-electrolyte substances with good thermal stability (above 300°C) and low molar conductivit…
  pubmed Khalaf MM, Abd El-Lateef HM, Eltayeb H, Abdou A 2026 Aug 20 置信度 0.96 chemistrymaterials sciencemedicinebiochemistrybiology
• Can 18F-FDG PET/CT SUV(max) values predict breast and axillary pathological complete response before neoadjuvant chemotherapy in breast cancer?
  We aimed to investigate whether maximum standardized uptake value (SUV max ) values of breast mass and axilla metastatic lymph nodes are effective independent predictive factors for breast and axillary pathological complete response (PCR) before neoadjuvant ch…
  pubmed Koca B, Yildirim M, Saglam AI, Ozsoy U 2026 置信度 0.93 taxonomyai governanceclimatologyphysics.geo-phai safety
• Metabolomics of Eryngium heterophyllum by UHPLC-QToF-MS and In Silico Insights Into Potential Metabolic Syndrome Targets.
  Eryngium heterophyllum (toad grass) is native to Mexico and has been used traditionally to manage diabetes, hypercholesterolemia, and arthritis. However, its bioactive compounds remain poorly characterized. This study profiled the phytochemical composition of …
  pubmed Gutiérrez-Rodelo C, Galván LEM, Estrada-Lugo E, Avula B 等 2026 Aug 置信度 0.96 medicinebiotechnologypharmacologygeneticsbiochemistry
• Identification of candidate macrophage-ferroptosis crosstalk genes associated with immune infiltration in myocardial infarction: A bioinformatics analysis.
  Globally, myocardial infarction (MI) remains a major cause of morbidity and mortality. Macrophage-mediated inflammation and ferroptosis-related stress responses have both been implicated in MI; however, transcriptomic identification of macrophage- and ferropto…
  pubmed Wang G, Zhang Z, Yang G, Wang J 等 2026 置信度 0.86 medicinebiologycancerbiotechnologyinternal medicine
• High reelin expression may explain why a subgroup of entorhinal cortex neurons functions as an initial nucleation site of Alzheimer's disease.
  The entorhinal cortex (EC) plays a crucial role in memory functions. Long before the clinical symptoms of Alzheimer's disease (AD) emerge, it has already undergone significant degeneration, making it a primary site for the onset of the disease. The reasons for…
  pubmed Kobro-Flatmoen A, Hussan JR, Hunter PJ, Omholt SW 2026 Aug 置信度 0.96 neurosciencebiologygeologydiseasemeteorite
• Theory and evidence of amplitude control by frequency detuning in a coupled neuronal oscillator system.
  Neuronal oscillator circuits that generate rhythmic movements must operate flexibly and reliably to produce the varied motor patterns that animals exhibit naturally. Rodents rhythmically "whisk" their vibrissae for haptic perception, and they dynamically adjus…
  pubmed Lu AC, Ourang SA, Moore JD 2026 Aug 25 置信度 0.96 neuroscienceq-bio.mncs.etcomputer and information sciencesbrain-computer interface
• A unified CPG-based and multi-agent control framework for low-cost quadruped robots.
  Quadruped robots have gained significant attention due to their superior mobility on uneven and unstructured terrains, offering potential applications in inspection, search and rescue, and field exploration. However, achieving robust locomotion on low-cost pla…
  pubmed Wu L, Zhang M, Wang W 2026 置信度 0.96 computer and information sciencesroboticselectrical engineering, electronic engineering, information engineeringcs.rocomputer science
• The multi-omics fallacy in microbiome science.
  Artificial intelligence and machine-learning-assisted multi-omics have expanded the scale and ambition of microbiome research, but they have also sharpened an older interpretive problem. Biologically plausible structure is too easily mistaken for biological ex…
  pubmed Lewandowski R 2026 Aug 置信度 0.96 artificial intelligencecomputer sciencepsychologymedicinebiology
• A decade of artificial intelligence research in ophthalmology: Global trends and transferable insights for medical AI.
  To characterize global trends in ophthalmic AI research from 2015-2025 and drive transferable insights into the broader evolution of AI in medicine, we conducted a systematic bibliometric analysis of original AI articles in ophthalmology indexed in the Web of …
  pubmed Fan Z, Qin Y, Chen L, Yuan J 等 2026 Aug 置信度 0.96 medicinescience policypsychologymedlinedata science
• Community-driven updates for comprehensive long-read metagenomics and enhanced binning in nf-core/mag v5.
  nf-core/mag is a reproducible Nextflow pipeline for best-practice metagenomic de novo assembly, and binning within the nf-core framework. Here we present a major update that adds support for long-read-only assembly and bin refinement, includes five new binning…
  pubmed Alvarez Saravia D, Rosenbaum A, Straub D, Downie J 等 2026 Aug 25 置信度 0.91 ai governancebiologyai safetycomputational biologymulti-agent systems
• Morphing active networks.
  Biological networks like leaf venation exhibit remarkable morphing capabilities that enable organisms to adapt and thrive in their environments. However, the underlying mechanisms that govern the morphing of such networks, especially when the network itself ac…
  pubmed Wen Y, Chen Y, Yang Y, Xu F 2026 Sep 置信度 0.96 computer and information sciencescs.lgneurosciencenetworking and internet architectureartificial neural network
• Overview of exosomal non-coding RNAs in cardiovascular disease using high throughput sequencing.
  Non-coding RNAs including miRNAs, long-ncRNAs, and circular RNAs play crucial roles in cell-to-cell communication and epigenetic regulation. They control gene expression at multiple levels, including transcriptional, post-transcriptional, and translational, th…
  pubmed Eivazi M, Abkhooie L, Hosseini K, Mobasheran P 等 2025 Nov 15 置信度 0.96 medicinebiologyneurosciencebiotechnologynanotechnology
• Single-Cell Glycomics of the Pancreatic Tumor Microenvironment: Technologies, Glyco-Immune Checkpoints, and Tumor-Immune Communication.
  In this Review, we summarize recent conceptual and technological advances in single-cell glycomics, with a particular focus on emerging strategies that enable glycan-resolved analysis of tumor-immune interactions. We highlight single-cell glycan and RNA sequen…
  pubmed Anh DXT, Tateno H 2026 Aug 置信度 0.96 biologycomputational biologysynthetic biologycomputer and information sciencesbiological sciences not elsewhere classified