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precision medicine

GeneTech 知识引擎共收录 115 篇相关科研实体，横跨 17 个垂直领域。数据来自 OpenAlex、arXiv、Crossref、PubMed、Europe PMC 等公开学术源，全部可溯源到原文。

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代表性文献（按质量分排序，前 60 条）

• Multi-omics and artificial intelligence for precision drug discovery and potential clinical applications
  2026 · AI 安全与对齐 · The integration of multiomics technologies with artificial intelligence (AI) has become a transformative force in modern precision medicine, particularly within drug discovery. Multiomics approaches, including genome-wid…
• AI/ML-enabled multi-omics integration of host genetics, immunity, and the gut microbiome in Crohn’s disease: From diagnosis to theranostics
  2026 · AI 安全与对齐 · Crohn's disease is a long-term inflammatory disorder arising from the interaction of genetic risk factors, immune system dysfunction, and alterations in gut microbiota. Variability in clinical phenotypes and lack of biom…
• Artificial Intelligence Drives Advances in Multi-Omics Analysis and Precision Medicine for Sepsis
  2026 · 医疗人工智能 · Sepsis is a life-threatening syndrome characterized by marked clinical heterogeneity and complex host-pathogen interactions. Although traditional mechanistic studies have identified key molecular pathways, they remain in…
• Artificial Intelligence Applications in Gastric Cancer Surgery: Bridging Early Diagnosis and Responsible Precision Medicine
  2026 · 医疗人工智能 · Background: Artificial intelligence is emerging as a promising tool in surgical oncology, with growing evidence suggesting potential applications in diagnostic support, intraoperative guidance, and perioperative risk ass…
• Artificial intelligence to investigate metabolomics data for precision medicine
  2026 · 医疗人工智能 · BACKGROUND: Metabolomic data offers insights into disease mechanisms, diagnostics, and therapeutic targets by analyzing metabolic profiles. In analyzing these profiles, traditional bioinformatic and statistical approache…
• Artificial intelligence for breast cancer management
  2026 · 医疗人工智能 · Artificial intelligence is transforming breast cancer management through various machine learning applications. Artificial intelligence supports precision medicine by enhancing detection, diagnosis, prognosis, and treatm…
• Toward Timely Diagnosis of Pancreatic Cancer: Revolutionizing Early Detection Through Genomics, Artificial Intelligence, and Noninvasive Biomarkers
  2026 · 医疗人工智能 · BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive cancers, typically diagnosed at an advanced stage due to its subtle and often absent early symptoms. Despite representing only 3% of …
• From 2D cultures to 3D systems: evolving cancer models at the interface of functional precision medicine and theranostics
  2026 · 仿生智能 · Advances in patient-derived cancer models are pushing precision oncology by linking functional testing directly to therapeutic decision-making.Traditional two-dimensional (2D) cancer cell culture systems have long served…
• Shaping the future of multiple myeloma with artificial intelligence and digital twins: from concept to clinic
  2026 · 数字孪生 · Multiple myeloma (MM) is an incurable hematological malignancy with significant clinical and biological heterogeneity. Despite development and refinement of numerous prognostic models for MM, challenges with accurate and…
• Digital twins in oncology: From predictive modelling to personalised treatment strategies.
  2026 · 数字孪生 · The digital twin (DT) concept, originating from engineering disciplines, has emerged as a transformative technology in healthcare, particularly in oncology. A digital twin creates a dynamic, virtual replica of a patient'…
• Digital twin technologies in prostate cancer as a frontier for precision medicine.
  2026 · 数字孪生 · Prostate cancer (PCa) is the most frequently diagnosed malignancy among men and presents major clinical and socioeconomic challenges worldwide. Despite advances in early detection, imaging, and therapy, managing PCa rema…
• From images to physics-based computational models to digital twins: a framework for personalized cancer therapies
  2026 · 数字孪生 · In this work, we highlight recent advances in computational modeling that have significantly enhanced prospects of personalized cancer therapies by enabling insightful integration of patient-specific data, including medi…
• Digital twins in oncology: Revolutionising precision cancer care
  2026 · 数字孪生 · The emergence of digital twin technology represents a paradigm shift in precision oncology, offering unprecedented opportunities to transform how we diagnose, treat, and monitor cancer patients. Originally conceived in a…
• From equations to agents: The artificial intelligence virtual cell reshaping precision oncology
  2026 · 数字孪生 · The Artificial Intelligence Virtual Cell (AIVC) is an advanced computational tool that combines detailed cellular data from single-cell and spatial technologies, including gene expression, epigenetic changes, and cell ch…
• The Digital Frontier: A Narrative Review of Bio-Digital Twins, AI-Driven Orthodontics, and Ethical Clinical Integration
  2026 · 数字孪生 · The transition from static digital records to dynamic Bio-Digital Twins is reshaping orthodontics by combining anatomical and functional data to simulate physiological behavior and improve diagnostic accuracy. This narra…
• Digital twins in precision pharmacotherapy: emerging applications, challenges, and future directions
  2026 · 数字孪生 · Digital twin technology, defined as dynamic digital models that represent individual patients, is emerging as a promising paradigm in precision pharmacotherapy. The integration of pharmacokinetic and pharmacodynamic (PK/…
• HOST–PATHOGEN INTERACTIONS IN TUBERCULOSIS: A MULTI-OMICS AND ARTIFICIAL INTELLIGENCE PERSPECTIVE
  2026 · 基因技术工具 · Published journal article: Host–Pathogen Interactions in Tuberculosis: A Multi-Omics and Artificial Intelligence Perspective. This review discusses recent advances in understanding host–pathogen interactions in tuberculo…
• HOST–PATHOGEN INTERACTIONS IN TUBERCULOSIS: A MULTI-OMICS AND ARTIFICIAL INTELLIGENCE PERSPECTIVE
  2026 · 基因技术工具 · Published journal article: Host–Pathogen Interactions in Tuberculosis: A Multi-Omics and Artificial Intelligence Perspective. This review discusses recent advances in understanding host–pathogen interactions in tuberculo…
• Evaluating the Cost of Genomic Testing for Biomarker-Driven Therapies in Oncology
  2026 · 基因技术工具 · INTRODUCTION: Genomic profiling is used in the diagnosis, monitoring, and treatment of malignancies. Comprehensive genomic profiling (CGP) is a next-generation sequencing (NGS) approach that can test multiple genes simul…
• HCS-3DX, a next-generation AI-driven automated 3D-oid high-content screening system
  2025 · AI 安全与对齐 · Self-organised three-dimensional (3D) cell cultures, collectively called 3D-oids, include spheroids, organoids and other co-culture models. Systematic evaluation of these models forms a critical new generation of high-co…
• Breast cancer: pathogenesis and treatments
  2025 · AI 安全与对齐 · Breast cancer, characterized by unique epidemiological patterns and significant heterogeneity, remains one of the leading causes of malignancy-related deaths in women. The increasingly nuanced molecular subtypes of breas…
• Transforming sepsis management: AI-driven innovations in early detection and tailored therapies
  2025 · AI 安全与对齐 · Sepsis remains a leading cause of mortality worldwide, driven by its clinical complexity and delayed recognition. Artificial intelligence (AI) offers promising solutions to improve sepsis care through earlier detection, …
• Quantum computing and the implementation of precision medicine.
  2025 · 生物计算 · Precision medicine aims to tailor healthcare by integrating individual genetic, epigenetic, transcriptomic, proteomic, and clinical data, collectively referred to as multi-omic data. However, the scale and complexity of …
• AI-driven multi-omics integration in precision oncology: bridging the data deluge to clinical decisions
  2025 · 生物计算 · Cancer's staggering molecular heterogeneity demands innovative approaches beyond traditional single-omics methods. The integration of multi-omics data, spanning genomics, transcriptomics, proteomics, metabolomics and rad…
• Artificial intelligence in oncology drug development and management: a precision medicine perspective
  2025 · 医疗人工智能 · The management of oncology drugs is inherently complex, facing challenges such as high development costs, prolonged timelines, and substantial inter-patient heterogeneity. Recent advances in artificial intelligence (AI) …
• A Narrative Review of Theranostics in Neuro-Oncology: Advancing Brain Tumor Diagnosis and Treatment Through Nuclear Medicine and Artificial Intelligence
  2025 · 医疗人工智能 · This narrative review explores the integration of theranostics and artificial intelligence (AI) in neuro-oncology, addressing the urgent need for improved diagnostic and treatment strategies for brain tumors, including g…
• Artificial Intelligence in healthcare: Transformative applications, ethical challenges, and future directions in medical diagnostics and personalized medicine
  2025 · 医疗人工智能 · The harmonization of Artificial Intelligence (AI) in the healthcare sector has revolutionized medical diagnostics, treatment planning, and patient management. Over the past decade, AI-powered technologies have demonstrat…
• Artificial Intelligence in Glioblastoma—Transforming Diagnosis and Treatment
  2025 · 医疗人工智能 · Glioblastoma (GBM) is the most aggressive and common primary brain malignancy in adults, characterized by poor prognosis and treatment resistance. Despite advancements in treatment options, the median survival is roughly…
• Artificial intelligence for precision medicine
  2025 · 医疗人工智能 · INTRODUCTION: Precision medicine aims to tailor healthcare decisions and interventions to the unique biological and clinical characteristics of each patient. The recent convergence of artificial intelligence (AI) with ad…
• Integrating artificial intelligence in healthcare: applications, challenges, and future directions
  2025 · 医疗人工智能 · Artificial intelligence (AI) has demonstrated remarkable potential in transforming medical diagnostics across various healthcare domains. This paper explores AI applications in cancer detection, dental medicine, brain tu…
• Artificial Intelligence-Powered Quality Assurance: Transforming Diagnostics, Surgery, and Patient Care—Innovations, Limitations, and Future Directions
  2025 · 医疗人工智能 · Artificial intelligence is rapidly transforming quality assurance in healthcare, driving advancements in diagnostics, surgery, and patient care. This review presents a comprehensive analysis of artificial intelligence in…
• Artificial Intelligence Applications in the Diagnosis, Treatment, and Prognosis of Hepatocellular Carcinoma
  2025 · 医疗人工智能 · The global burden of hepatocellular carcinoma (HCC) has shifted from viral to nonviral etiologies. However, successful antiviral therapy does not fully eliminate the risk of HCC, underscoring the demand for more effectiv…
• The role of artificial intelligence in cardiovascular research: Fear less and live bolder
  2025 · 医疗人工智能 · BACKGROUND: Artificial intelligence (AI) has captured the attention of everyone, including cardiovascular (CV) clinicians and scientists. Moving beyond philosophical debates, modern cardiology cannot overlook AI's growin…
• Next-Generation Advances in Prostate Cancer Imaging and Artificial Intelligence Applications
  2025 · 医疗人工智能 · Prostate cancer is one of the leading causes of cancer-related morbidity and mortality worldwide, and imaging plays a critical role in its detection, localization, staging, treatment, and management. The advent of artifi…
• Applications of artificial intelligence in non–small cell lung cancer: from precision diagnosis to personalized prognosis and therapy
  2025 · 医疗人工智能 · BACKGROUND: Non-small cell lung cancer (NSCLC) carries a major global burden. The rapid growth of multimodal medical data challenges conventional methods to deliver stable, transferable and interpretable decisions across…
• Precision therapies for genetic epilepsies in 2025: Promises and pitfalls
  2025 · 脑科学 · By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug-resistant epilepsies, including developmental and epileptic encephalopathies. Unlike con…
• AI reshaping life sciences: intelligent transformation, application challenges, and future convergence in neuroscience, biology, and medicine
  2025 · 脑科学 · The rapid advancement of artificial intelligence (AI) is profoundly transforming research paradigms and clinical practices across neuroscience, biology, and medicine with unprecedented depth and breadth. Leveraging its r…
• Comparative analysis on AI-driven human digital twin for personalized and predictive medicine
  2025 · 数字孪生 · The emergence of digital twin technology in medicine signifies a paradigm shift toward personalized healthcare and precision therapeutics. A human digital twin (HDT) is a dynamic, virtual representation of an individual’…
• Integrating Precision Medicine and Digital Health in Personalized Weight Management: The Central Role of Nutrition
  2025 · 数字孪生 · Obesity is a global health challenge marked by substantial inter-individual differences in responses to dietary and lifestyle interventions. Traditional weight loss strategies often overlook critical biological variation…
• Digital Twins for Precision Oncology: Modelling Foundations, Clinical Applications, and Open Challenges
  2025 · 数字孪生 · The field of digital twins (DT) is a rapidly expanding area in healthcare. Although DTs have long been established in engineering and military contexts, their adoption in medicine remains in its infancy. However, in canc…
• The translational power of Alzheimer’s-based organoid models in personalized medicine: an integrated biological and digital approach embodying patient clinical history
  2025 · 数字孪生 · Alzheimer’s disease (AD) is a complex neurodegenerative condition characterized by a multifaceted interplay of genetic, environmental, and pathological factors. Traditional diagnostic and research methods, including neur…
• The clinical application of artificial intelligence in cancer precision treatment
  2025 · 边缘智能 · BACKGROUND: Artificial intelligence has made significant contributions to oncology through the availability of high-dimensional datasets and advances in computing and deep learning. Cancer precision medicine aims to opti…
• Artificial intelligence entering the pathology arena in oncology: current applications and future perspectives
  2025 · 边缘智能 · BACKGROUND: Artificial intelligence (AI) is rapidly transforming the fields of pathology and oncology, offering novel opportunities for advancing diagnosis, prognosis, and treatment of cancer. METHODS: Through a systemat…
• Precision Neuro-Oncology in Glioblastoma: AI-Guided CRISPR Editing and Real-Time Multi-Omics for Genomic Brain Surgery
  2025 · 基因技术工具 · Precision neurosurgery is rapidly evolving as a medical specialty by merging genomic medicine, multi-omics technologies, and artificial intelligence (AI) technology, while at the same time, society is shifting away from …
• Quantum computing and the implementation of precision medicine.
  2025 · 量子计算 · Precision medicine aims to tailor healthcare by integrating individual genetic, epigenetic, transcriptomic, proteomic, and clinical data, collectively referred to as multi-omic data. However, the scale and complexity of …
• Advancing protein biosensors: redefining detection through innovations in materials, mechanisms, and applications for precision medicine and global diagnostics
  2025 · 量子材料 · Protein biosensors are significant tools in modern diagnostics due to their exceptional sensitivity and specificity in detecting protein biomarkers critical for disease diagnosis, therapeutic monitoring, and biomedical r…
• Personalized cancer vaccine design using AI-powered technologies
  2024 · AI 驱动科学发现 · Immunotherapy has ushered in a new era of cancer treatment, yet cancer remains a leading cause of global mortality. Among various therapeutic strategies, cancer vaccines have shown promise by activating the immune system…
• Integrating Big Data, Artificial Intelligence, and motion analysis for emerging precision medicine applications in Parkinson’s Disease
  2024 · 医疗人工智能 · One of the key challenges in Big Data for clinical research and healthcare is how to integrate new sources of data, whose relation to disease processes are often not well understood, with multiple classical clinical meas…
• Applications of Multimodal Artificial Intelligence in Non-Hodgkin Lymphoma B Cells
  2024 · 医疗人工智能 · Given advancements in large-scale data and AI, integrating multimodal artificial intelligence into cancer research can enhance our understanding of tumor behavior by simultaneously processing diverse biomedical data type…
• Artificial Intelligence in IVF Laboratories: Elevating Outcomes Through Precision and Efficiency
  2024 · 医疗人工智能 · Incorporating artificial intelligence (AI) into in vitro fertilization (IVF) laboratories signifies a significant advancement in reproductive medicine. AI technologies, such as neural networks, deep learning, and machine…
• Shareable artificial intelligence to extract cancer outcomes from electronic health records for precision oncology research
  2024 · 医疗人工智能 · Databases that link molecular data to clinical outcomes can inform precision cancer research into novel prognostic and predictive biomarkers. However, outside of clinical trials, cancer outcomes are typically recorded on…
• Enhancing Oral Cancer Detection: A Systematic Review of the Diagnostic Accuracy and Future Integration of Optical Coherence Tomography with Artificial Intelligence
  2024 · 医疗人工智能 · Introduction: Optical Coherence Tomography (OCT) has emerged as an important imaging modality in non-invasive diagnosis for oral cancer and can provide real-time visualisation of tissue morphology with the required high …
• The Application of Knowledge Engineering via the Use of a Biomimetic Digital Twin Ecosystem, Phenotype-Driven Variant Analysis, and Exome Sequencing to Understand the Molecular Mechanisms of Disease
  2024 · 数字孪生 · Applied artificial intelligence, particularly large language models, in biomedical research is accelerating, but effective discovery and validation requires a toolset without limitations or bias. On January 30, 2023, the…
• Artificial Intelligence (AI) Applications in Drug Discovery and Drug Delivery: Revolutionizing Personalized Medicine
  2024 · 数字孪生 · Artificial intelligence (AI) encompasses a broad spectrum of techniques that have been utilized by pharmaceutical companies for decades, including machine learning, deep learning, and other advanced computational methods…
• Generative artificial intelligence empowers digital twins in drug discovery and clinical trials
  2023 · 医疗人工智能 · INTRODUCTION: The concept of Digital Twins (DTs) translated to drug development and clinical trials describes virtual representations of systems of various complexities, ranging from individual cells to entire humans, an…
• Artificial Intelligence in Andrology: From Semen Analysis to Image Diagnostics
  2023 · 医疗人工智能 · Artificial intelligence (AI) in medicine has gained a lot of momentum in the last decades and has been applied to various fields of medicine. Advances in computer science, medical informatics, robotics, and the need for …
• Toward Explainable Artificial Intelligence for Precision Pathology
  2023 · 医疗人工智能 · The rapid development of precision medicine in recent years has started to challenge diagnostic pathology with respect to its ability to analyze histological images and increasingly large molecular profiling data in a qu…
• Artificial Intelligence in Brain Tumor Imaging: A Step toward Personalized Medicine
  2023 · 仿生智能 · The application of artificial intelligence (AI) is accelerating the paradigm shift towards patient-tailored brain tumor management, achieving optimal onco-functional balance for each individual. AI-based models can posit…
• Connecting the dots towards precision orthodontics
  2023 · 数字孪生 · Precision orthodontics entails the use of personalized clinical, biological, social and environmental knowledge of each patient for deep individualized clinical phenotyping and diagnosis combined with the delivery of car…
• Current Status of Cancer Genomics and Imaging Phenotypes: What Radiologists Need to Know
  2023 · 基因技术工具 · Ongoing discoveries in cancer genomics and epigenomics have revolutionized clinical oncology and precision health care. This knowledge provides unprecedented insights into tumor biology and heterogeneity within a single …

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