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• Advances in the use of morphogenic regulators and peptide regenerating factors for boosting plant transformation and genome editing.
  europepmc 2026 置信度 0.80
• Modulating the cleavage and polyadenylation site: from research tools to therapeutic opportunities.
  europepmc 2026 置信度 0.80
• Advances in molecular breeding of medicinal plants.
  europepmc 2026 置信度 0.80
• Gene-sized editing for the therapy of genetic diseases.
  europepmc 2026 置信度 0.80
• CRISPR-Based Therapy for Ischemic Stroke: A Narrative Review.
  europepmc 2026 置信度 0.80
• Loss of U11/U12 spliceosome gene <i>ZCRB1</i> leads to aberrant ciliogenesis and WNT signaling.
  europepmc 2026 置信度 0.80
• Targeting Myostatin for Sustainable Meat Production: Insights From Multiple Species.
  europepmc 2026 置信度 0.80
• Improvement of chicken genome editing efficiency in vitro using ribonucleoprotein-mediated CRISPR/Cas9 delivery.
  europepmc 2026 置信度 0.80
• Human pluripotent stem cell engineering with CRISPR-Cas9 for Parkinson's disease.
  europepmc 2026 置信度 0.80
• Generation of a FRMD5 knockout human embryonic stem cell line by CRISPR/Cas9 editing.
  europepmc 2026 置信度 0.80
• The evolving landscape of gene editing therapies for human genetic diseases: a twenty-year bibliometric analysis.
  europepmc 2026 置信度 0.80
• Emerging trends in genome editing of wild animals.
  europepmc 2026 置信度 0.80
• Metabolic engineering strategies for optimized lignan production in plants.
  europepmc 2026 置信度 0.80
• Exploring gene editing as a potential therapeutic strategy for hemophilia.
  europepmc 2026 置信度 0.80
• Visual detection platform based on RPA-CRISPR/Cas12a for Klebsiella pneumoniae and Carbapenem-resistant Klebsiella pneumoniae in clinical and food safety settings.
  europepmc 2026 置信度 0.80
• Transgene-free genome editing in citrus and poplar meristem tissues via biolistic ribonucleoprotein delivery of CRISPR-Cas9.
  europepmc 2026 置信度 0.80
• Engineering next-generation crops through CRISPR-mediated horizontal gene transfer.
  europepmc 2026 置信度 0.80
• Topical application of Cas9 ribonucleoproteins inhibits corneal neovascularization in a mouse model of alkali burn injury.
  europepmc 2026 置信度 0.80
• Plant microbiome engineering: from inoculation to genome editing.
  Plant-associated microbiomes are central to crop productivity, nutrient efficiency, and stress resilience, yet conventional microbiome manipulation strategies, largely based on microbial inoculation and agronomic management, often suffer from inconsistent fiel…
  europepmc 2026 置信度 0.80
• The Effector SIX8 Contributes to Virulence of Fusarium oxysporum f. sp. lactucae Race 4 on Lettuce.
  europepmc 2026 置信度 0.80
• Research progress on cold tolerance key genes and mechanisms in four major northern China crops.
  europepmc 2026 置信度 0.80
• Detection of duck adenovirus 3 using RAA-CRISPR/Cas12a based lateral flow dipstick method.
  europepmc 2026 置信度 0.80
• CRISPR-Cpf1-Mediated Gene-Editing System Based on a Single Bidirectional Promoter.
  europepmc 2026 置信度 0.80
• Non-Viral CRISPR carriers: transient delivery with lasting effects.
  europepmc 2026 置信度 0.80
• Literature horizon scan for new scientific data on plants, microorganisms and animals, and their products obtained by new genomic techniques (October 2025).
  europepmc 2026 置信度 0.80
• CRISPR-screen informed engineered T cell therapies.
  europepmc 2026 置信度 0.80
• Optimization of Agrobacterium-mediated transformation of commercial heirloom tomato cultivars to develop novel traits via CRISPR/Cas9 genome editing.
  europepmc 2026 置信度 0.80
• Genetically Modified Plants in Agriculture.
  europepmc 2026 置信度 0.80
• Assessing off-target effects in CRISPR/Cas9: challenges and strategies for precision DNA editing.
  The emergence of CRISPR/Cas9 technology has transformed the landscape of gene editing, allowing for precise alterations in DNA that hold great promise for research and potential therapies. However, a significant concern is the occurrence of off-target effects,…
  europepmc 2026 置信度 0.80
• Evaluation of Bna.SCT and Bna.REF1 as Target Genes to Reduce Sinapine in Rapeseed Using a Protoplast-Based CRISPR RNP Approach.
  europepmc 2026 置信度 0.80
• Nanocarrier-mediated CRISPR-Cas delivery: a novel approach against antibiotic-resistant superbugs.
  europepmc 2026 置信度 0.80
• Multiplexed CRISPR base editing enables pulse-activated irreversible biocontainment of engineered bacteria.
  europepmc 2026 置信度 0.80
• A heterologous marker-free selection approach for CRISPR/Cas9-based gene editing in the malaria parasite <i>Plasmodium falciparum</i>.
  europepmc 2026 置信度 0.80
• Genetic medicines for epilepsy: unlocking new avenues for seizure control.
  europepmc 2026 置信度 0.80
• Evaluating the scientific and regulatory case for the deployment of the radioresistant genus <i>Deinococcus</i> in bioremediation.
  europepmc 2026 置信度 0.80
• An AI-driven framework for enhancing regulatory precision and efficiency in CRISPR-Cas gene-edited crops: challenges, opportunities, and global harmonization.
  europepmc 2025 置信度 0.80
• Topic "Application of Reproductive and Genomic Biotechnologies for Livestock Breeding and Selection".
  europepmc 2026 置信度 0.80
• Conjugation as an evolutionary bottleneck in antimicrobial resistance spread.
  europepmc 2026 置信度 0.80
• Features affecting Cas9-induced editing efficiency and patterns in tomato: evidence from a large CRISPR dataset.
  europepmc 2026 置信度 0.80
• The future of reproduction in Eve Smith's <i>Off Target</i> and Kira Peikoff's <i>Baby X</i>.
  europepmc 2026 置信度 0.80
• Virus-induced genome editing enables functional genomics across diverse plant species.
  europepmc 2026 置信度 0.80
• Engineering plant architecture in the ornamental species Eustoma grandiflorum by knockout of strigolactone biosynthesis.
  europepmc 2026 置信度 0.80
• Induced pluripotent stem cells as platforms for engineering NK cell immunotherapies.
  europepmc 2026 置信度 0.80
• A rapid Agrobacterium rhizogenes-mediated transient expression for assessing sgRNA efficiency in CRISPR-Act3.0 in tomato.
  europepmc 2026 置信度 0.80
• The CRISPR-Cas toolkit for mosquito-borne virus surveillance: detection, tracing, and discovery.
  europepmc 2026 置信度 0.80
• A versatile VLP-mediated CRISPR-RNP platform for precise genome editing and durable epigenome silencing in cancer.
  europepmc 2026 置信度 0.80
• CRISPR-Cas-Mediated Reprogramming Strategies to Overcome Antimicrobial Resistance.
  europepmc 2026 置信度 0.80
• Global Research Trends and Hotspots in Gene Editing and Stem Cell Therapies for Neurodegenerative Diseases: Bibliometric and Visualization Analysis.
  europepmc 2026 置信度 0.80
• CRISPR-Cas9-based gene editing as a proof-of-concept approach in an inborn error of immunity caused by a DCLRE1C variant.
  europepmc 2026 置信度 0.80
• CRISPR and the Future of Cardiac Disease Therapy: A New Genetic Frontier.
  europepmc 2026 置信度 0.80
• The dynamic interplay between <i>Staphylococcus pseudintermedius</i> and canine immunity: mechanisms of pathogenesis, evasion, and vaccination perspectives.
  europepmc 2026 置信度 0.80
• Genomic profiling of ESBL/AmpC-producing <i>Escherichia coli</i> from backyard poultry: resistome, virulome, plasmidome, and CRISPR-Cas insights.
  europepmc 2026 置信度 0.80
• Emerging therapies for type 1 diabetes: Immunotherapy and gene editing advances.
  europepmc 2026 置信度 0.80
• Cytosolic localization of MBL-1/Muscleblind may be required for ectopic neurite outgrowth in a sensitized background in <i>C. elegans</i>.
  europepmc 2026 置信度 0.80
• Commentary: CRISPR-Cas systems against carbapenem resistance-from proof-of-concept to clinical translation.
  europepmc 2026 置信度 0.80
• Advances in Double-Stranded DNA Targeting Technologies.
  europepmc 2026 置信度 0.80
• Double-CRISPR Knockout Simulation (DKOsim): A Monte-Carlo randomization system to model cell growth behavior and infer the optimal library design for growth-based double knockout screens.
  europepmc 2026 置信度 0.80
• Functional analysis of genes enriched in male reproductive organs: validation via fertility assessment of 14 knockout mouse lines.
  europepmc 2026 置信度 0.80
• Advances and prospects of genomic-assisted breeding in roots, tubers, and banana crops.
  europepmc 2026 置信度 0.80
• AcrIIA8 is a putative phage structural protein of the HTJ2 family that does not inhibit Streptococcus pyogenes Cas9.
  europepmc 2026 置信度 0.80
• Bibliometric analysis of genetically engineered bacteria in tumor therapy.
  europepmc 2026 置信度 0.80
• Application of extracellular vesicles in the CRISPR-based diagnosis and treatment: possibilities and challenges.
  europepmc 2026 置信度 0.80
• CRISPR mediated PRRS resistant pigs: biological success, welfare implications, and ethical regulatory challenges for sustainable swine production.
  europepmc 2026 置信度 0.80
• DNA repair under heat: DNA polymerase λ modulates heat stress-induced mutagenesis in plants.
  europepmc 2026 置信度 0.80
• Nanocarriers for the delivery of the CRISPR/Cas9 system.
  europepmc 2026 置信度 0.80
• The Emergence of a CRISPR-Cas Revolution in Ecology: Applications, Challenges, and an Ecologist's Overview of the Toolbox.
  europepmc 2026 置信度 0.80
• Toward an age of CRISPR delivery with non-viral biologics.
  europepmc 2026 置信度 0.80
• Advancements in CRISPR-based therapies for ocular pathologies: from disease mechanisms to intervention strategies.
  europepmc 2026 置信度 0.80
• Genetic Interruption of PD-1/PD-L1 as an Alternative Means for Immune Checkpoint Blockade in Cancer: A Review.
  europepmc 2026 置信度 0.80
• Protoplast-Based Functional Genomics and Genome Editing: Progress, Challenges and Applications.
  europepmc 2026 置信度 0.80
• CRISPR/Cas9-based programmable genome editing in chickens: concepts, applications and regulatory issues.
  europepmc 2025 置信度 0.80
• CRISPR Applications in Alzheimer's Disease: From High-Throughput Genetic Screening to Precision Editing and CNS Delivery.
  europepmc 2026 置信度 0.80
• Bibliometric-Based Analysis of Global Trends and Collaborative Networks in Plant Genetic Engineering (1994-2024).
  europepmc 2026 置信度 0.80
• Expanding the CRISPR/Cas toolkit: applications in proteomics and theranostics.
  europepmc 2025 置信度 0.80
• Resetting the epigenetic clock: cellular senescence and regenerative strategies in intervertebral disc degeneration.
  europepmc 2026 置信度 0.80
• Research note: A novel double-gene deleted vaccine against hypervirulent MDV variant generated by CRISPR/Cas9-based gene editing.
  europepmc 2026 置信度 0.80
• Optimizing phage therapy with antidefense proteins acquired from the environment.
  europepmc 2026 置信度 0.80
• Applications and Challenges of CRISPR-Cas Technology for the Detection of Antimicrobial Resistance Genes.
  europepmc 2026 置信度 0.80
• Gene Editing Strategies for Neurological and Mental Disorders: Advances in Delivery, Methodology, and Clinical Translation.
  europepmc 2026 置信度 0.80
• Functional Validation of the Melon Fom-1 Gene, Controlling Resistance to Fusarium oxysporum Races 0 and 2, by CRISPR/Cas9 Mutagenesis.
  europepmc 2026 置信度 0.80
• Engineering non-coding DNA Elements in Rice: an Elegant Approach To fine-tune Agronomical Advantageous Traits.
  europepmc 2025 置信度 0.80
• Novel genome editing approaches to manipulate apical meristem activity for crop yield.
  europepmc 2026 置信度 0.80
• Specific elimination of m.8993T>G mitochondrial haplotype in NARP cybrid cells by CRISPR-Cas9 system.
  europepmc 2026 置信度 0.80
• A practical guide for characterization of novel CRISPR-Cas systems with Pro-CRISPR factors.
  europepmc 2026 置信度 0.80
• Gene editing to enhance biotic stress tolerance in sugarcane.
  europepmc 2025 置信度 0.80
• Emerging tools in plant genome editing.
  europepmc 2025 置信度 0.80
• Dual Effect of <i>EZH2</i> Gene Editing with CRISPR/Cas9 in Lung Cancer.
  europepmc 2026 置信度 0.80
• Harnessing myostatin pleiotropy for multitrait improvement via precision gene editing.
  europepmc 2026 置信度 0.80
• Peptide-assisted lipofection enables efficient non-viral delivery of large CRISPR/Cas9 constructs for genome editing applications.
  europepmc 2025 置信度 0.80
• Application and Research Prospects of CRISPR/Cas Gene Editing Technology in Lactic Acid Bacteria.
  europepmc 2026 置信度 0.80
• Physiologically relevant 3D CRISPR screening enhances mechanistic insight into chemical toxicity compared to 2D screening.
  europepmc 2026 置信度 0.80
• Clinical outcome of an SCNT-derived <i>MSTN</i> knockout buffalo: a case study.
  europepmc 2026 置信度 0.80
• Using ngTALEN to improve genome editing efficiency on targets containing 5-methylcytosines.
  europepmc 2026 置信度 0.80
• Emerging CRISPR Approaches for Countering Immune Evasion: Insight from Recent Studies.
  europepmc 2026 置信度 0.80
• CRISPR/Cas12a: A Comprehensive Review from Structural Foundations to Applications in Nucleic Acid Precision Detection.
  europepmc 2026 置信度 0.80
• Rebuilding the degenerative disc microenvironment: mesenchymal stem cells, exosomes, and bioengineered scaffolds.
  europepmc 2026 置信度 0.80
• Targeting biofilm-driven antibiotic resistance: emerging mechanisms and next-generation therapeutic interventions.
  europepmc 2026 置信度 0.80
• Current and Emerging Therapeutic Strategies for the Treatment of Duchenne Muscular Dystrophy.
  europepmc 2026 置信度 0.80
• Feature representation for explainable CRISPR off-target prediction and base editing efficiency.
  europepmc 2026 置信度 0.80
• Viral genome editing methods and applications in the CRISPR era.
  europepmc 2026 置信度 0.80