主题图谱 / immunology

immunology

GeneTech 知识引擎共收录 125 篇相关科研实体，横跨 19 个垂直领域。数据来自 OpenAlex、arXiv、Crossref、PubMed、Europe PMC 等公开学术源，全部可溯源到原文。

年度产出趋势

代表性文献（按质量分排序，前 60 条）

• Left ventricular hypertrophy as a predictor of adverse maternal and neonatal outcomes in chronic hypertension in pregnancy: a multicenter study
  2026 · 医疗人工智能 · The impact of chronic hypertension (CHTN) combined with left ventricular hypertrophy (LVH) on adverse maternal and fetal pregnancy outcomes remains unclear. This multicenter retrospective cohort study included pregnant w…
• Left ventricular hypertrophy as a predictor of adverse maternal and neonatal outcomes in chronic hypertension in pregnancy: a multicenter study
  2026 · 医疗人工智能 · The impact of chronic hypertension (CHTN) combined with left ventricular hypertrophy (LVH) on adverse maternal and fetal pregnancy outcomes remains unclear. This multicenter retrospective cohort study included pregnant w…
• Predicting the risk of venous thromboembolism events in older adults with rheumatoid arthritis after initiating targeted disease-modifying antirheumatic drugs: a comparison of the random survival forest and regularized cox regression models
  2026 · 医疗人工智能 · To develop a random survival forest (RSF) machine learning (ML) model for predicting venous thromboembolism (VTE) risk in rheumatoid arthritis (RA) patients initiating biological (b) or targeted synthetic (ts) disease-mo…
• Predicting the risk of venous thromboembolism events in older adults with rheumatoid arthritis after initiating targeted disease-modifying antirheumatic drugs: a comparison of the random survival forest and regularized cox regression models
  2026 · 医疗人工智能 · To develop a random survival forest (RSF) machine learning (ML) model for predicting venous thromboembolism (VTE) risk in rheumatoid arthritis (RA) patients initiating biological (b) or targeted synthetic (ts) disease-mo…
• Development and internal validation of a machine learning-based disease burden index for irritable bowel syndrome: a multicentre cross-sectional study
  2026 · 医疗人工智能 · Irritable bowel syndrome (IBS) is one of the most common disorders of gut-brain interaction in gastroenterology clinics worldwide, becoming a significant public health burden. This study aims to provide an exploratory ap…
• Development and internal validation of a machine learning-based disease burden index for irritable bowel syndrome: a multicentre cross-sectional study
  2026 · 医疗人工智能 · Irritable bowel syndrome (IBS) is one of the most common disorders of gut-brain interaction in gastroenterology clinics worldwide, becoming a significant public health burden. This study aims to provide an exploratory ap…
• Variations in host-seeking behaviour and molecular insights by some newly isolated Himalayan strains of entomopathogenic nematode, <i>Heterorhabditis bacteriophora</i>
  2026 · 脑科学 · The present study investigates the variations in host recognition behaviour of five newly isolated Himalayan strains of Heterorhabditis bacteriophora towards greater wax moth, Galleria mellonella (Linnaeus, 1758; Lepidop…
• Variations in host-seeking behaviour and molecular insights by some newly isolated Himalayan strains of entomopathogenic nematode, <i>Heterorhabditis bacteriophora</i>
  2026 · 脑科学 · The present study investigates the variations in host recognition behaviour of five newly isolated Himalayan strains of Heterorhabditis bacteriophora towards greater wax moth, Galleria mellonella (Linnaeus, 1758; Lepidop…
• Beyond injury severity: monocyte-associated small extracellular vesicles distinguish respiratory-support trajectories following thoracic trauma
  2026 · 脑科学 · Abstract Thoracic trauma is a major contributor to morbidity in severely injured patients and is frequently associated with prolonged mechanical ventilation, tracheostomy, and extended intensive care unit (ICU) treatment…
• Beyond injury severity: monocyte-associated small extracellular vesicles distinguish respiratory-support trajectories following thoracic trauma
  2026 · 脑科学 · Abstract Thoracic trauma is a major contributor to morbidity in severely injured patients and is frequently associated with prolonged mechanical ventilation, tracheostomy, and extended intensive care unit (ICU) treatment…
• Clinical-pathological diagnostic concordance in inflammatory dermatoses: a single-center retrospective analysis
  2026 · 脑科学 · Inflammatory dermatoses are a heterogeneous group with overlapping clinical presentations, often requiring histopathological confirmation. The concordance between clinical impression and pathological diagnosis remains un…
• Clinical-pathological diagnostic concordance in inflammatory dermatoses: a single-center retrospective analysis
  2026 · 脑科学 · Inflammatory dermatoses are a heterogeneous group with overlapping clinical presentations, often requiring histopathological confirmation. The concordance between clinical impression and pathological diagnosis remains un…
• Clonal Hematopoiesis of Indeterminate Potential and Clonal Cytopenias of Undetermined Significance: 2026 Update on Clinical Associations and Management Recommendations.
  2026 · 碳中和与 CCUS · CONDITION OVERVIEW: Clonal hematopoiesis (CH) refers to the presence of somatic variants in hematopoietic stem and progenitor cells (HSPC) that result in expansion over time. DIAGNOSIS: CH of indeterminate potential (CHI…
• Clonal Hematopoiesis of Indeterminate Potential in Cardiovascular Disease: Gene-Specific Mechanisms and Therapeutic Implications
  2026 · 碳中和与 CCUS · -CHIP carriers, but this observation remains hypothesis-generating and requires adequately powered, CHIP-stratified outcome trials. Current translational work includes CHIP-enriched studies of inflammasome and IL-1-pathw…
• Immune Dysregulation and Cytokine Profiling in Acute Mycoplasma pneumoniae Pneumonia
  2026 · 碳中和与 CCUS · Mycoplasma pneumoniae pneumonia (MPP) is a common respiratory infection characterized by significant inflammatory responses and lung tissue injury. However, the precise immunological mechanisms and temporal dynamics of k…
• The prevalence and clinical significance of clonal monocytosis
  2026 · 碳中和与 CCUS · ABSTRACT: The terms clonal monocytosis of undetermined significance (CMUS) and clonal cytopenia and monocytosis of undetermined significance (CCMUS) were introduced by the International Consensus Classification of Myeloi…
• A state-of-the-art review on crew competence in maritime and nuclear remote operations
  2026 · 核能 · The global maritime shipping sector accounts for approximately 3% of global greenhouse gas (GHG) emissions. In response to climate concerns, the maritime industry is increasingly pursuing technological solutions to reduc…
• A state-of-the-art review on crew competence in maritime and nuclear remote operations
  2026 · 核能 · The global maritime shipping sector accounts for approximately 3% of global greenhouse gas (GHG) emissions. In response to climate concerns, the maritime industry is increasingly pursuing technological solutions to reduc…
• Design methodology of hydraulically-driven soft robotic gripper for a large and heavy object
  2026 · 机器人零部件 · This paper presents a design methodology of a hydraulically-driven soft robotic gripper for grasping a large and heavy object – approximately 10–20 kg with 20–30 cm diameter. Most existing soft grippers are pneumatically…
• Design methodology of hydraulically-driven soft robotic gripper for a large and heavy object
  2026 · 机器人零部件 · This paper presents a design methodology of a hydraulically-driven soft robotic gripper for grasping a large and heavy object – approximately 10–20 kg with 20–30 cm diameter. Most existing soft grippers are pneumatically…
• Virtual walking system with mood evaluation for individuals with severe mobility impairment: development and feasibility study
  2026 · 空间计算 · This study developed a home-based virtual walking (VW) system with integrated symptom tracking and examined its feasibility and usability in a user study with individuals with severe mobility impairment (SMI). A multidis…
• Virtual walking system with mood evaluation for individuals with severe mobility impairment: development and feasibility study
  2026 · 空间计算 · This study developed a home-based virtual walking (VW) system with integrated symptom tracking and examined its feasibility and usability in a user study with individuals with severe mobility impairment (SMI). A multidis…
• Biosynthesis of medium-chain length polyhydroxyalkanoates from pre-treated food wastewater
  2026 · 合成生物与生物制造 · Abstract Background The escalating global plastic waste crisis, coupled with the challenges of managing high-moisture food waste from industrial processing, has prompted nations worldwide to pursue sustainable alternativ…
• Biosynthesis of medium-chain length polyhydroxyalkanoates from pre-treated food wastewater
  2026 · 合成生物与生物制造 · Abstract Background The escalating global plastic waste crisis, coupled with the challenges of managing high-moisture food waste from industrial processing, has prompted nations worldwide to pursue sustainable alternativ…
• Tri-valorization of methanol in a single bioreactor: co-production of enzyme, chemical, and single-cell protein using engineered Pichia pastoris (Komagataella phaffii)
  2026 · 合成生物与生物制造 · Abstract The economic viability of methanol-based biomanufacturing, particularly with green methanol as feedstock, is often limited by the low value of single-product processes. Here, we developed an integrated co-produc…
• Tri-valorization of methanol in a single bioreactor: co-production of enzyme, chemical, and single-cell protein using engineered Pichia pastoris (Komagataella phaffii)
  2026 · 合成生物与生物制造 · Abstract The economic viability of methanol-based biomanufacturing, particularly with green methanol as feedstock, is often limited by the low value of single-product processes. Here, we developed an integrated co-produc…
• Ep. 491: The mRNA Revolution: How Scientific Grit Saved the World
  2026 · 合成生物与生物制造 · Episode summary: In this episode, Herman Poppleberry and Corn explore the incredible journey of mRNA technology, focusing on the indomitable spirit of Nobel laureate Katalin Karikó. They discuss how Karikó faced forty ye…
• Ep. 578: Beyond Nutrition: The Living Intelligence of Breast Milk
  2026 · 合成生物与生物制造 · Episode summary: In this episode, Herman and Corn dive deep into the fascinating world of infant nutrition, moving beyond simple calories to explore why breast milk remains the "gold standard" in 2026. They discuss the "…
• 44-year journey (1980–2024): scientometric insights into Sigesbeckiae herba and update on its medicinal properties and phytochemicals profile
  2026 · 中医药工具 · Abstract This study uses Scientometric analysis to review Sigesbeckiae Herba (SH) research worldwide from 1980 to 2024. Data-driven analysis identifies patterns, partnerships, and possibilities. Due to its wide profile a…
• 44-year journey (1980–2024): scientometric insights into Sigesbeckiae herba and update on its medicinal properties and phytochemicals profile
  2026 · 中医药工具 · Abstract This study uses Scientometric analysis to review Sigesbeckiae Herba (SH) research worldwide from 1980 to 2024. Data-driven analysis identifies patterns, partnerships, and possibilities. Due to its wide profile a…
• Tuina therapy for patients with chronic fatigue syndrome: a randomized controlled trial
  2026 · 中医药工具 · Abstract Background Chronic fatigue syndrome (CFS) is a complex and disabling disorder characterized by persistent fatigue and functional impairment, with limited safe and effective nonpharmacologic treatment options. Tu…
• Tuina therapy for patients with chronic fatigue syndrome: a randomized controlled trial
  2026 · 中医药工具 · Abstract Background Chronic fatigue syndrome (CFS) is a complex and disabling disorder characterized by persistent fatigue and functional impairment, with limited safe and effective nonpharmacologic treatment options. Tu…
• Ferroptosis: significance to zoonotic diseases and therapeutic prospects
  2026 · 中医药工具 · Ferroptosis is a distinct modality of programmed cell death driven by iron-dependent lipid peroxidation, exerting a pivotal regulatory influence on the infection dynamics and immune responses associated with zoonoses. Th…
• Ferroptosis: significance to zoonotic diseases and therapeutic prospects
  2026 · 中医药工具 · Ferroptosis is a distinct modality of programmed cell death driven by iron-dependent lipid peroxidation, exerting a pivotal regulatory influence on the infection dynamics and immune responses associated with zoonoses. Th…
• Xiaoqinglong Decoction Attenuates Allergic Rhinitis Comorbid with Asthma via Modulation of the ALOX15/GPX4 Axis
  2026 · 中医药工具 · Objective: Xiaoqinglong Decoction (XQLD) is a classical traditional Chinese medicine (TCM) formula for allergic rhinitis (AR) and asthma. However, its underlying therapeutic mechanisms in allergic rhinitis comorbid with …
• Xiaoqinglong Decoction Attenuates Allergic Rhinitis Comorbid with Asthma via Modulation of the ALOX15/GPX4 Axis
  2026 · 中医药工具 · Objective: Xiaoqinglong Decoction (XQLD) is a classical traditional Chinese medicine (TCM) formula for allergic rhinitis (AR) and asthma. However, its underlying therapeutic mechanisms in allergic rhinitis comorbid with …
• Unlocking the therapeutic potential of <i>Thymus serpyllum</i> L.: A systematic review of ethnopharmacology, phytochemistry and biological activity
  2026 · 中医药工具 · Thymus serpyllum L. (wild thyme) is an important panacea herb used in European and Asian countries to cure different ailments. Owing to its diverse chemical constituents concomitant with biological activities, it is wide…
• Unlocking the therapeutic potential of <i>Thymus serpyllum</i> L.: A systematic review of ethnopharmacology, phytochemistry and biological activity
  2026 · 中医药工具 · Thymus serpyllum L. (wild thyme) is an important panacea herb used in European and Asian countries to cure different ailments. Owing to its diverse chemical constituents concomitant with biological activities, it is wide…
• Real-World Effectiveness of Biologic Therapy in Allergic Bronchopulmonary Aspergillosis
  2025 · 生物计算 · BACKGROUND: Allergic bronchopulmonary aspergillosis (ABPA) is characterized by a severe hypersensitivity reaction to Aspergillus species. Current treatment relies on oral corticosteroids (OCS) and triazole antifungal the…
• Opportunities and challenges with artificial intelligence in allergy and immunology: a bibliometric study
  2025 · 医疗人工智能 · Introduction: The fields of allergy and immunology are increasingly recognizing the transformative potential of artificial intelligence (AI). Its adoption is reshaping research directions, clinical practices, and healthc…
• New tools for diagnosis of primary immunodeficiencies: from awareness to artificial intelligence
  2025 · 医疗人工智能 · Primary immune deficiencies (PI) are rare diseases associated with frequent, severe infections, inflammatory and autoimmune diseases and/or cancer. Because of the variability in presentation, undiagnosed PI patients can …
• Innate immune-inflammatory signaling milieu in myeloid leukemia and aging-associated clonal hematopoiesis pathologies.
  2025 · 碳中和与 CCUS · Age-related accumulation of somatic mutations in hematopoietic stem and progenitor cells (HSPCs), causing clonal hematopoiesis (CH), often precedes the development of hematologic malignancies. Chronic inflammation and ab…
• Therapeutic Efficacy of an Anti-P116-661 Polyclonal Antibody Against Mycoplasma pneumoniae Infection
  2025 · 碳中和与 CCUS · (MP) P116-661 protein. A polyclonal antibody against the P116-661 protein was obtained by immunizing New Zealand white rabbits, and its therapeutic effects were systematically evaluated by various experimental methods. A…
• A human oral commensal-mediated protection against Sjögren’s syndrome with maintenance of T cell immune homeostasis and improved oral microbiota
  2025 · 碳中和与 CCUS · Abstract Sjögren’s syndrome (SS) is a prevalent systemic autoimmune disease with substantial impacts on women’s health worldwide. Although oral Haemophilus parainfluenzae is reduced in SS, its significance remains unclea…
• Immune evasion in cancer: mechanisms and cutting-edge therapeutic approaches
  2025 · 边缘智能 · Immune evasion represents a significant challenge in oncology. It allows tumors to evade immune surveillance and destruction, thereby complicating therapeutic interventions and contributing to suboptimal patient outcomes…
• Identification of serum tRNA-derived small RNAs biosignature for diagnosis of tuberculosis
  2025 · 地外科学 · The tRNA-derived small RNAs (tsRNAs) are a new class of non coding RNAs, which are stable in body fluids and can be used as potential biomarkers for disease diagnosis. However, the exact value of tsRNAs in the diagnosis …
• Identification of serum tRNA-derived small RNAs biosignature for diagnosis of tuberculosis
  2025 · 地外科学 · The tRNA-derived small RNAs (tsRNAs) are a new class of non coding RNAs, which are stable in body fluids and can be used as potential biomarkers for disease diagnosis. However, the exact value of tsRNAs in the diagnosis …
• Technical Report on Mirror Bacteria: Feasibility and Risks
  2025 · 合成生物与生物制造 · This report describes the technical feasibility of creating mirror bacteria and the potentially serious and wide-ranging risks that they could pose to humans, other animals, plants, and the environment. It accompanies th…
• Efficacy of Shenkang Injection combined with renin-angiotensin-aldosterone system blockers in diabetic nephropathy: a systematic review and meta-analysis of randomized controlled trials
  2025 · 中医药工具 · Shenkang injection (SKI), a Traditional Chinese Medicine formulation, is widely used in China for diabetic nephropathy (DN). This systematic review and meta-analysis aimed to evaluate the efficacy and safety of SKI combi…
• Efficacy of Shenkang Injection combined with renin-angiotensin-aldosterone system blockers in diabetic nephropathy: a systematic review and meta-analysis of randomized controlled trials
  2025 · 中医药工具 · Shenkang injection (SKI), a Traditional Chinese Medicine formulation, is widely used in China for diabetic nephropathy (DN). This systematic review and meta-analysis aimed to evaluate the efficacy and safety of SKI combi…
• Progress of Pretreatment and Analysis Methods for Brucine and Strychnine: An Update Since 2013
  2025 · 中医药工具 · Brucine and strychnine, primary bioactive constituents in traditional Chinese medicine, are extensively utilized in healthcare products due to their pharmacological and biochemical properties, including the enhancement o…
• Progress of Pretreatment and Analysis Methods for Brucine and Strychnine: An Update Since 2013
  2025 · 中医药工具 · Brucine and strychnine, primary bioactive constituents in traditional Chinese medicine, are extensively utilized in healthcare products due to their pharmacological and biochemical properties, including the enhancement o…
• Intestinal mucosal barrier repair and immune regulation with an AI-developed gut-restricted PHD inhibitor
  2024 · AI 安全与对齐 · Hypoxia-inducible factor prolyl hydroxylase (PHD) inhibitors have been approved for treating renal anemia yet have failed clinical testing for inflammatory bowel disease because of a lack of efficacy. Here we used a mult…
• Immunoglobulin G N-glycan markers of accelerated biological aging during chronic HIV infection
  2024 · 生物计算 · People living with HIV (PLWH) experience increased vulnerability to premature aging and inflammation-associated comorbidities, even when HIV replication is suppressed by antiretroviral therapy (ART). However, the factors…
• hucMSC-Ex alleviates inflammatory bowel disease in mice by enhancing M2-type macrophage polarization via the METTL3-Slc37a2-YTHDF1 axis
  2024 · 碳中和与 CCUS · Human umbilical cord mesenchymal stem cell-derived exosomes (hucMSC-Ex) have emerged as a new treatment strategy for inflammatory bowel disease (IBD) due to their immunoregulatory function. N6-methyladenosine (m6A) plays…
• Additional file 2 of Neutrophils cultured ex vivo from CD34+ stem cells are immature and genetically tractable
  2024 · 基因技术工具 · Supplementary material 2 : Fig. S1 Additional characterisation of cultured neutrophils. A: Schematic outlining culture procedure (top) or acquisition of native neutrophils. Figure generated in Biorender. B: Representativ…
• Additional file 2 of Neutrophils cultured ex vivo from CD34+ stem cells are immature and genetically tractable
  2024 · 基因技术工具 · Supplementary material 2 : Fig. S1 Additional characterisation of cultured neutrophils. A: Schematic outlining culture procedure (top) or acquisition of native neutrophils. Figure generated in Biorender. B: Representativ…
• Human IgG Fc-engineering for enhanced plasma half-life, mucosal distribution and killing of cancer cells and bacteria
  2024 · 生命科学 · Monoclonal IgG antibodies constitute the fastest growing class of therapeutics. Thus, there is an intense interest to design more potent antibody formats, where long plasma half-life is a commercially competitive differe…
• Recent advancements in traditional Chinese medicine for COVID-19 with comorbidities across various systems: a scoping review
  2024 · 中医药工具 · Abstract Background Traditional Chinese medicine (TCM) has developed a rich theoretical system and practical experience in fighting to infectious diseases over the past thousands of years, and has played an important rol…
• Recent advancements in traditional Chinese medicine for COVID-19 with comorbidities across various systems: a scoping review
  2024 · 中医药工具 · Abstract Background Traditional Chinese medicine (TCM) has developed a rich theoretical system and practical experience in fighting to infectious diseases over the past thousands of years, and has played an important rol…

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