主题图谱 / bioinformatics

bioinformatics

GeneTech 知识引擎共收录 156 篇相关科研实体，横跨 18 个垂直领域。数据来自 OpenAlex、arXiv、Crossref、PubMed、Europe PMC 等公开学术源，全部可溯源到原文。

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代表性文献（按质量分排序，前 60 条）

• OpenScientist: Supplementary Case Study Data
  2026 · AI Agent 生态 · Supplementary data for "OpenScientist: evaluating an open agentic AI co-scientist to accelerate biomedical discovery." This dataset contains research logs, knowledge states, provenance files, and generated figures for se…
• OpenScientist: Supplementary Case Study Data
  2026 · AI Agent 生态 · Supplementary data for "OpenScientist: evaluating an open agentic AI co-scientist to accelerate biomedical discovery." This dataset contains research logs, knowledge states, provenance files, and generated figures for se…
• VU Bioinformatics/NGS Suite: MicroRNA–Target Gene Mapping Bar Plot
  2026 · 生物计算 · VU Bioinformatics/NGS Suite: MicroRNA–Target Gene Mapping Bar Plot What is this work about? This work is part of a research project investigating the role of microRNAs (miRNAs) in regulating gene expression relevant to d…
• Organ cross-talk: molecular mechanisms, biological functions, and therapeutic interventions for diseases
  2026 · 生物计算 · Organ cross-talk, also known as the organ axis or organ interaction network, plays a vital role in maintaining physiological homeostasis and responding to environmental stimuli. This review comprehensively integrates cut…
• Biologics for bone regeneration: advances in cell, protein, gene, and mRNA therapies
  2026 · 生物计算 · Bone fractures represent a significant global healthcare burden. Although fractures typically heal on their own, some fail to regenerate properly, leading to nonunion, a condition that causes prolonged disability, morbid…
• Clonal Hematopoiesis of Indeterminate Potential in Cardiovascular Disease: Gene-Specific Mechanisms and Therapeutic Implications
  2026 · 碳中和与 CCUS · -CHIP carriers, but this observation remains hypothesis-generating and requires adequately powered, CHIP-stratified outcome trials. Current translational work includes CHIP-enriched studies of inflammasome and IL-1-pathw…
• Integrating Molecular Pathogenesis and Host Response into a Digital Twin Framework for Predicting Therapeutic Outcomes in <i>Balamuthia mandrillaris</i> Encephalitis.
  2026 · 数字孪生 · High Resolution Image Download MS PowerPoint Slide Balamuthia mandrillaris is a free-living amoeba that causes granulomatous amoebic encephalitis, a rare but devastating central nervous system infection with mortality ex…
• OpenScientist: Supplementary Case Study Data
  2026 · 基因技术工具 · Supplementary data for "OpenScientist: evaluating an open agentic AI co-scientist to accelerate biomedical discovery." This dataset contains research logs, knowledge states, provenance files, and generated figures for se…
• OpenScientist: Supplementary Case Study Data
  2026 · 基因技术工具 · Supplementary data for "OpenScientist: evaluating an open agentic AI co-scientist to accelerate biomedical discovery." This dataset contains research logs, knowledge states, provenance files, and generated figures for se…
• Nextflow for the life sciences (NF4LS) Trainers materials
  2026 · 生命科学 · This training material is designed to help other Trainers re-run and adapt the 'Nextflow for the life sciences' workshop for their own learners. It includes ready-to-use materials and guidance for delivering a two-part w…
• PromptBio: A Multi-Agent AI Platform for Bioinformatics Data Analysis
  2025 · AI 安全与对齐 · Abstract PromptBio is a modular AI platform for scalable, reproducible, and user-adaptable bioinformatics analysis, powered by generative AI and natural language interaction. It supports three complementary modes of anal…
• On the biologically relevant chemical space: BioReCS
  2025 · 生物计算 · The "chemical space" (CS), "chemical compound space," or "chemical universe" terms are frequently used in drug discovery and other areas, including chemical synthesis, catalysis, materials science, food chemistry, and ag…
• Multi-organ metabolome biological age implicates cardiometabolic conditions and mortality risk
  2025 · 生物计算 · Multi-organ biological aging clocks across different organ systems have been shown to predict human disease and mortality. Here, we extend this multi-organ framework to plasma metabolomics, developing five organ-specific…
• Multi-omics architecture of childhood obesity and metabolic dysfunction uncovers biological pathways and prenatal determinants
  2025 · 生物计算 · Childhood obesity poses a significant public health challenge, yet the molecular intricacies underlying its pathobiology remain elusive. Leveraging extensive multi-omics profiling (methylome, miRNome, transcriptome, prot…
• Obesity and Its Comorbidities: Current Treatment Options, Emerging Biological Mechanisms, Future Perspectives and Challenges
  2025 · 生物计算 · Obesity is a chronic, multifactorial disease and a major global public health challenge. Defined by excessive fat accumulation, obesity significantly increases the risk of numerous diseases, including type 2 diabetes mel…
• Role of Generative Artificial Intelligence in Personalized Medicine: A Systematic Review
  2025 · 医疗人工智能 · Precision medicine presents challenges in data collection, cost, and privacy as it tailors treatments to each patient's unique genetic and clinical profile. With its ability to produce realistic and confidential patient …
• Computer-Aided Application in Medicine and Biomedicine
  2025 · 仿生智能 · Abstract Computer-aided applications in medicine and biomedicine drive the advancement of diagnostics, treatment, and research by leveraging data processing, analysis, and innovation. Computer technologies are used in me…
• Oxidative Stress and Its Role in the Emergence and Progression of Myelodysplastic Syndromes: Insights from Proteomic Analysis and Other Methodologies
  2025 · 碳中和与 CCUS · Myelodysplastic syndromes (MDS) belong to a category of malignant stem-cell and myeloid disorders that deteriorate the function of the hematopoietic system exacerbated by the omnipresent anemia that characterizes myelody…
• Early life gut microbiome and its impact on childhood health and chronic conditions
  2025 · 生命科学 · The development of the gut microbiome is crucial to human health, particularly during the first three years of life. Given its role in immune development, disturbances in the establishment process of the gut microbiome m…
• Empowering biomedical discovery with AI agents
  2024 · AI Agent 生态 · We envision "AI scientists" as systems capable of skeptical learning and reasoning that empower biomedical research through collaborative agents that integrate AI models and biomedical tools with experimental platforms. …
• Integrating Omics Data and AI for Cancer Diagnosis and Prognosis
  2024 · AI 驱动科学发现 · Cancer is one of the leading causes of death, making timely diagnosis and prognosis very important. Utilization of AI (artificial intelligence) enables providers to organize and process patient data in a way that can lea…
• Quantum computing in bioinformatics: a systematic review mapping
  2024 · 生物计算 · The field of quantum computing (QC) is expanding, with efforts being made to apply it to areas previously covered by classical algorithms and methods. Bioinformatics is one such domain that is developing in terms of QC. …
• Large language model to multimodal large language model: A journey to shape the biological macromolecules to biological sciences and medicine
  2024 · 生物计算 · After ChatGPT was released, large language models (LLMs) became more popular. Academicians use ChatGPT or LLM models for different purposes, and the use of ChatGPT or LLM is increasing from medical science to diversified…
• InterPro: the protein sequence classification resource in 2025
  2024 · 生物计算 · InterPro (https://www.ebi.ac.uk/interpro) is a freely accessible resource for the classification of protein sequences into families. It integrates predictive models, known as signatures, from multiple member databases to…
• Epigenetic Clocks: Beyond Biological Age, Using the Past to Predict the Present and Future
  2024 · 生物计算 · Predicting health trajectories and accurately measuring aging processes across the human lifespan remain profound scientific challenges. Assessing the effectiveness and impact of interventions targeting aging is even mor…
• Association between biological aging and diabetic retinopathy
  2024 · 生物计算 · The impact of aging on diabetic retinopathy (DR) remains underestimated. The current study aimed to investigate the association between biological aging and DR, in contrast to chronological age (CA). Using the National H…
• Artificial intelligence-based MRI radiomics and radiogenomics in glioma
  2024 · 医疗人工智能 · The specific genetic subtypes that gliomas exhibit result in variable clinical courses and the need to involve multidisciplinary teams of neurologists, epileptologists, neurooncologists and neurosurgeons. Currently, the …
• Life at the borderlands: microbiomes of interfaces critical to One Health
  2024 · 仿生智能 · Microbiomes are foundational components of the environment that provide essential services relating to food security, carbon sequestration, human health, and the overall well-being of ecosystems. Microbiota exert their e…
• A Multidisciplinary Hyper-Modeling Scheme in Personalized In Silico Oncology: Coupling Cell Kinetics With Metabolism, Signaling Networks and Biomechanics As Plug-In Component Models of a Cancer Digital Twin
  2024 · 数字孪生 · The massive amount of human biological, imaging and clinical data produced by multiple and diverse sources, necessitates integrative modeling approaches able to summarize all this information into answers to specific cli…
• 2024 European Thyroid Association Guidelines on diagnosis and management of genetic disorders of thyroid hormone transport, metabolism and action
  2024 · 生命科学 · Impaired sensitivity to thyroid hormones encompasses disorders with defective transport of hormones into cells, reduced hormone metabolism, and resistance to hormone action. Mediated by heritable single-gene defects, the…
• Quantum computing in bioinformatics: a systematic review mapping.
  2024 · 量子计算 · The field of quantum computing (QC) is expanding, with efforts being made to apply it to areas previously covered by classical algorithms and methods. Bioinformatics is one such domain that is developing in terms of QC. …
• DrugBank 6.0: the DrugBank Knowledgebase for 2024
  2023 · 生物计算 · First released in 2006, DrugBank (https://go.drugbank.com) has grown to become the 'gold standard' knowledge resource for drug, drug-target and related pharmaceutical information. DrugBank is widely used across many dive…
• Gene networks for use in metabolomic data analysis of blood plasma from patients with postoperative delirium
  2023 · 碳中和与 CCUS · Postoperative delirium (POD) is considered one of the most severe complications, resulting in impaired cognitive function, extended hospitalization, and higher treatment costs. The challenge of early POD diagnosis become…
• Series I: A Comprehensive Collection: The Jian-Da Protocol and Evolutionary Ontology (A Closed-Loop Series of 36 Papers) / 見大協議與演化本體論全集 (閉環體系論文共36篇)
  2026 · AI 安全与对齐 · This project presents the comprehensive research papers authored by independent researcher Shun-Ching Lee (李順晴) from February to May 2026. Entitled "The Jian-Da Protocol and Evolutionary Ontology," this series establishe…
• Determinants of clonal-evolutionary mode at recurrence in diffuse glioma: a scoping review and protocol
  2026 · AI 驱动科学发现 · Determinants of clonal-evolutionary mode at recurrence in diffuse glioma: a scoping review — protocol (v1.0, 17 Aug 2026) Author/guarantor: Alexandru C. Stan, MD, PhD (ORCID 0000-0002-7463-0393), independent researcher. …
• isabelschoeps-thiel/Bioinformatics-Oxford-University-Press: Briefings in Bioinformatics, Oxford University Press by Isabel Schöps geb. Thiel
  2026 · AI 驱动科学发现 · Briefings in Bioinformatics, Oxford University Press, interdisziplinär als Teil der SIA Security Intelligence Artefact Research, The Yellow Whitepaper Series Release: oxford-1.2 Autorin: Frau Isabel Schöps, geborene Thie…
• Machine Learning in Birth Weight Prediction: A Systematic Review of Low and High Birth Weight Predictive Models
  2026 · AI 驱动科学发现 · This systematic review evaluates the reported predictive performance of machine learning (ML) models that use low birth weight (LBW) or high birth weight (HBW, including macrosomia and large-for-gestational-age) as the d…
• ProteinFP: A Multi-Module Pipeline for Protein Function Prediction and Drug Discovery
  2026 · AI 驱动科学发现 · ProteinFP is a comprehensive, modular Python pipeline for automated protein function prediction and computational drug candidate design. Given a UniProt accession, it integrates 21+ analysis modules spanning structural b…
• ProteinFP: A Multi-Module Pipeline for Protein Function Prediction and Drug Discovery
  2026 · AI 驱动科学发现 · ProteinFP is a comprehensive, modular Python pipeline for automated protein function prediction and computational drug candidate design. Given a UniProt accession, it integrates 21+ analysis modules spanning structural b…
• isabelschoeps-thiel/Bioinformatics-Oxford-University-Press: Briefings in Bioinformatics, Oxford University Press by Isabel Schöps geb. Thiel
  2026 · 仿生智能 · Briefings in Bioinformatics, Oxford University Press, interdisziplinär als Teil der SIA Security Intelligence Artefact Research, The Yellow Whitepaper Series Release: oxford-1.2 Autorin: Frau Isabel Schöps, geborene Thie…
• The diffuse-glioma interventional-trial landscape - molecular-era representation, global access, discontinuation, and eligibility restrictiveness: a scoping review and evidence-gap map.
  2026 · 脑科学 · Scoping-review protocol (JBI methodology; PRISMA-ScR reporting). Review type. Scoping review (Arksey & O'Malley; Levac et al.; JBI 2020), reported per PRISMA-ScR. Descriptive charting and evidence-mapping only - no h…
• Computational Biology vs Bioinformatics: A 2025 Guide for Biomedical Researchers
  2026 · 基因技术工具 · This comprehensive guide for biomedical researchers and drug development professionals delineates the distinct yet complementary roles of bioinformatics and computational biology. Bioinformatics is defined as the field f…
• Computational Biology vs Bioinformatics: A 2025 Guide for Biomedical Researchers
  2026 · 基因技术工具 · This comprehensive guide for biomedical researchers and drug development professionals delineates the distinct yet complementary roles of bioinformatics and computational biology. Bioinformatics is defined as the field f…
• PIASO tutorial and processed single-cell omics datasets
  2026 · 基因技术工具 · This record contains a collection of single-cell omics datasets in AnnData HDF5 (.h5ad), cytome (.cytome) and other formats associated with PIASO (Precise Integrative Analysis of Single-cell Omics), a Python toolkit for …
• PIASO tutorial and processed single-cell omics datasets
  2026 · 基因技术工具 · This record contains a collection of single-cell omics datasets in AnnData HDF5 (.h5ad) format and other formats associated with PIASO (Precise Integrative Analysis of Single-cell Omics), a Python toolkit for single-cell…
• Multi-Omics Characterization of Abdominal Aortic Aneurysm via 3D Image-Derived Phenotypes
  2026 · 基因技术工具 · Abdominal aortic aneurysm (AAA) is a complex, life-threatening disease marked by an enlargement of the abdominal aorta. Traditional diagnosis relies on measuring abdominal aortic diameter (AAD) from imaging data collecte…
• Multi-Omics Characterization of Abdominal Aortic Aneurysm via 3D Image-Derived Phenotypes
  2026 · 基因技术工具 · Abdominal aortic aneurysm (AAA) is a complex, life-threatening disease marked by an enlargement of the abdominal aorta. Traditional diagnosis relies on measuring abdominal aortic diameter (AAD) from imaging data collecte…
• The diffuse-glioma interventional-trial landscape - molecular-era representation, global access, discontinuation, and eligibility restrictiveness: a scoping review and evidence-gap map.
  2026 · 基因技术工具 · Scoping-review protocol (JBI methodology; PRISMA-ScR reporting). Review type. Scoping review (Arksey & O'Malley; Levac et al.; JBI 2020), reported per PRISMA-ScR. Descriptive charting and evidence-mapping only - no h…
• Human Disease-Protein Mapping Dataset (HDPM-Dataset) from UniProt
  2026 · 基因技术工具 · This dataset provides a structured mapping between human pathologies and their associated proteins, extracted from the UniProt bioinformatics portal. The collection comprises a randomly selected sample of 2,000 human dis…
• Human Disease-Protein Mapping Dataset (HDPM-Dataset) from UniProt
  2026 · 基因技术工具 · This dataset provides a structured mapping between human pathologies and their associated proteins, extracted from the UniProt bioinformatics portal. The collection comprises a randomly selected sample of 2,000 human dis…
• PIASO tutorial and processed single-cell omics datasets
  2026 · 基因技术工具 · This record contains a collection of single-cell omics datasets in AnnData HDF5 (.h5ad), cytome (.cytome) and other formats associated with PIASO (Precise Integrative Analysis of Single-cell Omics), a Python toolkit for …
• Bioinformatics-CLI-Toolkit
  2026 · 基因技术工具 · First citable release of the Bioinformatics CLI Toolkit — a collection of command-line tools for genome inspection, comparative genomics, and regulatory motif discovery built around GenBank-format assemblies. The toolkit…
• Bioinformatics-CLI-Toolkit
  2026 · 基因技术工具 · First citable release of the Bioinformatics CLI Toolkit — a collection of command-line tools for genome inspection, comparative genomics, and regulatory motif discovery built around GenBank-format assemblies. The toolkit…
• Determinants of clonal-evolutionary mode at recurrence in diffuse glioma: a scoping review and protocol
  2026 · 基因技术工具 · Determinants of clonal-evolutionary mode at recurrence in diffuse glioma: a scoping review — protocol (v1.0, 17 Aug 2026) Author/guarantor: Alexandru C. Stan, MD, PhD (ORCID 0000-0002-7463-0393), independent researcher. …
• The diffuse-glioma interventional-trial landscape - molecular-era representation, global access, discontinuation, and eligibility restrictiveness: a scoping review and evidence-gap map.
  2026 · 生命科学 · Scoping-review protocol (JBI methodology; PRISMA-ScR reporting). Review type. Scoping review (Arksey & O'Malley; Levac et al.; JBI 2020), reported per PRISMA-ScR. Descriptive charting and evidence-mapping only - no h…
• Machine Learning in Birth Weight Prediction: A Systematic Review of Low and High Birth Weight Predictive Models
  2026 · 生命科学 · This systematic review evaluates the reported predictive performance of machine learning (ML) models that use low birth weight (LBW) or high birth weight (HBW, including macrosomia and large-for-gestational-age) as the d…
• Determinants of clonal-evolutionary mode at recurrence in diffuse glioma: a scoping review and protocol
  2026 · 生命科学 · Determinants of clonal-evolutionary mode at recurrence in diffuse glioma: a scoping review — protocol (v1.0, 17 Aug 2026) Author/guarantor: Alexandru C. Stan, MD, PhD (ORCID 0000-0002-7463-0393), independent researcher. …
• Cyclic mechanical stretch and cardiac fibroblast activation in vitro: a systematic review and exploratory meta-analysis
  2026 · 生命科学 · Title Cyclic mechanical stretch and cardiac fibroblast activation in vitro: a systematic review and exploratory meta-analysis Registration summary This registration describes a prospective protocol for an independent sys…
• Computational Biology vs Bioinformatics: A 2025 Guide for Biomedical Researchers
  2026 · 隐私计算与数据要素 · This comprehensive guide for biomedical researchers and drug development professionals delineates the distinct yet complementary roles of bioinformatics and computational biology. Bioinformatics is defined as the field f…
• Computational Biology vs Bioinformatics: A 2025 Guide for Biomedical Researchers
  2026 · 隐私计算与数据要素 · This comprehensive guide for biomedical researchers and drug development professionals delineates the distinct yet complementary roles of bioinformatics and computational biology. Bioinformatics is defined as the field f…

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