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synthetic biology

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• Cellulose-based sensors for decentralized monitoring in precision agriculture.
  2026 · 智慧农业 · Abstract Modern agriculture requires rapid, affordable tools to monitor crops and soils directly in the field. Cellulose, the structural polymer of plants, is emerging as a versatile foundation for lightweight, biodegrad…
• Precision fermentation and recombinant proteins as enabling technologies for scalable cellular agriculture.
  2026 · 智慧农业 · Cellular agriculture has emerged as a promising strategy for producing animal-derived food components through controlled biological processes while reducing the environmental and ethical burdens associated with conventio…
• AI-Assisted Spatial Metabolic Engineering in Plants: Integrating Flux Design, Spatial Omics, and Synthetic Biology.
  2026 · AI 驱动科学发现 · Background: Plant synthetic biology reprograms metabolic networks for the sustainable production of high-value compounds. Recent computational advances incorporate machine learning to accelerate the design-build-test-lea…
• Toward Rational Design of Precision-Fermented Milk Proteins: Integrating Cross-Species Selection, Post-Translational Modification, and AI Optimization.
  2026 · AI 驱动科学发现 · Milk proteins deliver nutritional, functional, and bioactive properties that alternative protein sources cannot adequately replicate, yet conventional livestock-based production faces compounding constraints of scalabili…
• Uncovering Complicated Plant Biological Networks through the Assistance of Artificial Intelligence Tools
  2026 · 智慧农业 · Plant biological networks, comprising gene regulatory, protein–protein interaction (PPI), and metabolic pathways, are intricate systems fundamental to understanding plant development and physiology. The advent of artific…
• Stoichiometry dependent properties of cerium hydride: An active learning developed interatomic potential study
  2026 · AI 驱动科学发现 · Cerium hydride has a variety of interesting properties, including a known lattice contraction and densification with increasing hydrogen content. However, precise stoichiometric control is not experimentally straightforw…
• A Model‐Based Deep‐Learning Approach to Reconstructing the Highly Articulated Flight Kinematics of Bats
  2025 · AI 驱动科学发现 · ABSTRACT Bats are capable of highly dexterous flight maneuvers that rely heavily on highly articulated hand skeletons and malleable wing membranes. To understand the underlying mechanisms, large amounts of detailed data …
• Synthetic Aptamer Mechanoreceptors Enable Cell-Specific Force Sensing and Temporal Control via DNA Circuits
  2025 · 生物计算 · Abstract Cells interpret mechanical cues from their microenvironment with spatiotemporal precision to guide adaptive behaviors. However, engineering synthetic mechanosensing systems with both cell-specificity and program…
• Biomimetic Closed-Loop Control of a Novel Soft Gastric Simulator Toward Emulating Antral Contraction Waves
  2024 · 智慧农业 · Soft gastric simulators are in vitro biomimetic modules that can reproduce the antral contraction waves (ACWs). Along with providing information concerning stomach contents, stomach simulators enable experts to evaluate …
• DescribePROT Database of Residue-Level Protein Structure and Function Annotations
  2024 · AI 驱动科学发现 · DescribePROT is a freely available online database of structural and functional descriptors of proteins at the amino acid level. It provides access to 13 diverse descriptors that include sequence conservation, putative s…
• A survey of generative AI for de novo drug design: new frontiers in molecule and protein generation
  2024 · AI 驱动科学发现 · Artificial intelligence (AI)-driven methods can vastly improve the historically costly drug design process, with various generative models already in widespread use. Generative models for de novo drug design, in particul…
• Biomanufacturing and bioprocessing of lunar regolith
  2024 · 地外矿物 · Microbial biomanufacturing is important to accelerate lunar construction because it can leverage lunar material and waste streams as feedstocks to create a circular production system. In-space bio-mining and biomanufactu…
• Synthetic dosage-compensating miRNA circuits for quantitative gene therapy
  2024 · 生物计算 · A longstanding challenge in gene therapy is expressing a dosage-sensitive gene within a tight therapeutic window. For example, loss of MECP2 function causes Rett syndrome, while its duplication causes MECP2 duplication s…
• Exabiome: Advancing Microbial Science through Exascale Computing
  2024 · 生物计算 · The Exabiome project seeks to improve the understanding of microbiomes through the development of methods for accelerating metagenomic science using exascale computing. This article gives an overview of scientific impact…
• Microbial Growth
  2024 · 生物计算 · This chapter discusses microbial growth, and looks particularly at how microorganisms grow in liquid culture. The usefulness of microbes in biotechnology applications originates from their ability to convert low-cost sub…
• Microbial Bio-Production
  2024 · 生物计算 · This chapter covers the extent of microbial bio-production. It examines the role microorganisms play in bio-production and the production of pharmaceuticals by microorganisms. Microbial products have a varied chemical na…
• Microbial Biotechnology and Agriculture
  2024 · 生物计算 · This chapter examines the important role microbes play in the future of sustainable agriculture. It looks into microbes as biological control agents and the use of bacteria as genetic tools and microbial inoculants. The …
• Farmer-led on-farm experimentation enhanced with digital agronomy
  2023 · 智慧农业 · Agriculture puts pressure on ecosystems, and practices need to evolve towards a more sustainable way of producing food. Farmers are changing their practices by conducting on-farm experimentation with their own objectives…
• A Flexible Escape Skin Bioinspired by the Defensive Behavior of Shedding Scales
  2023 · 智慧农业 · Artificial skins with functions such as sensing, variable stiffness, actuation, self-healing, display, adhesion, and camouflage have been developed and widely used, but artificial skins with escape function are still a r…
• Applications of synthetic biology in medical and pharmaceutical fields
  2023 · 生物计算 · Synthetic biology aims to design or assemble existing bioparts or bio-components for useful bioproperties. During the past decades, progresses have been made to build delicate biocircuits, standardized biological buildin…
• Code for the RiskPath pilot: auditable risk-path routing in a synthetic public health emergency
  2026 · AI Agent 生态 · This software archive contains the experiment implementation and plotting code for the RiskPath pilot study on auditable risk-path routing for multi-agent coordination in a synthetic public health emergency. The archive …
• Code for the RiskPath pilot: auditable risk-path routing in a synthetic public health emergency
  2026 · AI Agent 生态 · This software archive contains the experiment implementation and plotting code for the RiskPath pilot study on auditable risk-path routing for multi-agent coordination in a synthetic public health emergency. The archive …
• Revid AI Coupon Code 20SAVE – Real Value | 2026
  2026 · AI 安全与对齐 · Revid AI Coupon Code 20SAVE -Real Value | 2026Revid AI is an advanced AI-powered video creation platform designed for creators, marketers, entrepreneurs, and businesses who want to produce high-quality videos faster and …
• FROM EMPIRICAL HERBAL MEDICINE TO PREDICTIVE THERAPEUTICS: THE ROLE OF AI AND MULTI-OMICS
  2026 · AI 驱动科学发现 · Purpose: Medicinal plants are the richest source of structurally diverse biologically active compounds. Herbal leads discovery can also be accelerated using artificial intelligence and multi omics technologies. This revi…
• FROM EMPIRICAL HERBAL MEDICINE TO PREDICTIVE THERAPEUTICS: THE ROLE OF AI AND MULTI-OMICS
  2026 · AI 驱动科学发现 · Purpose: Medicinal plants are the richest source of structurally diverse biologically active compounds. Herbal leads discovery can also be accelerated using artificial intelligence and multi omics technologies. This revi…
• THE INNER WORKINGS OF RIPENING: PHYSIOLOGY, BIOCHEMISTRY, AND MOLECULAR INSIGHTs
  2025 · 智慧农业 · Abstract : Fruit ripening is a complex, finely regulated developmental process that transitions fruit from growth to senescence, resulting in enhanced sensory and nutritional attributes. These changes are orchestrated th…
• THE INNER WORKINGS OF RIPENING: PHYSIOLOGY, BIOCHEMISTRY, AND MOLECULAR INSIGHTs
  2025 · 智慧农业 · Abstract : Fruit ripening is a complex, finely regulated developmental process that transitions fruit from growth to senescence, resulting in enhanced sensory and nutritional attributes. These changes are orchestrated th…
• Evolution and AI: Bringing New Chemistry to Life
  2025 · AI 驱动科学发现 · Evolution is the most powerful design process ever invented. A simple algorithm of mutation and natural selection has given rise to all the diversity of life, including the stunningly beautiful chemistry that is constant…
• DNA Algorithmic Self-Assembly
  2025 · 生物计算 · Abstract Since Seeman proposed using DNA as a nanomaterial, DNA Tile and DNA origami technologies have been successively proposed, and DNA has realized the programmable assembly from two-dimensional patterns to three-dim…
• Bisphenol a polycarbonate remediation: A molecular docking approach to understanding microbial enzyme activity
  2025 · 生物计算 · Bisphenol A (BPA) is an organic synthetic chemical used to make polycarbonate and epoxy resins. As plastic waste breaks down, it may leak out and contaminate nearby water and soil sources. BPA has been connected to detri…
• Synthetic biology for space exploration.
  2025 · 地外矿物 · Human space exploration faces different challenges. Topics like Bioregenerative Life Support Systems, In Situ Resource Utilization, and radiation protection, still require for more suitable solutions to be applied in lon…
• PRECISION AGRICULTURE: ENHANCING RICE LEAF DISEASE CLASSIFICATION AND PREDICTION WITH A CUSTOM CONVOLUTIONAL NEURAL NETWORKS
  2026 · 智慧农业 · IIPSeries aims to provide platform for Researchers/Scientists/Students etc. across the world, to present and publish their research papers on recent advances in the different fields of science and engineering by conducti…
• Field-programmable biological circuits and configurable (bio)logic blocks for distributed biological computing.
  2020 · 生物计算 · Synthetic biology applications often require engineered computing structures, which can be programmed to process the information in a given way. However, programming of these structures usually requires significant amoun…
• Engineering <scp>DNA</scp> Switches for <scp>DNA</scp> Computing Applications
  2021 · 生物计算 · The deoxyribonucleic acid (DNA) is a convenient molecule for the rational design of molecular switches and is ideally suitable for the development of molecular computing systems. Throughout this chapter, we discuss how o…
• Nanopore Decoding for <scp>DNA</scp> Computing
  2021 · 生物计算 · This chapter introduces recent developments in nanopore decoding methods for DNA computing, its potential application, and future challenges. In conventional DNA computing methods for logic gate operations, the outputs a…
• Wearable materials with embedded synthetic biology sensors for biomolecule detection
  2021 · 生物计算 · Integrating synthetic biology into wearables could expand opportunities for noninvasive monitoring of physiological status, disease states and exposure to pathogens or toxins. However, the operation of synthetic circuits…
• Designing Biological Circuits: Synthetic Biology Within the Operon Model and Beyond
  2021 · 生物计算 · In 1961, Jacob and Monod proposed the operon model of gene regulation. At the model's core was the modular assembly of regulators, operators, and structural genes. To illustrate the composability of these elements, Jacob…
• Synthetic neural-like computing in microbial consortia for pattern recognition
  2020 · 生物计算 · Abstract Complex biological systems in nature comprise of cells that act collectively to solve sophisticated tasks. Synthetic biological systems, in contrast, are designed for specific tasks, largely following computatio…
• AI Methods and Agent Architectures
  2024 · AI Agent 生态 · This chapter provides an overview of AI techniques and history to aid students who are not familiar with AI to understand the basis for today’s AI techniques. This chapter is not intended to provide an overview of all AI…
• AI-Powered Synthetic Personas
  2024 · AI 安全与对齐 · Public relations (PR) revolves around cultivating positive connections between organizations and their audiences. With the emergence of artificial intelligence (AI), synthetic personas – virtual representations of real i…
• Human scRNA-seq Alignment Pipeline Version 1.0 v1
  2024 · AI 安全与对齐 · The Morrisey and Basil Labs at the University of Pennsylvania use a specific protocol for scRNA-seq (single-cell RNA sequencing) alignment that involves the STARsolo tool (version 2.9.7a) to generate outputs comparable t…
• Microbial Revolt: Redefining biolab tools and practices for more-than-human care ecologies
  2024 · 生物计算 · Recent work in HCI has called for deeper ethical considerations when engaging with more-than-human organisms in design. In this paper, we introduce Microbial Revolt, a provocative method to support reflection on the pers…
• Prediction of transmembrane protein topology
  2023 · AI 驱动科学发现 · Abstract Membrane proteins fulfil many critical cellular functions, and make up a large fraction of all proteins. In fact, it has recently been estimated that as many as 35–-40% of all yeast genes may code for integral m…
• Multiple-Valued DNA Computing
  2023 · 生物计算 · Molecular computing, or DNA (Deoxyribose Nucleic Acid) computing, is a new discipline of computer science. It s a novel method for massively parallel computation that can tackle NP-complete or non-deterministic polynomia…
• MOZAIC: compound growth via in silico reactions and global optimization using Conformational Space Annealing.
  2026 · AI 驱动科学发现 · Fragment-based drug discovery (FBDD) efficiently explores chemical space by combining small molecular fragments. Advances in computational methods are accelerating the development of algorithm- and AI-based approaches in…
• Cell-Free Synthetic Biology Platform for Engineering Synthetic Biological Circuits and Systems
  2019 · 生物计算 · Synthetic biology brings engineering disciplines to create novel biological systems for biomedical and technological applications. The substantial growth of the synthetic biology field in the past decade is poised to tra…
• Gene-Expressing Liposomes as Synthetic Cells for Molecular Communication Studies
  2019 · 生物计算 · The bottom-up branch of synthetic biology includes – among others – innovative studies that combine cell-free protein synthesis with liposome technology to generate cell-like systems of minimal complexity, often referred…
• New Applications of Synthetic Biology Tools for Cyanobacterial Metabolic Engineering
  2019 · 生物计算 · Cyanobacteria are promising microorganisms for sustainable biotechnologies, yet unlocking their potential requires radical re-engineering and application of cutting-edge synthetic biology techniques. In recent years, the…
• Control theory meets synthetic biology
  2016 · 生物计算 · The past several years have witnessed an increased presence of control theoretic concepts in synthetic biology. This review presents an organized summary of how these control design concepts have been applied to tackle a…
• Butyrolactone signalling circuits for synthetic biology
  2015 · 生物计算 · Signalling circuits based on quorum sensing mechanisms have been popular tools for synthetic biology. Recent advances in our understanding of the analogous systems regulating antibiotics production in soil bacteria sugge…
• Synthetic biology devices for in vitro and in vivo diagnostics
  2015 · 生物计算 · There is a growing need to enhance our capabilities in medical and environmental diagnostics. Synthetic biologists have begun to focus their biomolecular engineering approaches toward this goal, offering promising result…
• Synthetic biology devices and circuits for RNA-based ‘smart vaccines’: a propositional review
  2015 · 生物计算 · Nucleic acid vaccines have been gaining attention as an alternative to the standard attenuated pathogen or protein based vaccine. However, an unrealized advantage of using such DNA or RNA based vaccination modalities is …
• CMEIAS JFrad: A Digital Computing Tool to Discriminate the Fractal Geometry of Landscape Architectures and Spatial Patterns of Individual Cells in Microbial Biofilms
  2014 · 生物计算 · Image analysis of fractal geometry can be used to gain deeper insights into complex ecophysiological patterns and processes occurring within natural microbial biofilm landscapes, including the scale-dependent heterogenei…
• Co-culture systems and technologies: taking synthetic biology to the next level
  2014 · 生物计算 · Co-culture techniques find myriad applications in biology for studying natural or synthetic interactions between cell populations. Such techniques are of great importance in synthetic biology, as multi-species cell conso…
• Biomedically relevant circuit‐design strategies in mammalian synthetic biology
  2013 · 生物计算 · The development and progress in synthetic biology has been remarkable. Although still in its infancy, synthetic biology has achieved much during the past decade. Improvements in genetic circuit design have increased the …
• Identification of Relevant Genes with a Multi-Agent System using Gene Expression Data
  2012 · AI Agent 生态 · In recent years, technology for information extraction from gene activity in cells, has made an important breakthrough with the DNA microarrays. With this technology it is possible for researchers to know which genes are…
• &lt;title&gt;Modular Alignment System For Spacecraft&lt;/title&gt;
  2012 · AI 安全与对齐 · A modular alignment system has been designed and built at the Institut d'Astrophysique, Lige. Based on the multiple-beam autocollimation principle, it is composed of two collimators, a series of beam splitters and mirror…
• Arduino for Robotics
  2011 · 智慧农业 · With some of the basics of electricity, Arduino, and general robot building out of the way, we jump right in to some of the specific interfacing tasks that are needed to complete the projects in this book. In Chapter 1, …
• Engineering modular and orthogonal genetic logic gates for robust digital-like synthetic biology
  2011 · 生物计算 · Modular and orthogonal genetic logic gates are essential for building robust biologically based digital devices to customize cell signalling in synthetic biology. Here we constructed an orthogonal AND gate in Escherichia…
• Synthetic Biology Moving into the Clinic
  2011 · 生物计算 · Synthetic biology is an emerging field focused on engineering biomolecular systems and cellular capabilities for a variety of applications. Substantial progress began a little over a decade ago with the creation of synth…

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