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cell biology

GeneTech 知识引擎共收录 2571 篇相关科研实体，横跨 30 个垂直领域。数据来自 OpenAlex、arXiv、Crossref、PubMed、Europe PMC 等公开学术源，全部可溯源到原文。

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代表性文献（按质量分排序，前 60 条）

• Foliar-applied honokiol exhibits basipetal translocation, offering a strategy for root disease management in precision agriculture systems.
  2026 · 智慧农业 · Introduction Root diseases in crops are increasingly becoming the most difficult to control due to the challenge of fungicides reaching infection sites. Honokiol, a natural fungicidal product derived from Magnolia offici…
• Label-Free Impedance-Activated Acoustic Sorting of Cells From Structural to Molecular Scale in Microfluidics.
  2026 · AI 驱动科学发现 · Label-free, noninvasive, and high-throughput analysis and sorting of cells are essential capabilities in modern biomedicine, particularly for investigating cellular heterogeneity, functional phenotyping, and precision me…
• AI-guided prefusion stabilization of the human coronavirus OC43 spike protein enables universal embecovirus antigen design
  2026 · AI 安全与对齐 · The continued threat of zoonotic coronavirus spillovers underscores the need for cross-species applicable vaccine design strategies. The genus Embecovirus includes human coronaviruses OC43 and HKU1 as well as relevant ve…
• Tetrahydropalmatine has analgesic role in mouse model of bone cancer pain by inactivating the TNF-α/uPA/PAR2/TRPV1 pathway in dorsal root ganglia
  2025 · AI 驱动科学发现 · Background Treatment of bone cancer pain (BCP) remains a challenge. The current paper was to research the analgesic effect of Tetrahydropalmatine (THP) on BCP and the related mechanisms. Methods Mouse model of BCP was co…
• Chromosome alignment relies on spindle-localized control of Cdk1 activity
  2024 · AI 安全与对齐 · Abstract During mitosis, chromosome alignment at the mitotic spindle equator grants correct chromosome segregation and proper nuclei formation in daughter cells. A central role for chromosome alignment is exerted by the …
• ATM orchestrates ferritinophagy and ferroptosis by phosphorylating NCOA4
  2023 · AI Agent 生态 · Ferroptosis is a newly characterized form of programmed cell death, which is driven by the lethal accumulation of lipid peroxides catalyzed by the intracellular bioactive iron. Targeted induction of ferroptotic cell deat…
• Metastatic Epithelioid Trophoblastic Tumor Following Incomplete Methotrexate Therapy for Ectopic Pregnancy: A Case Report and Multimodal Management.
  2026 · AI Agent 生态 · Gestational trophoblastic neoplasia (GTN) comprises a spectrum of rare placental trophoblastic malignancies, including choriocarcinoma, placental site trophoblastic tumor, and the particularly uncommon epithelioid tropho…
• Resilient and privacy-preserving energy management system for multi-microgrids via an adaptive multi-agent system)
  2026 · AI Agent 生态 · Système de gestion de l'énergie résilient et avec protection de la vie privée pour les multi micro-réseaux via un système multi-agents adaptatif Au cours des dernières décennies, le monde a été témoin d'une augmentation …
• Shared navigation in a cybernetic multi-agent autonomous system
  2026 · AI Agent 生态 · Navigation partagée dans un système autonome cybernétique multi-agents Ma thèse porte sur la navigation partagée entre le système autonome et l'humain. Dans notre recherche, nous mettons l'accent sur la fusion des comman…
• Simulating Autonomous Agent in Connected Virtual Environments
  2026 · AI Agent 生态 · Simulation d’Agents Autonomes dans des Environnements Virtuels Connectés Comprendre le comportement humain est essentiel pour développer des systèmes adaptatifs tels que des environnements connectés. Des données réelles …
• A Multi-agent Based Multi-Layer Distributed Hybrid Planning Model for Demand Responsive Transport System Study
  2026 · AI Agent 生态 · Un modèle multi-agent distribué et hybride pour la planification du transport à la demande temps réel Durant ces dernières années, la congestion du trafic urbain et la pollution de l'air sont devenus d'énormes problèmes …
• Optimal Active Cyber Defence Strategies based on Multi-Agent System Verification
  2026 · AI Agent 生态 · Stratégies Optimales de Cybersécurité basées sur la Vérification Formelle de Systèmes Multi-Agents De nombreux systèmes informatiques et industriels sont conçus à un instant donné avec les outils et les connaissances de …
• Contribution to the modeling of technology transfer in green IT with multi-agent system
  2026 · AI Agent 生态 · Contributions à la modélisation avec un système multi agent du transfert technologique en Green IT Depuis 5 à 10 ans, les recherches sont nombreuses sur la réduction de l'énergie en l'informatique (principalement sur la …
• Contributions to Multi-agent System Control through Fixed-Time Distributed Optimization
  2026 · AI Agent 生态 · Contributions à la commande des systèmes multi-agents par optimisation distribuée à temps fixe Avec le développement de l'informatique distribuée et des réseaux à grande échelle au cours de la dernière décennie, l'optimi…
• Orchestration des activités d’apprentissage mobile
  2026 · AI Agent 生态 · L’apprentissage mobile est devenu un sujet d’intérêt car il implique de nombreux domaines de recherche concernant les contextes d’usages et de technologie complexes. En effet, ce type de formation a été reconnu pour sa c…
• Orchestration d'agents mobiles en communauté
  2026 · AI Agent 生态 · Ce travail de thèse a pour objectif la définition d'une plate-forme logicielle pour l'interprétation d'orchestrations sur un cluster de bus logiciels. Nous proposons une approche qui permet d'offrir une haute disponibili…
• Container Orchestration for the Edge Cloud
  2026 · AI Agent 生态 · Orchestration de conteneurs pour l'edge cloud Avec l'essor des infrastructures de type edge où les ressources informatiques sont en périphérie de réseau, la tendance est une fois de plus orientée vers la décentralisation…
• Contribution of ontology alignment to enterprise interoperability
  2026 · AI 安全与对齐 · Contribution à l'interopérabilité des entreprises par alignement d'ontologies Cette thèse propose l’utilisation de l’alignement d'ontologies pour contribuer à l'interopérabilité d’une fédération d’entreprises en se basan…
• Representing 3D models for alignment and recognition
  2026 · AI 安全与对齐 · Représentations de modèles 3D pour l’alignement et la reconnaissance Cette thèse explore différentes représentations de modèles 3D pour la mise en correspondance de formes 3D, l’alignement d’une instance 2D et de son mod…
• Confidence Measures for Alignment and for Machine Translation
  2026 · AI 安全与对齐 · Mesures de Confiance pour l’Alignement et pour la Traduction Automatique En linguistique informatique, la relation entre langues différentes est souventétudiée via des techniques d'alignement automatique. De tels alignem…
• Machine learning for beam alignment in mmWave networks
  2026 · AI 安全与对齐 · Apprentissage automatique pour l'alignement des faisceaux dans les réseaux à onde millimétrique Pour faire face à la croissance exponentielle du trafic des données mobiles, une solution possible est d'exploiter les large…
• Low-rank network models of neural computations
  2026 · AI 安全与对齐 · Réseaux de neurones de bas rang et calculs neuronaux À tout instant, des myriades de neurones coopèrent au sein d’un système nerveux, produisant des motifs d’activité collectifs qui forment un substrat biologique pour la…
• Incorporating physical knowledge into deep neural network
  2026 · AI 安全与对齐 · Incorporation de connaissance physique dans des réseaux de neurones profonds Un processus physique est un phénomène marqué par des changements graduels à travers une série d'états successifs se produisant dans le monde p…
• Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase
  2020 · AI Agent 生态 · Abstract Profound metabolic changes are characteristic of macrophages during classical activation and have been implicated in this phenotype. Here we demonstrate that nitric oxide (NO) produced by murine macrophages is r…
• Neutrophils promote the development of reparative macrophages mediated by ROS to orchestrate liver repair
  2019 · AI Agent 生态 · Abstract Phagocytes, including neutrophils and macrophages, have been suggested to function in a cooperative way in the initial phase of inflammatory responses, but their interaction and integration in the resolution of …
• An Endostatin-Lentivirus (ES-LV)-EPC Gene Therapy Agent for Suppression of Neovascularization in Oxygen-Induced Retinopathy Rat Models
  2019 · AI Agent 生态 · Abstract Background: Transplantation of gene transfected endothelial progenitor cells (EPCs) has provided novel methods for neovascularization but not ocular disease therapy. This study aimed to investigate the efficacy …
• Comparative analysis of the reactive oxygen species‐producing enzymatic activity of Arabidopsis NADPH oxidases
  2018 · AI 安全与对齐 · Summary Reactive oxygen species ( ROS ) produced by NADPH oxidases, called respiratory burst oxidase homologs (Rbohs), play crucial roles in development as well as biotic and abiotic stress responses in plants. Arabidops…
• Complement Receptor C5aR1 Plays an Evolutionarily Conserved Role in Successful Cardiac Regeneration
  2018 · AI 安全与对齐 · BACKGROUND: Defining conserved molecular pathways in animal models of successful cardiac regeneration could yield insight into why adult mammals have inadequate cardiac regeneration after injury. Insight into the transcr…
• NRF2 regulates endothelial glycolysis and proliferation with miR-93 and mediates the effects of oxidized phospholipids on endothelial activation
  2017 · AI 安全与对齐 · Phospholipids, such as 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine (PAPC), are the major components of cell membranes. Their exposure to reactive oxygen species creates oxidized phospholipids, which predispose…
• Molecular Regulation of Adipogenesis and Potential Anti-Adipogenic Bioactive Molecules
  2016 · AI Agent 生态 · Adipogenesis is the process by which precursor stem cells differentiate into lipid laden adipocytes. Adipogenesis is regulated by a complex and highly orchestrated gene expression program. In mammalian cells, the peroxis…
• Metalloprotease SPRTN/DVC1 Orchestrates Replication-Coupled DNA-Protein Crosslink Repair
  2016 · AI Agent 生态 · The cytotoxicity of DNA-protein crosslinks (DPCs) is largely ascribed to their ability to block the progression of DNA replication. DPCs frequently occur in cells, either as a consequence of metabolism or exogenous agent…
• Precision Agriculture and the Role of Remote Sensing: A Review
  2014 · 智慧农业 · L'agriculture de précision est basée sur l'intégration de nouvelles technologies telles que les systèmes d'information géographique (SIG), les systèmes de positionnement global (GPS) et la télédétection pour permettre au…
• Plasma membrane tension orchestrates membrane trafficking, cytoskeletal remodeling, and biochemical signaling during phagocytosis
  2013 · AI Agent 生态 · Phagocytes clear the body of undesirable particles such as infectious agents and debris. To extend pseudopods over the surface of targeted particles during engulfment, cells must change shape through extensive membrane a…
• Target of Rapamycin Regulates Development and Ribosomal RNA Expression through Kinase Domain in Arabidopsis
  2011 · AI 安全与对齐 · Target of rapamycin (TOR) is a central regulator of cell growth, cell death, nutrition, starvation, hormone, and stress responses in diverse eukaryotes. However, very little is known about TOR signaling and the associate…
• Geometric cues for directing the differentiation of mesenchymal stem cells
  2010 · AI Agent 生态 · Significant efforts have been directed to understanding the factors that influence the lineage commitment of stem cells. This paper demonstrates that cell shape, independent of soluble factors, has a strong influence on …
• Perturbation of survivin expression affects chromosome alignment and spindle checkpoint in mouse oocyte meiotic maturation
  2009 · AI 安全与对齐 · Survivin is a member of inhibitors of apoptosis proteins (IAPs), which have multiple regulatory functions in mitosis, but its roles in meiosis remain unknown. Here, we report its expression, localization and functions in…
• Inhibition of Tobacco Mosaic Virus Movement by Expression of an Actin-Binding Protein
  2009 · AI 安全与对齐 · The tobacco mosaic virus (TMV) movement protein (MP) required for the cell-to-cell spread of viral RNA interacts with the endoplasmic reticulum (ER) as well as with the cytoskeleton during infection. Whereas associations…
• Posttranscriptional Orchestration of an Anti-Apoptotic Program by HuR
  2007 · AI Agent 生态 · The RNA-binding protein HuR can stabilize and/or regulate the translation of target mRNAs, thereby affecting the cellular responses to immune, proliferative, and damaging agents. Here, we discuss emerging evidence that H…
• Dynamic Fluorescent Imaging of Human Immunodeficiency Virus Type 1 Gag in Live Cells by Biarsenical Labeling
  2005 · AI 安全与对齐 · Human immunodeficiency virus type 1 (HIV-1) Gag is the primary structural protein of the virus and is sufficient for particle formation. We utilized the recently developed biarsenical-labeling method to dynamically obser…
• Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1α/CXC chemokine receptor 4 pathway
  2004 · AI 安全与对齐 · Migration toward pathology is the first critical step in stem cell engagement during regeneration. Neural stem cells (NSCs) migrate through the parenchyma along nonstereotypical routes in a precise directed manner across…
• CELLULAR RESPONSES TO INTERFERON-γ
  1997 · AI Agent 生态 · Interferons are cytokines that play a complex and central role in the resistance of mammalian hosts to pathogens. Type I interferon (IFN-alpha and IFN-beta) is secreted by virus-infected cells. Immune, type II, or gamma-…
• Functional conservation of mouse Notch receptor family members
  1996 · AI 安全与对齐 · All the known members of the mouse Notch receptor family were examined for their biochemical function by interaction with a DNA binding protein RBP-Jkappa. mNotch2, mNotch3 and int3 (= mNotch4) were shown to interact wit…
• Interleukin-38 promotes alveolar bone repair in periodontitis by suppressing the nuclear factor kappa B pathway.
  2026 · AI Agent 生态 · Background Periodontitis, characterized by chronic inflammation and alveolar bone loss, poses significant challenges to oral health. Interleukin-38 (IL-38) has emerged as a potential therapeutic agent due to its anti-inf…
• Leucoseptoside a reverses multidrug resistance in breast cancer cells by targeting P-glycoprotein (P-gp/ABCB1) transporter.
  2026 · AI Agent 生态 · The overexpression of P-glycoprotein (P-gp) in tumour cells and its mediated drug efflux represent key mechanisms of cancer multidrug resistance (MDR). Natural compounds are attractive candidates for reversing MDR due to…
• CellSwarm-AD: A Multi-Scale Agent-Based Framework for Virtual Alzheimer's Disease Trials.
  2026 · AI Agent 生态 · Computational models of Alzheimer's disease (AD) rarely connect cellular heterogeneity, spatial tissue organization, pathology cascades, and pharmacological intervention within one auditable workflow. We present CellSwar…
• Adenosine Signaling in Primary and Metastatic Brain Tumors: Immune Suppression, Tumor Progression, and Therapeutic Opportunities.
  2026 · AI Agent 生态 · Brain tumors, whether primary or metastatic, remain a significant cause of cancer-related mortality and are characterized by a profoundly immunosuppressive tumor microenvironment (TME). Among the signaling pathways that …
• CRISPR/Cas12a-mediated allele engineering of <i>SmAPRR2</i> and <i>SmGLK2</i> reveals complementary control of fruit peel and flesh chlorophyll pigmentation in eggplant
  2026 · 智慧农业 · Eggplant ( Solanum melongena L.) displays extensive fruit color diversity, in which chlorophyll-related pigmentation contributes to both external appearance and market value. Previous genetic studies identified SmAPRR2 a…
• Role of vimentin in inhibiting akabane virus replication and its preliminary exploration of mechanisms involving autophagy and apoptosis.
  2026 · 智慧农业 · AKAV (Akabane virus), as a mosquito-borne virus, can cause abortions and stillbirths in pregnant ruminants, posing a threat to the global livestock industry. Vimentin (VIM), a key component of the IF cytoskeleton, plays …
• TaIAA25 negatively regulates wheat alkaline tolerance by inhibiting plasma membrane H&lt;sup&gt;+&lt;/sup&gt;-ATPase activity.
  2026 · 智慧农业 · Soil salinization/alkalization represents a universal challenge that severely constrains crop productivity. Elucidating the molecular mechanisms underpinning saline/alkaline tolerance of wheat ( Triticum aestivum ) holds…
• Antibody-Drug Conjugates Targeting HER2 and Trop-2: A New Force in Precision Treatment for Solid Tumors.
  2026 · 智慧农业 · Human epidermal growth factor receptor 2 (HER2) and trophoblast cell surface antigen 2 (Trop-2) are tumor-associated antigens widely overexpressed in multiple malignant tumors, which drive malignant proliferation, invasi…
• Edible coatings as modulators of enzymatic pathways in postharvest fruit metabolism - A comprehensive review.
  2026 · 智慧农业 · Postharvest fruit deterioration is governed by tightly coordinated enzymatic networks that regulate cell wall disassembly, carbohydrate conversion, and redox balance. Although edible coatings are widely applied to reduce…
• Disruption of cellular timekeeping in cancer: links between circadian clocks, metabolism, and tumor progression.
  2026 · 智慧农业 · Disruption of cellular timekeeping systems is a key driver of cancer cell development and progression. The circadian clock is a 24-hour regulatory system that relies on core clock genes - CLOCK, BMAL1, PER, and CRY. Main…
• Peptide hormones in shaping root system architecture and environmental adaptation: Current advances and translational perspectives.
  2026 · 智慧农业 · Root system architecture (RSA) is pivotal to plant nutrient acquisition and environmental adaptation. In recent years, peptide hormones-intercellular signaling molecules that act locally or systemically-have emerged as c…
• SOCS2 regulation myoblast differentiation of Hu sheep via STAT3/PSMB9 pathway.
  2026 · 智慧农业 · SOCS2 is known to regulate myoblast differentiation and skeletal muscle development via the GH-IGF1 axis, while its role in Hu sheep myoblast differentiation and its potential alternative signaling pathways remain largel…
• Analytical method development and validation of a serum LC-MS/MS assay for 2 emerging synthetic cannabinoids: 5F-MDMB-PICA and MDMB-4en-PINACA.
  2026 · 智慧农业 · Background This study aimed to develop and validate a highly sensitive and reproducible liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the simultaneous determination of 5F-MDMB-PICA and MDMB-4en-PIN…
• Integrated Comparative Genomics and Population Genomics Reveal the Genomic and Epigenomic Basis of Barley (&lt;i&gt;Hordeum vulgare&lt;/i&gt;) Evolution and Domestication.
  2026 · 智慧农业 · Barley ( Hordeum vulgare ) is one of the earliest domesticated cereal crops and remains important for global feed, food, and malting industries. Although high-quality genomic resources are now available, its large repeat…
• Multi-species Comparative Analysis Identifies Conserved Enhancers for Improving Casein Expression via Gene Editing.
  2026 · 智慧农业 · As the global population continues to grow, the demand for protein is correspondingly increasing. Milk serves as a significant source of high-quality protein, with casein being its primary nutrient. Consequently, the cul…
• A Study on the Effect of Copper Methionine in Alleviating Yellowing in Channel Catfish.
  2026 · 智慧农业 · An 8-week trial evaluated dietary copper methionine (CM) on body and flesh color in yellowed channel catfish. Basic diets were supplemented with CM at 0 (control, Cu1), 7 (Cu2), 14 (Cu3), 21 (Cu4), and 27 (Cu5) mg/kg, wi…
• Pyrroloquinoline quinone enhances in vitro maturation of porcine oocytes and supports ensuing embryonic development.
  2026 · 智慧农业 · Oxidative stress, driven by an imbalance between reactive oxygen species (ROS) production and antioxidant capacity (particularly glutathione, GSH), contributes significantly to the poor quality of in vitro maturation (IV…
• Intratracheal Lactobacillus rhamnosus attenuates poultry-house PM&lt;sub&gt;2.5&lt;/sub&gt;-induced lung inflammation in broilers by remodeling the pulmonary microbiota-metabolite axis.
  2026 · 智慧农业 · Fine particulate matter (PM 2.5 ) in intensive farming systems is a bioaerosol mixture that poses severe risks to respiratory health; however, the role of the lung microbiome in PM 2.5 -induced toxicity and its potential…

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