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intensive care medicine

GeneTech 知识引擎共收录 176 篇相关科研实体，横跨 15 个垂直领域。数据来自 OpenAlex、arXiv、Crossref、PubMed、Europe PMC 等公开学术源，全部可溯源到原文。

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• Artificial Intelligence in Cardiovascular Medicine: Focus on Hypertension
  2026 · AI 安全与对齐 · Hypertension remains the most prevalent modifiable risk factor for cardiovascular morbidity and mortality worldwide, yet rates of effective blood pressure control remain persistently suboptimal despite the availability o…
• Efficacy of synthetic and biological DMARDs: a systematic literature review informing the 2025 update of the EULAR recommendations for the management of rheumatoid arthritis
  2026 · 生物计算 · OBJECTIVES: This systematic literature review (SLR) updated evidence on the efficacy of disease-modifying antirheumatic drugs (DMARDs) and glucocorticoids (GCs) to inform the 2025 update of the European Alliance of Assoc…
• Smart Wound Dressings and the Biological Parameters They Monitor: A Scoping Review
  2026 · 生物计算 · Chronic wounds represent a major global health and economic burden. Smart wound dressings integrate biosensing and stimuli-responsive materials to monitor and modulate biological parameters within the wound microenvironm…
• Artificial intelligence in immunotherapy: revolutionizing diagnostic and therapeutic applications in cancer and autoimmune diseases
  2026 · 医疗人工智能 · Artificial intelligence (AI) is increasingly advancing precision immunotherapy by integrating high-dimensional biomedical data to support diagnosis, treatment selection, and longitudinal monitoring in both cancer and aut…
• Toward Timely Diagnosis of Pancreatic Cancer: Revolutionizing Early Detection Through Genomics, Artificial Intelligence, and Noninvasive Biomarkers
  2026 · 医疗人工智能 · BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive cancers, typically diagnosed at an advanced stage due to its subtle and often absent early symptoms. Despite representing only 3% of …
• Alzheimer's disease drug development pipeline: 2026.
  2026 · 脑科学 · INTRODUCTION: Discovery and development of new therapies for Alzheimer's disease (AD) are urgently needed to address the world's growing population of individuals on the AD pathophysiological continuum. Clinicaltrials.go…
• Reperfusion Therapy and Outcomes in High-Risk Pulmonary Embolism ― Multicenter Registry Study From the Tokyo Cardiovascular Care Unit Network ―
  2026 · 碳中和与 CCUS · Background: High-risk pulmonary embolism (PE) is associated with substantial mortality, and contemporary guidelines recommend prompt reperfusion therapy when feasible. However, real-world data describing how reperfusion …
• Predicting treatment outcomes by door-to-device time and baseline characteristics in STEMI patients undergoing PPCI: a cross-sectional study in southern Iran.
  2026 · 碳中和与 CCUS · BACKGROUND: Primary percutaneous coronary intervention (PPCI) is considered the gold standard for ST-elevation myocardial infarction (STEMI) treatment. While door-to-device (DTD) time critically influences outcomes, its …
• A study on drug utilization pattern of antiplatelet and anticoagulant drugs in the medicine department of a tertiary care teaching hospital
  2026 · 碳中和与 CCUS · Background: Antiplatelet and anticoagulant therapies are essential in the prevention and management of thromboembolic disorders, particularly cardiovascular and cerebrovascular diseases. Evaluation of prescribing pattern…
• A comprehensive review of venous thromboembolism risk assessment models for hospitalized medical patients: comparative evidence, implementation challenges, and future directions
  2026 · 碳中和与 CCUS · Venous thromboembolism (VTE) is a leading cause of preventable hospital-acquired morbidity and mortality. Despite the availability of effective prophylaxis, its application in clinical practice remains inconsistent, ofte…
• Challenges and potential of using digital biomarkers in healthcare and clinical trials
  2026 · 数字孪生 · Digital biomarkers use sensors and analytics, to offer continuous monitoring and personalized medicine. In this Perspective, we describe real-world use cases, such as glucose tracking to optimise insulin dosing and weara…
• Beyond snapshot dosing: a dynamic living digital twin framework for model-informed precision dosing in critical illness
  2026 · 数字孪生 · INTRODUCTION: Model-Informed Precision Dosing (MIPD) has improved individualized therapy, but in critical illness its reliance on intermittently updated data creates a temporal mismatch between pharmacokinetic (PK) model…
• Digital Twins in Neonatology: Current Applications and Future Directions: A Narrative Review
  2026 · 数字孪生 · Digital Twins (DTs) are virtual, patient-specific representations that integrate real-time data to model, predict, and optimize biological and clinical processes. In neonatology, DTs are gaining attention as powerful too…
• Digital Twins in Neonatology: Current Applications and Future Directions. A Narrative Review
  2026 · 数字孪生 · Digital Twins (DTs) are virtual, patient-specific representations that integrate re-al-time data to model, predict, and optimize biological and clinical processes. In neo-natology, DTs are gaining attention as powerful t…
• AI-Based Predictive Models for Cardiogenic Shock in STEMI: Real-World Data for Early Risk Assessment and Prognostic Insights
  2025 · AI 安全与对齐 · Background: Cardiogenic shock (CS) is a life-threatening complication of ST-elevation myocardial infarction (STEMI) and remains the leading cause of in-hospital mortality, with rates ranging from 5 to 10% despite advance…
• Explainable AI unravels sepsis heterogeneity via coagulation-inflammation profiles for prognosis and stratification
  2025 · AI 安全与对齐 · Sepsis is a leading cause of hospital mortality, and its significant heterogeneity complicates prognosis and stratification. To address this challenge, we developed an explainable artificial intelligence prognostic model…
• Current perspectives and challenges of using artificial intelligence in immunodeficiencies
  2025 · AI 安全与对齐 · The rapid growth of artificial intelligence (AI) in health care is promising for screening and early diagnosis in settings that heavily rely on professional expertise, such as rare diseases like inborn errors of immunity…
• Biologics in severe asthma: a state-of-the-art review
  2025 · 生物计算 · Asthma is considered severe if it remains uncontrolled despite optimal conventional therapy, characterised by poor symptom control, frequent exacerbations and increased exposure to systemic corticosteroids. This has a si…
• 2025 ESC/EACTS Guidelines for the management of valvular heart disease
  2025 · 生物计算 · The European Society of Cardiology (ESC)/European Association for Cardio-Thoracic Surgery (EACTS) Guidelines represent the views of the ESC and the EACTS and were produced after careful consideration of the scientific an…
• European Society for the Study of Coeliac Disease 2025 Updated Guidelines on the Diagnosis and Management of Coeliac Disease in Adults. Part 1: Diagnostic Approach
  2025 · 生物计算 · INTRODUCTION: Since the publication of the first European Society for the Study of Coeliac Disease (ESsCD) guidelines in 2019, significant advancements have emerged in the diagnosis of coeliac disease (CeD) in adults. Th…
• Consensus on the diagnosis and treatment of adult necrotizing fasciitis (2025 edition)
  2025 · 生物计算 · Abstract Necrotizing fasciitis (NF) is a disease characterized by severe infection of the skin and its underlying soft tissues as the initial symptom. NF is known for its difficulty in early diagnosis and rapid progressi…
• Inborn errors of immunity: Manifestation, treatment, and outcome—an ESID registry 1994–2024 report on 30,628 patients
  2025 · 生物计算 · The European Society for Immunodeficiencies patient registry (ESID-R), established in 1994, is one of the world's largest databases on inborn errors of immunity (IEI). IEI are genetic disorders predisposing patients to i…
• Real-World Effectiveness of Biologic Therapy in Allergic Bronchopulmonary Aspergillosis
  2025 · 生物计算 · BACKGROUND: Allergic bronchopulmonary aspergillosis (ABPA) is characterized by a severe hypersensitivity reaction to Aspergillus species. Current treatment relies on oral corticosteroids (OCS) and triazole antifungal the…
• Antibiotics and Artificial Intelligence: Clinical Considerations on a Rapidly Evolving Landscape
  2025 · 医疗人工智能 · The growing interest in leveraging artificial intelligence (AI) tools for healthcare decision-making extends to improving antibiotic prescribing. Large language models (LLMs), a type of AI trained on extensive datasets f…
• Improving Sepsis Prediction in the ICU with Explainable Artificial Intelligence: The Promise of Bayesian Networks
  2025 · 医疗人工智能 · Background/Objectives: Sepsis remains one of the leading causes of mortality worldwide, characterized by a complex and heterogeneous clinical presentation. Despite advances in patient monitoring and biomarkers, early det…
• Federated Learning Lifecycle Management for Distributed Medical Artificial Intelligence Applications: A Case Study on Post-Transcatheter Aortic Valve Replacement Complication Prediction Solution
  2025 · 医疗人工智能 · The evolution of artificial intelligence (AI) has unveiled considerable prospects for delivering efficacious solutions in the medical domain. Nevertheless, existing legal frameworks and concerns regarding data privacy as…
• Performance of a novel medical artificial intelligence large language model on supporting decision-making for emergency patients with suspected sepsis.
  2025 · 医疗人工智能 · BACKGROUND: Large language models (LLMs) are being explored for disease prediction and diagnosis; however, their effi cacy for early sepsis identifi cation in emergency departments (EDs) remains unexplored.This study aim…
• The Role of Artificial Intelligence in Early Diagnosis and Management of Cardiovascular Diseases
  2025 · 医疗人工智能 · The increasing rate of cardiovascular diseases (CVDs) has posed a tremendous challenge to their early detection and personalized treatment. This research examines the potential of Artificial Intelligence (AI) for early d…
• Role of Artificial Intelligence in Congenital Heart Disease and Interventions
  2025 · 医疗人工智能 · Artificial intelligence has promising impact on patients with congenital heart disease, a vulnerable population with life-long health care needs and, often, a substantially higher risk of death than the general populatio…
• Evaluating the Role of Artificial Intelligence in Making Clinical Decisions for Treating Acute Pancreatitis
  2025 · 医疗人工智能 · Background/Objectives: Acute pancreatitis (AP) is an illness that requires prompt diagnosis and treatment since it has the potential to become life-threatening. The American College of Gastroenterology 2024 (ACG24) guide…
• Pressure Injury Prediction in Intensive Care Units Using Artificial Intelligence: A Scoping Review
  2025 · 医疗人工智能 · Background/Objetives: Pressure injuries pose a significant challenge in healthcare, adversely impacting individuals’ quality of life and healthcare systems, particularly in intensive care units. The effective identificat…
• Artificial Intelligence in Anaesthesiology: Current Applications, Challenges, and Future Directions
  2025 · 医疗人工智能 · Artificial intelligence (AI) is rapidly transforming anaesthesiology through advances in machine learning, deep learning, and large language models. AI-driven tools now contribute to nearly every phase of perioperative c…
• The Role of Artificial Intelligence in the Diagnosis and Management of Diabetic Retinopathy
  2025 · 医疗人工智能 · Background/Objectives: Diabetic retinopathy (DR) is a progressive microvascular complication of diabetes mellitus and a leading cause of vision impairment worldwide. Early detection and timely management are critical in …
• Artificial intelligence based multispecialty mortality prediction models for septic shock in a multicenter retrospective study
  2025 · 医疗人工智能 · Septic shock is one of the most lethal conditions in ICU, and early risk prediction may help reduce mortality. We developed a TOPSIS-based Classification Fusion (TCF) model to predict mortality risk in septic shock patie…
• The Future of Enhanced Recovery After Surgery in General Surgery: Integrating Artificial Intelligence, Personalized Care, and Technological Advances
  2025 · 医疗人工智能 · Enhanced Recovery After Surgery (ERAS) protocols have changed and improved surgical care and practice, transforming classic approaches toward more evidence-based practices. ERAS protocols demonstrate consistent benefits,…
• New tools for diagnosis of primary immunodeficiencies: from awareness to artificial intelligence
  2025 · 医疗人工智能 · Primary immune deficiencies (PI) are rare diseases associated with frequent, severe infections, inflammatory and autoimmune diseases and/or cancer. Because of the variability in presentation, undiagnosed PI patients can …
• Artificial Intelligence Models in Diagnosis and Treatment of Kidney Diseases: Current Status and Prospects
  2025 · 医疗人工智能 · Background: Artificial intelligence (AI) has made significant advances in nephrology, revolutionizing the diagnosis, prognosis, and treatment of kidney diseases. Summary: This review provides an overview of AI applicatio…
• From traditional to artificial intelligence-driven approaches: Revolutionizing personalized and precision nutrition in inflammatory bowel disease
  2025 · 医疗人工智能 · Inflammatory bowel disease (IBD), comprising ulcerative colitis and Crohn's disease, is a chronic inflammatory condition with global prevalence and varying incidence. The IBD pathogenesis involves intricate interactions …
• Antimicrobial use and resistance
  2025 · 医疗人工智能 · Antimicrobial resistance affects the delivery of safe and effective healthcare. Antimicrobial resistance has attracted strong political focus, with the 2024 United Nations General Assembly high level meeting providing a …
• A novel approach to the prevention and management of cardiovascular diseases: targeting brain–heart axis
  2025 · 仿生智能 · Epidemiological studies indicate that cardiovascular diseases are the leading cause of death and disability worldwide, imposing a significant socioeconomic burden. Despite continuous medical advancements and new preventi…
• Precision therapies for genetic epilepsies in 2025: Promises and pitfalls
  2025 · 脑科学 · By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug-resistant epilepsies, including developmental and epileptic encephalopathies. Unlike con…
• Recent Advances in the Therapeutic Potential of Cannabinoids Against Gliomas: A Systematic Review (2022–2025)
  2025 · 脑科学 · ABSTRACT Glioma is the most common and lethal primary brain tumor in adults, with glioblastoma (GBM) representing the most aggressive subtype, characterized by diffuse infiltration, resistance to therapy, and a poor prog…
• Blood-Based Biomarkers for Improved Characterization of Traumatic Brain Injury: Recommendations from the 2024 National Institute for Neurological Disorders and Stroke Traumatic Brain Injury Classification and Nomenclature Initiative Blood-Based Biomarkers Working Group
  2025 · 脑科学 · A 2022 report by the National Academies of Sciences, Engineering, and Medicine called for a Traumatic Brain Injury (TBI) Classification Workshop by the National Institutes of Health (NIH) to develop a more precise, evide…
• Chronic subdural haematoma: a UK cost description analysis
  2025 · 脑科学 · PURPOSE: Chronic subdural haematoma (cSDH) is a prevalent neurosurgical condition with an increasing incidence. Most cSDH occur in patients with complex perioperative needs and emerging clinical practice guidelines could…
• Updates on neonatal cell and novel therapeutics: Proceedings of the Second Neonatal Cell Therapies Symposium (2024)
  2025 · 脑科学 · Cell therapies as treatments for neonatal conditions have attracted significant research and parent interest over the last two decades. Mesenchymal stromal cells, umbilical cord blood cells and neural stem cells translat…
• Steroid‐Induced Cardiomyopathy: Insights From a Systematic Literature Review and a Case Report
  2025 · 碳中和与 CCUS · Anabolic-androgenic steroids (AAS) abuse is associated with severe cardiovascular risks, particularly AAS-induced cardiomyopathy. This systematic review highlights that most cases show left ventricular dilation and reduc…
• Nursing Management of Cardiogenic Shock Patients With Mechanical Circulatory Support: A Scoping Review
  2025 · 碳中和与 CCUS · BACKGROUND: Despite limited evidence on nursing interventions for cardiogenic shock (CS) patients with mechanical circulatory support (MCS), nurses play a key role in ensuring device function, monitoring and preventing c…
• Analysis of the etiological characteristics of multidrug-resistant organisms and prognostic factors in ICU patients
  2025 · 碳中和与 CCUS · Background Multidrug-resistant organism (MDRO) infections contribute to high mortality in intensive care unit (ICU) patients, yet their specific pathogen profile and mortality risk factors are inadequately characterized.…
• Age-Specific Differences in Non-Surgical Patients Requiring Intensive Care ― Trends and Prognostic Impact During the Past Decade ―
  2025 · 碳中和与 CCUS · BACKGROUND: This study aimed to elucidate the age trends among non-surgical patients requiring intensive care over a 10-year period and the prognostic impact of aging in relation to their underlying etiologies. METHODS A…
• Adherence Towards Ventilator Associated Pneumonia Guidelines of Nurses Working in Critical Care
  2025 · 碳中和与 CCUS · Ventilator-associated pneumonia (VAP) is a significant cause of morbidity and mortality in critically ill patients. Nurses' adherence to VAP prevention guidelines plays a critical role in reducing the incidence of this i…
• Intravenous Medication Administration Errors in Hospitalised Patients: An Updated Systematic Review
  2025 · 碳中和与 CCUS · BACKGROUND: Administering intravenous (IV) drugs carries a high risk of adverse effects due to their direct entry into circulation. Identifying the prevalence and types of IV administration errors and the drugs involved …
• Acute Myocardial Infarction: Molecular Pathogenesis, Diagnosis, and Clinical Management
  2025 · 碳中和与 CCUS · Acute myocardial infarction (AMI) is a cardiovascular disease characterized by myocardial necrosis resulting from acute coronary artery occlusion. Although standardized diagnostic and therapeutic protocols have markedly …
• Impacts of air pollutions on cardiovascular and cerebrovascular diseases through inflammation: a comprehensive analysis of one million Chinese and half million UK individuals
  2025 · 碳中和与 CCUS · Epidemiological studies have found an association between air pollution and cardiovascular and cerebrovascular diseases (CACD) and its subtypes. However, there is a lack of individual-level data to explore the associatio…
• Chinese stroke association guidelines on reperfusion therapy for acute ischaemic stroke 2024
  2025 · 生命科学 · BACKGROUND: Stroke remains a major global health challenge, with China experiencing a significant burden due to its high incidence and severe outcomes. Reperfusion therapies, such as intravenous thrombolysis and endovasc…
• American Society of Hematology 2025 guidelines for treating newly diagnosed acute myeloid leukemia in older adults
  2025 · 量子材料 · BACKGROUND: Older adults with acute myeloid leukemia (AML) represent a cancer population in which disease-based risk factors, comorbidities, patient goals, and treatment risks and benefits influence treatment recommendat…
• Recent Advances in the Therapeutic Potential of Cannabinoids Against Gliomas: A Systematic Review (2022–2025)
  2025 · 合成生物与生物制造 · ABSTRACT Glioma is the most common and lethal primary brain tumor in adults, with glioblastoma (GBM) representing the most aggressive subtype, characterized by diffuse infiltration, resistance to therapy, and a poor prog…
• Bone Regeneration: A Review of Current Treatment Strategies
  2025 · 合成生物与生物制造 · Bone regeneration has emerged as a critical research and clinical advancement field, fueled by the growing demand for effective treatments in orthopedics and oncology. Over the past two decades, significant progress in b…
• Evaluation and mitigation of the limitations of large language models in clinical decision-making
  2024 · AI 安全与对齐 · Clinical decision-making is one of the most impactful parts of a physician's responsibilities and stands to benefit greatly from artificial intelligence solutions and large language models (LLMs) in particular. However, …
• Exploring Definitions and Predictors of Severe Asthma Clinical Remission after Biologic Treatment in Adults
  2024 · 生物计算 · Abstract Rationale There is no consensus on criteria to include in an asthma remission definition in real life. Factors associated with achieving remission after biologic initiation remain poorly understood. Objectives T…
• Consensus on the treatment of second-degree burn wounds (2024 edition)
  2024 · 生物计算 · Second-degree burns are the most common type of burn in clinical practice and hard to manage. Their treatment requires not only a consideration of the different outcomes that may arise from the dressing changes or surgic…

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