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biotechnology

GeneTech 知识引擎共收录 5205 篇相关科研实体，横跨 30 个垂直领域。数据来自 OpenAlex、arXiv、Crossref、PubMed、Europe PMC 等公开学术源，全部可溯源到原文。

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• Artificial Intelligence-Driven Plant Disease Detection and Diagnosis: A Comprehensive Review of Deep Learning Approaches, Multimodal Sensing Technologies, and Future Perspectives in Precision Agriculture.
  2026 · 智慧农业 · Plant diseases remain a major threat to global food production, causing significant yield losses and economic impact worldwide. Early and precise disease detection is crucial for effective crop management, yet convention…
• Variable Rate Nitrogen Application in Wheat Based on UAV Derived Fertilizer Maps and Precision Agriculture Technologies
  2025 · 智慧农业 · Variable-rate nitrogen (VR-N) application allows farmers to optimize nitrogen (N) input site-specifically within field boundaries, enhancing both economic efficiency and environmental sustainability. In this study, VR-N …
• PubChat: An Autonomous AI Agent for Zero Citation Hallucination, High-Recall PubMed Evidence Retrieval
  2026 · AI Agent 生态 · Background: The rapid growth of biomedical literature has rendered traditional systematic reviews unsustainable. Although large language models (LLMs) offer automation potential, citation fabrication and unreliable evide…
• Integrating stability zones and machine learning for enhanced crop management
  2026 · 智慧农业 · Abstract Purpose Sustainable agriculture requires both high and stable crop yields. Whilegenotype-environment-management (G×E×M) interactions influence yield stability, implementingsuch understanding into practical appli…
• Enhancing Precision Agriculture: Deep Learning for Rice Leaf Disease Identification
  2025 · 智慧农业 · Although rice is a major crop in many countries, its stability depends on the ongoing health test to ensure food supply and develop permanent growing practices. Economic security and higher agricultural output are the ou…
• Comparative Study of Plant Leaves Detection for Precision Agriculture using Machine Learning Techniques
  2025 · 智慧农业 · Crop production is an important factor in a country’s economic growth. The production of plants is greatly reduced by plant illnesses, which further decrease the quality of plants while charging farmer’s funds. The diffe…
• Comparative Analysis of YOLOv11 and YOLOv12 for Automated Weed Detection in Precision Agriculture
  2025 · 智慧农业 · This paper presents a comparative analysis of YOLOv11 and YOLOv12 for automated weed detection in precision agriculture. The primary objective is to assess both models' detection accuracy, generalization ability, and rel…
• Vegetation Indices from UAV Imagery: Emerging Tools for Precision Agriculture and Forest Management
  2025 · 智慧农业 · Unmanned Aerial Vehicles (UAVs) have become essential instruments for precision agriculture and forest monitoring, offering rapid, high-resolution data collection over wide areas. This review synthesizes global advances …
• Precision weeding in sugar beet farming: UAV monitoring of robotic systems
  2025 · 智慧农业 · Weeding robots are revolutionizing sugar beet farming. The performance of these systems is typically evaluated based on weed control efficacy (WCE), crop damage, and herbicide savings. While robots demonstrate WCE compar…
• Strategic manipulation of preferences in the rank minimization mechanism
  2024 · AI Agent 生态 · Abstract We consider one-sided matching problems, where agents are allocated items based on stated preferences. Posing this as an assignment problem, the average rank of obtained matchings can be minimized using the rank…
• Hyperspectral image feature extraction and classification for soil nutrient mapping
  2024 · 智慧农业 · Aerial hyperspectral images were used for soil nutrient mapping and the image processing results were compared with the conventional field grid sampling and interpolation methods. A spatial low pass filter was applied to…
• Within-field yield stability and gross margin variations across corn fields and implications for precision conservation
  2023 · 智慧农业 · Abstract Soil spatial variability is a primary contributor to within-field yield variation across farms. Spatio-temporal yield stability and variability can be assessed through multi-year yield monitor data and geostatis…
• Spatial and dynamic distribution of Chrysoperla spp. and Leucoptera coffeella populations in coffee Coffea arabica L
  2023 · 智慧农业 · Leucoptera coffeella (Guérin-Mèneville, 1842) (Lepidoptera: Lyonetiidae) is one of the main pests of coffee. Controlling this insect requires effective management methods, prevention of insecticide resistance from overus…
• Metastatic Epithelioid Trophoblastic Tumor Following Incomplete Methotrexate Therapy for Ectopic Pregnancy: A Case Report and Multimodal Management.
  2026 · AI Agent 生态 · Gestational trophoblastic neoplasia (GTN) comprises a spectrum of rare placental trophoblastic malignancies, including choriocarcinoma, placental site trophoblastic tumor, and the particularly uncommon epithelioid tropho…
• Graduate Student Literature Review: Rethinking concentrate feeding strategies for precision nutrition in lactating dairy cattle.
  2026 · 智慧农业 · The dairy industry in the United States has undergone significant intensification over the past several decades, resulting in improved nutrient use efficiency and economic gains, largely driven by genetic selection, impr…
• EVOLVING ARCHITECTURES AND LONG-HORIZON PLANNING IN MULTI-AGENT CONVERSATIONAL AI: A DECADE IN REVIEW
  2025 · AI Agent 生态 · This systematic review surveys advances in conversational AI from 2015 to 2025, focusing on the emergence of modular multi-agent architectures, hierarchical reinforcement learning, and self- evolving agents. A quantitati…
• Precision Pathway Engineering in Plants: Enhancing Crop Resilience and Productivity for Sustainable Agriculture
  2024 · 智慧农业 · Recent advancements in metabolic engineering have opened new avenues for addressing critical challenges in agriculture, nutrition, and sustainability. This study explores innovative strategies for manipulating plant meta…
• Precision Agriculture Decision Support Using Machine Learning
  2024 · 智慧农业 · The agricultural sector stands as the cornerstone of the Indian economy, with farmers often faced with the critical decision of selecting the most appropriate crop to cultivate based on multifaceted considerations such a…
• Network Science and Machine Learning for Precision Nutrition
  2023 · 智慧农业 · Nutrition is a significant factor in determining our health that is directly under our control, affecting our risk of chronic conditions like diabetes, heart disease , and cardiovascular diseases. Yet, the nutritional re…
• Precision nitrogen management strategy for winter wheat in the North China Plain based on an active canopy sensor
  2015 · 智慧农业 · The objective of this research was to develop a precision nitrogen (N) management strategy for winter wheat using a Crop Circle ACS-470 sensor and compare it with the GreenSeeker sensor-based precision N management strat…
• Investigation of Temporal and Spatial Variability for Green Tea Growth Using Precision Agriculture Technology
  2014 · 智慧农业 · Spatial and temporal variability of new shoots (number of shoots, dry mass and nitrogen concentration) were investigated under several conditions using precision agriculture technology. The growth and spatial variability…
• Flowering estimation in apple orchards by image analysis
  2013 · 智慧农业 · Tree-specific management practice related to individual tree physiological condition is necessary for higher quality and quantity in apple fruit production. Detection of apple flowering abundance based on analysis of HSL…
• Digital infrared thermography for monitoring canopy health of wheat
  2007 · 智慧农业 · Computer-aided diagnosis and prognosis models have been used for management decisions in crop protection. Initial infection rate, temperature and leaf wetness are important parameters in disease epidemiology and for deci…
• AERO: An AI Agent for Adaptive Eligibility Refinement and Optimization of Clinical Trial Criteria in Real-World Trial Emulation
  2026 · AI Agent 生态 · Randomized controlled trials (RCTs) provide high internal validity but often rely on restrictive eligibility criteria that limit generalizability and complicate real-world trial emulation. We propose AERO (AI Agent for A…
• Accelerated drug development using a digital formulator and a self-driving tableting data factory.
  2026 · AI Agent 生态 · Advances in drug discovery and clinical research have shifted the bottleneck in medicines development to chemistry, manufacturing, and controls activities, a critically step for regulatory approval. This includes formula…
• Pharmacovigilance Assistant: An Agentic Workflow for Reproducible Drug Safety Summaries.
  2026 · AI Agent 生态 · We present an agentic workflow that converts heterogeneous safety evidence into concise, reproducible drug summaries. While automated FAERS summarization, retrieval-augmented generation, and tool-driven agents exist in i…
• Agentic Artificial Intelligence for Hospital Readmission Review: A Single-Center Blinded Evaluation and Exploratory Qualitative Analysis
  2026 · AI Agent 生态 · Background Manual review of 30-day hospital readmissions can identify actionable quality and safety problems, but it is labor-intensive. We developed and evaluated an agentic AI workflow for evidence-grounded readmission…
• Physician-Reported Safety Outcomes of AI-Generated Hospital Course Summaries.
  2026 · AI Agent 生态 · Importance High-quality discharge summaries are essential for safe care transitions but contribute substantially to clinician documentation burden and burnout. While retrospective studies suggest that large language mode…
• PLGA - encapsulated harmine derivative H-2-168: A promising therapeutic agent for mitigating liver damage in hepatic hydatid disease.
  2026 · AI Agent 生态 · Harmine (HM), a bioactive alkaloid, exhibits remarkable antiparasitic potency. Nevertheless, its translational potential is substantially constrained by neurotoxicity, necessitating the development of safer analogs. H-2-…
• Laboratory Toxicity and Field Efficacy of Four Microbial-Derived Pesticides Combined with Two Adjuvants Against <i>Lygus pratensis</i> (Hemiptera: Miridae).
  2026 · AI Agent 生态 · Systematic field data on adjuvant-amended microbial-derived pesticides against L. pratensis in arid, high-ultraviolet cotton regions remain scarce. This study systematically evaluated the laboratory toxicity and field ef…
• The MID1IP1/S100A10-mGluR5 Axis in Seizures: Immune-Metabolic Crosstalk and Enhanced Therapeutic Efficacy of Benfotiamine/Phenytoin Combination.
  2026 · AI Agent 生态 · Introduction Epilepsy, characterized by recurrent seizures, is associated with dysregu-lated Fatty Acid (FA) metabolism and metabotropic glutamate receptor 5 (mGluR5) signaling. However, the contribution of FA metabolism…
• Research on the Highly Efficient and Low-Dose Improvement of Alcohol-Induced Liver Injury by High-Selenium-Content Modified Lycium barbarum Polysaccharides.
  2026 · AI Agent 生态 · There are currently no FDA-approved drugs for the treatment of alcohol-related liver diseases (ALD) due to their lack of effectiveness. Selenium-modified Lycium barbarum polysaccharides (SeLBP), as a promising agent for …
• Development and Evaluation of Artificial Intelligence–Assisted Decision Support System for Public Health Emergency Classification and Escalation in Kenya
  2026 · AI Agent 生态 · Background Timely assessment, classification, and escalation of public health events are essential for effective outbreak response, yet decision-making after event detection remains challenging because of fragmented guid…
• HistAgent: an evidence-grounded agent for spatial molecular reasoning from routine histology
  2026 · AI Agent 生态 · Abstract Routine hematoxylin and eosin (H&E) staining is a widely used histology test in clinical practice and biomedical research, but it does not provide direct spatial molecular information. Spatial transcriptomics (S…
• AI-driven discovery of bronopol for the treatment of pulmonary fibrosis via inhibition of fibroblast activation.
  2026 · AI Agent 生态 · Aims Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease with limited therapeutic options. Epigenetic regulation by p300 histone acetyltransferase plays a central role in fibroblast activation and fi…
• Multifunctional Nano-Contrast Agent Carriers: From Traditional Platforms to Next-Generation Theranostic Applications in Molecular Imaging.
  2026 · AI Agent 生态 · Multifunctional nano-contrast agent carriers are redefining molecular imaging by combining high-fidelity visualization with targeted delivery, controlled release, and, increasingly, therapeutic action. This review encomp…
• Therapeutic Interaction Features of AI Chatbots in Depression Interventions: Systematic Review and Meta-Analysis.
  2026 · AI Agent 生态 · Background Depression is a prevalent mental health disorder and a leading cause of disability worldwide, creating substantial personal and societal burdens. Digital mental health interventions have emerged as accessible …
• Subcutaneous drug delivery of high concentration antibody products - part 2: formulation, device options, and clinical bridging strategies for patient-centric commercial presentations.
  2026 · AI Agent 生态 · The landscape of drug delivery is undergoing a transformative shift. As demand for large-volume subcutaneous (SC) biologics continues to surge, the race to develop smarter, patient-centered combination drug products has …
• Precision oncology in the age of AI: lessons from AI-driven drug discovery and clinical translation.
  2026 · AI Agent 生态 · Drug discovery has been constrained by extended timelines and high costs, as the cumulative requirements of preclinical validation, multi-phase clinical trials, and regulatory approval have been imposed. Recently, comput…
• Navigating the Evolution of Urothelial Carcinoma Treatment: From Chemotherapy to Immunotherapy.
  2026 · AI Agent 生态 · Background The urothelial carcinoma (UC) trial landscape has expanded over two decades, alongside a shift from chemotherapy to immunotherapy and targeted approaches. We characterized temporal patterns in trial phase, int…
• Probiotics: multifunctional microorganisms for human health and biotechnological applications.
  2026 · AI Agent 生态 · Probiotics are live microorganisms that, when ingested in sufficient amounts, can have a beneficial impact on health. As crucial agents in maintaining gut homeostasis, enhancing immunity, and preventing of numerous disea…
• Association Between Endocrine Therapy and Fracture Risk in Women with Breast Cancer in Germany-A Retrospective Cohort Study.
  2026 · AI Agent 生态 · Background Aromatase inhibitors (AIs) are widely used in hormone receptor-positive breast cancer but may adversely affect bone health. Evidence on their independent association with fracture risk compared with tamoxifen …
• Beyond the Stent ("Leave-Nothing-Behind") Drug-Coated Balloons in Acute Coronary Syndrome: A Narrative Review.
  2026 · AI Agent 生态 · Background : Drug-coated balloons (DCBs) have emerged as a "leave-nothing-behind" strategy in percutaneous coronary intervention (PCI), with potential advantages over drug-eluting stents (DES) in selected patients with a…
• AI counseling agent for motivational interviewing: Conversational processes associated with change talk in emergency department patients.
  2026 · AI Agent 生态 · Background Large language models (LLMs) have the potential to expand access to Motivational Interviewing (MI), but little is known about whether AI-delivered counseling reproduces conversational processes associated with…
• Shrimp Aquaculture Under Viral Threats: Insights into Pathogens and Control Strategies.
  2026 · AI Agent 生态 · Viral diseases are among the most serious threats to shrimp aquaculture, causing large-scale mortality and production losses. This review summarizes current knowledge on the major viral diseases affecting cultured penaei…
• Artificial Intelligence Centrality in Psychotic Delusions and Violence Risk in Forensic Psychiatry: Retrospective Observational Study of Judicial Decisions.
  2026 · AI Agent 生态 · Background Artificial intelligence (AI)-themed delusions are increasingly observed in psychotic-spectrum disorders, reflecting the incorporation of contemporary sociotechnical elements into delusional systems. However, i…
• Insights into the conversion of odor compounds by a novel microbial agent during swine manure storage: a multi-omics integration of microbiome, metabolome and genome.
  2026 · AI Agent 生态 · Deep-pit manure storage in intensive swine farming has emerged as a major source of malodorous emissions, posing significant environmental and public health concerns. This study developed a targeted microbial agent by sy…
• Neurosymbolic Multi-Agent Large Language Model System Versus Specialist Physicians in COPD and Asthma Management: A Comparative Performance Evaluation Using Guideline-Based Clinical Vignettes
  2026 · AI Agent 生态 · Abstract Background Chronic obstructive pulmonary disease (COPD) and asthma collectively affect over 500 million individuals worldwide and represent leading causes of respiratory-related morbidity, healthcare utilization…
• A Synthetic Minimal Genome Design Framework for Bacteriophages: Application to <em>Streptococcus mutans</em> and Broad-Host-Range Expression in <em>Escherichia coli</em>
  2026 · AI Agent 生态 · Minimal genome design, reducing a system to its smallest functional part set, is a core synthetic-biology strategy. Bacteriophages are attractive but underused chassis, yet wild-type phages are difficult to engineer. We …
• [Analysis on the incidence and perioperative outcomes of immune-related adverse events in preoperative immunotherapy for colorectal cancer based on multicenter real-world data].
  2026 · AI Agent 生态 · Objective: To investigate the incidence of immune-related adverse events (irAEs) and corresponding perioperative outcomes among patients with colorectal cancer who received neoadjuvant immunotherapy and underwent curativ…
• Multi-Target-Directed Ligands (MTDLs) as Potential Therapeutic Candidates Targeting Multiple Pathogenic Factor of Alzheimer's Disease.
  2026 · AI Agent 生态 · Background Alzheimer's disease (AD) is the most common cause of dementia and a chronic neurodegenerative disorder in older adults. AD is not driven by a single factor but by the interaction of multiple pathological proce…
• Toxicological profiling of clinically used chemotherapeutics in zebrafish &lt;i&gt;(Danio rerio)&lt;/i&gt; larvae.
  2026 · AI Agent 生态 · Zebrafish patient-derived xenografts (zPDX) are a powerful emerging platform for personalized oncology, offering a rapid in vivo system for high-throughput chemoprofiling. Recent studies have demonstrated a strong predic…
• Cisplatin resistance in oral squamous cell carcinoma: mechanisms, reversal strategies, and emerging technologies.
  2026 · AI Agent 生态 · Cisplatin remains a first-line chemotherapeutic agent in the treatment of oral squamous cell carcinoma (OSCC). However, the efficacy of cisplatin is frequently compromised by the development of drug resistance. This revi…
• Expanding the Toolbox: Utility of HistioTrak for Minimal Residual Monitoring in Pediatric Patients with Langerhans Cell Histiocytosis Treated with Targeted Therapy.
  2026 · AI Agent 生态 · Background/Objectives : Langerhans cell histiocytosis (LCH) is a rare myeloid neoplasm characterized by the clonal proliferation of Langerhans-like dendritic cells and constitutive activation of the mitogen-activated pro…
• Quercetin in skin burn healing: mechanisms, advanced delivery systems, and translational perspectives.
  2026 · AI Agent 生态 · Burn injuries remain a significant global health challenge, often leading to prolonged healing, infection, and scarring. Addressing these complications requires innovative therapeutic strategies that can accelerate tissu…
• Variation in uptake and dose reduction of CDK4/6 inhibitors for the treatment of breast cancer in England, 2019–2024: a descriptive observational study using OpenPrescribing Hospitals
  2026 · AI Agent 生态 · Background The number of novel cancer therapies approved for use in England by the National Institute for Health and Care Excellence is increasing. Monitoring the adoption of new therapies is important to assess equity o…
• Hydrogen supplementation improves glucose-based n-caproate production in Caproiciproducens galactitolivorans with reverse β-oxidation-associated redox remodeling.
  2026 · AI Agent 生态 · Medium-chain carboxylic acids, such as n-caproate, are attractive sustainable platform chemicals. However, their microbial production is often limited by electron availability and low product selectivity. This study inve…
• Application of immune checkpoint inhibitors in hepatocellular carcinoma: a landscape analysis of clinical trial databases.
  2026 · AI Agent 生态 · Background Hepatocellular carcinoma (HCC) is a leading global malignant tumor with poor prognosis. Immune checkpoint inhibitors (ICIs) have become a breakthrough treatment for HCC, but a systematic landscape analysis of …
• The prevalence and risk factors of drug allergy in Sri Lanka-a multi-centre cross-sectional observational study (2024-2025).
  2026 · AI Agent 生态 · Background There is a huge burden of drug allergy (DA) in High-Income Countries and is a major impediment to clinical management, adversely affecting outcomes. Data regarding DA from low-and middle-income countries (LMIC…
• A pan-cancer atlas of metabolic regulatory circuitries integrating multi-omic, immune, and clinical dimensions.
  2026 · AI Agent 生态 · Introduction Metabolic reprogramming is a central determinant of tumor progression, immune evasion, and susceptibility to regulated cell death. However, the integration of metabolic regulation across genomic, multi-omic,…

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